galantamine has been researched along with Alzheimer Disease in 638 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 15 (2.35) | 18.2507 |
2000's | 317 (49.69) | 29.6817 |
2010's | 236 (36.99) | 24.3611 |
2020's | 70 (10.97) | 2.80 |
Authors | Studies |
---|---|
Bores, GM; Effland, RC; Fink, DM; Huger, FP; Kurys, BE; Rush, DK; Selk, DE | 1 |
Greenblatt, HM; Kryger, G; Lewis, T; Silman, I; Sussman, JL | 1 |
Bartolucci, C; Fels, G; Lamba, D; Perola, E; Pilger, C | 1 |
Ingkaninan, K; Khorana, N; Markmee, S; Prachyawarakorn, V; Ruchirawat, S | 1 |
Decker, M; Lehmann, J; Rommelspacher, H; Schott, Y | 1 |
Ge, H; Lin, C; Ma, L; Peng, W; Song, H; Wang, Z; Wen, H; Zhou, Y | 1 |
Andrisano, V; Banzi, R; Bartolini, M; Bergamini, C; Bolognesi, ML; Cattaneo, A; Cavalli, A; Fato, R; Hrelia, P; Lenaz, G; Melchiorre, C; Minarini, A; Recanatini, M; Rosini, M; Tarozzi, A; Tumiatti, V | 1 |
Gaube, F; Heilmann, J; Lehmann, J; Rook, Y; Schepmann, D; Schmidtke, KU; Winckler, T; Wünsch, B | 1 |
de Los Ríos, C; Egea, J; Gálvez, E; García, AG; Iriepa, I; León, R; López, MG; Marco-Contelles, J; Moraleda, I; Romero, A; Samadi, A; Villarroya, M | 1 |
Harding, WW; McAnuff, MA; Pecic, S | 1 |
Alvarez-Pérez, M; Chioua, M; Gandía, L; García, AG; González-Lafuente, L; López, MG; Marco-Contelles, J; Ríos, Cde L; Roda, JM; Romero, A; Samadi, A; Soriano, E; Villarroya, M | 1 |
Al-Rashid, ZF; Hsung, RP | 1 |
Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
Boido, V; Carotti, A; Catto, M; Giangreco, I; Nicolotti, O; Novelli, F; Pisani, L; Sparatore, A; Sparatore, F; Tasso, B; Tonelli, M | 1 |
Ding, K; Huang, L; Jiang, H; Li, X; Luo, Z; Su, T; Wang, X | 1 |
Huang, L; Li, XS; Mao, F; Meng, FC; Qin, F; Shan, WJ | 1 |
Beazely, MA; Mohamed, T; Rao, PP; Vasefi, MS; Yeung, JC | 1 |
Bottegoni, G; Cavalli, A; Daniele, S; Goldoni, L; Martini, C; Melchiorre, C; Piomelli, D; Pizzirani, D; Reggiani, A; Rosini, M; Simoni, E; Tarozzo, G; Trincavelli, ML | 1 |
Carotti, A; Catto, M; Cellamare, S; Leonetti, F; Nicolotti, O; Pesce, P; Pisani, L; Stefanachi, A | 1 |
Hu, XJ; Kong, LY; Li, RS; Wang, XB | 1 |
Bag, S; Foster, M; Ghosh, S; LeVine, H; Schifone, C; Sood, A; Török, B; Török, M; Tulsan, R; Zhou, W | 1 |
Kong, LY; Li, JY; Wang, XB; Xie, SS; Yang, L | 1 |
Jiang, N; Kong, LY; Li, SY; Sun, HB; Wang, KD; Wang, XB; Xie, SS; Yao, HQ | 1 |
Boonyarat, C; Reubroycharoen, P; Thiratmatrakul, S; Tohda, M; Vajragupta, O; Waiwut, P; Yenjai, C | 1 |
Adam, BL; Gao, J; Terry, AV | 1 |
Chen, Y; Fang, L; Fang, X; Fleck, C; Gou, S; Huang, Z; Lenhardt, I; Lupp, A; Sun, Y; Zhang, Y | 1 |
Kong, LY; Li, SY; Wang, XB; Xie, SS; Xu, ZC; Yu, WY | 1 |
Kong, LY; Lan, JS; Li, SY; Pan, LF; Wang, XB; Xie, SS | 1 |
Kim, JM; Kim, NJ; Lee, YH; Lee, YS; Ryu, JH; Seo, JM; Shin, MC; Shin, SY; Yun, YD | 1 |
Bag, S; Cho, H; LeVine, H; Redjeb, H; Sood, A; Török, B; Török, M; Tulsan, R; Zhou, W | 1 |
Cahlíková, L; Chlebek, J; Hošt'álková, A; Opletal, L; Pérez, DI; Šafratová, M; Štěpánková, Š | 1 |
Basile, L; Gazioglu, I; Ginex, T; Guccione, S; Kucukislamoglu, M; Kurt, BZ; Sonmez, F | 1 |
Amooru, GD; Ampasala, DR; Darla, MM; Devineni, SR; Eadlapalli, S; Kotapati, KV; Palaka, BK; Penumala, M; Shaik, JB; Vadde, R | 1 |
Andrisano, V; Bartolini, M; Bolognesi, ML; Brand, GD; Castro, NG; da Silva Boni, M; da Silva, FMR; de Andrade Ramos, G; de Castro Couto, G; de Oliveira, AS; do Nascimento Nogueira, PC; Guimarães, MJR; Korábečný, J; Lemes, LFN; Romeiro, LAS; Romeiro, NC; Silveira, ER; Soukup, O; Souza, INO | 1 |
Amooru Gangaiah, D; Ampasala, DR; Darla Mark, M; Eadlapalli, S; Palaka, BK; Penumala, M; Shaik, JB; Vadde, R | 1 |
Hoda, N; Jameel, E; Jayaram, B; Kumar, J; Maqbool, M; Meena, P; Mobashir, M; Shandilya, A; Singh, A; Tiwari, M | 1 |
Arantes, S; Bacalhau, P; Burke, AJ; Caldeira, AT; Goth, A; Guarda, C; Marques, CS; Martins, R; Peixoto, D; San Juan, AA; Silva, M | 1 |
Beazely, MA; Mohamed, T; Osman, W; Rao, PP; Sit, VM; Vasefi, MS | 1 |
Cañadas, S; García-Font, N; Iodice, C; Marco-Contelles, J; Oset-Gasque, MJ; Pejin, B; Tommonaro, G; Vitale, RM | 1 |
Brazzolotto, X; Chan, S; De la Mora, E; Deora, GS; Dighe, SN; Nachon, F; Parat, MO; Ross, BP | 1 |
Dikmen, M; Karaküçük-İyidoğan, A; Karaman, N; Koçyiğit-Kaymakçıoğlu, B; Oruç-Emre, EE; Öztürk, M; Sıcak, Y; Taşkın-Tok, T | 1 |
Barbosa, FAR; Braga, AL; Canto, RFS; Rafique, J; Saba, S | 1 |
Altomare, CD; Cellamare, S; de Candia, M; Denora, N; Majellaro, M; Tricarico, D; Zaetta, G | 1 |
Cordier, W; Nell, M; Panayides, JL; Riley, DL; Steenkamp, V; van der Westhuyzen, C; van Greunen, DG | 1 |
Basiri, A; Byrareddy, SN; Conda-Sheridan, M; Dutta, D; McCarthy, A; Xiao, M | 1 |
Horton, W; Kugyela, N; Kulkarni, A; LeVine, H; Peerannawar, S; Sood, A; Soule, J; Török, B; Török, M; Tran, CD; Tulsan, R | 1 |
Akram, MS; Rashid, U; Sadiq, A; Sarfraz, M; Sultana, N; Tariq, MI | 1 |
Darekar, MN; Gurjar, AS; Ooi, L; Yeong, KY | 1 |
Brazzolotto, X; Colletier, JP; Coquelle, N; Gobec, S; Jukič, M; Knez, D; Kos, J; Mravljak, J; Nachon, F; Pišlar, A; Sova, M; Žakelj, S | 1 |
Akbarzadeh, T; Amini, M; Asadi, M; Bukhari, SNA; Ghobadian, R; Khaleghzadeh-Ahangar, H; Mahdavi, M; Moradi, A; Nadri, H; Sharifzadeh, M | 1 |
Andrisano, V; Cahlikova, L; Hostalkova, A; Hulcova, D; Jun, D; Korabecny, J; Kucera, T; Kunes, J; Marikova, J; Novakova, L; Opletal, L; Perez, DI; Siatka, T | 1 |
Kumar, A; Mishra, P; Panda, G | 1 |
Cai, R; Dong, YF; Geng, SQ; Liu, YM; Wang, LN; Zhu, J | 1 |
Bartolini, M; Belluti, F; Bisi, A; Di Marzo, V; Gobbi, S; Iriepa, I; Ligresti, A; Mahmoud, AM; Montanari, S; Monti, B; Moraleda, I; Naldi, M; Petralla, S; Pruccoli, L; Rabbito, A; Rampa, A; Tarozzi, A | 1 |
Cordier, W; Johan van der Westhuizen, C; Nell, M; Panayides, JL; Riley, DL; Stander, A; Steenkamp, V; van Greunen, DG | 1 |
Ji, J; Peng, Y; Rakesh, KP; Wang, S; Xu, M; Zhu, L | 1 |
Bartolini, M; Bolognesi, ML; Fernández-Bolaños, JG; Franconetti, A; Hicke, J; Lagunes, I; López, Ó; Maya, I; Monti, B; Naldi, M; Padrón, JM; Petralla, S; Poeta, E; Roldán-Peña, JM; Romero-Real, V | 1 |
Cahlíková, L; Carmen Catapano, M; Hulcová, D; Janoušek, J; Jenčo, J; Kohelová, E; Korábečný, J; Kučera, T; Kuneš, J; Maafi, N; Maříková, J; Mecava, M; Nováková, L; Pidaný, F; Prchal, L; Schmidt, M; Shammari, LA; Špulák, M | 1 |
Alcaro, S; Bagetta, D; Burke, AJ; Carreiro, EP; Fernández-Bolaños, JG; Hagenow, S; Leitzbach, L; López, Ó; Marques, C; Moutayakine, A; Stark, H | 1 |
Alexandrova, A; Georgieva, A; Kalfin, R; Lazarova, M; Petkova-Kirova, P; Stefanova, M; Tancheva, L; Tsekova, D; Tsvetanova, E; Uzunova, D; Vezenkov, L | 1 |
Celik Topkara, K; Cetinkaya, A; Demir, S; Kilinc, E; Saylan, A | 1 |
Ai, Y; Cheng, Y; Fan, F; Liu, H; Liu, Q; Shi, X | 1 |
Baakman, AC; Bajenaru, O; Broekhuizen, K; Camps, L; Cohen, A; de Kam, M; Gavan, C; Groeneveld, GJ; Kalisvaart, K; Lemstra, E; Scheltens, P; Schoonenboom, N; Swart, EL; van Doeselaar, L; van Gerven, J | 1 |
Ajavakom, V; Bellingham, RK; Brown, RCD; Camp, NP; Kemp, SC; McLean, NJ; Miller, IR; Moustafa, GAI | 1 |
Cui, Y; Ren, G; Shi, X; Xu, Z | 1 |
Bak, SH; Byeon, GH; Byun, J; Choi, HS; Chun, IK; Heo, J; Hong, Y; Jang, JW; Jeong, CW; Kasani, PH; Kim, JA; Kim, JH; Kim, JK; Kim, KL; Kim, S; Kim, WJ; Kim, Y; Kwon, SO; Lee, DY; Lee, EJ; Lee, K; Lee, SA; Moon, KW; Nam, SJ; Park, JI; Park, SW; Park, YJ; Rhee, HY | 1 |
Aarsland, D; Andersson, T; Berglund, A; Cummings, J; Freund-Levi, Y; Holmgren, S | 1 |
Şahin, S | 1 |
Ashoor, HM; Clarke, M; Hemmelgarn, BR; Holroyd-Leduc, J; Mavridis, D; Rios, P; Seitidis, G; Stewart, L; Straus, SE; Tricco, AC; Tudur-Smith, C; Veroniki, AA | 1 |
Abbasi, Z; Kalari, M; Khaleghian, A; Moosavi-Nejad, Z; Shasaltaneh, MD | 1 |
Atanasov, A; Danalev, DL; Iwanov, I; Karadjova, V; Lozanov, V; Todorova, R; Vassilev, N; Vezenkov, LT | 1 |
Lamba, D; Pesaresi, A | 1 |
Allam, M; El-Ganainy, SO; Elbahnasi, AI; Ghazy, AA; Gowayed, MA; Mansour, AM; Soliman, OA | 1 |
Atanasova, M; Berkov, S; Dimitrov, I; Doytchinova, I; Georgiev, B; Ivanov, S; Zheleva-Dimitrova, D | 1 |
Boonprasert, R; Bunditvorapoom, D; Kaewsutthi, S; Kijsanayotin, P; Limwongse, C; Senanarong, V; Yaowaluk, T | 1 |
Aparasu, RR; Chatterjee, S; Chen, H; Johnson, ML; Masurkar, PP; Sherer, JT | 1 |
Majidazar, R; Naseri, A; Rezazadeh-Gavgani, E; Sadigh-Eteghad, S | 1 |
Hamada, M; Murata, T | 1 |
Bu, K; Cheng, F; Han, W; Morris, R; Patel, D; Umeukeje, G; Zhu, T | 1 |
Lamba, D; Lozanov, V; Pesaresi, A; Tsekova, D; Vezenkov, L | 1 |
Liu, C; Liu, YM; Wang, LN | 1 |
Barić, D; Fodor, L; Horváth, O; Lasić, Z; Lovrić, MJ; Marinić, Ž; Milašinović, V; Mlakić, M; Molčanov, K; Odak, I; Škorić, I | 1 |
Catapano, MC; Chlebek, J; Hošťálková, A; Lomozová, Z; Macáková, K; Mladěnka, P; Parvin, MS | 1 |
Acar, OO; Deniz, FSS; Erdogan Orhan, I; Irmak, S; Luca, SV; Salmas, RE; Sen, A; Skalicka-Woźniak, K; Skiba, A; Tataringa, G; Turgut, GC; Zbancioc, AM | 1 |
Andersen, K; Grøntved, S; Lolk, A; Nielsen, RE; Valentin, JB | 1 |
Elhabak, M; Salama, AAA; Salama, AH | 1 |
Arellano-Martín, I; Bastida, J; Gómez-Murillo, P; Jiménez, C; Lisa-Molina, J; Rodríguez-Escobar, ML; Tallini, LR; Torras-Claveria, L; Viladomat, F | 1 |
Gao, F; Ji, WS; Lei, Y; Shan, LH; Wan, LX; Xiao, Y; Xu, JB; Zhang, Y; Zhou, XL | 1 |
Fan, F; Guo, B; Luo, W; Lv, J; Wang, C; Wang, Y; Yu, H; Zhai, J; Zhang, Z; Zhao, Y | 1 |
Blunden, G; Cahlíková, L; Vrabec, R | 1 |
Girgin, M; Isik, S; Kantarci-Carsibasi, N | 1 |
Achten, E; Beun, S; Clement, P; Moyaert, P | 1 |
Yamada, M | 1 |
Boada, M; Carnero-Pardo, C; Fortea, J; García-Ribas, G; Martínez-Lage, P; Olazarán, J; Sánchez-Juan, P; Viñuela, F | 1 |
Algharably, EEA; Bermpohl, F; Bittner, N; Brandl, EJ; Funk, CSM; Kreutz, R; Riemer, TG; Schmidt, A | 1 |
Armirotti, A; Bartolini, M; Basagni, F; Bedeschi, M; Bertorelli, R; Bertozzi, SM; Bottegoni, G; Cavalli, A; Lembo, V; Mellor, IR; Minarini, A; Ortega, JA; Rosini, M; Summa, M | 1 |
Han, W; Liao, Y; Shi, W; Wen, J; Zhang, G | 1 |
Antunes, CM; Burke, AJ; Carreiro, EP; Costa, AR; Ernesto, S; Pinto, F; Rodrigues, B | 1 |
Fleet, JL; Garg, AX; McArthur, E; Montero-Odasso, M; Patel, A; Weir, MA | 1 |
Emoto, MC; Fujii, HG; Hisahara, S; Iwahara, N; Kawamata, J; Manabe, T; Matsumura, A; Matsushita, T; Saito, T; Sato-Akaba, H; Shimohama, S; Suzuki, H; Suzuki, S; Yokokawa, K | 1 |
Ahmed, M; Aleya, L; Ashraf, GM; Barreto, GE; Begum, MM; Kabir, MT; Mathew, B; Rahman, MS; Thangapandiyan, S; Uddin, MS | 1 |
Correa-Basurto, J; Farfán-García, ED; Fragoso-Vázquez, MJ; García-Marín, ID; Gómez-López, M; Joseph, E; Miliar-García, Á; Rosales-Hernández, MC; Torres-Ramos, MA; Villalobos-Acosta, DMÁ | 1 |
Sharma, P; Shrivastava, SK; Tripathi, MK | 1 |
Chakkamparambil, B; Friedman, L; Grossberg, GT; Haake, A; Nguyen, K | 1 |
Honjo, Y; Ide, K; Takechi, H | 1 |
Gzielo, K; Krawczyk, M; Nikiforuk, A; Popik, P; Potasiewicz, A | 1 |
Abdel-Daim, MM; Aleya, L; Ashraf, GM; Bin-Jumah, MN; Jeandet, P; Kabir, MT; Mamun, AA; Mansouri, RA; Mathew, B; Uddin, MS | 1 |
Funayama, M; Kurose, S; Mimura, M; Mimura, Y; Tabuchi, H; Takata, T | 1 |
Awasthi, A; Corrie, L; Gulati, M; Kumar Singh, S; Vishwas, S | 1 |
Alexander, M; Ansell, D; Avillach, P; Celis-Morales, C; Collin, E; Egger, P; Gordon, MF; Grosdidier, S; Gungabissoon, U; James, G; Lawrance, M; Mosseveld, M; Mueller, A; Novak, G; Pasqua, A; Pedersen, L; Podhorna, J; Rijnbeek, P; Stewart, R; van der Lei, J; Zaremba-Pechmann, L | 1 |
Barthold, D; Drabo, EF; Ferido, P; Gray, SL; Joyce, G; Marcum, ZA; Zissimopoulos, J | 1 |
Ali, N; Arora, M; Ghai, R; Grover, P; Kapoor, G; Nagarajan, K | 1 |
Alsabbagh, MW; Huang, Y | 1 |
Atanasova, M; Atanasova, T; Doytchinova, I; Ivanov, S; Konstantinov, S; Lukarski, A; Philipova, I; Stavrakov, G; Zheleva, D; Zhivkova, ZD | 1 |
Koola, MM | 1 |
Amenta, F; Ben, DD; Buccioni, M; Lambertucci, C; Marucci, G; Volpini, R | 1 |
Bhanuprakash, K; Chitumalla, RK; Karthikraj, R; Nagaveni, V; Prabhakar, S; Vairamani, M | 1 |
Basar, MK; Baykal, AT; Coskun, J; Gurel, B; Kiris, I; Mroczek, T; Sahin, B | 1 |
Alamiri, B; Husain, K; Naguy, A | 1 |
Chmielewska, K; Dzierzbicka, K; Inkielewicz-Stepniak, I; Kowalski, S; Przybyłowska, M | 1 |
Ganguly, B; Ghosh, S; Jana, K; Wakchaure, PD | 1 |
Han, E; Kalisch Ellett, L; Lee, HJ; Lee, J; Roughead, EE | 1 |
Chang, X; Davies, JRT; Fraser, MD; Rowlands, GE; Vallin, HE | 1 |
Abdel-Daim, MM; Akhtar, MF; Albadrani, GM; Arya, A; Chahal, R; El-Seedi, HR; Kamel, M; Kaushik, D; Khalifa, SMA; Mittal, V; Rahman, MH; Rao, R; Saleem, A | 1 |
Fazal, SA; Haque, SE; Iqubal, A; Iqubal, MK; Pottoo, FH | 1 |
Halminen, O; Hörhammer, I; Linna, M; Mehtälä, J; Mikkola, T; Vesikansa, A; Virta, LJ; Ylisaukko-Oja, T | 1 |
Dunn, T; Howlett, SE; Rockwood, K; Stanley, J | 1 |
Bu, K; Cheng, F; Morris, R; Umeukeje, G | 1 |
Alexandrova, AV; Dragomanova, ST; Gavrilova, PT; Georgieva, AP; Handzhiyski, YS; Kalfin, RE; Kirilov, KT; Lazarova, MI; Papazova, MG; Tancheva, LP; Tsekova, DS; Tsvetanova, ER; Uzunova, DN; Vezenkov, LT | 1 |
Hoffman, D; Howlett, SE; Mitnitski, A; Rockwood, K; Schindler, R | 1 |
Avila, A; Lawler, E | 1 |
Boulouard, M; Dauphin, F; Freret, T; Hamidouche, K; Lecouflet, P; Lelong-Boulouard, V | 1 |
Bradley, J; Chan, P; Herrmann, N; Lanctôt, K; Mohammad, D | 1 |
Ribaudo, G; Zagotto, G; Zanforlin, E | 1 |
Ali, MR; Boutajangout, A; Mezei, M; Møller, SG; Sadoqi, M | 1 |
Kaushik, V; Mikobi, E; Raji, MA; Smith, ST | 1 |
Naharci, MI | 1 |
Chang, SY; Dong, L; Feng, M; Guo, X; Hügel, H; Hyde, AJ; Lu, C; May, BH; Xue, CC; Zhang, AL | 1 |
Iyo, M; Oda, Y; Okubo, T; Sato, K; Shirayama, Y; Takahashi, M; Yoshino, K | 1 |
Jiang, S; Lan, J; Pan, K; Yang, J; Yuan, L; Zhang, K; Zhang, Q; Zhang, T; Zhao, Y | 1 |
Atri, A; Ballard, C; Boneva, N; Cummings, JL; Frölich, L; Molinuevo, JL; Raket, LL; Tariot, PN; Windfeld, K | 1 |
Akilo, OD; Choonara, YE; du Toit, LC; Kumar, P; Pillay, V; Pradeep, P | 1 |
Agrawal, M; Alexander, A; Antimisiaris, SG; Chougule, MB; Saraf, S; Shoyele, SA | 1 |
Abe, K; Hishikawa, N; Huang, Y; Li, X; Liu, X; Morihara, R; Nakano, Y; Ohta, Y; Sato, K; Shang, J; Shi, X; Takemoto, M; Tian, F; Yamashita, T; Zhai, Y | 1 |
Fujita, Y; Haga, Y; Hanazawa, T; Kamijo, Y; Usui, K; Yoshizawa, T | 1 |
Mishra, DN; Singh, SK | 1 |
Hang, L; Jia, R; Li, J; Liang, J; Wang, Y; Wu, R; Xu, Y; Zhang, H | 1 |
Danchev, ND; Kostadinova, I; Mihaylova, R; Tsekova, DS; Vassilev, NG; Vezenkov, LT | 1 |
Lee, KW; Park, C; Rampogu, S; Son, M; Zeb, A | 1 |
Friedrich, L; Grisoni, F; Merk, D; Schneider, G | 1 |
Ameen, D; Michniak-Kohn, B | 1 |
de Andrade, JP; de Souza Borges, W; El Sohafy, SM; Shawky, E | 1 |
