gallic acid has been researched along with Acute Liver Injury, Drug-Induced in 36 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gallic acid (GA) is an important phenolic compound, which could protect different tissues from oxidative stress induced damage." | 1.62 | Gallic acid ameliorates sodium arsenite-induced renal and hepatic toxicity in rats. ( Gholamine, B; Goudarzi, M; Hosseinzadeh, A; Houshmand, G; Kalantar, M; Mehrzadi, S, 2021) |
| " Nevertheless, low solubility and bioavailability hamper the application of SA." | 1.56 | Development of TPGS/F127/F68 mixed polymeric micelles: Enhanced oral bioavailability and hepatoprotection of syringic acid against carbon tetrachloride-induced hepatotoxicity. ( Adu-Frimpong, M; Deng, W; Li, W; Li, Y; Ma, P; Sun, C; Xu, X; Yu, J; Zhang, H; Zhu, Y, 2020) |
| "The treatment with gallic acid showed significant ameliorations in abnormalities of fluoxetine-induced liver injury as represented by the improvement of hepatic CAT, SOD activities, vitamin C levels, serum biochemical parameters, and histopathological changes, in addition to the recovery of antioxidant defense system status." | 1.46 | Anti-inflammatory and ameliorative effects of gallic acid on fluoxetine-induced oxidative stress and liver damage in rats. ( Amini, SA; Heidarian, E; Karimi-Khouzani, O, 2017) |
| "Metastasis is the main cause of cancer-related death and requires the development of effective treatments with reduced toxicity and effective anticancer activity." | 1.46 | Solid lipid nanoparticles improve octyl gallate antimetastatic activity and ameliorate its renal and hepatic toxic effects. ( Cordova, CAS; Creczynski-Pasa, TB; Jasper, R; Locatelli, C; Mascarello, A; Nunes, RJ; Silva, AH; Winter, E; Yunes, RA; Zanetti-Ramos, BG, 2017) |
| "Gallic acid (100 microM) was more effective than aqueous extracts of Rhus coriaria L." | 1.36 | A search for hepatoprotective activity of aqueous extract of Rhus coriaria L. against oxidative stress cytotoxicity. ( Eskandari, MR; Kamalinejad, M; Pourahmad, J; Shakibaei, R, 2010) |
| "Acetaminophen is a commonly used drug for the treatment of patients with common cold and influenza." | 1.35 | Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1. ( Chan, AK; Chan, AS; Cheng, CH; Cheng, GY; Chui, CH; Fong, DW; Gambari, R; Hau, DK; Kan, CW; Kok, SH; Lai, PB; Lau, FY; Leung, AK; Tang, JC; Tong, CS; Wong, RS; Wong, WY; Yuen, MC; Zhu, GY, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.89) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 6 (16.67) | 29.6817 |
| 2010's | 14 (38.89) | 24.3611 |
| 2020's | 9 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salama, SA | 1 |
| Abdel-Bakky, MS | 1 |
| Mohamed, AA | 1 |
| Gheena, S | 1 |
| Ezhilarasan, D | 1 |
| Shree Harini, K | 1 |
| Rajeshkumar, S | 1 |
| Doğan, D | 1 |
| Meydan, İ | 1 |
| Kömüroğlu, AU | 1 |
| Sun, C | 1 |
| Li, W | 1 |
| Ma, P | 1 |
| Li, Y | 1 |
| Zhu, Y | 1 |
| Zhang, H | 1 |
| Adu-Frimpong, M | 1 |
| Deng, W | 1 |
| Yu, J | 1 |
| Xu, X | 1 |
| Owumi, SE | 1 |
| Nwozo, SO | 1 |
| Effiong, ME | 1 |
| Najophe, ES | 1 |
| Liu, F | 1 |
| Jiang, FB | 1 |
| Li, YT | 1 |
| Liu, RM | 1 |
