gallic acid has been researched along with Arthritis, Rheumatoid in 6 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate whether gallic acid (3, 4, 5-trihydroxybenzoic acid), a natural polyphenolic acid found in gall nuts, sumac, oak bark, tea leaves, grapes and wine, has pro-apoptotic and anti-inflammatory effects on fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA)." | 7.79 | Gallic acid, a natural polyphenolic acid, induces apoptosis and inhibits proinflammatory gene expressions in rheumatoid arthritis fibroblast-like synoviocytes. ( Chung, SJ; Lee, SK; Lee, SW; Park, MC; Park, YB; Yoon, CH, 2013) |
| "Leonurine treatment significantly decreased the production of pro-inflammatory cytokines (IL-1β, IL-6, IL-8 and TNFα) and MMPs (MMP-1 and MMP-3) and suppressed the migration and invasion of RA fibroblast-like synoviocytes." | 5.46 | Leonurine attenuates fibroblast-like synoviocyte-mediated synovial inflammation and joint destruction in rheumatoid arthritis. ( Jiang, Y; Li, N; Lin, C; Liu, M; Liu, Q; Pan, D; Xu, H; Xu, Q, 2017) |
| "To investigate whether gallic acid (3, 4, 5-trihydroxybenzoic acid), a natural polyphenolic acid found in gall nuts, sumac, oak bark, tea leaves, grapes and wine, has pro-apoptotic and anti-inflammatory effects on fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA)." | 3.79 | Gallic acid, a natural polyphenolic acid, induces apoptosis and inhibits proinflammatory gene expressions in rheumatoid arthritis fibroblast-like synoviocytes. ( Chung, SJ; Lee, SK; Lee, SW; Park, MC; Park, YB; Yoon, CH, 2013) |
| "Methyl gallate (MG) is a plant-derived phenolic compound known to present remarkable anti-inflammatory effect in different experimental models, such as paw oedema, pleurisy, zymosan-induced arthritis and colitis." | 1.72 | Protective effect of methyl gallate on murine antigen-induced arthritis by inhibiting inflammatory process and bone erosion. ( Alabarse, PVG; Amendoeira, FC; Correa, LB; Ferraris, FK; Fukada, SY; Garcia, EB; Henriques, MG; Pádua, TA; Rosas, EC; Saraiva, EM, 2022) |
| "Leonurine treatment significantly decreased the production of pro-inflammatory cytokines (IL-1β, IL-6, IL-8 and TNFα) and MMPs (MMP-1 and MMP-3) and suppressed the migration and invasion of RA fibroblast-like synoviocytes." | 1.46 | Leonurine attenuates fibroblast-like synoviocyte-mediated synovial inflammation and joint destruction in rheumatoid arthritis. ( Jiang, Y; Li, N; Lin, C; Liu, M; Liu, Q; Pan, D; Xu, H; Xu, Q, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Correa, LB | 1 |
| Pádua, TA | 1 |
| Alabarse, PVG | 1 |
| Saraiva, EM | 1 |
| Garcia, EB | 1 |
| Amendoeira, FC | 1 |
| Ferraris, FK | 1 |
| Fukada, SY | 1 |
| Rosas, EC | 1 |
| Henriques, MG | 1 |
| Liu, S | 1 |
| Li, J | 2 |
| Feng, LH | 1 |
| Du, YY | 1 |
| Chen, ZX | 1 |
| Liu, MY | 1 |
| Liu, QP | 1 |
| Lin, CS | 1 |
| Chu, CQ | 1 |
| Xu, Q | 2 |
| Li, N | 1 |
| Liu, Q | 1 |
| Pan, D | 1 |
| Jiang, Y | 1 |
| Liu, M | 2 |
| Xu, H | 1 |
| Lin, C | 1 |
| Liu, W | 1 |
| Yoon, CH | 1 |
| Chung, SJ | 1 |
| Lee, SW | 1 |
| Park, YB | 1 |
| Lee, SK | 1 |
| Park, MC | 1 |
6 other studies available for gallic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Protective effect of methyl gallate on murine antigen-induced arthritis by inhibiting inflammatory process and bone erosion.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Gallic Acid; Male; Mice; Mice, Inbred C57BL | 2022 |
Gallic acid regulates immune response in a mouse model of rheumatoid arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cytokines; Disease Models, Animal; Gallic A | 2023 |
Leonurine Regulates Treg/Th17 Balance to Attenuate Rheumatoid Arthritis Through Inhibition of TAZ Expression.
Topics: Acyltransferases; Arthritis, Rheumatoid; Biomarkers; CD4-Positive T-Lymphocytes; Gallic Acid; Gene E | 2020 |
Leonurine attenuates fibroblast-like synoviocyte-mediated synovial inflammation and joint destruction in rheumatoid arthritis.
Topics: Adult; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cytokines; Female; Fibroblasts; Gall | 2017 |
Theaflavin-3, 3'-Digallate Attenuates Rheumatoid Inflammation in Mice Through the Nuclear Factor-κB and MAPK Pathways.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Biflavonoids; Cat | 2019 |
Gallic acid, a natural polyphenolic acid, induces apoptosis and inhibits proinflammatory gene expressions in rheumatoid arthritis fibroblast-like synoviocytes.
Topics: Apoptosis; Arthritis, Rheumatoid; Cell Survival; Cells, Cultured; Fibroblasts; Gallic Acid; Gene Exp | 2013 |