Chan, TY; Chan, WC; Chiu, J; Kng, CPL; Kong, HL; Lam, LCW; Lau, KH; Law, CB; Lin, KL; Ma, SL; Poon, TK; Tam, CCW; Tang, JHY; Tang, NLS; Wat, KHY | 1 |
Klaassen, ES; Klaassens, BL; Rombouts, SARB; van der Grond, J; van Gerven, JMA | 1 |
Eap, CB; Noetzli, M | 1 |
Cesario, A; Del Bufalo, A; Fini, M; Frustaci, A; Russo, P | 1 |
Adorni, F; Caltagirone, C; Di Santo, SG; Musicco, M; Prinelli, F | 1 |
Johnell, K; Sonde, L | 1 |
Brown, JN; Corbo, JM; Moss, JM | 1 |
Gard, PR; Isaac, M; Klugman, A; Richardson, C; Tabet, N | 1 |
Droogsma, E; Huinink, EJ; Schuur, T; van Asselt, DZ; van Steijn, JH | 1 |
Di, R; Lawton, MA; Long, C; Wang, H; Wang, Y; Wu, WH; Xin, L; Yamujala, R | 1 |
Abe, K | 1 |
Londos, E; Minthon, L; Paulsson, E; Wattmo, C | 1 |
Hattori, H | 1 |
Peters, KR | 1 |
Bozoglu, E; Celik, T; Isik, AT; Kaptan, K | 1 |
Birks, J; Craig, D | 2 |
Benitez-Cardoza, CG; Correa-Basurto, J; Hernández-Rodríguez, M; Resendiz-Albor, AA; Rosales-Hernández, MC | 1 |
Farlow, M; Ferris, SH | 1 |
Czarnocki, Z; Granica, S; Jarończyk, M; Kiss, AK; Maurin, JK; Mazurek, AP | 1 |
Kimura, Y; Kobayashi, T; Ohnishi, T; Okuri, Y; Saito, T; Sakiyama, Y; Sugiyama, N; Takahashi, M | 1 |
Cumbo, E; Ligori, LD | 1 |
Guo, T; Hu, R; Huang, H; Irwin, DM; Jin, L; Lei, Z; Li, H; Li, Z; Mao, Y; Niu, G; Song, R; Tan, H; Wang, R; Wang, X; Xu, W; Zhang, X; Zhang, Y; Zhou, N | 1 |
Shimohama, S | 3 |
Gaudig, M; Rettig, K; Richarz, U; Schauble, B | 1 |
Mullangi, R; Ponnayyan Sulochana, S; Sharma, K; Sukumaran, SK | 1 |
Ganesh, A; Ismail, Z; Jalal, H; Lau, R; Lysack, J | 1 |
Ahn, IS; Carroll, BJ; Hwang, TY; Kang, HS; Kim, DK; Ku, HM; Lee, Y; Myung, W; Song, J; Woo, SY | 1 |
Bhattacharya, S; Haertel, C; Maelicke, A; Montag, D | 1 |
Hartikainen, S; Koponen, M; Taipale, H; Tanskanen, A; Tiihonen, J; Tolppanen, AM | 1 |
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Babić, T; Mahović Lakusić, D; Petrovecki, M; Sertić, J; Stavljenić-Rukavina, A | 1 |
Geerts, H | 1 |
Arya, P; Butler, R; Warner, J | 2 |
Abramowski, D; De Deyn, PP; Staufenbiel, M; Van Dam, D | 1 |
Garre-Olmo, J; Gelada-Batlle, E; Hernández-Ferràndiz, M; Isern-Vila, A; López-Pousa, S; Lozano-Gallego, M; Majó-Llopart, J; Morante-Muñoz, V; Pericot-Nierga, I; Turon-Estrada, A; Vilalta-Franch, M | 1 |
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Ancoli-Israel, S; Cooke, JR; Corey-Bloom, J; Fiorentino, L; Harrison, T; Liu, L; Loredo, JS; Marler, M | 1 |
Blennow, K; de Leon, MJ; Zetterberg, H | 1 |
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Garre Olmo, J; López-Pousa, S; Pericot Nierga, I; Soler Cors, O; Turon Estrada, A; Vilalta Franch, J | 1 |
Verhey, FR | 1 |
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Huang, J; Marszalec, W; Narahashi, T; Toth, PT; Yeh, JZ; Zhao, X | 1 |
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Allen, G; Barnes, N; Boundy, K; Brodaty, H; Woodward, M | 1 |
Almkvist, O; Blomquist, G; Darreh-Shori, T; Eriksson, B; Grut, M; Kadir, A; Långström, B; Nordberg, A; Wall, A | 1 |
Amatniek, J; Jelic, V; Kershaw, P; Winblad, B | 1 |
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Robert Brashear, H; Spivey, JM | 1 |
Chu, LW; Chung, CP; Mok, W; Yik, PY | 1 |
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Campanozzi, MD; Casali, E; Martini, E; Neri, M; Neviani, F | 1 |
Ehlis, AC; Fallgatter, AJ; Herrmann, MJ; Plichta, MM; Richter, MM | 1 |
Almkvist, O; Blomquist, G; Darreh-Shori, T; Grut, M; Kadir, A; Långström, B; Nordberg, A; Ringheim, A; Strandberg, B; Wall, A | 1 |
Barnes, N; Boundy, K; Brodaty, H; Woodward, M | 1 |
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Candelise, L; Cantisani, TA; Celani, MG; Cusi, C; Incorvaia, B; Righetti, E | 1 |
De Raedt, R; Gorus, E; Lambert, M; Mets, T | 1 |
Forbes-McKay, KE; McGeown, WJ; Ries, M; Shanks, MF; Venneri, A; Waiter, GD | 1 |
Albuquerque, EX; Lopes, C; Njar, V; Pereira, EF; Purushottamachar, P; Schwarcz, R; Wu, HQ | 1 |
Aerssens, J; Alvidrez, J; Anand, R; Faison, WE; Farrer, LA; Jarvik, L; Manly, J; McRae, T; Mintzer, JE; Murphy, GM; Olin, JT; Regier, D; Sano, M; Schultz, SK | 1 |
Egert, S; Förstl, H; Wagenpfeil, S | 1 |
Basun, H; Cederholm, T; Eriksdotter-Jönhagen, M; Faxén-Irving, G; Freund-Levi, Y; Garlind, A; Grut, M; Palmblad, J; Vedin, I; Wahlund, LO | 1 |
Bonham, J; Connelly, PJ; Cousland, G; Prentice, NP | 1 |
Dai, D; Mitnitski, A; Rockwood, K | 1 |
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Baker, AS; Brandt, J; Lyketsos, CG; Mayer, LS; McNabney, M; Onyike, CU; Rosenblatt, A; Samus, QM | 1 |
Wong, VS | 1 |
Anghelescu, I; Heuser, I | 1 |
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Agelan, A; Del Valle, L; Woodruff-Pak, DS | 1 |
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Barkhof, F; Fox, NC; Korf, ES; Scheltens, P; van de Pol, LA; van der Flier, WM | 1 |
Lang, CJ | 1 |
Bär, KJ; Boettger, MK; Mentzel, HJ; Sauer, H; Seidler, N; Terborg, C | 1 |
Bajda, M; Malawska, B; Musiał, A | 1 |
Engel, J; Hager, K; Kenklies, M; McAfoose, J; Münch, G | 1 |
García, AG; López, MG; Marco-Contelles, J; Villarroya, M | 1 |
Bogetto, F; Marino, F; Montemagni, C; Perrone, D; Rocca, P | 1 |
Razay, G; Wilcock, GK | 1 |
do Carmo Carreiras, M; Marco, L | 1 |
Ames, D; Ashby, D; Birks, J; Kaduszkiewicz, H; van den Bussche, H; Zimmermann, T | 1 |
Landmark, K; Reikvam, A | 1 |
Choi, S; Jung, HY; Lee, CU; Suh, GH | 1 |
Brashear, R; Bullock, R; Erkinjuntti, T; Gauthier, S; Hammond, G; Kurz, A; Schwalen, S; Zhu, Y | 1 |
Brashear, HR; Feldman, H; Gauthier, S; Mayorga, AJ; Nye, JS; Scinto, L; Truyen, L; Wang, D; Wilcock, GK; Winblad, B | 1 |
Downey, D | 1 |
Cook, C; Fay, S; Rockwood, K | 1 |
Allali, G; Assal, F; Beauchet, O; Herrmann, FR; Kressig, RW | 1 |
Bahro, M; Berger, M; Gann, H; Hohagen, F; Lis, S; Riemann, D; Stadmüller, G | 1 |
Johansson, M; Nordberg, A | 1 |
Bores, GM; Camacho, F; Davis, L; Huger, FP; Kosley, RW; Mutlib, AE; Petko, W; Rush, DK; Selk, DE; Vargas, HM; Wolf, V | 1 |
Benfield, P; Fulton, B | 1 |
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Bastos, JK; Burandt, CL; McChesney, JD; Mikell, J; Moraes-Cerdeira, RM; Nanayakkara, D; Thurn, J | 1 |
MacGowan, SH; Scott, M; Wilcock, GK | 1 |
Brückner, A; Cvitkovich, B; Czollner, L; Fröhlich, J; Jordis, U; Kremser, L; Küenburg, B; Rizzi, A; Schuh, R | 1 |
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Peskind, ER; Raskind, MA; Wessel, T; Yuan, W | 1 |
Ding, C; Kershaw, P; Lilienfeld, S; Morris, JC; Solomon, PR; Tariot, PN | 1 |
Bucks, RS; Byrne, LM; Hughes, AO; Wilcock, GK; Wilson, PM | 1 |
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Maelicke, A | 3 |
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Cutler, NR; Frackiewicz, EJ; Sramek, JJ | 1 |
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Gaens, E; Lilienfeld, S; Wilcock, GK | 1 |
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Kashiwagi, Y; Kudo, T; Nakamura, Y; Nishikawa, T; Shinosaki, K; Takeda, M; Tanaka, T | 1 |
Andreasen, N; Blennow, K; Davidsson, P; Eriksson, B; Hesse, C; Minthon, L | 1 |
Albuquerque, EX; Fehrenbacher, A; Jostock, R; Ludwig, J; Maelicke, A; Samochocki, M; Zerlin, M | 1 |
Coyle, J; Kershaw, P | 1 |
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Dunbar, F; Rasmusen, L; Robillard, A; Yan, B | 1 |
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Farlow, MR; Ferris, SH; Kurz, AF; Maelicke, A; Morris, JC; Rasmusen, L; Wilkinson, D; Yan, B | 1 |
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Mintzer, J; Rockwood, K; Truyen, L; Wessel, T; Wilkinson, D | 1 |
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185 review(s) available for galantamine and Alzheimer Disease
Article | Year |
---|---|
Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018).
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Cholinesterases; Drug Design; Humans; Ligands; Neuroprotective Agents | 2019 |
Triazole derivatives as inhibitors of Alzheimer's disease: Current developments and structure-activity relationships.
Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Structure-Activity Relationship; Triazoles | 2019 |
The Efficacy and Safety of Alzheimer's Disease Therapies: An Updated Umbrella Review.
Topics: Activities of Daily Living; Alzheimer Disease; Amino Acids; Cholinesterase Inhibitors; Cognition; Donepezil; Galantamine; Ginkgo biloba; Humans; Nootropic Agents; Patient Safety; Plant Extracts; Rivastigmine | 2022 |
Comparative Efficacy and Acceptability of Cholinesterase Inhibitors and Memantine Based on Dosage in Patients with Vascular Cognitive Impairment: A Network Meta-analysis.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognitive Dysfunction; Donepezil; Galantamine; Humans; Indans; Memantine; Network Meta-Analysis; Nootropic Agents; Randomized Controlled Trials as Topic; Rivastigmine | 2022 |
Comparative safety and efficacy of cognitive enhancers for Alzheimer's dementia: a systematic review with individual patient data network meta-analysis.
Topics: Adult; Alzheimer Disease; Donepezil; Galantamine; Humans; Memantine; Network Meta-Analysis; Nootropic Agents; Rivastigmine | 2022 |
Pharmacotherapy of Alzheimer's disease: an overview of systematic reviews.
Topics: Alzheimer Disease; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cholinesterase Inhibitors; Donepezil; Galantamine; Glycogen Synthase Kinase 3; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Indans; Lithium; Melatonin; Memantine; Neurodegenerative Diseases; Rivastigmine; Systematic Reviews as Topic | 2022 |
Natural Alkaloids as Multi-Target Compounds towards Factors Implicated in Alzheimer's Disease.
Topics: Acetylcholinesterase; Aged; Alkaloids; Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans | 2023 |
Effect of Acetylcholinesterase Inhibitors on Cerebral Perfusion and Cognition: A Systematic Review.
Topics: Acetylcholinesterase; Alzheimer Disease; Cerebrovascular Circulation; Cholinesterase Inhibitors; Cognition; Dementia; Galantamine; Humans; Indans; Parkinson Disease; Perfusion; Phenylcarbamates; Piperidines; Rivastigmine | 2023 |
[Anti-Dementia Drugs (Anti-Alzheimer's Disease Drugs)].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Memantine; Receptors, N-Methyl-D-Aspartate; Rivastigmine | 2023 |
Psychiatric Adverse Events of Acetylcholinesterase Inhibitors in Alzheimer's Disease and Parkinson's Dementia: Systematic Review and Meta-Analysis.
Topics: Acetylcholinesterase; Alzheimer Disease; Anorexia; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Parkinson Disease; Phenylcarbamates; Randomized Controlled Trials as Topic; Rivastigmine; Sleep Initiation and Maintenance Disorders | 2023 |
Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Repositioning; Galantamine; Humans; Rivastigmine; Tacrine | 2019 |
An update on the utility and safety of cholinesterase inhibitors for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Rivastigmine | 2020 |
Combination Drug Therapy for the Management of Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Biomarkers; Cholinesterase Inhibitors; Clinical Trials as Topic; Disease Management; Disease Susceptibility; Dopamine Agents; Drug Therapy, Combination; Galantamine; Humans; Memantine | 2020 |
Current Strategies and Novel Drug Approaches for Alzheimer Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Mice; Phytotherapy; Plant Preparations; Rats; Rivastigmine | 2020 |
Comparative risk of cardiac arrhythmias associated with acetylcholinesterase inhibitors used in treatment of dementias - A narrative review.
Topics: Alzheimer Disease; Animals; Arrhythmias, Cardiac; Cholinesterase Inhibitors; Dementia; Donepezil; Galantamine; Humans; Rivastigmine | 2020 |
Galantamine-Memantine combination in the treatment of Alzheimer's disease and beyond.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Galantamine; Humans; Memantine; Nootropic Agents; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate | 2020 |
Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease.
Topics: Alzheimer Disease; Antioxidants; Cholinesterase Inhibitors; Donepezil; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Galantamine; Humans; Receptors, N-Methyl-D-Aspartate; Rivastigmine | 2021 |
Galantamine beyond Alzheimer's disease-a fact or artefact?
Topics: Alzheimer Disease; Artifacts; Cholinesterase Inhibitors; Galantamine; Humans | 2022 |
Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer's Disease Therapy.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Galantamine; Humans; Rivastigmine; Sesquiterpenes | 2021 |
Nutraceuticals and their Derived Nano-Formulations for the Prevention and Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Dietary Supplements; Donepezil; Galantamine; Humans | 2022 |
Alzheimer Disease: Monotherapy vs. Combination Therapy.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dopamine Agents; Drug Therapy, Combination; Galantamine; Humans; Indans; Memantine; Piperidines; Rivastigmine | 2017 |
Acetylcholinesterase inhibitors for treating dementia symptoms - a safety evaluation.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Dementia; Donepezil; Drug Interactions; Galantamine; Humans; Indans; Piperidines; Rivastigmine; Severity of Illness Index | 2017 |
An Overview of New Possible Treatments of Alzheimer's Disease, Based on Natural Products and Semi-Synthetic Compounds.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biological Products; Cholinesterase Inhibitors; Galantamine; Humans; Memantine; Receptors, Nicotinic; tau Proteins | 2017 |
Acetylcholinesterase Inhibitors: Beneficial Effects on Comorbidities in Patients With Alzheimer's Disease.
Topics: Alzheimer Disease; Cardiovascular Diseases; Cholinesterase Inhibitors; Comorbidity; Donepezil; Galantamine; Polypharmacy; Rivastigmine | 2018 |
Comparisons between traditional medicines and pharmacotherapies for Alzheimer disease: A systematic review and meta-analysis of cognitive outcomes.
Topics: Alzheimer Disease; Asia, Eastern; Cholinesterase Inhibitors; Cognition; Donepezil; Galantamine; Humans; Indans; Medicine, Traditional; Memantine; Nootropic Agents; Piperidines; Plant Extracts; Rivastigmine | 2018 |
Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs.
Topics: Administration, Intranasal; Alzheimer Disease; Animals; Biological Availability; Blood-Brain Barrier; Brain; Deferoxamine; Donepezil; Drug Carriers; Drug Liberation; Galantamine; Humans; Mucociliary Clearance; Nanoparticles; Nasal Mucosa; Nose; Olfactory Bulb; Risperidone; Tissue Distribution | 2018 |
Identification of the optimal cognitive drugs among Alzheimer's disease: a Bayesian meta-analytic review.