| Wu, ZY | 1 |
| Yan, CW | 1 |
| Aladesanmi, OO | 1 |
| Akinmoladun, AC | 1 |
| Josiah, SS | 1 |
| Olaleye, MT | 1 |
| Akindahunsi, AA | 1 |
| Sanjay, S | 1 |
| Girish, C | 1 |
| Toi, PC | 1 |
| Bobby, Z | 1 |
| Perazzoli, MR | 1 |
| Perondi, CK | 1 |
| Baratto, CM | 1 |
| Winter, E | 2 |
| Creczynski-Pasa, TB | 2 |
| Locatelli, C | 2 |
| Karimi-Khouzani, O | 1 |
| Heidarian, E | 1 |
| Amini, SA | 1 |
| Omobowale, TO | 1 |
| Oyagbemi, AA | 1 |
| Ajufo, UE | 1 |
| Adejumobi, OA | 1 |
| Ola-Davies, OE | 1 |
| Adedapo, AA | 1 |
| Yakubu, MA | 1 |
| Cordova, CAS | 1 |
| Silva, AH | 1 |
| Zanetti-Ramos, BG | 1 |
| Jasper, R | 1 |
| Mascarello, A | 1 |
| Yunes, RA | 1 |
| Nunes, RJ | 1 |
| Feng, RB | 1 |
| Wang, Y | 1 |
| He, C | 1 |
| Yang, Y | 1 |
| Wan, JB | 1 |
| Safaei, F | 1 |
| Mehrzadi, S | 2 |
| Khadem Haghighian, H | 1 |
| Hosseinzadeh, A | 2 |
| Nesari, A | 1 |
| Dolatshahi, M | 1 |
| Esmaeilizadeh, M | 1 |
| Goudarzi, M | 2 |
| Gholamine, B | 1 |
| Houshmand, G | 1 |
| Kalantar, M | 1 |
| Abarikwu, SO | 1 |
| Durojaiye, M | 1 |
| Alabi, A | 1 |
| Asonye, B | 1 |
| Akiri, O | 1 |
| Al-Sayed, E | 1 |
| Esmat, A | 1 |
| Sachdeva, M | 1 |
| Chadha, R | 1 |
| Kumar, A | 1 |
| Karan, M | 1 |
| Singh, T | 1 |
| Dhingra, S | 1 |
| Wang, P | 1 |
| Gao, YM | 1 |
| Sun, X | 1 |
| Guo, N | 1 |
| Li, J | 1 |
| Wang, W | 1 |
| Yao, LP | 1 |
| Fu, YJ | 1 |
| Tung, YT | 1 |
| Wu, JH | 1 |
| Huang, CC | 1 |
| Peng, HC | 1 |
| Chen, YL | 1 |
| Yang, SC | 1 |
| Chang, ST | 1 |
| Hau, DK | 1 |
| Gambari, R | 1 |
| Wong, RS | 1 |
| Yuen, MC | 1 |
| Cheng, GY | 1 |
| Tong, CS | 1 |
| Zhu, GY | 1 |
| Leung, AK | 1 |
| Lai, PB | 1 |
| Lau, FY | 1 |
| Chan, AK | 1 |
| Wong, WY | 1 |
| Kok, SH | 1 |
| Cheng, CH | 1 |
| Kan, CW | 1 |
| Chan, AS | 1 |
| Chui, CH | 1 |
| Tang, JC | 1 |
| Fong, DW | 1 |
| Zeashan, H | 1 |
| Amresh, G | 1 |
| Singh, S | 1 |
| Rao, CV | 1 |
| Itoh, A | 1 |
| Isoda, K | 1 |
| Kondoh, M | 1 |
| Kawase, M | 1 |
| Kobayashi, M | 1 |
| Tamesada, M | 1 |
| Yagi, K | 1 |
| Pourahmad, J | 1 |
| Eskandari, MR | 1 |
| Shakibaei, R | 1 |
| Kamalinejad, M | 1 |
| Rasool, MK | 1 |
| Sabina, EP | 1 |
| Ramya, SR | 1 |
| Preety, P | 1 |
| Patel, S | 1 |
| Mandal, N | 1 |
| Mishra, PP | 1 |
| Samuel, J | 1 |
| Duh, PD | 1 |
| Lin, SL | 1 |
| Wu, SC | 1 |
| Ramachandran, V | 1 |
| Raja, B | 1 |
| WIGGLESWORTH, JS | 1 |
| Peyrin-Biroulet, L | 1 |
| Petitpain, N | 1 |
| Kalt, P | 1 |
| Ancel, D | 1 |
| Petit-Laurent, F | 1 |
| Trechot, P | 1 |
| Barraud, H | 1 |
| Bronowicki, JP | 1 |
| Shimoda, H | 1 |
| Tanaka, J | 1 |
| Kikuchi, M | 1 |
| Fukuda, T | 1 |
| Ito, H | 1 |
| Hatano, T | 1 |
| Yoshida, T | 1 |
| Texl, A | 1 |
| Konecný, M | 1 |
| Anand, KK | 1 |
| Singh, B | 1 |
| Saxena, AK | 1 |
| Chandan, BK | 1 |
| Gupta, VN | 1 |
| Bhardwaj, V | 1 |
| Kanai, S | 1 |
| Okano, H | 1 |
| Torrielli, MV | 1 |
| Ugazio, G | 1 |
| Lu, XY | 1 |
| Chen, WW | 1 |
| Harris, PA | 1 |
| Zboralske, FF | 1 |
| Rambo, ON | 1 |
| Margulis, AR | 1 |
| Riegelmen, S | 1 |
36 other studies available for gallic acid and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Upregulation of Nrf2 signaling and suppression of ferroptosis and NF-κB pathway by leonurine attenuate iron overload-induced hepatotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Ferroptosis; Gallic Acid; Iron Overload; Male; NF-E | 2022 |
