Page last updated: 2024-10-17

gallic acid and Apoplexy

gallic acid has been researched along with Apoplexy in 8 studies

gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.

Research Excerpts

ExcerptRelevanceReference
" Protective effects from gallic acid (GA) in cerebral ischemia/re-perfusion-induced injury to the BBB and other sites in the brain have not yet been assessed."8.12Gallic acid attenuates cerebral ischemia/re-perfusion-induced blood-brain barrier injury by modifying polarization of microglia. ( Mao, Y; Qu, Y; Wang, L, 2022)
"Leonurine has been shown to trigger antioxidant responses during ischemic stroke, and nuclear factor erythroid 2-related factor 2 (Nrf-2) imparts protective effects against oxidative injury."7.91Protective effects of leonurine against ischemic stroke in mice by activating nuclear factor erythroid 2-related factor 2 pathway. ( Chen, YX; He, JN; Xie, YZ; Yang, Y; Zhang, C; Zhang, XJ, 2019)
"Leonurine significantly alleviated neurological deficit, decreased brain water content and infarct volume after ischemic stroke, which was accompanied by decreased levels of MDA and Bax, increased activities of SOD, CAT, UCP4, and Bcl-2, and restored ultrastructure of mitochondria."7.78Leonurine protects brain injury by increased activities of UCP4, SOD, CAT and Bcl-2, decreased levels of MDA and Bax, and ameliorated ultrastructure of mitochondria in experimental stroke. ( Cao, X; Dong, L; Du, Y; Ji, H; Ji, Y; Li, L; Li, S; Liu, H; Wang, C; Xing, Y; Zhang, X; Zhao, K, 2012)
" Protective effects from gallic acid (GA) in cerebral ischemia/re-perfusion-induced injury to the BBB and other sites in the brain have not yet been assessed."4.12Gallic acid attenuates cerebral ischemia/re-perfusion-induced blood-brain barrier injury by modifying polarization of microglia. ( Mao, Y; Qu, Y; Wang, L, 2022)
"Leonurine has been shown to trigger antioxidant responses during ischemic stroke, and nuclear factor erythroid 2-related factor 2 (Nrf-2) imparts protective effects against oxidative injury."3.91Protective effects of leonurine against ischemic stroke in mice by activating nuclear factor erythroid 2-related factor 2 pathway. ( Chen, YX; He, JN; Xie, YZ; Yang, Y; Zhang, C; Zhang, XJ, 2019)
"Leonurine significantly alleviated neurological deficit, decreased brain water content and infarct volume after ischemic stroke, which was accompanied by decreased levels of MDA and Bax, increased activities of SOD, CAT, UCP4, and Bcl-2, and restored ultrastructure of mitochondria."3.78Leonurine protects brain injury by increased activities of UCP4, SOD, CAT and Bcl-2, decreased levels of MDA and Bax, and ameliorated ultrastructure of mitochondria in experimental stroke. ( Cao, X; Dong, L; Du, Y; Ji, H; Ji, Y; Li, L; Li, S; Liu, H; Wang, C; Xing, Y; Zhang, X; Zhao, K, 2012)
"Male Sprague-Dawley rats under permanent middle cerebral artery occlusion (pMCAO) model, randomly assigned as: model, sham, nimodipine (0."3.11The therapeutic role of Jingchuan tablet on ischaemic cerebral stroke via the HIF-1α/EPO/VEGFA signalling pathway. ( Fu, Y; Li, D; Liu, Q; Wang, H; Wang, W; Zhang, T; Zhang, Y, 2022)
"Ischemic stroke is a leading cause of death worldwide, and it remains an urgent task to develop novel and alternative therapeutic strategies for the disease."1.72Discovery of anti-stroke active substances in Guhong injection based on multi-phenotypic screening of zebrafish. ( Li, X; Sheng, H; Wang, Y; Wu, H; Zhao, L, 2022)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Qu, Y1
Wang, L1
Mao, Y1
Wang, Y4
Wu, H1
Sheng, H1
Li, X1
Zhao, L1
Zhang, Y1
Liu, Q1
Zhang, T1
Wang, H1
Fu, Y1
Wang, W1
Li, D1
Zhang, QY1
Wang, ZJ1
Sun, DM1
Xu, P1
Wu, WJ1
Liu, XH1
Zhu, YZ1
Xie, YZ1
Zhang, XJ1
Zhang, C1
Yang, Y1
He, JN1
Chen, YX1
Nabavi, SF1
Habtemariam, S1
Di Lorenzo, A1
Sureda, A1
Khanjani, S1
Nabavi, SM1
Daglia, M1
Liu, H1
Zhang, X2
Du, Y1
Ji, H1
Li, S1
Li, L1
Xing, Y1
Dong, L1
Wang, C1
Zhao, K1
Ji, Y1
Cao, X1
Shirakawa, H1
Koseki, T1
Ohinata, K1
Hashizume, K1
Komai, M1

Trials

1 trial available for gallic acid and Apoplexy

ArticleYear
The therapeutic role of Jingchuan tablet on ischaemic cerebral stroke via the HIF-1α/EPO/VEGFA signalling pathway.
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Animals; Brain Ischemia; Chlorogenic Acid; Disease Models, Animal; Gallic Acid; Infarction, Middle C

2022

Other Studies

7 other studies available for gallic acid and Apoplexy

ArticleYear
Gallic acid attenuates cerebral ischemia/re-perfusion-induced blood-brain barrier injury by modifying polarization of microglia.
    Journal of immunotoxicology, 2022, Volume: 19, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Gallic Acid; Infarction, Middle Cerebral Artery; Mice;

2022
Discovery of anti-stroke active substances in Guhong injection based on multi-phenotypic screening of zebrafish.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 155

    Topics: Animals; Brain Ischemia; Chlorogenic Acid; Cytokines; Gallic Acid; Ischemic Stroke; Mice; Molecular

2022
Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain; Cell Survival; Gallic Acid; L-Lactate Dehydr

2017
Protective effects of leonurine against ischemic stroke in mice by activating nuclear factor erythroid 2-related factor 2 pathway.
    CNS neuroscience & therapeutics, 2019, Volume: 25, Issue:9

    Topics: Animals; Brain Ischemia; Gallic Acid; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Neuroprotective

2019
Post-Stroke Depression Modulation and in Vivo Antioxidant Activity of Gallic Acid and Its Synthetic Derivatives in a Murine Model System.
    Nutrients, 2016, Apr-28, Volume: 8, Issue:5

    Topics: Animals; Antioxidants; Depression; Gallic Acid; Humans; Injections, Intraperitoneal; Male; Mice; Mic

2016
Leonurine protects brain injury by increased activities of UCP4, SOD, CAT and Bcl-2, decreased levels of MDA and Bax, and ameliorated ultrastructure of mitochondria in experimental stroke.
    Brain research, 2012, Sep-20, Volume: 1474

    Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Brain Injuries; Catalase; Disease Models, An

2012
Rice bran fractions improve blood pressure, lipid profile, and glucose metabolism in stroke-prone spontaneously hypertensive rats.
    Journal of agricultural and food chemistry, 2006, Mar-08, Volume: 54, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Blood Glucose; Blood Pressure; Catechin; Deoxyguanosine; Diet;

2006