Topics: Alzheimer Disease; Antiparkinson Agents; Bayes Theorem; Cholinesterase Inhibitors; Cognition; Donepezil; Galantamine; Humans; Memantine; Neuroprotective Agents; Nootropic Agents; Rivastigmine | 2018 |
Pharmacodynamic, pharmacokinetic and pharmacogenetic aspects of drugs used in the treatment of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Excitatory Amino Acid Antagonists; Galantamine; Humans; Indans; Memantine; Pharmacogenetics; Phenylcarbamates; Piperidines; Receptors, N-Methyl-D-Aspartate; Rivastigmine | 2013 |
Multitarget drugs of plants origin acting on Alzheimer's disease.
Topics: Alkaloids; Alzheimer Disease; Animals; Biological Products; Cholinesterase Inhibitors; Crocus; Drug Discovery; Galantamine; Galanthus; Ginkgo biloba; Humans; Huperzia; Neuroprotective Agents; Physostigmine; Plant Extracts; Plants; Salvia; Sesquiterpenes | 2013 |
A meta-analysis of the efficacy of donepezil, rivastigmine, galantamine, and memantine in relation to severity of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Behavior; Cholinesterase Inhibitors; Cognition; Data Interpretation, Statistical; Disability Evaluation; Disease Progression; Donepezil; Female; Galantamine; Humans; Indans; Male; Memantine; Middle Aged; Neuroprotective Agents; Neuropsychological Tests; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Treatment Outcome | 2013 |
[Nicotinic acetylcholine receptor in Alzheimer's disease].
Topics: Alzheimer Disease; Galantamine; Humans; Receptors, Nicotinic; Synaptic Transmission; Thalamus; Treatment Outcome | 2013 |
[Effectiveness and limitation of newly approved drugs for Alzheimer's disease].
Topics: Alzheimer Disease; Clinical Trials as Topic; Galantamine; Humans; Japan; Memantine; Phenylcarbamates; Quality of Life; Rivastigmine | 2013 |
Galantamine for vascular cognitive impairment.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Dementia, Vascular; Galantamine; Humans; Nootropic Agents; Randomized Controlled Trials as Topic | 2006 |
Language impairment in Alzheimer's disease and benefits of acetylcholinesterase inhibitors.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Communication Disorders; Donepezil; Galantamine; Humans; Indans; Outcome Assessment, Health Care; Phenylcarbamates; Piperidines; Rivastigmine | 2013 |
Drugs for cognitive loss and dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Cholinesterase Inhibitors; Cognition Disorders; Dementia; Donepezil; Excitatory Amino Acid Antagonists; Galantamine; Humans; Indans; Memantine; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate; Rivastigmine | 2013 |
[Development of therapies for Alzheimer's disease based on cholinergic hypothesis-status quo and future directions].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinergic Neurons; Cholinesterase Inhibitors; Donepezil; Drug Discovery; Galantamine; Humans; Indans; Molecular Targeted Therapy; Neuroprostanes; Phenylcarbamates; Piperidines; Rivastigmine | 2013 |
Review of the validated HPLC and LC-MS/MS methods for determination of drugs used in clinical practice for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Donepezil; Galantamine; Humans; Indans; Neuroprotective Agents; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine; Tandem Mass Spectrometry | 2014 |
Cholinesterase-inhibitor Associated Mania: A Case Report and Literature Review.
Topics: Aged; Alzheimer Disease; Bipolar Disorder; Brain; Cholinesterase Inhibitors; Female; Galantamine; Humans; Positron-Emission Tomography | 2014 |
Efficacy and safety of donepezil, galantamine, rivastigmine, and memantine for the treatment of Alzheimer's disease: a systematic review and meta-analysis.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine | 2014 |
[Programs for continuing medical education: a session; 3. Dementia: diagnosis and therapy].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cholinesterase Inhibitors; Cognitive Dysfunction; Dementia; Disease Progression; Donepezil; Education, Medical, Continuing; Galantamine; Humans; Indans; Lewy Body Disease; Nootropic Agents; Peptide Fragments; Phenylcarbamates; Piperidines; Positron-Emission Tomography; Reference Standards; Rivastigmine; tau Proteins; Tomography, Emission-Computed, Single-Photon | 2014 |
Changes in gait variability with anti-dementia drugs: a systematic review and meta-analysis.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Gait; Galantamine; Humans; Indans; Memantine; Nootropic Agents; Piperidines | 2014 |
[Progress of dementia medicine: Special reference to Alzheimer's disease].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Brain; Cholinesterase Inhibitors; Donepezil; Drug Discovery; Galantamine; Humans; Indans; Magnetic Resonance Imaging; Memantine; Neurofibrillary Tangles; Nootropic Agents; Phenylcarbamates; Piperidines; Receptors, N-Methyl-D-Aspartate; Rivastigmine; Tomography, Emission-Computed, Single-Photon | 2014 |
Efficacy and safety of galantamine treatment for patients with Alzheimer's disease: a meta-analysis of randomized controlled trials.
Topics: Alzheimer Disease; Galantamine; Humans; Nootropic Agents; Randomized Controlled Trials as Topic | 2015 |
Current Practices in the Treatment of Alzheimer Disease: Where is the Evidence After the Phase III Trials?
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials, Phase III as Topic; Donepezil; Galantamine; Humans; Indans; Memantine; Nootropic Agents; Piperidines; Rivastigmine; Treatment Outcome | 2015 |
Effect of Genetic Polymorphisms (SNPs) in CHRNA7 Gene on Response to Acetylcholinesterase Inhibitors (AChEI) in Patients with Alzheimer's Disease.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Gene Expression Regulation; Humans; Indans; Male; Pharmacogenomic Variants; Piperidines; Polymorphism, Single Nucleotide; Treatment Outcome; Up-Regulation | 2017 |
Current Treatment Options for Alzheimer's Disease and Parkinson's Disease Dementia.
Topics: Alzheimer Disease; Animals; Antiparkinson Agents; Cholinesterase Inhibitors; Cognitive Behavioral Therapy; Dementia; Donepezil; Excitatory Amino Acid Antagonists; Exercise Therapy; Galantamine; Humans; Indans; Memantine; Parkinson Disease; Piperidines; Rivastigmine; Sleep Wake Disorders; Treatment Outcome | 2016 |
The comparative efficacy and safety of cholinesterase inhibitors in patients with mild-to-moderate Alzheimer's disease: a Bayesian network meta-analysis.
Topics: Aged; Alzheimer Disease; Bayes Theorem; Cholinesterase Inhibitors; Cognition; Donepezil; Female; Galantamine; Humans; Indans; Male; Middle Aged; Network Meta-Analysis; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine | 2016 |
Multitarget strategies in Alzheimer's disease: benefits and challenges on the road to therapeutics.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Donepezil; Drug Discovery; Galantamine; Humans; Indans; Molecular Targeted Therapy; Piperidines; Rivastigmine; Structure-Activity Relationship | 2016 |
Psychopharmacological Studies in Mice.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Dopamine; Drug Discovery; Environment; Female; Galantamine; Indans; Male; Mental Disorders; Mice; Molecular Targeted Therapy; Motivation; Piperidines; Psychopharmacology; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1D; Receptors, Dopamine D2; Research; Rivastigmine | 2016 |
Potential benefits of phytochemicals against Alzheimer's disease.
Topics: Alkaloids; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Galantamine; Ginkgo biloba; Humans; Melissa; Panax; Phytochemicals; Plant Extracts; Resveratrol; Rivastigmine; Salvia officinalis; Stilbenes; Terpenes | 2017 |
Analyses of mortality risk in patients with dementia treated with galantamine.
Topics: Age of Onset; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Female; Follow-Up Studies; Galantamine; Humans; Institutionalization; Male; National Institute of Neurological Disorders and Stroke (U.S.); Personality Inventory; Randomized Controlled Trials as Topic; Survival Analysis; Survivors; Time Factors; Treatment Outcome; United States | 2009 |
Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysis.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2008 |
[Relation between Pisa syndrome and choline esterase inhibitors in a cohort of Alzheimer's disease patients].
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Donepezil; Dystonia; Galantamine; Humans; Indans; Male; Piperidines; Syndrome | 2009 |
Importance of circadian rhythmicity in the cholinergic treatment of Alzheimer's disease: focus on galantamine*.
Topics: Acetylcholine; Activity Cycles; Aging; Alzheimer Disease; Cholinesterase Inhibitors; Female; Galantamine; Humans; Male; Memory; Sleep Stages | 2008 |
Intranasal administration of acetylcholinesterase inhibitors.
Topics: Administration, Intranasal; Alzheimer Disease; Animals; Blood-Brain Barrier; Central Nervous System Diseases; Cholinesterase Inhibitors; Galantamine; Humans | 2008 |
Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease.
Topics: Alkanes; Alzheimer Disease; Amides; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anisoles; Antioxidants; Aspartic Acid Endopeptidases; Attention; Choline; Drug Design; Ethylamines; Galantamine; Humans; Memory; Neurons; Phosphorylation; Plaque, Amyloid; Platelet Aggregation Inhibitors; tau Proteins | 2009 |
Galantamine for dementia in people with Down syndrome.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Down Syndrome; Galantamine; Humans | 2009 |
Discontinuing Alzheimer's disease drug therapy: why, when, and how.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Approval; Drug Monitoring; Excitatory Amino Acid Antagonists; Galantamine; Humans; Indans; Memantine; Neuroprotective Agents; Nursing Homes; Patient Selection; Phenylcarbamates; Piperidines; Prevalence; Receptors, N-Methyl-D-Aspartate; Rivastigmine; Severity of Illness Index; Treatment Failure; United States; Withholding Treatment | 2008 |
Treatment of Alzheimer's disease in the long-term-care setting.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dopamine Agents; Galantamine; Humans; Indans; Long-Term Care; Memantine; Phenylcarbamates; Piperidines; Rivastigmine | 2009 |
Are cholinesterase inhibitors effective in the management of the behavioral and psychological symptoms of dementia in Alzheimer's disease? A systematic review of randomized, placebo-controlled trials of donepezil, rivastigmine and galantamine.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Evidence-Based Medicine; Galantamine; Humans; Indans; Mental Disorders; Nootropic Agents; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Treatment Outcome | 2009 |
Safety and tolerability of donepezil, rivastigmine and galantamine for patients with Alzheimer's disease: systematic review of the 'real-world' evidence.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Evidence-Based Medicine; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine | 2009 |
[Anti-dementia drugs for dementia syndromes--just unkept promises?].
Topics: Alzheimer Disease; Clinical Trials as Topic; Dopamine Agents; Galantamine; Ginkgo biloba; Humans; Memantine; Meta-Analysis as Topic; Nootropic Agents; Phytotherapy; Plant Preparations; Syndrome | 2006 |
Galantamine for Alzheimer's disease.
Topics: Alzheimer Disease; Controlled Clinical Trials as Topic; Galantamine; Humans | 2010 |
A review of clinical pharmacokinetics and pharmacodynamics of galantamine, a reversible acetylcholinesterase inhibitor for the treatment of Alzheimer's disease, in healthy subjects and patients.
Topics: Administration, Oral; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Interactions; Galantamine; Half-Life; Humans; Protein Binding; Tissue Distribution | 2010 |
Galantamine-ER for the treatment of mild-to-moderate Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double Bind Interaction; Galantamine; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Severity of Illness Index | 2010 |
Galanthamine from Galanthus and other Amaryllidaceae--chemistry and biology based on traditional use.
Topics: Alzheimer Disease; Galantamine; Galanthus; Humans; Liliaceae; Molecular Structure; Phytotherapy | 2010 |
Current treatments for patients with Alzheimer disease.
Topics: Aggression; Alzheimer Disease; Behavior Therapy; Cholinesterase Inhibitors; Depression; Excitatory Amino Acid Antagonists; Galantamine; Health Status; Humans; Memantine; Neuroprotective Agents; Parasympathomimetics; Phenylcarbamates; Psychomotor Agitation; Psychotherapy; Psychotic Disorders; Rivastigmine; Time Factors; United States; United States Food and Drug Administration | 2010 |
Switching cholinesterase inhibitors in older adults with dementia.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Practice Guidelines as Topic; Rivastigmine; Treatment Outcome | 2011 |
[Daily functioning in dementia: pharmacological and non-pharmacological interventions demonstrate small effects on heterogeneous scales].
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Angiotensin-Converting Enzyme Inhibitors; Caregivers; Donepezil; Galantamine; Geriatric Assessment; Ginkgo biloba; Humans; Indans; Institutionalization; Memantine; Nootropic Agents; Phenylcarbamates; Phytotherapy; Piperidines; Plant Extracts; Randomized Controlled Trials as Topic; Rivastigmine | 2011 |
Galantamine and behavior in Alzheimer disease: analysis of four trials.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Caregivers; Double-Blind Method; Female; Galantamine; Humans; Male; Mental Disorders; Randomized Controlled Trials as Topic | 2011 |
Dementia.
Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Dementia; Galantamine; Humans; Memantine | 2010 |
An overview on natural cholinesterase inhibitors--a multi-targeted drug class--and their mass production.
Topics: Alkaloids; Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans; Huperzia; Liliaceae; Sesquiterpenes | 2011 |
Pharmacologists and Alzheimer disease therapy: to boldly go where no scientist has gone before.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Cholinesterase Inhibitors; Cognition; Donepezil; Galantamine; Humans; Indans; Memantine; Neurons; Oxidative Stress; Phenylcarbamates; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Rivastigmine | 2011 |
[Newly approved drugs for Alzheimer disease: effectiveness and limitation].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans; Memantine; Phenylcarbamates; Receptors, N-Methyl-D-Aspartate; Rivastigmine; Treatment Outcome | 2011 |
New drugs for Alzheimer's disease in Japan.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Discovery; Excitatory Amino Acid Antagonists; Galantamine; Humans; Indans; Japan; Memantine; Phenylcarbamates; Piperidines; Rivastigmine; Tacrine | 2011 |
[Pharmacological and clinical profiles of galantamine (Reminyl(®))].
Topics: Acetylcholine; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Galantamine; Humans; Learning; Memory; Neuroprotective Agents; Randomized Controlled Trials as Topic; Receptors, Nicotinic | 2011 |
Pharmacological treatment of Alzheimer disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Disease Progression; Donepezil; Galantamine; Humans; Indans; Memantine; Neuroprotective Agents; Neuropsychological Tests; Piperidines | 2011 |
New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs.
Topics: Alzheimer Disease; Clinical Trials as Topic; Donepezil; Drug Discovery; Excitatory Amino Acid Antagonists; Galantamine; Humans; Indans; Memantine; Neuroprotective Agents; Phenylcarbamates; Piperidines; Plaque, Amyloid; Rivastigmine; tau Proteins | 2012 |
Effective pharmacological management of Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Dementia; Disease Progression; Donepezil; Galantamine; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine; Tacrine; Time Factors; Treatment Outcome | 2011 |
The costs of Alzheimer's disease and the value of effective therapies.
Topics: Age Factors; Aging; Alzheimer Disease; Cholinesterase Inhibitors; Disease Progression; Donepezil; Galantamine; Health Care Costs; Health Expenditures; Humans; Indans; Medicare; Medicare Part D; Memantine; Piperidines; Psychometrics; United States | 2011 |
Symptomatic and nonamyloid/tau based pharmacologic treatment for Alzheimer disease.
Topics: Alkaloids; Alzheimer Disease; Amino Acids; Animals; Cholinesterase Inhibitors; Dietary Supplements; Disease Progression; Docosahexaenoic Acids; Donepezil; Drug Approval; Galantamine; Ginkgo biloba; Half-Life; History, 20th Century; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Phytotherapy; Piperidines; Psychotropic Drugs; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Rivastigmine; Sesquiterpenes; Vitamin B Complex; Vitamin E | 2012 |
Economic evaluation of treatment options in patients with Alzheimer's disease: a systematic review of cost-effectiveness analyses.
Topics: Alzheimer Disease; Cost-Benefit Analysis; Donepezil; Dopamine Agents; Drug Costs; Economics, Pharmaceutical; Galantamine; Humans; Indans; Memantine; Nootropic Agents; Piperidines; Quality-Adjusted Life Years | 2012 |
The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease (review of Technology Appraisal No. 111): a systematic review and economic model.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cost-Benefit Analysis; Donepezil; Dopamine Agents; Female; Galantamine; Humans; Indans; Male; Memantine; Middle Aged; Models, Economic; Phenylcarbamates; Piperidines; Rivastigmine; Technology Assessment, Biomedical | 2012 |
A novel subject synchronization clinical trial design for Alzheimer's disease.
Topics: Alzheimer Disease; Clinical Trials as Topic; Disease Progression; Galantamine; Humans; Nootropic Agents; Research Design | 2012 |
Cholinergic modulation by opioid receptor ligands: potential application to Alzheimer's disease.
Topics: Allosteric Regulation; Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans; Ligands; Opioid Peptides; Receptors, Nicotinic; Receptors, Opioid | 2013 |
Galantamine for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Galantamine; Humans; Multicenter Studies as Topic; Nootropic Agents; Randomized Controlled Trials as Topic | 2002 |
[New theory! Galantamine and nicotinic-cholinergic transmission].
Topics: Alzheimer Disease; Animals; Galantamine; Humans; Parasympathetic Nervous System; Receptors, Nicotinic; Synaptic Transmission | 2002 |
Galantamine--a novel cholinergic drug with a unique dual mode of action for the treatment of patients with Alzheimer's disease.
Topics: Alzheimer Disease; Angiotensin-Converting Enzyme Inhibitors; Caregivers; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition; Galantamine; Humans; Nootropic Agents; Psychiatric Status Rating Scales; Receptors, Nicotinic; Treatment Outcome | 2002 |
Medical treatment of Alzheimer's disease: past, present, and future.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Forecasting; Galantamine; Humans; Indans; Male; Phenylcarbamates; Piperidines; Prognosis; Rivastigmine; Severity of Illness Index; Tacrine; Treatment Outcome | 2002 |
Clinical and cost-effectiveness of donepezil, rivastigmine, and galantamine for Alzheimer's disease. A systematic review.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Cost of Illness; Cost-Benefit Analysis; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Quality of Life; Randomized Controlled Trials as Topic; Rivastigmine; Treatment Outcome | 2002 |
Treatment options: the latest evidence with galantamine (Reminyl).
Topics: Alzheimer Disease; Cerebrovascular Disorders; Dementia, Vascular; Endpoint Determination; Galantamine; Humans; Multicenter Studies as Topic; Nootropic Agents; Randomized Controlled Trials as Topic | 2002 |
Nicotinic receptor modulation: advantages for successful Alzheimer's disease therapy.
Topics: Aged; Alzheimer Disease; Galantamine; Humans; Nootropic Agents; Receptors, Nicotinic | 2002 |
A novel treatment for patients with Alzheimer's disease and with vascular dementia.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dementia, Vascular; Galantamine; Humans; Phytotherapy | 2002 |
Nicotinic cholinergic modulation: galantamine as a prototype.
Topics: Acetylcholine; Allosteric Regulation; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Galantamine; Humans; Learning; Ligands; Memory; Models, Animal; Models, Biological; Receptors, Nicotinic; Synaptic Transmission | 2002 |
[Anti-dementia drugs for Alzheimer disease in present and future].
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Carbamates; Cholinesterase Inhibitors; Donepezil; Drug Design; Galantamine; Humans; Indans; Memantine; Phenylcarbamates; Piperidines; Rivastigmine; Tacrine; tau Proteins | 2002 |
Plants with traditional uses and activities, relevant to the management of Alzheimer's disease and other cognitive disorders.
Topics: Alkaloids; Alzheimer Disease; Estrogens, Non-Steroidal; Galantamine; Humans; Isoflavones; Physostigmine; Phytoestrogens; Phytotherapy; Plant Extracts; Plant Preparations; Plants, Medicinal; Sesquiterpenes | 2003 |
Galantamine hydrobromide: an agent for Alzheimer's disease.
Topics: Allosteric Regulation; Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dose-Response Relationship, Drug; Formularies as Topic; Galantamine; Half-Life; Humans; Receptors, Nicotinic | 2003 |
A clinical overview of cholinesterase inhibitors in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Dose-Response Relationship, Drug; Galantamine; Humans; Indans; Neuropsychological Tests; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2002 |
Galantamine: a review of its use in Alzheimer's disease and vascular dementia.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Dementia, Vascular; Galantamine; Humans | 2003 |
Assessment of health economics in Alzheimer's disease (AHEAD): treatment with galantamine in the UK.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cost-Benefit Analysis; Drug Costs; Female; Galantamine; Humans; Male; Models, Econometric; Nootropic Agents; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Sensitivity and Specificity; United Kingdom | 2003 |
Current treatments for Alzheimer's disease: cholinesterase inhibitors.