Syringic acid and silymarin concurrent administration inhibits sodium valproate-induced liver injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Chemical an | 2022 |
Protective Effect of Silymarin and Gallic Acid against Cisplatin-Induced Nephrotoxicity and Hepatotoxicity.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cisplatin; Gallic Acid; Glutathione; | 2022 |
Development of TPGS/F127/F68 mixed polymeric micelles: Enhanced oral bioavailability and hepatoprotection of syringic acid against carbon tetrachloride-induced hepatotoxicity.
Topics: Administration, Oral; Animals; Biological Availability; Carbon Tetrachloride; Chemical and Drug Indu | 2020 |
Gallic acid and omega-3 fatty acids decrease inflammatory and oxidative stress in manganese-treated rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Fatty Acids, Omega-3; Gallic Acid; Inflammation; Ki | 2020 |
Cocrystallization with syringic acid presents a new opportunity for effectively reducing the hepatotoxicity of isoniazid.
Topics: Animals; Chemical and Drug Induced Liver Injury; Crystallization; Drug-Related Side Effects and Adve | 2020 |
Modulatory activities of polyphenols on crude acetylene-induced cardiac and hepatic dysfunctions in a rat model.
Topics: Acetylene; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Gallic Acid; Lipid Peroxid | 2022 |
Gallic acid attenuates isoniazid and rifampicin-induced liver injury by improving hepatic redox homeostasis through influence on Nrf2 and NF-κB signalling cascades in Wistar Rats.
Topics: Animals; Antibiotics, Antitubercular; Chemical and Drug Induced Liver Injury; Gallic Acid; Isoniazid | 2021 |
Gallic Acid and Dodecyl Gallate Prevents Carbon Tetrachloride-Induced Acute and Chronic Hepatotoxicity by Enhancing Hepatic Antioxidant Status and Increasing p53 Expression.
Topics: Acute Disease; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 2017 |
Anti-inflammatory and ameliorative effects of gallic acid on fluoxetine-induced oxidative stress and liver damage in rats.
Topics: Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Dose-Response Relationshi | 2017 |
Ameliorative Effect of Gallic Acid in Doxorubicin-Induced Hepatotoxicity in Wistar Rats Through Antioxidant Defense System.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Bilirubin; Catalase; Chemical and | 2018 |
Solid lipid nanoparticles improve octyl gallate antimetastatic activity and ameliorate its renal and hepatic toxic effects.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorocebus aethiops; Female; Gallic Acid; Kidney D | 2017 |
Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response.
Topics: Antioxidants; Cell Line; Chemical and Drug Induced Liver Injury; Extracellular Signal-Regulated MAP | 2018 |
Protective effects of gallic acid against methotrexate-induced toxicity in rats.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Biomarkers; Biopsy | 2018 |
Gallic acid ameliorates sodium arsenite-induced renal and hepatic toxicity in rats.