Topics: Alzheimer Disease; Behavioral Symptoms; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition Disorders; Donepezil; Galantamine; Humans; Indans; Multicenter Studies as Topic; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2003 |
Dementia.
Topics: Alzheimer Disease; Anticonvulsants; Antipsychotic Agents; Carbamates; Donepezil; Galantamine; Ginkgo biloba; Humans; Indans; Nootropic Agents; Phenylcarbamates; Phosphatidylcholines; Physostigmine; Phytotherapy; Piperidines; Rivastigmine; Tacrine; Vitamin E | 2003 |
Update on Alzheimer drugs (galantamine).
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Galantamine; Humans | 2003 |
[Current therapy of patients with dementia].
Topics: Activities of Daily Living; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Controlled Clinical Trials as Topic; Dementia; Dementia, Vascular; Donepezil; Dopamine Agents; Female; Galantamine; Ginkgo biloba; Humans; Indans; Male; Memantine; Meta-Analysis as Topic; Multicenter Studies as Topic; Neuroprotective Agents; Nootropic Agents; Phenylcarbamates; Phytotherapy; Piperidines; Placebos; Plant Preparations; Prospective Studies; Rivastigmine; Tacrine; Time Factors | 2003 |
[Mechanisms of action of Alzheimer medications].
Topics: Alzheimer Disease; Animals; Carbamates; Cholinesterase Inhibitors; Cognition; Donepezil; Excitatory Amino Acid Antagonists; Galantamine; Humans; Indans; Memantine; Phenylcarbamates; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Rivastigmine | 2003 |
Clinical pharmacokinetics of galantamine.
Topics: Adult; Aged; Alzheimer Disease; Area Under Curve; Biological Availability; Cholinesterase Inhibitors; Clinical Trials as Topic; Drug Interactions; Female; Galantamine; Half-Life; Humans; Male; Middle Aged | 2003 |
Acetylcholinesterase inhibition in Alzheimer's Disease.
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Rivastigmine; Tacrine | 2004 |
[Galantamine (reminyl) in the treatment of Alzheimer's disease and vascular dementia].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dementia, Vascular; Drug Therapy, Combination; Galantamine; Humans; Treatment Outcome | 2003 |
Cholinesterase inhibitors used in the treatment of Alzheimer's disease: the relationship between pharmacological effects and clinical efficacy.
Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Animals; Behavioral Symptoms; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Drug Tolerance; Galantamine; Humans; Indans; Piperidines; Rats; Receptors, Nicotinic | 2004 |
Galanthamine from snowdrop--the development of a modern drug against Alzheimer's disease from local Caucasian knowledge.
Topics: Alzheimer Disease; Animals; Biological Availability; Cholinesterase Inhibitors; Clinical Trials as Topic; Galantamine; Galanthus; Georgia (Republic); Humans; Nootropic Agents; Treatment Outcome | 2004 |
[Drug therapy for aged patients with Alzheimer disease].
Topics: Aged; Alzheimer Disease; Alzheimer Vaccines; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cholinesterase Inhibitors; Donepezil; Drug Design; Endopeptidases; Enzyme Inhibitors; Galantamine; Humans; Indans; Piperidines; Severity of Illness Index | 2004 |
Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: implications for the intellectual disability population.
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Donepezil; Down Syndrome; Galantamine; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine | 2004 |
What are the treatment options for patients with severe Alzheimer's disease?
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Galantamine; Humans; Memantine; Phenylcarbamates; Receptors, N-Methyl-D-Aspartate; Rivastigmine; Severity of Illness Index; Treatment Outcome | 2004 |
Evidence-based pharmacotherapy of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinergic Agents; Cholinesterase Inhibitors; Cost-Benefit Analysis; Donepezil; Evidence-Based Medicine; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Research Design; Rivastigmine | 2004 |
Ginkgo biloba compared with cholinesterase inhibitors in the treatment of dementia: a review based on meta-analyses by the cochrane collaboration.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Ginkgo biloba; Humans; Indans; Multicenter Studies as Topic; Neuropsychological Tests; Nootropic Agents; Phenylcarbamates; Piperidines; Plant Extracts; Randomized Controlled Trials as Topic; Rivastigmine; Treatment Outcome | 2004 |
[Galantamine, an acetylcholinesterase inhibitor with various actions].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans | 2004 |
The benefits and risks associated with cholinesterase inhibitor therapy in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Animals; Basal Ganglia Diseases; Bradycardia; Central Nervous System Diseases; Cholinesterase Inhibitors; Clinical Trials as Topic; Comorbidity; Donepezil; Double-Blind Method; Drug Evaluation; Drug Interactions; Female; Galantamine; Gastrointestinal Diseases; Humans; Indans; Institutionalization; Longitudinal Studies; Male; Memantine; Meta-Analysis as Topic; Mice; Middle Aged; Nootropic Agents; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Single-Blind Method; Sleep Wake Disorders; Treatment Outcome | 2004 |
Galantamine for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Galantamine; Humans; Multicenter Studies as Topic; Nootropic Agents; Randomized Controlled Trials as Topic | 2004 |
Mechanisms of action of cognitive enhancers on neuroreceptors.
Topics: Alzheimer Disease; Animals; Donepezil; Galantamine; Humans; Indans; Nicotinic Agonists; Nootropic Agents; Piperidines; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2004 |
Indicators of neuroprotection with galantamine.
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Galantamine; Glutamic Acid; Humans; In Vitro Techniques; Indicators and Reagents; Models, Biological; Neuroprotective Agents; Treatment Outcome | 2005 |
Dementia.
Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Cognition; Dementia; Donepezil; Galantamine; Ginkgo biloba; Haloperidol; Humans; Indans; Memantine; Olanzapine; Phenylcarbamates; Physostigmine; Phytotherapy; Piperidines; Risperidone; Rivastigmine; Selegiline; Tacrine; Vitamin E | 2004 |
A comparison of donepezil and galantamine in the treatment of cognitive symptoms of Alzheimer's disease: a meta-analysis.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Galantamine; Humans; Indans; Male; Nootropic Agents; Piperidines; Treatment Outcome | 2005 |
Galantamine: use in Alzheimer's disease and related disorders.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Dementia, Vascular; Galantamine; Humans | 2004 |
Cholinesterase inhibitors in the treatment of dementia.
Topics: Acetylcholine; Acetylcholinesterase; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cost of Illness; Dementia; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Severity of Illness Index | 2005 |
Dementia.
Topics: Alzheimer Disease; Dementia; Donepezil; Galantamine; Ginkgo biloba; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Physostigmine; Phytotherapy; Piperidines; Rivastigmine; Tacrine | 2004 |
Reduction of caregiver burden in Alzheimer's disease by treatment with galantamine.
Topics: Aged; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Cost of Illness; Depression; Employment; Galantamine; Humans; Sleep Wake Disorders | 2005 |
Cognitive performance in patients with Alzheimer's disease receiving cholinesterase inhibitors for up to 5 years.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Donepezil; Galantamine; Humans; Indans; Long-Term Care; Phenylcarbamates; Piperidines; Rivastigmine | 2005 |
Pharmacologic treatment options in Alzheimer's disease: optimizing disease management.
Topics: Acetylcholine; Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Disease Management; Donepezil; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Galantamine; Glutamic Acid; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Piperidines; Receptors, N-Methyl-D-Aspartate; Rivastigmine; Severity of Illness Index; Tacrine; Treatment Outcome | 2005 |
[Pharmacological therapy in Alzheimer's disease. Current clinical practice in The Netherlands].
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Excitatory Amino Acid Antagonists; Galantamine; Humans; Memantine; Netherlands; Phenylcarbamates; Rivastigmine; Treatment Outcome | 2005 |
Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Treatment Outcome | 2005 |
Drug therapy of dementia in elderly patients. A review.
Topics: Aged; Alzheimer Disease; Dementia; Donepezil; Galantamine; Humans; Indans; Memantine; Neuroprotective Agents; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine | 2005 |
New anti-Alzheimer drugs from biodiversity: the role of the natural acetylcholinesterase inhibitors.
Topics: Acetylcholine; Alzheimer Disease; Biodiversity; Brain; Cholinesterase Inhibitors; Galantamine; Humans | 2005 |
Clinical trials in mild cognitive impairment: lessons for the future.
Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition Disorders; Donepezil; Galantamine; Humans; Indans; Lactones; Neuropsychological Tests; Phenylcarbamates; Piperidines; Rivastigmine; Severity of Illness Index; Sulfones; Vitamin E | 2006 |
A systematic review of the clinical effectiveness of donepezil, rivastigmine and galantamine on cognition, quality of life and adverse events in Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Psychiatric Status Rating Scales; Quality of Life; Randomized Controlled Trials as Topic; Rivastigmine; Treatment Outcome | 2006 |
Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Drug Delivery Systems; Drug Evaluation, Preclinical; Galantamine; Humans; Physostigmine; Protein Conformation | 2006 |
Circadian cholinergic rhythms: implications for cholinesterase inhibitor therapy.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Circadian Rhythm; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Rivastigmine; Sleep; Sleep, REM | 2006 |
Synthesis and pharmacology of galantamine.
Topics: Alzheimer Disease; Animals; Biomimetics; Cholinesterase Inhibitors; Galantamine; Humans; Models, Chemical; Nootropic Agents | 2006 |
The clinical and cost-effectiveness of donepezil, rivastigmine, galantamine and memantine for Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cost-Benefit Analysis; Donepezil; Dopamine Agents; Evidence-Based Medicine; Female; Galantamine; Humans; Indans; Male; Memantine; Neuroprotective Agents; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome; United Kingdom | 2006 |
Galantamine for Alzheimer's disease and mild cognitive impairment.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Double-Blind Method; Galantamine; Humans; Multicenter Studies as Topic; Nootropic Agents; Randomized Controlled Trials as Topic | 2006 |
Galantamine for vascular cognitive impairment.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Dementia, Vascular; Galantamine; Humans; Nootropic Agents; Randomized Controlled Trials as Topic | 2006 |
Cholinesterase inhibitors for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Nootropic Agents; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine | 2006 |
Dementia.
Topics: Alzheimer Disease; Benzodiazepines; Dementia; Donepezil; Galantamine; Ginkgo biloba; Humans; Indans; Memantine; Nootropic Agents; Olanzapine; Phenylcarbamates; Physostigmine; Phytotherapy; Piperidines; Rivastigmine; Selegiline; Tacrine | 2005 |
Current and emerging pharmacological treatment options for dementia.
Topics: Acetylcholine; Alzheimer Disease; Cholinesterase Inhibitors; Dementia; Donepezil; Galantamine; Humans; Indans; Lewy Body Disease; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Phenylcarbamates; Piperidines; Rivastigmine; Tacrine | 2006 |
Pharmacology of acetylcholinesterase inhibitors and N-methyl-D-aspartate receptors for combination therapy in the treatment of Alzheimer's disease.
Topics: Acetylcholine; Alzheimer Disease; Animals; Brain; Cholinesterase Inhibitors; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Galantamine; Glutamic Acid; Humans; Memantine; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2006 |
Rationale for combination therapy with galantamine and memantine in Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Drug Synergism; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Galantamine; Humans; Indans; Memantine; Nootropic Agents; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Severity of Illness Index | 2006 |
Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Male; Molecular Biology; Phenylcarbamates; Piperidines; Plaque, Amyloid; Positron-Emission Tomography; Randomized Controlled Trials as Topic; Rivastigmine; tau Proteins | 2006 |
[Mechanisms of neuroprotective effects of therapeutic acetylcholinesterase inhibitors used in treatment of Alzheimer's disease].
Topics: Alzheimer Disease; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Galantamine; Glutamates; Humans; Indans; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Piperidines; Rats; Receptors, Nicotinic; Tacrine | 2006 |
Towards a unifying hypothesis of Alzheimer's disease: cholinergic system linked to plaques, tangles and neuroinflammation.
Topics: Alkaloids; Alzheimer Disease; Amyloid; Cholinergic Fibers; Cholinesterase Inhibitors; Galantamine; Inflammation; Neurofibrillary Tangles; Plaque, Amyloid; Receptors, Nicotinic; Sesquiterpenes | 2006 |
[Pharmacotherapy for Alzheimer's disease].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Memantine; Neuroprotective Agents; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2006 |
[Medical treatment of Alzheimer's disease].
Topics: Activities of Daily Living; Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition; Dementia, Vascular; Disease Progression; Donepezil; Evidence-Based Medicine; Galantamine; Humans; Indans; Lewy Body Disease; Memantine; Nootropic Agents; Parkinson Disease; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Treatment Outcome | 2006 |
Galantamine extended release in Alzheimer's disease: profile report.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Clinical Trials as Topic; Delayed-Action Preparations; Galantamine; Humans; Nootropic Agents; Treatment Outcome | 2006 |
Treatment strategies for the behavioral symptoms of Alzheimer's disease: focus on early pharmacologic intervention.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Memantine; Mental Disorders; Piperidines; Time Factors | 2007 |
Potential ethnic modifiers in the assessment and treatment of Alzheimer's disease: challenges for the future.
Topics: Aged; Alzheimer Disease; Cross-Cultural Comparison; Donepezil; Ethnicity; Galantamine; Humans; Indans; Nootropic Agents; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Thiazoles; White People | 2007 |
[Cholinesterase inhibitors and Alzheimer's disease: meta-analysis of the verification of effectiveness, origin and bias of results in published studies].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Evidence-Based Medicine; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Publication Bias; Randomized Controlled Trials as Topic; Rivastigmine; Severity of Illness Index; Treatment Outcome | 2007 |
Beyond in vitro data: a review of in vivo evidence regarding the allosteric potentiating effect of galantamine on nicotinic acetylcholine receptors in Alzheimer's neuropathology.
Topics: Allosteric Regulation; Alzheimer Disease; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Galantamine; Humans; Nootropic Agents; Receptors, Nicotinic | 2007 |
[Acetylcholinesterase inhibitors for dementia--an update].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dementia; Donepezil; Galantamine; Humans; Indans; Lewy Body Disease; Multicenter Studies as Topic; Neuroprotective Agents; Nootropic Agents; Parkinson Disease; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Time Factors | 2007 |
Modelling disease progression in Alzheimer's disease: a review of modelling methods used for cost-effectiveness analysis.
Topics: Alzheimer Disease; Cost-Benefit Analysis; Disease Progression; Donepezil; Galantamine; Humans; Indans; Memantine; Models, Economic; Phenylcarbamates; Piperidines; Rivastigmine | 2007 |
[Are anti-dementia drugs worthwhile?].
Topics: Activities of Daily Living; Alzheimer Disease; Antiparkinson Agents; Cholinesterase Inhibitors; Cost-Benefit Analysis; Donepezil; Dopamine Agents; Drug Therapy, Combination; Economics, Medical; Excitatory Amino Acid Antagonists; Galantamine; Germany; Health Policy; Humans; Indans; Memantine; Meta-Analysis as Topic; Neuroprotective Agents; Nootropic Agents; Parasympathomimetics; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Time Factors | 2007 |
Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment.
Topics: Alkaloids; Alzheimer Disease; Binding Sites; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Indole Alkaloids; Isoquinolines; Phenylcarbamates; Physostigmine; Piperidines; Propidium; Rivastigmine; Steroids; Tacrine | 2007 |
An update on the pharmacology of galantamine.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Galantamine; Humans; Neuroprotective Agents; Nootropic Agents | 2007 |
Galantamine in Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Galantamine; Humans | 2008 |
Galanthamine, a natural product for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans | 2006 |
[Cholinesterase inhibitors in the treatment of dementia--are they useful in clinical practice?].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Dementia; Dementia, Vascular; Donepezil; Evidence-Based Medicine; Galantamine; Humans; Indans; Lewy Body Disease; Phenylcarbamates; Piperidines; Rivastigmine; Time Factors; Treatment Outcome | 2008 |
Pharmacologic management of Alzheimer disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Therapy, Combination; Galantamine; Humans; Indans; Memantine; N-Methylaspartate; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine | 2008 |
[Treatment of Alzheimer's disease: status quo and future considerations].
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Behavioral Symptoms; Choline; Cholinesterase Inhibitors; Cognition; Donepezil; Drug Design; Galantamine; Glutamic Acid; Humans; Indans; Phenylcarbamates; Piperidines; Receptors, N-Methyl-D-Aspartate; Risk Factors; Rivastigmine | 2008 |
Pharmacokinetic studies of cholinesterase inhibitors.
Topics: Adult; Aged; Alzheimer Disease; Female; Galantamine; Humans; Male; Middle Aged; Physostigmine; Tacrine | 1993 |
Galanthamine.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Clinical Trials as Topic; Galantamine; Humans | 1996 |
Allosteric modulation of nicotinic receptors as a treatment strategy for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinergic Agents; Galantamine; Humans; Receptors, Nicotinic; Synaptic Transmission | 2000 |
Galantamine: additional benefits to patients with Alzheimer's disease.
Topics: Alzheimer Disease; Clinical Trials as Topic; Cognition; Galantamine; Humans; Nicotinic Agonists | 2000 |
Review of the acetylcholinesterase inhibitor galanthamine.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Galantamine; Humans | 2000 |
Galantamine: a review of its use in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition; Disease Models, Animal; Galantamine; Humans | 2000 |
Cholinesterase inhibitors stabilize Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Rivastigmine; Tacrine; Trichlorfon | 2000 |
Allosteric sensitization of nicotinic receptors by galantamine, a new treatment strategy for Alzheimer's disease.
Topics: Allosteric Regulation; Allosteric Site; Alzheimer Disease; Animals; Cell Line; Cholinesterase Inhibitors; Galantamine; Humans; Mice; Neurons; Nootropic Agents; Patch-Clamp Techniques; Receptors, Nicotinic | 2001 |
Galantamine, a cholinesterase inhibitor that allosterically modulates nicotinic receptors: effects on the course of Alzheimer's disease.
Topics: Aged; Allosteric Regulation; Allosteric Site; Alzheimer Disease; Brain; Cholinesterase Inhibitors; Clinical Trials, Phase III as Topic; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Galantamine; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Receptors, Nicotinic | 2001 |
Clinical and cost-effectiveness of donepezil, rivastigmine and galantamine for Alzheimer's disease: a rapid and systematic review.
Topics: Alzheimer Disease; Carbamates; Cost-Benefit Analysis; Donepezil; Galantamine; Humans; Indans; Neuroprotective Agents; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine | 2001 |
Galantamine for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Galantamine; Humans; Nootropic Agents; Randomized Controlled Trials as Topic | 2001 |
The pharmacological rationale for treating vascular dementia with galantamine (Reminyl).
Topics: Acetylcholine; Alzheimer Disease; Cholinesterase Inhibitors; Dementia, Vascular; Galantamine; Humans; Nootropic Agents; Receptors, Cholinergic; Receptors, Nicotinic | 2001 |
Use of cholinesterase inhibitors for treatment of Alzheimer disease.
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Rivastigmine; Tacrine | 2001 |
[Anticholinesterase agents in Alzheimer's disease].
Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbamates; Cholinesterase Inhibitors; Diagnosis, Differential; Disease Progression; Donepezil; Drug Therapy, Combination; Estrogen Replacement Therapy; Galantamine; Humans; Indans; Nootropic Agents; Phenylcarbamates; Piperidines; Prognosis; Rivastigmine; Treatment Outcome | 2001 |
Galantamine for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Galantamine; Humans; Nootropic Agents; Randomized Controlled Trials as Topic | 2001 |
Galantamine: a new alzheimer drug with a past life.
Topics: Alzheimer Disease; Galantamine; Humans; Nootropic Agents | 2001 |
Current status and new developments with galantamine in the treatment of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Clinical Trials, Phase III as Topic; Galantamine; Humans | 2001 |
[Perspectives for drug treatment in Alzheimer's disease].
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Donepezil; Drug Therapy, Combination; Galantamine; Humans; Indans; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine; Tacrine | 2001 |
[Latest therapies for treating dementia].
Topics: Adult; Aged; Alzheimer Disease; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clinical Trials as Topic; Cognition; Cohort Studies; Controlled Clinical Trials as Topic; Dementia, Vascular; Donepezil; Female; Fluoxetine; Galantamine; Haloperidol; Hormone Replacement Therapy; Humans; Hydroxychloroquine; Indans; Middle Aged; Nootropic Agents; Piperidines; Placebos; Practice Guidelines as Topic; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Time Factors; Trazodone | 2002 |
Understanding and managing behavioural symptoms in Alzheimer's disease and related dementias: focus on rivastigmine.
Topics: Acetylcholine; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Cognitive Behavioral Therapy; Disease Progression; Donepezil; Galantamine; Humans; Indans; Neuroprotective Agents; Phenylcarbamates; Physostigmine; Piperidines; Rivastigmine; Tacrine; Time Factors; Treatment Outcome | 2002 |
108 trial(s) available for galantamine and Alzheimer Disease
Article | Year |
---|---|
Acute response to cholinergic challenge predicts long-term response to galantamine treatment in patients with Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Galantamine; Humans; Nootropic Agents; Treatment Outcome | 2022 |
Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials.
Topics: Accidental Falls; Aged; Aged, 80 and over; Alzheimer Disease; Benzylamines; Cholinesterase Inhibitors; Cognition; Donepezil; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Galantamine; Humans; Indans; Indoles; Male; Middle Aged; Piperidines; Rivastigmine; Serotonin Antagonists; Treatment Failure | 2018 |
Cholinergic and serotonergic modulation of resting state functional brain connectivity in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebellum; Cerebral Cortex; Cholinesterase Inhibitors; Citalopram; Connectome; Cross-Over Studies; Double-Blind Method; Female; Galantamine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Net; Selective Serotonin Reuptake Inhibitors; Thalamus | 2019 |
The prediction of response to galantamine treatment in patients with mild to moderate Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Galantamine; Humans; Predictive Value of Tests; Retrospective Studies; Treatment Outcome | 2014 |
Differential effects of current specific treatments on behavioral and psychological symptoms in patients with Alzheimer's disease: a 12-month, randomized, open-label trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Behavioral Symptoms; Cholinesterase Inhibitors; Dementia; Donepezil; Excitatory Amino Acid Antagonists; Female; Galantamine; Humans; Indans; Longitudinal Studies; Male; Memantine; Mental Disorders; Phenylcarbamates; Piperidines; Psychiatric Status Rating Scales; Rivastigmine | 2014 |
Galantamine treatment in outpatients with mild Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Cognition; Female; Follow-Up Studies; Galantamine; Humans; Male; Nootropic Agents; Outpatients; Prospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome | 2014 |
Cognitive subdomain responses to galantamine in Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Executive Function; Female; Galantamine; Humans; Male; Memory Disorders; Neuropsychological Tests; Severity of Illness Index; Treatment Outcome | 2014 |
Retrospective study on the benefits of combined Memantine and cholinEsterase inhibitor treatMent in AGEd Patients affected with Alzheimer's Disease: the MEMAGE study.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Comorbidity; Donepezil; Female; Galantamine; Humans; Indans; Italy; Male; Memantine; Middle Aged; Nootropic Agents; Phenylcarbamates; Piperidines; Psychiatric Status Rating Scales; Retrospective Studies; Rivastigmine; Time Factors; Treatment Outcome | 2014 |
Effects of galantamine and galantamine combined with nimodipine on cognitive speed and quality of life in mixed dementia: a 24-week, randomized, placebo-controlled exploratory trial (the REMIX study).
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition; Dementia; Double-Blind Method; Drug Therapy, Combination; Female; Galantamine; Humans; Male; Neuropsychological Tests; Nimodipine; Quality of Life; Surveys and Questionnaires; Time Factors; Treatment Outcome; Vasodilator Agents | 2014 |
Galantamine versus risperidone for agitation in people with dementia: a randomized, twelve-week, single-center study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Dementia; Dementia, Vascular; Female; Galantamine; Humans; Male; Nootropic Agents; Psychomotor Agitation; Risperidone; Treatment Outcome | 2014 |
Functional connectivity increase in the default-mode network of patients with Alzheimer's disease after long-term treatment with Galantamine.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Brain Mapping; Cholinesterase Inhibitors; Female; Galantamine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Models, Neurological; Neuropsychological Tests; Oxygen; Principal Component Analysis; Psychiatric Status Rating Scales; Rest; Time Factors | 2016 |
Comprehensive effects of galantamine and cilostazol combination therapy on patients with Alzheimer's disease with asymptomatic lacunar infarction.
Topics: Aged; Alzheimer Disease; Asymptomatic Diseases; Brain; Cholinesterase Inhibitors; Cilostazol; Cognition; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Galantamine; Humans; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Psychiatric Status Rating Scales; Retrospective Studies; Stroke, Lacunar; Tetrazoles; Time Factors; Treatment Outcome | 2017 |
Effect of concomitant use of memantine on mortality and efficacy outcomes of galantamine-treated patients with Alzheimer's disease: post-hoc analysis of a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Disability Evaluation; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Galantamine; Humans; Longitudinal Studies; Male; Memantine; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Treatment Outcome | 2016 |
Effect of galantamine on attention in patients with Alzheimer's disease combined with cerebrovascular disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Attention; Cerebrovascular Disorders; Cholinesterase Inhibitors; Female; Galantamine; Humans; Male; Middle Aged; Surveys and Questionnaires; Treatment Outcome | 2017 |
Galantamine Response Associates with Agitation and the Prefrontal Cortex in Patients with Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Behavioral Symptoms; Brain; Caregivers; Cost of Illness; Female; Galantamine; Humans; Male; Mental Status and Dementia Tests; Psychotropic Drugs; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2017 |
Effects of Risperidone and Galantamine Treatment on Alzheimer's Disease Biomarker Levels in Cerebrospinal Fluid.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cholinesterase Inhibitors; Follow-Up Studies; Galantamine; Humans; Peptide Fragments; Phosphorylation; Psychotropic Drugs; Risperidone; tau Proteins; Treatment Outcome | 2017 |
Adherence and Tolerability of Alzheimer's Disease Medications: A Pragmatic Randomized Trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Costs; Drug-Related Side Effects and Adverse Reactions; Ethnicity; Female; Galantamine; Humans; Indans; Indiana; Male; Medication Adherence; Piperidines; Rivastigmine | 2017 |
One-week dose titration of extended release galantamine in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Galantamine; Humans; Male; Middle Aged | 2008 |
Safety and efficacy of galantamine (Reminyl) in severe Alzheimer's disease (the SERAD study): a randomised, placebo-controlled, double-blind trial.
Topics: Activities of Daily Living; Aged, 80 and over; Alzheimer Disease; Cognition; Double-Blind Method; Electrocardiography; Female; Galantamine; Humans; Male; Neuropsychological Tests; Nootropic Agents | 2009 |
Different cholinesterase inhibitor effects on CSF cholinesterases in Alzheimer patients.
Topics: Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Galantamine; Humans; Indans; Male; Middle Aged; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2009 |
Misplacing objects in mild to moderate Alzheimer's disease: a descriptive analysis from the VISTA clinical trial.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Caregivers; Data Interpretation, Statistical; Emotions; Female; Galantamine; Humans; Male; Memory; Neuropsychological Tests; Nootropic Agents; Treatment Outcome; Videotape Recording | 2009 |
Carotid intima-media thickness as a predictor of response to cholinesterase inhibitors in Alzheimer's disease: an open-label trial.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Atherosclerosis; Carotid Artery Diseases; Cholinesterase Inhibitors; Female; Galantamine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Predictive Value of Tests; Psychiatric Status Rating Scales; Regression Analysis; Ultrasonography | 2009 |
Decreased activation along the dorsal visual pathway after a 3-month treatment with galantamine in mild Alzheimer disease: a functional magnetic resonance imaging study.
Topics: Aged; Alzheimer Disease; Brain Mapping; Cholinesterase Inhibitors; Cognition Disorders; Face; Follow-Up Studies; Galantamine; Humans; Magnetic Resonance Imaging; Neuropsychological Tests; Recognition, Psychology; Visual Perception | 2009 |
The ADAS-cog and clinically meaningful change in the VISTA clinical trial of galantamine for Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Cognition Disorders; Double-Blind Method; Female; Galantamine; Humans; Male; Neuropsychological Tests; Nootropic Agents; Severity of Illness Index | 2010 |
Safety and tolerability of galantamine in possible Alzheimer's disease with or without cerebrovascular disease and vascular dementia in Thai patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cohort Studies; Female; Galantamine; Humans; Male; Middle Aged; Thailand | 2009 |
Trospium and cognition in patients with late onset Alzheimer disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Benzilates; Cholinesterase Inhibitors; Cognition; Depression; Drug Interactions; Drug Therapy, Combination; Female; Galantamine; Geriatric Assessment; Humans; Male; Mental Health; Muscarinic Antagonists; Nocturia; Nortropanes; Patient Satisfaction; Urinary Incontinence | 2009 |
[Galantamine (reminyl) in the treatment of severe Alzheimer's disease].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Galantamine; Humans; Male; Middle Aged; Severity of Illness Index; Treatment Outcome | 2009 |
Increased glutamate in the hippocampus after galantamine treatment for Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain Mapping; Choline; Cholinesterase Inhibitors; Creatine; Female; Galantamine; Glutamic Acid; Hippocampus; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Mental Status Schedule; Neuropsychological Tests; Regression Analysis | 2010 |
Cortical oxygen supply during postural hypotension is further decreased in Alzheimer's disease, but unrelated to cholinesterase-inhibitor use.
Topics: Aged; Alzheimer Disease; Cerebrovascular Circulation; Cholinesterase Inhibitors; Female; Galantamine; Humans; Hypotension, Orthostatic; Male; Microcirculation; Middle Cerebral Artery; Oxygen; Oxyhemoglobins; Spectroscopy, Near-Infrared; Ultrasonography, Doppler, Transcranial | 2010 |
[Oral galantamine versus rivastigmine transdermal patch: a descriptive study at a memory clinic in The Netherlands].
Topics: Administration, Cutaneous; Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Female; Galantamine; Humans; Male; Memory; Middle Aged; Phenylcarbamates; Rivastigmine; Treatment Outcome | 2010 |
Long-term effects of galantamine treatment on brain functional activities as measured by PET in Alzheimer's disease patients.
Topics: Aged; Alzheimer Disease; Brain; Cerebrovascular Circulation; Double-Blind Method; Female; Galantamine; Humans; Male; Middle Aged; Positron-Emission Tomography; Time Factors; Treatment Outcome | 2011 |
Galantamine (Reminyl) once daily outcome and satisfaction survey (RODOS) in mild to moderate Alzheimer's disease: a study in a real life population.
Topics: Aged; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Cognition; Delayed-Action Preparations; Donepezil; Female; Galantamine; Humans; Indans; Male; Patient Satisfaction; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2011 |
Evaluation of the effects of galantamine on cardiac function in elderly patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood Pressure; Bradycardia; Cholinesterase Inhibitors; Delayed-Action Preparations; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Female; Galantamine; Heart Block; Humans; Male; Nootropic Agents; Patient Dropouts | 2010 |
Cessation versus continuation of galantamine treatment after 12 months of therapy in patients with Alzheimer's disease: a randomized, double blind, placebo controlled withdrawal trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Double-Blind Method; Female; Galantamine; Humans; Male; Middle Aged; Neuropsychological Tests; Nootropic Agents; Treatment Outcome; Withholding Treatment | 2011 |
Effects of galantamine in Alzheimer's disease: double-blind withdrawal studies evaluating sustained versus interrupted treatment.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Female; Galantamine; Humans; Male; Treatment Outcome | 2011 |
Longitudinal changes of fractional anisotropy in Alzheimer's disease patients treated with galantamine: a 12-month randomized, placebo-controlled, double-blinded study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anisotropy; Biological Availability; Cholinesterase Inhibitors; Corpus Callosum; Diffusion Tensor Imaging; Double-Blind Method; Female; Galantamine; Gyrus Cinguli; Humans; Male; Nerve Fibers, Myelinated; Neuropsychological Tests; Outcome Assessment, Health Care | 2012 |
Long-term effects of galantamine on cognitive function in Alzheimer's disease: a large-scale international retrospective study.
Topics: Aged; Alzheimer Disease; Brief Psychiatric Rating Scale; Cognition; Cognition Disorders; Female; Follow-Up Studies; Galantamine; Humans; Internationality; Male; Retrospective Studies; Time Factors; Treatment Outcome | 2011 |
Two galantamine titration regimens in patients switched from donepezil.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Galantamine; Humans; Indans; Male; Middle Aged; Neuropsychological Tests; Piperidines; Treatment Outcome | 2012 |
A combination of galantamine and memantine modifies cognitive function in subjects with amnestic MCI.
Topics: Aged; Alzheimer Disease; Amnesia; Cholinesterase Inhibitors; Cognition; Cognitive Dysfunction; Cohort Studies; Dementia; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Early Termination of Clinical Trials; Female; Galantamine; Germany; Humans; Male; Memantine; Middle Aged; Nootropic Agents; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate | 2012 |
Functional response to cholinesterase inhibitor therapy in a naturalistic Alzheimer's disease cohort.
Topics: Activities of Daily Living; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Disabled Persons; Donepezil; Female; Galantamine; Humans; Indans; Linear Models; Male; Middle Aged; Neuropsychological Tests; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2012 |
Efficacy of galantamine in probable vascular dementia and Alzheimer's disease combined with cerebrovascular disease: a randomized trial.
Topics: Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition; Dementia, Vascular; Double-Blind Method; Galantamine; Humans; Treatment Outcome | 2002 |
Efficacy of galantamine in probable vascular dementia and Alzheimer's disease combined with cerebrovascular disease: a randomized trial.
Topics: Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Dementia, Vascular; Double-Blind Method; Galantamine; Humans; Nausea; Psychiatric Status Rating Scales; Severity of Illness Index; Treatment Outcome; Vomiting | 2002 |
Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Donepezil; Enzyme-Linked Immunosorbent Assay; Galantamine; Humans; Indans; Peptide Fragments; Phenylcarbamates; Phosphorylation; Piperidines; Rivastigmine; tau Proteins | 2002 |
Galantamine provides sustained benefits in patients with 'advanced moderate' Alzheimer's disease for at least 12 months.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Galantamine; Humans; Psychiatric Status Rating Scales; Severity of Illness Index; Time Factors; Treatment Outcome | 2003 |
The efficacy of galantamine in the treatment of Alzheimer's disease: comparison of patients previously treated with acetylcholinesterase inhibitors to patients with no prior exposure.
Topics: Aged; Alzheimer Disease; Analysis of Variance; Cholinesterase Inhibitors; Cognition; Double-Blind Method; Female; Galantamine; Humans; Male; Nootropic Agents; Parasympathomimetics; Polypharmacy; Treatment Outcome | 2003 |
An open-label extension trial of galantamine in patients with probable vascular dementia and mixed dementia.
Topics: Aged; Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition; Dementia, Vascular; Double-Blind Method; Female; Galantamine; Humans; Male | 2003 |
Economic evaluation of galantamine in the treatment of mild to moderate Alzheimer's disease in the United States.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Cost Savings; Dose-Response Relationship, Drug; Female; Galantamine; Health Care Costs; Humans; Male; Models, Economic; Nursing Homes; Patient Care; Randomized Controlled Trials as Topic; Time Factors; United States | 2003 |
A long-term comparison of galantamine and donepezil in the treatment of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cognition; Donepezil; Drug Administration Schedule; Female; Galantamine; Humans; Indans; Male; Mental Status Schedule; Piperidines; Time; Treatment Outcome | 2003 |
Sleep-related outcomes in persons with mild to moderate Alzheimer disease in a placebo-controlled trial of galantamine.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Double-Blind Method; Drug Administration Schedule; Female; Galantamine; Humans; Male; Prevalence; Severity of Illness Index; Sleep Wake Disorders | 2003 |
Galantamine in the treatment of cognitive decline in patients with vascular dementia or Alzheimer's disease with cerebrovascular disease.
Topics: Aged; Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition; Dementia, Vascular; Double-Blind Method; Female; Galantamine; Humans; Male; Psychiatric Status Rating Scales; Treatment Outcome | 2003 |
The effects of galantamine treatment on caregiver time in Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Female; Galantamine; Humans; Interpersonal Relations; Male; Middle Aged; Nootropic Agents; Time Factors; Treatment Outcome | 2003 |
Management of patients with Alzheimer's disease plus cerebrovascular disease: 12-month treatment with galantamine.
Topics: Aged; Alzheimer Disease; Dementia, Vascular; Female; Galantamine; Humans; Male; Nootropic Agents; Quality of Life; Treatment Outcome | 2004 |
Long-term safety and cognitive effects of galantamine in the treatment of probable vascular dementia or Alzheimer's disease with cerebrovascular disease.
Topics: Aged; Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition; Dementia, Vascular; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Galantamine; Humans; Male; Neuropsychological Tests | 2003 |
A multinational, randomised, 12-week study comparing the effects of donepezil and galantamine in patients with mild to moderate Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Attitude of Health Personnel; Attitude to Health; Caregivers; Cholinesterase Inhibitors; Cognition; Donepezil; Female; Galantamine; Humans; Indans; Male; Middle Aged; Nootropic Agents; Piperidines; Treatment Outcome | 2004 |
The cognitive benefits of galantamine are sustained for at least 36 months: a long-term extension trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Disease Progression; Double-Blind Method; Electrocardiography; Female; Galantamine; Humans; Long-Term Care; Male; Neuropsychological Tests; Psychiatric Status Rating Scales | 2004 |
Reduction of behavioral disturbances and caregiver distress by galantamine in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Behavioral Symptoms; Caregivers; Cholinesterase Inhibitors; Cost of Illness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Galantamine; Humans; Male; Mental Status Schedule; Neuropsychological Tests; Psychometrics | 2004 |
The clinical efficacy and safety of galantamine in the treatment of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cognition; Double-Blind Method; Female; Galantamine; Humans; Male; Nootropic Agents | 2004 |
Effectiveness and safety of cholinesterase inhibitors in elderly subjects with Alzheimer's disease: a "real world" study.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Female; Galantamine; Humans; Indans; Male; Neuropsychological Tests; Phenylcarbamates; Piperidines; Rivastigmine; Severity of Illness Index | 2004 |
Galantamine maintains ability to perform activities of daily living in patients with Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Analysis of Variance; Cholinesterase Inhibitors; Double-Blind Method; Female; Galantamine; Humans; Male; Nootropic Agents; Treatment Outcome; United States | 2004 |
Effects of galantamine on attention and memory in Alzheimer's disease measured by computerized neuropsychological tests: results of the Brazilian Multi-Center Galantamine Study (GAL-BRA-01).
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Attention; Brazil; Cholinesterase Inhibitors; Diagnosis, Computer-Assisted; Female; Galantamine; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Prospective Studies | 2004 |
Long-term efficacy and safety of galantamine in patients with mild-to-moderate Alzheimer's disease: multicenter trial.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Female; Galantamine; Humans; Long-Term Care; Male | 2004 |
An open-label, comparative study of rivastigmine, donepezil and galantamine in a real-world setting.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Humans; Indans; Male; Mental Status Schedule; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2004 |
Effects of galantamine in patients with mild Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Female; Galantamine; Humans; Male; Treatment Outcome | 2004 |
Challenging the cholinergic system in mild cognitive impairment: a pharmacological fMRI study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; Cholinergic Fibers; Cognition Disorders; Dominance, Cerebral; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Galantamine; Gyrus Cinguli; Hippocampus; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Long-Term Care; Magnetic Resonance Imaging; Male; Mental Recall; Middle Aged; Neuropsychological Tests; Pattern Recognition, Visual | 2004 |
A prospective, double-blind, community-controlled comparison of three doses of galantamine in the treatment of mild to moderate Alzheimer's disease in a Korean population.