Topics: Animals; Antioxidants; Arsenites; Catalase; Chemical and Drug Induced Liver Injury; Dose-Response Re | 2021 |
Curcumin protects against gallic acid-induced oxidative stress, suppression of glutathione antioxidant defenses, hepatic and renal damage in rats.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Curcumin; Gallic Acid; Glutathione; K | 2016 |
Hepatoprotective and antioxidant effect of ellagitannins and galloyl esters isolated from Melaleuca styphelioides on carbon tetrachloride-induced hepatotoxicity in HepG2 cells.
Topics: Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; C | 2016 |
Hepatoprotective effect of trimethylgallic acid esters against carbon tetrachloride-induced liver injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Carbon Tetrachloride; Chemical and Drug | 2015 |
Hepatoprotective effect of 2'-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway.
Topics: Animals; Antioxidant Response Elements; Antioxidants; Apoptosis; Carbon Tetrachloride; Chemical and | 2017 |
Protective effect of Acacia confusa bark extract and its active compound gallic acid against carbon tetrachloride-induced chronic liver injury in rats.
Topics: Acacia; Animals; Antioxidants; Blotting, Western; Carbon Tetrachloride Poisoning; Chemical and Drug | 2009 |
Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1 Inhibitors; | 2009 |
Hepatoprotective and antioxidant activity of Amaranthus spinosus against CCl4 induced toxicity.
Topics: Amaranthus; Animals; Antioxidants; Butylated Hydroxyanisole; Carbon Tetrachloride Poisoning; Cell Li | 2009 |
Hepatoprotective effect of syringic acid and vanillic acid on concanavalin a-induced liver injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; | 2009 |
A search for hepatoprotective activity of aqueous extract of Rhus coriaria L. against oxidative stress cytotoxicity.
Topics: Animals; Benzene Derivatives; Cell Survival; Chemical and Drug Induced Liver Injury; Fruit; Gallic A | 2010 |
Hepatoprotective and antioxidant effects of gallic acid in paracetamol-induced liver damage in mice.
Topics: Acetaminophen; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Gallic Acid; Lipid Per | 2010 |
Hepatoprotection of Graptopetalum paraguayense E. Walther on CCl₄-induced liver damage and inflammation.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; | 2011 |
Protective effects of syringic acid against acetaminophen-induced hepatic damage in albino rats.
Topics: Acetaminophen; Administration, Oral; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liv | 2010 |
THE USE OF THE OSMIUM-ETHYL GALLATE TECHNIQUE IN THE STUDY OF CARBON TETRACHLORIDE LIVER INJURY.
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Gallic | 1964 |
[Probable hepatoxicity from epigallocatecol gallate used for phytotherapy].
Topics: Anti-Obesity Agents; Chemical and Drug Induced Liver Injury; Female; Gallic Acid; Humans; Middle Age | 2004 |
Walnut polyphenols prevent liver damage induced by carbon tetrachloride and d-galactosamine: hepatoprotective hydrolyzable tannins in the kernel pellicles of walnut.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Flavonoids; | 2008 |
[Contribution to the hepatoxic effect of tannin and Rectobaryum].
Topics: Animals; Barium Sulfate; Chemical and Drug Induced Liver Injury; Contrast Media; Female; Gallic Acid | 1967 |
3,4,5-Trihydroxy benzoic acid (gallic acid), the hepatoprotective principle in the fruits of Terminalia belerica-bioassay guided activity.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; Gallic Acid | 1997 |
Mechanism of the protective effects of sumac gall extract and gallic acid on the progression of CCl4-induced acute liver injury in rats.
Topics: Acute Disease; Administration, Inhalation; Administration, Oral; Animals; Carbon Tetrachloride; Chem | 1998 |
Biochemical aspects of the protective action of propyl gallate on liver injury in rats poisoned with carbon tetrachloride.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body Temperature; | 1975 |
[Protective effects of propyl gallate on acute liver injury induced by ethanol in mice and rats].
Topics: Animals; Chemical and Drug Induced Liver Injury; Ethanol; Gallic Acid; Lipid Peroxides; Liver Diseas | 1987 |
Toxicity studies on tannic acid administered by enema. II. The colonic absorption and intraperitoneal toxicity of tannic acid and its hydrolytic products in rats.
Topics: Animals; Blood; Cathartics; Chemical and Drug Induced Liver Injury; Colon; Enema; Gallic Acid; Injec | 1966 |