Topics: Aged; Alzheimer Disease; Asian People; Disability Evaluation; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Galantamine; Humans; Korea; Male; Neuropsychological Tests; Nootropic Agents; Prospective Studies; Treatment Outcome | 2004 |
ApoE genotyping and response to galanthamine in Alzheimer's disease--a real life retrospective study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Apolipoproteins E; Cholinesterase Inhibitors; Female; Galantamine; Homozygote; Humans; Male; Middle Aged; Patient Selection; Retrospective Studies | 2004 |
Differential efficacy of treatment with acetylcholinesterase inhibitors in patients with mild and moderate Alzheimer's disease over a 6-month period.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Administration Schedule; Female; Galantamine; Humans; Indans; Male; Middle Aged; Neuropsychological Tests; Phenylcarbamates; Piperidines; Prospective Studies; Retrospective Studies; Rivastigmine; Severity of Illness Index; Time Factors | 2005 |
Cholinesterase inhibitor affects the amyloid precursor protein isoforms in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cholinesterase Inhibitors; Female; Galantamine; Humans; Isomerism; Male; Middle Aged | 2005 |
[Cost-effectiveness of galantamine in a german context].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Cost-Benefit Analysis; Disease Progression; Drug Costs; Female; Galantamine; Germany; Humans; Male; Markov Chains; Mental Status Schedule; National Health Programs; Nootropic Agents; Psychometrics; Quality-Adjusted Life Years; Statistics as Topic; Survival Rate | 2005 |
Switching from donepezil to galantamine: a double-blind study of two wash-out periods.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Double-Blind Method; Drug Administration Schedule; Female; Galantamine; Humans; Indans; Male; Piperidines | 2005 |
Metabolic patterns associated with the clinical response to galantamine therapy: a fludeoxyglucose f 18 positron emission tomographic study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Behavioral Symptoms; Brain; Brain Mapping; Cognition; Female; Fluorodeoxyglucose F18; Functional Laterality; Galantamine; Humans; Imaging, Three-Dimensional; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Nootropic Agents; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Treatment Outcome | 2005 |
Pharmacokinetic simulation for switching from galantamine immediate-release to extended-release formulation.
Topics: Administration, Oral; Adsorption; Alzheimer Disease; Biological Availability; Capsules; Cholinesterase Inhibitors; Delayed-Action Preparations; Galantamine; Humans; Models, Theoretical; Tablets | 2005 |
A cohort study of effectiveness of acetylcholinesterase inhibitors in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Cohort Studies; Donepezil; Female; Follow-Up Studies; Galantamine; Humans; Indans; Italy; Male; Middle Aged; Phenylcarbamates; Piperidines; Rivastigmine; Time Factors; Treatment Outcome | 2005 |
Galantamine treatment of problematic behavior in Alzheimer disease: post-hoc analysis of pooled data from three large trials.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Delusions; Double-Blind Method; Female; Galantamine; Humans; Male; Mental Disorders; Psychomotor Agitation; Treatment Outcome | 2005 |
Galantamine prolonged-release formulation in the treatment of mild to moderate Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Behavior; Cholinesterase Inhibitors; Delayed-Action Preparations; Double-Blind Method; Endpoint Determination; Female; Galantamine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales | 2005 |
Do MCI criteria in drug trials accurately identify subjects with predementia Alzheimer's disease?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Cognition Disorders; Cohort Studies; Female; Follow-Up Studies; Galantamine; Humans; Lactones; Male; Memory Disorders; Middle Aged; Neuroprotective Agents; Neuropsychological Tests; Piracetam; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Sulfones | 2005 |
Effect of the apolipoprotein E epsilon4 allele on the efficacy and tolerability of galantamine in the treatment of Alzheimer's disease.
Topics: Aged; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Delusions; Double-Blind Method; Galantamine; Hallucinations; Humans; Neuropsychological Tests; Nootropic Agents; Prospective Studies; Treatment Outcome | 2006 |
Attainment of treatment goals by people with Alzheimer's disease receiving galantamine: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Cognition Disorders; Female; Galantamine; Humans; Male; Placebos; Severity of Illness Index; Treatment Outcome | 2006 |
Efficacy study of galantamine in possible Alzheimer's disease with or without cerebrovascular disease and vascular dementia in Thai patients: a slow-titration regimen.
Topics: Aged; Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Dementia, Vascular; Drug Administration Schedule; Female; Galantamine; Humans; Male; Nootropic Agents; Treatment Outcome | 2006 |
Post hoc comparison of daily rates of nausea and vomiting with once- and twice-daily galantamine from a double-blind, placebo-controlled, parallel-group, 6-month study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antiemetics; Cholinesterase Inhibitors; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Galantamine; Humans; Male; Middle Aged; Nausea; Vomiting | 2006 |
Acetylcholinesterase inhibitors and sleep architecture in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Humans; Indans; Male; Middle Aged; Phenylcarbamates; Piperidines; Polysomnography; Rivastigmine; Sleep Stages; Sleep Wake Disorders | 2006 |
A naturalistic study of galantamine for Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Cognition; Female; Galantamine; Humans; Interview, Psychological; Male; Middle Aged; Neuropsychological Tests; Nootropic Agents; Prospective Studies; Treatment Outcome | 2006 |
Inhibition of acetylcholinesterase in CSF versus brain assessed by 11C-PMP PET in AD patients treated with galantamine.
Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Galantamine; Humans; Immunoprecipitation; Male; Middle Aged; Neuropsychological Tests; Phenylcarbamates; Positron-Emission Tomography; Radiopharmaceuticals | 2008 |
A 2-year open-label study of galantamine therapy in Chinese Alzheimer's disease patients in Hong Kong.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; China; Cholinesterase Inhibitors; Cognition; Female; Follow-Up Studies; Galantamine; Hong Kong; Humans; Male; Neuropsychological Tests; Nootropic Agents; Severity of Illness Index; Time Factors; Treatment Outcome | 2007 |
Brain activation in elderly people with and without dementia: Influences of gender and medication.
Topics: Aged; Alzheimer Disease; Arousal; Brain; Female; Galantamine; Hemoglobin A; Hemoglobins; Humans; Male; Mental Recall; Neuropsychological Tests; Nootropic Agents; Oxyhemoglobins; Prefrontal Cortex; Reference Values; Sex Factors; Spectroscopy, Near-Infrared; Thinking; Verbal Behavior; Vocabulary | 2007 |
PET imaging of the in vivo brain acetylcholinesterase activity and nicotine binding in galantamine-treated patients with AD.
Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Brain; Cholinesterase Inhibitors; Double-Blind Method; Enzyme Activation; Female; Galantamine; Humans; Male; Nicotine; Placebo Effect; Positron-Emission Tomography; Protein Binding; Tissue Distribution; Treatment Outcome | 2008 |
Naturalistic treatment of Alzheimer's disease with galantamine: 12-month follow-up from the NATURE study.
Topics: Alzheimer Disease; Female; Follow-Up Studies; Galantamine; Humans; Male; Mental Status Schedule; Nootropic Agents; Observation; Prospective Studies; Time Factors | 2007 |
Effect of galantamine on verbal repetition in AD: a secondary analysis of the VISTA trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Communication Disorders; Diagnostic Imaging; Double-Blind Method; Female; Follow-Up Studies; Galantamine; Humans; Male; Neuropsychological Tests; Severity of Illness Index; Treatment Outcome; Video Recording | 2007 |
The influence of galantamine on reaction time, attention processes, and performance variability in elderly Alzheimer patients.
Topics: Aged, 80 and over; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Attention; Benzodiazepines; Decision Making; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Galantamine; Humans; Male; Mandelic Acids; Movement; Parasympatholytics; Patient Dropouts; Prospective Studies; Reaction Time; Selective Serotonin Reuptake Inhibitors; Task Performance and Analysis; Trazodone | 2007 |
Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptoms.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Analysis of Variance; Apolipoproteins E; Cholinesterase Inhibitors; Depression; Dietary Supplements; Donepezil; Double-Blind Method; Fatty Acids, Omega-3; Female; Galantamine; Genotype; Humans; Indans; Male; Phenylcarbamates; Piperidines; Psychiatric Status Rating Scales; Rivastigmine; Statistics, Nonparametric; Treatment Outcome | 2008 |
A randomised double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Analysis of Variance; Chi-Square Distribution; Cholinesterase Inhibitors; Dietary Supplements; Donepezil; Double-Blind Method; Female; Folic Acid; Folic Acid Deficiency; Galantamine; Homocysteine; Humans; Indans; Male; Mental Status Schedule; Phenylcarbamates; Piperidines; Placebos; Rivastigmine; Treatment Outcome; Vitamin B Complex; Vitamins | 2008 |
Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment.
Topics: Age Factors; Aged; Alzheimer Disease; Apolipoprotein E4; Atrophy; Biomarkers; Cholinesterase Inhibitors; Cognition Disorders; Cohort Studies; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Galantamine; Genetic Predisposition to Disease; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Predictive Value of Tests; Prognosis | 2007 |
Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis.
Topics: Aged; Alzheimer Disease; Antioxidants; Cholinesterase Inhibitors; Cognition Disorders; Disease Progression; Donepezil; Female; Follow-Up Studies; Galantamine; Humans; Indans; Long-Term Care; Male; Mental Status Schedule; Middle Aged; Oxidative Stress; Piperidines; Thioctic Acid | 2007 |
Economic and clinical benefits of galantamine in the treatment of mild to moderate Alzheimer's disease in a Korean population: a 52-week prospective study.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cost of Illness; Double-Blind Method; Female; Galantamine; Health Care Costs; Humans; Male; Prospective Studies | 2008 |
Galantamine treatment in Alzheimer's disease with cerebrovascular disease: responder analyses from a randomized, controlled trial (GAL-INT-6).
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Cerebrovascular Disorders; Cognition; Cross-Over Studies; Disease Progression; Double-Blind Method; Female; Galantamine; Humans; Male; Nootropic Agents; Psychomotor Performance; Risk Assessment | 2008 |
Safety and efficacy of galantamine in subjects with mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Cohort Studies; Double-Blind Method; Female; Galantamine; Humans; Male; Middle Aged; Retrospective Studies | 2008 |
Decreased initiation of usual activities in people with mild-to-moderate Alzheimer's disease: a descriptive analysis from the VISTA clinical trial.
Topics: Activities of Daily Living; Affective Symptoms; Aged; Aged, 80 and over; Alzheimer Disease; Attitude of Health Personnel; Attitude to Health; Caregivers; Cholinesterase Inhibitors; Female; Galantamine; Health Status; Humans; Leisure Activities; Male; Middle Aged; Psychiatric Status Rating Scales; Qualitative Research; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome; Videotape Recording | 2008 |
Galantamine improves gait performance in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Attention; Cholinesterase Inhibitors; Female; Gait; Galantamine; Humans; Male; Mental Status Schedule; Neurologic Examination; Neuropsychological Tests; Nootropic Agents | 2008 |
Cholinergic neurotransmission, REM sleep and depression.
Topics: Adolescent; Adult; Aged; Alzheimer Disease; Brain Stem; Cholinergic Agonists; Cholinergic Fibers; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Galantamine; Humans; Male; Mental Disorders; Middle Aged; Parasympathomimetics; Physostigmine; Polysomnography; Reaction Time; Receptors, Muscarinic; Sleep Stages; Sleep Wake Disorders; Sleep, REM; Succinimides; Synaptic Transmission; Tacrine | 1994 |
Effect of gender and apolipoprotein E genotype on response to anticholinesterase therapy in Alzheimer's disease.
Topics: Alzheimer Disease; Apolipoproteins E; Cholinesterase Inhibitors; Double-Blind Method; Female; Galantamine; Genotype; Humans; Male; Sex Characteristics; Tacrine; Time Factors | 1998 |
Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group.
Topics: Aged; Alzheimer Disease; Apolipoproteins E; Body Weight; Cholinesterase Inhibitors; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Galantamine; Humans; Male; Neuropsychological Tests; Treatment Outcome | 2000 |
A 5-month, randomized, placebo-controlled trial of galantamine in AD. The Galantamine USA-10 Study Group.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Behavioral Symptoms; Body Weight; Cholinesterase Inhibitors; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Female; Galantamine; Humans; Male; Neuropsychological Tests; Severity of Illness Index; Treatment Outcome | 2000 |
Efficacy and safety of galantamine in patients with mild to moderate Alzheimer's disease: multicentre randomised controlled trial. Galantamine International-1 Study Group.
Topics: Aged; Alzheimer Disease; Double-Blind Method; Europe; Female; Galantamine; Humans; Male; Nootropic Agents; Treatment Outcome | 2000 |
Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease.
Topics: Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Biomarkers; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Female; Galantamine; Humans; Indans; Male; Middle Aged; Piperidines | 2001 |
Galantamine: a randomized, double-blind, dose comparison in patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Galantamine; Humans; Male; Mental Status Schedule; Treatment Outcome | 2001 |
Effects of a flexible galantamine dose in Alzheimer's disease: a randomised, controlled trial.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Disability Evaluation; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Galantamine; Humans; Male; Neuropsychological Tests; Receptors, Nicotinic; Severity of Illness Index; Synaptic Transmission; Time Factors; Treatment Outcome | 2001 |
Efficacy of galantamine in probable vascular dementia and Alzheimer's disease combined with cerebrovascular disease: a randomised trial.
Topics: Aged; Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition; Dementia, Vascular; Double-Blind Method; Female; Galantamine; Humans; Male; Treatment Outcome | 2002 |
Galanthamine treatment in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Galantamine; Humans; Male; Middle Aged; Neuropsychological Tests; Pilot Projects | 1991 |
345 other study(ies) available for galantamine and Alzheimer Disease
Article | Year |
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Synthesis and evaluation of 5-amino-5,6,7,8-tetrahydroquinolinones as potential agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Aminoquinolines; Animals; Cholinesterase Inhibitors; Dementia; Drug Evaluation; Male; Mice; Rats; Scopolamine; Sesquiterpenes; Structure-Activity Relationship | 1995 |
Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Cholinesterase Inhibitors; Drug Design; Galantamine; Galanthus; Hydrogen Bonding; Molecular Structure; Stereoisomerism; Torpedo; X-Ray Diffraction | 1999 |
Three-dimensional structure of a complex of galanthamine (Nivalin) with acetylcholinesterase from Torpedo californica: implications for the design of new anti-Alzheimer drugs.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Cholinesterase Inhibitors; Crystallization; Crystallography, X-Ray; Cyclohexanes; Cyclohexenes; Drug Design; Galantamine; Models, Molecular; Nootropic Agents; Protein Conformation; Structure-Activity Relationship; Torpedo | 2001 |
Isoquinoline derivatives as potential acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Animals; Benzylisoquinolines; Binding Sites; Cholinesterase Inhibitors; Colorimetry; Humans; Isoquinolines; Structure-Activity Relationship | 2006 |
6-Hydroxy- and 6-methoxy-beta-carbolines as acetyl- and butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Carbolines; Cholinesterase Inhibitors; Galantamine; Humans; Inhibitory Concentration 50; Phenylcarbamates; Physostigmine; Rivastigmine; Serotonin | 2006 |
Methyl 2-(2-(4-formylphenoxy)acetamido)-2-substituted acetate derivatives: a new class of acetylcholinesterase inhibitors.
Topics: Acetates; Alzheimer Disease; Benzaldehydes; Cholinesterase Inhibitors; Humans; Inhibitory Concentration 50; Structure-Activity Relationship | 2007 |
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Butyrylcholinesterase; Cell Line; Cholinesterase Inhibitors; Humans; Ligands; Models, Molecular; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Polyamines; Protein Binding; Quinones; Reactive Oxygen Species; Structure-Activity Relationship; Substrate Specificity | 2007 |
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
Topics: Alzheimer Disease; Butyrylcholinesterase; Carbolines; Cholinesterase Inhibitors; Excitatory Amino Acid Antagonists; Humans; Inhibitory Concentration 50; Memantine; Neurodegenerative Diseases; Receptors, N-Methyl-D-Aspartate | 2010 |
Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Calcium; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytotoxins; Electron Transport Chain Complex Proteins; Electrophorus; Glucose; Hippocampus; Humans; Isomerism; Models, Molecular; Naphthyridines; Neuroprotective Agents; Okadaic Acid; Oligomycins; Oxygen; Peptide Fragments; Protein Binding; Protein Phosphatase 2; Rats; Rotenone; Structure-Activity Relationship | 2010 |
Nantenine as an acetylcholinesterase inhibitor: SAR, enzyme kinetics and molecular modeling investigations.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Aporphines; Catalytic Domain; Cholinesterase Inhibitors; Electrophorus; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Protein Structure, Tertiary; Spectrophotometry; Structure-Activity Relationship | 2011 |
Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyri
Topics: Acetylcholinesterase; Alzheimer Disease; Aminopyridines; Animals; Butyrylcholinesterase; Cell Line, Tumor; Cholinergic Agents; Cholinesterase Inhibitors; Electrophorus; Horses; Humans; Models, Molecular; Neurons; Neuroprotective Agents; Nitriles; Pyridines; Vascular Diseases | 2010 |
(+)-Arisugacin A--computational evidence of a dual binding site covalent inhibitor of acetylcholinesterase.
Topics: Alzheimer Disease; Binding Sites; Cholinesterase Inhibitors; Computer Simulation; Inhibitory Concentration 50; Models, Biological; Models, Molecular; Molecular Structure; Pyrans | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Crystallography, X-Ray; Dose-Response Relationship, Drug; Erythrocytes; Models, Molecular; Molecular Structure; Quinolizidines; Stereoisomerism; Structure-Activity Relationship | 2011 |
Benzenediol-berberine hybrids: multifunctional agents for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Berberine; Cholinesterase Inhibitors; Coumaric Acids; Humans; Hydroquinones; Melatonin; Mice; Models, Molecular; Molecular Structure; Peptide Fragments; Structure-Activity Relationship | 2011 |
Design, synthesis, and evaluation of indanone derivatives as acetylcholinesterase inhibitors and metal-chelating agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Chelating Agents; Cholinesterase Inhibitors; Drug Design; Humans; Indans; Kinetics; Metals; Pyridines; Structure-Activity Relationship | 2012 |
Development and evaluation of multifunctional agents for potential treatment of Alzheimer's disease: application to a pyrimidine-2,4-diamine template.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Diamines; Humans; Models, Molecular; Molecular Structure; Pyrimidines; Retinoblastoma; Structure-Activity Relationship | 2012 |
Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cell Proliferation; Cerebral Cortex; Cholinesterase Inhibitors; Computer Simulation; Drug Combinations; Drug Design; Feasibility Studies; Galantamine; Humans; Male; Memantine; Neuroblastoma; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2012 |
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Coumarins; Horses; Humans | 2013 |
Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Binding Sites; Catalytic Domain; Cholinesterase Inhibitors; Drug Design; Flavonoids; Humans; Kinetics; Molecular Docking Simulation; Peptide Fragments; Structure-Activity Relationship | 2013 |
Design, synthesis and biological activity of multifunctional α,β-unsaturated carbonyl scaffolds for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Binding Sites; Catalytic Domain; Chalcones; Cholinesterase Inhibitors; Coumarins; Drug Design; Humans; Molecular Docking Simulation; Structure-Activity Relationship | 2013 |
Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Coumarins; Dose-Response Relationship, Drug; Drug Design; Electrophorus; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Tacrine | 2013 |
Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavonoids; Free Radical Scavengers; Humans; Mice; Neuroblastoma; Organometallic Compounds; Oxidation-Reduction; Peptide Fragments; Picrates; Structure-Activity Relationship; Tacrine | 2013 |
Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Butyrylcholinesterase; Carbazoles; Cell Line; Cholinesterase Inhibitors; Electrophorus; Humans; Male; Memory Disorders; Mice; Molecular Docking Simulation; Oxidative Stress; Tacrine | 2014 |
Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cotinine; Humans; Neurons; Neuroprotective Agents; Nicotine; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate | 2014 |
Design, synthesis and biological evaluation of D-ring opened galantamine analogs as multifunctional anti-Alzheimer agents.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Drug Design; Female; Galantamine; Magnetic Resonance Spectroscopy; Microscopy, Atomic Force; Nitric Oxide; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization | 2014 |
Design, synthesis and biological evaluation of benzylisoquinoline derivatives as multifunctional agents against Alzheimer's disease.
Topics: Alzheimer Disease; Benzylisoquinolines; Cholinesterase Inhibitors; Drug Design; Humans; Models, Molecular; Structure-Activity Relationship | 2014 |
Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Carbolines; Cell Line; Chelating Agents; Cholinesterase Inhibitors; Drug Design; Electrophorus; Horses; Humans; Molecular Docking Simulation; Protein Aggregation, Pathological; Tacrine | 2014 |
Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors.
Topics: Alzheimer Disease; Animals; Benzofurans; Cholinesterase Inhibitors; Male; Mice | 2015 |
Sulfonamides as multifunctional agents for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Donepezil; Free Radical Scavengers; Humans; Indans; Molecular Dynamics Simulation; Piperidines; Protein Binding; Sulfonamides | 2015 |
In Vitro Inhibitory Effects of 8-O-Demethylmaritidine and Undulatine on Acetylcholinesterase and Their Predicted Penetration across the Blood-Brain Barrier.
Topics: Acetylcholinesterase; Alzheimer Disease; Amaryllidaceae Alkaloids; Biological Transport; Blood-Brain Barrier; Cholinesterase Inhibitors; Humans; In Vitro Techniques; Molecular Structure | 2015 |
Potential of aryl-urea-benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzofurans; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Dynamics Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles; Torpedo; Urea | 2015 |
Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Binding Sites; Butyrylcholinesterase; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Computer Simulation; Coumarins; Drug Evaluation, Preclinical; Galantamine; Humans; Hydrogen Peroxide; Male; Mice, Inbred BALB C; Models, Molecular; Neuroprotective Agents; Neurotoxicity Syndromes | 2016 |
Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease.
Topics: Alzheimer Disease; Binding Sites; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; HT29 Cells; Humans; Molecular Structure; Phenols; Structure-Activity Relationship | 2016 |
Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzopyrans; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation | 2016 |
Synthesis and screening of triazolopyrimidine scaffold as multi-functional agents for Alzheimer's disease therapies.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Butyrylcholinesterase; Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Drug Evaluation, Preclinical; Humans; Kinetics; Molecular Docking Simulation; Peptide Fragments; Protein Aggregates; Protein Conformation; Pyrimidines | 2016 |
New cholinesterase inhibitors for Alzheimer's disease: Structure Activity Studies (SARs) and molecular docking of isoquinolone and azepanone derivatives.
Topics: Alzheimer Disease; Azepines; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2016 |
Structure-activity relationship studies of benzyl-, phenethyl-, and pyridyl-substituted tetrahydroacridin-9-amines as multitargeting agents to treat Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amines; Amyloid beta-Peptides; Binding Sites; Butyrylcholinesterase; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Drug Design; Humans; Inhibitory Concentration 50; Kinetics; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship | 2016 |
Avarol derivatives as competitive AChE inhibitors, non hepatotoxic and neuroprotective agents for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophorus; Hep G2 Cells; Humans; Liver; Molecular Docking Simulation; Neuroprotective Agents; Protein Conformation; Sesquiterpenes | 2016 |
Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening.
Topics: Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2016 |
New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Antineoplastic Agents; Butyrylcholinesterase; Catalytic Domain; Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Drug Design; Humans; Hydrazones; Molecular Docking Simulation; Piperidines | 2016 |
Synthesis and evaluation of dihydropyrimidinone-derived selenoesters as multi-targeted directed compounds against Alzheimer's disease.
Topics: Alzheimer Disease; Antioxidants; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Esters; Humans; Molecular Structure; Organoselenium Compounds; Pyrimidinones; Structure-Activity Relationship | 2016 |
New azepino[4,3-b]indole derivatives as nanomolar selective inhibitors of human butyrylcholinesterase showing protective effects against NMDA-induced neurotoxicity.
Topics: Alzheimer Disease; Azepines; Butyrylcholinesterase; Cell Line, Tumor; Cholinesterase Inhibitors; Humans; Indoles; N-Methylaspartate; Neurons; Neuroprotective Agents | 2017 |
Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cell Line, Tumor; Cholinesterase Inhibitors; Donepezil; Esters; Humans; Indans; Inhibitory Concentration 50; Molecular Docking Simulation; Molecular Targeted Therapy; Piperidines; Protein Conformation; Structure-Activity Relationship | 2017 |
Design and synthesis of new piperidone grafted acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Cell Line, Tumor; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Piperidones; Structure-Activity Relationship | 2017 |
Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer's disease agents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Carbolines; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2017 |
Synthesis, biological evaluation and docking studies of 2,3-dihydroquinazolin-4(1H)-one derivatives as inhibitors of cholinesterases.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophorus; Horses; Humans; Molecular Docking Simulation; Quinazolinones; Structure-Activity Relationship | 2017 |
In silico studies, synthesis and pharmacological evaluation to explore multi-targeted approach for imidazole analogues as potential cholinesterase inhibitors with neuroprotective role for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophorus; Female; Horses; Imidazoles; Male; Maze Learning; Memory Disorders; Mice; Molecular Structure; Neuroprotective Agents; Structure-Activity Relationship | 2018 |
Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Butyrylcholinesterase; Caco-2 Cells; Cell Line, Tumor; Cholinesterase Inhibitors; Drug Design; Humans; Ligands; Models, Molecular; Neuroprotective Agents; Piperidines | 2018 |
Design, synthesis, and biological evaluation of selective and potent Carbazole-based butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Carbazoles; Cholinesterase Inhibitors; Drug Design; Humans; Inhibitory Concentration 50; Kinetics; Molecular Docking Simulation; Neuroprotective Agents; PC12 Cells; Piperidines; Rats | 2018 |
Isoquinoline Alkaloids from Berberis vulgaris as Potential Lead Compounds for the Treatment of Alzheimer's Disease.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Berberis; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Plant Exudates | 2019 |
Design, synthesis, evaluation and molecular modeling study of 4-N-phenylaminoquinolines for Alzheimer disease treatment.
Topics: Acetylcholinesterase; Alzheimer Disease; Aminoquinolines; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Neuroprotective Agents; Structure-Activity Relationship | 2019 |
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzofurans; Butyrylcholinesterase; Catalytic Domain; Cell Line, Tumor; CHO Cells; Cholinesterase Inhibitors; Cricetulus; Drug Design; Humans; Immunologic Factors; Mice; Microglia; Molecular Docking Simulation; Neuroprotective Agents; Peptide Fragments; Protein Binding; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Small Molecule Libraries | 2019 |
Novel N-benzylpiperidine carboxamide derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Eels; Horses; Humans; Models, Molecular; Molecular Structure; Piperidines; Structure-Activity Relationship | 2019 |
Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antineoplastic Agents; Butyrylcholinesterase; Cell Proliferation; Cholinesterase Inhibitors; Dimerization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Electrophorus; Horses; Humans; Ligands; Models, Molecular; Molecular Structure; Neuroprotective Agents; Phenols; Structure-Activity Relationship; Tacrine; Tumor Cells, Cultured | 2019 |
Derivatives of montanine-type alkaloids and their implication for the treatment of Alzheimer's disease: Synthesis, biological activity and in silico study.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Isoquinolines; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2021 |
Evaluation of chromane derivatives: Promising privileged scaffolds for lead discovery within Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Horses; Kinetics; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2022 |
Effects of New Galantamine Derivatives in a Scopolamine Model of Dementia in Mice.
Topics: Alzheimer Disease; Animals; Antioxidants; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Galantamine; Male; Memory, Long-Term; Memory, Short-Term; Mice; Scopolamine | 2021 |
Therapeutic effects of carvacrol on beta-amyloid-induced impairments in in vitro and in vivo models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Galantamine; Hippocampus; Humans; Memory Disorders; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Peptide Fragments; Rats; Superoxide Dismutase; Thymol | 2022 |
Transition-Metal-Mediated Chemo- and Stereoselective Total Synthesis of (-)-Galanthamine.
Topics: Alkaloids; Alzheimer Disease; Galantamine; Humans | 2022 |
Analysis of treatment pattern of anti-dementia medications in newly diagnosed Alzheimer's dementia using OMOP CDM.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Memantine; Phenylcarbamates; Piperidines; Rivastigmine | 2022 |
Neuropsychiatric Symptoms in Dementia: Considering a Clinical Role for Electroencephalography.
Topics: Alzheimer Disease; Dementia; Electroencephalography; Galantamine; Humans; Neuropsychological Tests; Risperidone | 2022 |
A single-molecule with multiple investigations: Synthesis, characterization, computational methods, inhibitory activity against Alzheimer's disease, toxicity, and ADME studies.
Topics: Acetylcholinesterase; Alzheimer Disease; Donepezil; Galantamine; Humans; Molecular Docking Simulation | 2022 |
A Cobalt-Containing Compound as a Stronger Inhibitor than Galantamine to Inhibit Acetylcholinesterase Activity: A New Drug Candidate for Alzheimer's Disease Treatment.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Cobalt; Galantamine; Humans; Molecular Docking Simulation | 2022 |
Synthesis and biological study of new galanthamine-peptide derivatives designed for prevention and treatment of Alzheimer
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Galantamine; Humans; Peptides; Sheep | 2022 |
Kinetic Modeling of Time-Dependent Enzyme Inhibition by Pre-Steady-State Analysis of Progress Curves: The Case Study of the Anti-Alzheimer's Drug Galantamine.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans; Kinetics | 2022 |
Intranasal Oxytocin Attenuates Cognitive Impairment, β-Amyloid Burden and Tau Deposition in Female Rats with Alzheimer's Disease: Interplay of ERK1/2/GSK3β/Caspase-3.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Caspase 3; Cognitive Dysfunction; Disease Models, Animal; Female; Galantamine; Glycogen Synthase Kinase 3 beta; MAP Kinase Signaling System; Oxytocin; Rats; tau Proteins | 2022 |
Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Antioxidants; Cholinesterase Inhibitors; Galantamine; Humans; Molecular Docking Simulation | 2022 |
Association study identifies genetic determinants and non-genetic factors on steady-state plasma and therapeutic outcome of galantamine in mixed dementia.
Topics: Alzheimer Disease; Apolipoproteins E; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Galantamine; Genotype; Humans; Treatment Outcome | 2022 |
Risk of Serious Adverse Events Associated With Individual Cholinesterase Inhibitors Use in Older Adults With Dementia: A Population-Based Cohort Study.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Donepezil; Female; Galantamine; Humans; Indans; Male; Medicare; Phenylcarbamates; Piperidines; Retrospective Studies; Rivastigmine; United States | 2022 |
Lemborexant add-on further improves the effect of galantamine on sleep-wake disorder in Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans; Pyridines; Pyrimidines; Sleep; Sleep Wake Disorders | 2022 |
Dysphagia Risk in Patients Prescribed Rivastigmine: A Systematic Analysis of FDA Adverse Event Reporting System.
Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Clozapine; Deglutition Disorders; Donepezil; Galantamine; Humans; Memantine; Penicillamine; Risk Management; Rivastigmine; United States; United States Food and Drug Administration | 2022 |
Kinetic and structural studies on the inhibition of acetylcholinesterase and butyrylcholinesterase by a series of multitarget-directed galantamine-peptide derivatives.
Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Galantamine; Humans; Molecular Docking Simulation; Molecular Structure; Peptide Fragments; Structure-Activity Relationship | 2022 |
Novel Morpholine-Bearing Quinoline Derivatives as Potential Cholinesterase Inhibitors: The Influence of Amine, Carbon Linkers and Phenylamino Groups.
Topics: Acetylcholinesterase; Alzheimer Disease; Amines; Aminoquinolines; Benzothiazoles; Carbon; Cholinesterase Inhibitors; Galantamine; Humans; Hydroxyquinolines; Kinetics; Molecular Docking Simulation; Morpholines; Structure-Activity Relationship; Sulfonic Acids | 2022 |
Resveratrol-Maltol and Resveratrol-Thiophene Hybrids as Cholinesterase Inhibitors and Antioxidants: Synthesis, Biometal Chelating Capability and Crystal Structure.
Topics: Alzheimer Disease; Antioxidants; Chelating Agents; Cholinesterase Inhibitors; Cholinesterases; Galantamine; Humans; Ligands; Molecular Docking Simulation; Pyrones; Resveratrol; Structure-Activity Relationship; Thiophenes; Trace Elements | 2022 |
Interactions of Isoquinoline Alkaloids with Transition Metals Iron and Copper.
Topics: Alzheimer Disease; Chelating Agents; Copper; Cytostatic Agents; Dimethyl Sulfoxide; Galantamine; Humans; Hydroxyl Radical; Iron; Isoquinolines; Reactive Oxygen Species; Reducing Agents; Salts | 2022 |
Evaluation of Anti-Alzheimer Activity of Synthetic Coumarins by Combination of in Vitro and in Silico Approaches.
Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Coumarins; Galantamine; Humans; Molecular Docking Simulation; Neuroblastoma; Structure-Activity Relationship | 2022 |
Real-world effects of anti-dementia treatment on mortality in patients with Alzheimer´s dementia.
Topics: Alzheimer Disease; Donepezil; Female; Galantamine; Humans; Indans; Male; Phenylcarbamates; Piperidines; Retrospective Studies; Rivastigmine | 2022 |
Nose-to-brain delivery of galantamine loaded nanospray dried polyacrylic acid/taurodeoxycholate mixed matrix as a protective therapy in lipopolysaccharide-induced Alzheimer's in mice model.
Topics: Administration, Intranasal; Alzheimer Disease; Animals; Brain; Drug Carriers; Galantamine; Lipopolysaccharides; Mice; Nasal Mucosa; Particle Size | 2023 |
Alkaloid Profile in Wild Autumn-Flowering Daffodils and Their Acetylcholinesterase Inhibitory Activity.
Topics: Acetylcholinesterase; Alzheimer Disease; Amaryllidaceae; Amaryllidaceae Alkaloids; Cholinesterase Inhibitors; Galantamine; Narcissus | 2023 |
Palladium-Catalyzed Synthesis, Acetylcholinesterase Inhibition, and Neuroprotective Activities of
Topics: Acetylcholinesterase; Alzheimer Disease; Catalysis; Cholinesterase Inhibitors; Galantamine; Humans; Hydrogen Peroxide; Molecular Docking Simulation; Molecular Structure; Neuroblastoma; Neuroprotective Agents; Palladium; Structure-Activity Relationship | 2023 |
Static Binding and Dynamic Transporting-Based Design of Specific Ring-Chain-Ring Acetylcholinesterase Inhibitor: From Galantamine to Natural Product.
Topics: Acetylcholinesterase; Alzheimer Disease; Biological Products; Cholinesterase Inhibitors; Galantamine; Humans; Molecular Docking Simulation | 2023 |
Proposing novel natural compounds against Alzheimer's disease targeting acetylcholinesterase.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Molecular Docking Simulation; Neuroblastoma; Thiamine | 2023 |
Prevalence of treated patients with Alzheimer's disease: current trends and COVID-19 impact.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; COVID-19; Donepezil; Female; Galantamine; Humans; Indans; Male; Memantine; Pandemics; Phenylcarbamates; Piperidines; Prevalence; Retrospective Studies; Rivastigmine | 2023 |
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Galantamine; Humans; Memantine; Mice; Receptors, N-Methyl-D-Aspartate | 2023 |
Inhibition mechanism of fisetin on acetylcholinesterase and its synergistic effect with galantamine.
Topics: Acetylcholinesterase; Alzheimer Disease; Catalytic Domain; Cholinesterase Inhibitors; Computer Simulation; Galantamine; Humans; Molecular Docking Simulation | 2024 |
Quercetin-1,2,3-Triazole Hybrids as Multifunctional Anti-Alzheimer's Agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Drug Design; Galantamine; Humans; Hydrogen Peroxide; Neuroprotective Agents; Quercetin; Structure-Activity Relationship | 2023 |
Risk of rhabdomyolysis with donepezil compared with rivastigmine or galantamine: a population-based cohort study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Hospitalization; Humans; Male; Ontario; Retrospective Studies; Rhabdomyolysis; Risk Assessment; Rivastigmine | 2019 |
Early administration of galantamine from preplaque phase suppresses oxidative stress and improves cognitive behavior in APPswe/PS1dE9 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cholinesterase Inhibitors; Cognitive Behavioral Therapy; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Galantamine; Humans; Inflammation; Mice; Microglia; Oxidative Stress; Protein Aggregation, Pathological; Reactive Oxygen Species; Ribosomal Proteins; RNA-Binding Proteins | 2019 |
Neuroprotective Effects of Apocynin and Galantamine During the Chronic Administration of Scopolamine in an Alzheimer's Disease Model.
Topics: Acetophenones; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Galantamine; Hippocampus; Male; NADPH Oxidase 2; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Scopolamine | 2020 |
Cholinesterase as a Target for Drug Development in Alzheimer's Disease.
Topics: Acetylcholine; Alzheimer Disease; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Drug Development; Galantamine; Humans; Memantine; Rivastigmine | 2020 |
Medical interventions suppressed progression of advanced Alzheimer's disease more than mild Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Disease Progression; Donepezil; Female; Galantamine; Humans; Japan; Male; Memantine; Mental Status and Dementia Tests; Retrospective Studies; Rivastigmine | 2020 |
Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors enhance procognitive effects of conventional anti-Alzheimer drugs in scopolamine-treated rats.
Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Drug Synergism; Excitatory Amino Acid Antagonists; Galantamine; Isoxazoles; Memantine; Nootropic Agents; Phenylurea Compounds; Rats; Recognition, Psychology; Scopolamine | 2020 |
Pisa syndrome induced by switching of a choline-esterase inhibitor treatment from donepezil to galantamine: a case report.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Humans; Middle Aged; Tardive Dyskinesia | 2020 |
Multiple target-based combination therapy of galantamine, memantine and lycopene for the possible treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Lycopene; Memantine; Piperidines | 2020 |
Treatment pathway analysis of newly diagnosed dementia patients in four electronic health record databases in Europe.
Topics: Alzheimer Disease; Electronic Health Records; Europe; Galantamine; Humans; Indans; Italy; Netherlands; Phenylcarbamates; Piperidines; Retrospective Studies | 2021 |
Pharmaceutical Treatment for Alzheimer's Disease and Related Dementias: Utilization and Disparities.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Dementia; Donepezil; Dopamine Agents; Female; Galantamine; Healthcare Disparities; Humans; Male; Medicare; Memantine; Nootropic Agents; Patient Acceptance of Health Care; Rivastigmine; Treatment Outcome; United States | 2020 |
Galantamine-Curcumin Hybrids as Dual-Site Binding Acetylcholinesterase Inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Binding Sites; Blood-Brain Barrier; Cell Line; Cholinesterase Inhibitors; Combinatorial Chemistry Techniques; Curcumin; Galantamine; Humans; Mice; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2020 |
Gas-phase basicity and proton affinity measurements of Alzheimer's disease drugs by the extended kinetic method and a theoretical investigation.
Topics: Alzheimer Disease; Curcumin; Galantamine; Humans; Neuroprotective Agents; Protons; Rivastigmine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2020 |
Evaluation of the Therapeutic Effect of Lycoramine on Alzheimer's Disease in Mouse Model.
Topics: Alzheimer Disease; Amaryllidaceae Alkaloids; Amyloid beta-Peptides; Animals; Disease Models, Animal; Galantamine; Mice; Mice, Transgenic | 2021 |
Therapeutic Potential of Multifunctional Derivatives of Cholinesterase Inhibitors.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Donepezil; Galantamine; Rivastigmine; Tacrine | 2021 |
Revealing the cholinergic inhibition mechanism of Alzheimer's by galantamine: a metadynamics simulation study.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans; Protons | 2022 |
Post-market utilization patterns of Alzheimer's disease treatments in South Korea: comparison with countries with universal health coverage.
Topics: Alzheimer Disease; Australia; Cholinesterase Inhibitors; Donepezil; Galantamine; Global Health; Humans; Memantine; Product Surveillance, Postmarketing; Republic of Korea; Rivastigmine; Universal Health Care | 2021 |
Integrating Narcissus-derived galanthamine production into traditional upland farming systems.
Topics: Alzheimer Disease; Animals; Crop Production; Galantamine; Humans; Narcissus; Sheep | 2021 |
Early Start of Anti-Dementia Medication Delays Transition to 24-Hour Care in Alzheimer's Disease Patients: A Finnish Nationwide Cohort Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Donepezil; Female; Finland; Galantamine; Humans; Male; Memantine; Nootropic Agents; Nursing Homes; Retrospective Studies; Rivastigmine; Time-to-Treatment | 2021 |
The Clinician's Interview-Based Impression of Change (Plus caregiver input) and goal attainment in two dementia drug trials: Clinical meaningfulness and the initial treatment response.
Topics: Aged; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Double-Blind Method; Female; Galantamine; Humans; Male; Nootropic Agents; Patient Reported Outcome Measures; Severity of Illness Index | 2021 |
The Association Between Use of Rivastigmine and Pneumonia: Systematic Analysis of FDA Adverse Event Reporting System.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Databases, Factual; Donepezil; Female; Galantamine; Humans; Male; Nootropic Agents; Pneumonia; Rivastigmine; Sex Factors; United States; United States Food and Drug Administration | 2021 |
New Galantamine Derivatives with Inhibitory Effect on Acetylcholinesterase Activity.
Topics: Alzheimer Disease; Animals; Antioxidants; Brain; Catalase; Cholinesterase Inhibitors; Galantamine; Glutathione Peroxidase; Humans; Lipid Peroxidation; Male; Memory; Mice; Mice, Inbred ICR; Oxidative Stress; Superoxide Dismutase | 2021 |
Clinical meaningfulness of Alzheimer's Disease Assessment Scale-Cognitive subscale change in relation to goal attainment in patients on cholinesterase inhibitors.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Canada; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition Disorders; Donepezil; Double-Blind Method; Female; Galantamine; Goals; Humans; Indans; Male; Multicenter Studies as Topic; Outcome Assessment, Health Care; Piperidines; Severity of Illness Index | 2017 |
Co-modulation of an allosteric modulator of nicotinic receptor-cholinesterase inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse.
Topics: Allosteric Regulation; Alzheimer Disease; Aniline Compounds; Animals; Cholinesterase Inhibitors; Galantamine; Male; Memory Disorders; Mice; Nicotinic Antagonists; Piperidines; Receptors, Nicotinic; Receptors, Serotonin, 5-HT4; Scopolamine; Serotonin 5-HT4 Receptor Agonists | 2017 |
Assessing the binding of cholinesterase inhibitors by docking and molecular dynamics studies.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Hydrogen Bonding; Indans; Molecular Conformation; Molecular Dynamics Simulation; Piperidines; Rivastigmine; Torpedo | 2017 |
Could delirium and anti-dementia drugs effect the treatment of agitated nursing home residents with Alzheimer dementia?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Delirium; Donepezil; Female; Galantamine; Humans; Male; Nursing Homes; Prognosis; Psychomotor Agitation; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2018 |
rCBF and cognitive impairment changes assessed by SPECT and ADAS-cog in late-onset Alzheimer's disease after 18 months of treatment with the cholinesterase inhibitors donepezil or galantamine.
Topics: Aged; Alzheimer Disease; Brain; Brain Mapping; Cerebrovascular Circulation; Cholinesterase Inhibitors; Cognitive Dysfunction; Cross-Sectional Studies; Donepezil; Female; Follow-Up Studies; Galantamine; Humans; Imaging, Three-Dimensional; Male; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2019 |
Galantamine inhibits β-amyloid-induced cytostatic autophagy in PC12 cells through decreasing ROS production.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Autophagy; Cell Proliferation; Cytostatic Agents; Drug Evaluation, Preclinical; Galantamine; NADPH Oxidase 4; PC12 Cells; Peptide Fragments; Rats; Reactive Oxygen Species | 2018 |
Hypothesis: apo-lactoferrin-Galantamine Proteo-alkaloid Conjugate for Alzheimer's disease Intervention.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Apoproteins; Binding Sites; Brain; Disease Management; Galantamine; Glycoconjugates; Humans; Iron; Iron Chelating Agents; Lactoferrin; Models, Molecular; Neuroprotective Agents; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; tau Proteins | 2018 |
Acceleration of NLRP3 inflammasome by chronic cerebral hypoperfusion in Alzheimer's disease model mouse.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain Ischemia; Caspase 1; Cerebral Cortex; Cerebrovascular Circulation; Collagen; Disease Models, Animal; Galantamine; Inflammasomes; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein | 2019 |
Acute cholinergic syndrome in a patient with Alzheimer's disease taking the prescribed dose of galantamine.
Topics: Aged, 80 and over; Alzheimer Disease; Atrophy; Brain; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Galantamine; Humans; Male; Syndrome; Tomography, X-Ray Computed | 2018 |
Nose to Brain Delivery of Galantamine Loaded Nanoparticles: In-vivo Pharmacodynamic and Biochemical Study in Mice.
Topics: Acetylcholinesterase; Adhesiveness; Administration, Intranasal; Administration, Oral; Alzheimer Disease; Animals; Behavior, Animal; Biological Availability; Blood-Brain Barrier; Chitosan; Cholinesterase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Galantamine; Humans; Male; Maze Learning; Mice; Nanoparticles; Nasal Mucosa; Nootropic Agents; Piracetam; Scopolamine; Treatment Outcome | 2019 |
Synthesis of New Galanthamine-Peptide Derivatives Designed for Prevention and Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Galantamine; Humans; Mice; Peptides | 2019 |
Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer's Disease.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Binding Sites; Cholinesterase Inhibitors; Databases, Chemical; Donepezil; Drug Discovery; Galantamine; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Quantitative Structure-Activity Relationship; Sesquiterpenes | 2019 |
Design of Natural-Product-Inspired Multitarget Ligands by Machine Learning.
Topics: Acetylcholinesterase; Alzheimer Disease; Biological Products; Cell Line, Tumor; Cholinesterase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Galantamine; Humans; Ligands; Machine Learning; Molecular Docking Simulation; Molecular Structure; Neuroprotective Agents; Stereoisomerism | 2019 |
Development and in vitro evaluation of pressure sensitive adhesive patch for the transdermal delivery of galantamine: Effect of penetration enhancers and crystallization inhibition.
Topics: Adhesives; Administration, Cutaneous; Aged; Alzheimer Disease; Cadaver; Crystallization; Diffusion; Drug Carriers; Drug Evaluation, Preclinical; Drug Liberation; Female; Galantamine; Humans; Limonene; Male; Medication Adherence; Nootropic Agents; Oleic Acid; Permeability; Polymers; Pressure; Skin; Skin Absorption; Spectroscopy, Fourier Transform Infrared; Transdermal Patch | 2019 |
Profiling of acetylcholinesterase inhibitory alkaloids from some
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Amaryllidaceae; Amaryllidaceae Alkaloids; Catalytic Domain; Cholinesterase Inhibitors; Computer Simulation; Crinum; Galantamine; Gas Chromatography-Mass Spectrometry; Humans; Molecular Docking Simulation; Multivariate Analysis; Plant Extracts; Plant Leaves; Plant Roots | 2021 |
Effect of CYP2D6 and CYP3A4 Genotypes on the Efficacy of Cholinesterase Inhibitors in Southern Chinese Patients With Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Donepezil; Female; Follow-Up Studies; Galantamine; Genotype; Hong Kong; Humans; Male; Pharmacogenetics; Pharmacogenomic Testing; Rivastigmine | 2019 |
Is drug treatment for dementia followed up in primary care? A Swedish study of dementia clinics and referring primary care centres.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Dementia, Vascular; Donepezil; Female; Galantamine; Humans; Indans; Male; Medical Records; Memantine; Nootropic Agents; Phenylcarbamates; Piperidines; Practice Guidelines as Topic; Practice Patterns, Physicians'; Primary Health Care; Retrospective Studies; Rivastigmine; Sweden; Treatment Outcome | 2013 |
Galantamine-associated nightmares and anxiety.
Topics: Aged, 80 and over; Alzheimer Disease; Anxiety; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Dreams; Galantamine; Humans; Male; Quality of Life; Recurrence | 2013 |
Blood pro-inflammatory cytokines in Alzheimer's disease in relation to the use of acetylcholinesterase inhibitors.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholinesterase Inhibitors; Donepezil; Enzyme-Linked Immunosorbent Assay; Female; Galantamine; Humans; Indans; Interleukin-1beta; Interleukin-6; Male; Phenylcarbamates; Piperidines; Rivastigmine; Sex Factors; Tumor Necrosis Factor-alpha | 2013 |
Effect of long-term treatment with galantamine on weight of patients with Alzheimer's dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Body Weight; Caregivers; Cholinesterase Inhibitors; Female; Galantamine; Humans; Longitudinal Studies; Male; Netherlands; Retrospective Studies; Sex Factors; Weight Loss | 2013 |
Acetylcholineestarase-inhibiting alkaloids from Lycoris radiata delay paralysis of amyloid beta-expressing transgenic C. elegans CL4176.
Topics: Acetylcholinesterase; Alzheimer Disease; Amaryllidaceae Alkaloids; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Cholinesterase Inhibitors; Disease Models, Animal; Galantamine; Gene Expression; Humans; Longevity; Lycoris; Oxidative Stress; Paralysis; Peptide Fragments; Phenanthridines | 2013 |
A longitudinal study of risk factors for community-based home help services in Alzheimer's disease: the influence of cholinesterase inhibitor therapy.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Chi-Square Distribution; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Home Care Services; Humans; Indans; Linear Models; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Phenylcarbamates; Piperidines; Proportional Hazards Models; Prospective Studies; Risk Factors; Rivastigmine; Treatment Outcome | 2013 |
Utility of an effect size analysis for communicating treatment effectiveness: a case study of cholinesterase inhibitors for Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Area Under Curve; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Treatment Outcome | 2013 |
Effect of galantamine on platelet functions in healthy elderly people.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood Platelets; Cardiovascular Diseases; Female; Galantamine; Healthy Volunteers; Humans; Male; Platelet Aggregation | 2013 |
In silico and in vitro studies to elucidate the role of Cu2+ and galanthamine as the limiting step in the amyloid beta (1-42) fibrillation process.
Topics: Alzheimer Disease; Amino Acid Sequence; Amino Acids; Amyloid; Amyloid beta-Peptides; Circular Dichroism; Copper; Galantamine; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Sequence Data; Peptide Fragments; Protein Folding; Protein Structure, Secondary; Spectrometry, Fluorescence | 2013 |
Synthesis of imperatorin analogs and their evaluation as acetylcholinesterase and butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Furocoumarins; Galantamine; Molecular Docking Simulation; Structure-Activity Relationship | 2013 |
An over expression APP model for anti-Alzheimer disease drug screening created by zinc finger nuclease technology.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; BALB 3T3 Cells; Base Sequence; Cholinesterase Inhibitors; Deoxyribonucleases; DNA Cleavage; Donepezil; Drug Evaluation, Preclinical; Galantamine; Gene Expression; Genetic Engineering; Green Fluorescent Proteins; Homologous Recombination; Humans; Ibuprofen; Indans; Mice; Molecular Sequence Data; Peptide Fragments; Piperidines; Recombinant Proteins; Zinc Fingers | 2013 |
Galantamine slows down plaque formation and behavioral decline in the 5XFAD mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Female; Galantamine; Male; Maze Learning; Mice; Neurons; Plaque, Amyloid; Sex Factors | 2014 |
Antidementia drug use among community-dwelling individuals with Alzheimer's disease in Finland: a nationwide register-based study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Diagnostic and Statistical Manual of Mental Disorders; Donepezil; Drug Monitoring; Drug Prescriptions; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Finland; Follow-Up Studies; Galantamine; Guideline Adherence; Humans; Indans; Male; Memantine; Nootropic Agents; Phenylcarbamates; Piperidines; Practice Guidelines as Topic; Proportional Hazards Models; Registries; Rivastigmine | 2014 |
[Dementia solved with surgery: report of a case].
Topics: Alzheimer Disease; Consciousness Disorders; Delayed Diagnosis; Dementia; Diagnostic Errors; Diagnostic Imaging; False Negative Reactions; Female; Galantamine; Humans; Hyperinsulinism; Hypoglycemia; Insulinoma; Middle Aged; Nootropic Agents; Pancreatectomy; Pancreatic Neoplasms; Remission Induction; Weight Gain | 2015 |
Medical Resource Value Appraisal for Leucojum aestivum in Turkey.
Topics: Alzheimer Disease; Amaryllidaceae; Cholinesterase Inhibitors; Galantamine; Humans; Plants, Medicinal; Turkey | 2014 |
New developments in redox chemical delivery systems by means of 1,4-dihydroquinoline-based targetor: application to galantamine delivery to the brain.
Topics: Acetylcholinesterase; Alzheimer Disease; Brain; Cholinesterase Inhibitors; Drug Delivery Systems; Galantamine; Humans; Molecular Structure; Oxidation-Reduction; Quinolines | 2014 |
Cloning and characterization of a norbelladine 4'-O-methyltransferase involved in the biosynthesis of the Alzheimer's drug galanthamine in Narcissus sp. aff. pseudonarcissus.
Topics: Alkaloids; Alzheimer Disease; Amino Acid Sequence; Cloning, Molecular; DNA, Complementary; Escherichia coli; Galantamine; Humans; Narcissus; Protein O-Methyltransferase | 2014 |
FOXO1 locus and acetylcholinesterase inhibitors in elderly patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Brain; Cholinesterase Inhibitors; Donepezil; Female; Forkhead Box Protein O1; Forkhead Transcription Factors; Galantamine; Gene Frequency; Genetic Loci; Genotype; Haplotypes; Humans; Indans; Male; Oxidative Stress; Phenylcarbamates; Piperidines; Prospective Studies; Rivastigmine | 2014 |
Combination Therapy of Cholinesterase Inhibitor (Donepezil or Galantamine) plus Memantine in the Okayama Memantine Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Donepezil; Dopamine Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Galantamine; Humans; Indans; Japan; Male; Memantine; Neuropsychological Tests; Piperidines; Psychiatric Status Rating Scales | 2015 |
Treatment with rivastigmine or galantamine and risk of urinary incontinence: results from a Dutch database study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Cross-Over Studies; Databases, Factual; Female; Follow-Up Studies; Galantamine; Humans; Longitudinal Studies; Male; Netherlands; Risk Factors; Rivastigmine; Treatment Outcome; Urinary Incontinence | 2015 |
Nasal Application of the Galantamine Pro-drug Memogain Slows Down Plaque Deposition and Ameliorates Behavior in 5X Familial Alzheimer's Disease Mice.
Topics: Administration, Intranasal; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Cholinesterase Inhibitors; Conditioning, Psychological; Disease Models, Animal; Fear; Galantamine; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Muscle Strength; Mutation; Plaque, Amyloid; Presenilin-1; Prodrugs | 2015 |
Interaction between anti-Alzheimer and antipsychotic drugs in modulating extrapyramidal motor disorders in mice.
Topics: Alzheimer Disease; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Galantamine; Haloperidol; Hypokinesia; Indans; Male; Mice, Inbred Strains; Nootropic Agents; Piperidines; Receptor, Serotonin, 5-HT1A; Receptors, Muscarinic; Serotonin Agents | 2015 |
Formulation and evaluation of galantamine gel as drug reservoir in transdermal patch delivery system.
Topics: Administration, Cutaneous; Alzheimer Disease; Chemistry, Pharmaceutical; Cholinesterase Inhibitors; Galantamine; Gels; Humans; In Vitro Techniques | 2015 |
Cognitive and affective benefits of combination therapy with galantamine plus cognitive rehabilitation for Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Cognitive Behavioral Therapy; Female; Follow-Up Studies; Galantamine; Humans; Male; Physical Therapy Modalities; Psychiatric Status Rating Scales; Retrospective Studies; Time Factors; Treatment Outcome | 2016 |
Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Death; Galantamine; Hippocampus; Melatonin; Models, Biological; Neuroprotective Agents; Okadaic Acid; Phosphorylation; Protein Aggregates; Rats, Sprague-Dawley; tau Proteins; Tissue Culture Techniques | 2016 |
Formulation optimization of galantamine hydrobromide loaded gel drug reservoirs in transdermal patch for Alzheimer's disease.
Topics: Administration, Cutaneous; Alzheimer Disease; Delayed-Action Preparations; Ethanolamines; Galantamine; Gels; Humans; Hydrogen-Ion Concentration; Models, Chemical; Polyvinyls; Reproducibility of Results; Software; Transdermal Patch | 2015 |
Predicting the neural effect of switching from donepezil to galantamine based on single-photon emission computed tomography findings in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apathy; Cholinesterase Inhibitors; Donepezil; Executive Function; Female; Galantamine; Humans; Indans; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Piperidines; Prospective Studies; Tomography, Emission-Computed, Single-Photon | 2016 |
Synthesis of New Peptide Derivatives of Galanthamine Designed for Prevention and Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Galantamine; Humans; Mice; Peptides | 2015 |
Galantamine derivatives with indole moiety: Docking, design, synthesis and acetylcholinesterase inhibitory activity.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Drug Design; Galantamine; Humans; Indoles; Liliaceae; Molecular Docking Simulation; Structure-Activity Relationship | 2015 |
Adverse Drug Reactions Reported With Cholinesterase Inhibitors: An Analysis of 16 Years of Individual Case Safety Reports From VigiBase.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug-Related Side Effects and Adverse Reactions; Europe; Female; Galantamine; Humans; Indans; Male; Medication Errors; North America; Pharmacovigilance; Piperidines; Rivastigmine; World Health Organization | 2015 |
Long-Term Efficacy of Galantamine in Alzheimer's Disease: The Okayama Galantamine Study (OGS).
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Female; Galantamine; Humans; Japan; Male; Nootropic Agents; Psychiatric Status Rating Scales; Psychological Tests; Sex Factors; Time Factors; Treatment Outcome | 2015 |
Clinical Benefits for Older Alzheimer's Disease Patients: Okayama Late Dementia Study (OLDS).
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Donepezil; Female; Follow-Up Studies; Galantamine; Humans; Indans; Japan; Male; Memantine; Piperidines; Retrospective Studies; Rivastigmine; Treatment Outcome | 2015 |
Galantamine attenuates amyloid-β deposition and astrocyte activation in APP/PS1 transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Disease Models, Animal; Galantamine; Hippocampus; Interleukin-6; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Tumor Necrosis Factor-alpha | 2015 |
NGA- A Novel Hypothetical Drug Model: Combinatorial Approach to Multifactorial Alzheimer's Disease.
Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Disulfides; Drug Combinations; Galantamine; Humans; Levodopa; Plaque, Amyloid | 2015 |
Real-world evaluation of compliance and preference in Alzheimer's disease treatment.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Asia; Attitude of Health Personnel; Caregivers; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Humans; Indans; Male; Medication Adherence; Memantine; Middle East; Patient Preference; Physicians; Piperidines; Prospective Studies; Rivastigmine | 2015 |
Adverse Effects of Cholinesterase Inhibitors in Dementia, According to the Pharmacovigilance Databases of the United-States and Canada.
Topics: Adverse Drug Reaction Reporting Systems; Alzheimer Disease; Canada; Cholinesterase Inhibitors; Databases, Factual; Dementia; Donepezil; Galantamine; Humans; Indans; Pharmacovigilance; Piperidines; Rivastigmine; United States; United States Food and Drug Administration | 2015 |
Effect of alpha-7 nicotinic acetylcholine receptor activation on beta-amyloid induced recognition memory impairment. Possible role of neurovascular function.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cholinesterase Inhibitors; Disease Models, Animal; Galantamine; Laser-Doppler Flowmetry; Male; Memory Disorders; Mice, Inbred BALB C; Neuropsychological Tests; Neurovascular Coupling; Peptide Fragments; Quinuclidines; Recognition, Psychology; Reproducibility of Results; Time Factors; Treatment Outcome | 2015 |
(I) Pharmacological profiling of a novel modulator of the α7 nicotinic receptor: Blockade of a toxic acetylcholinesterase-derived peptide increased in Alzheimer brains.
Topics: Acetylcholinesterase; Allosteric Site; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Animals; Biomarkers; Brain; Cell Survival; Cholinesterase Inhibitors; Galantamine; Humans; Hydrogen Peroxide; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Peptides, Cyclic; Rats; tau Proteins; Tissue Culture Techniques | 2016 |
Mild versus moderate stages of Alzheimer's disease: three-year outcomes in a routine clinical setting of cholinesterase inhibitor therapy.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Donepezil; Female; Galantamine; Humans; Indans; Male; Mental Status Schedule; Piperidines; Prospective Studies; Rivastigmine; Severity of Illness Index; Treatment Outcome | 2016 |
Pharmacological, toxicological and neuronal localization assessment of galantamine/chitosan complex nanoparticles in rats: future potential contribution in Alzheimer's disease management.
Topics: Acetylcholinesterase; Administration, Intranasal; Alzheimer Disease; Animals; Brain; Chitosan; Drug Delivery Systems; Galantamine; Male; Nanoparticles; Neurons; Rats; Rats, Wistar | 2016 |
Strong Impact of Chronic Cerebral Hypoperfusion on Neurovascular Unit, Cerebrovascular Remodeling, and Neurovascular Trophic Coupling in Alzheimer's Disease Model Mouse.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Cerebrovascular Disorders; Disease Models, Animal; Disease Progression; Galantamine; Humans; Male; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Neuroprotective Agents; Neurovascular Coupling; Nootropic Agents; Receptors, Nicotinic | 2016 |
Disruption of White Matter Integrity by Chronic Cerebral Hypoperfusion in Alzheimer's Disease Mouse Model.
Topics: Alzheimer Disease; Animals; Ankyrins; Brain Ischemia; Cell Adhesion Molecules; Corpus Callosum; Disease Models, Animal; Galantamine; Male; Mice; Mice, Inbred C57BL; Myelin-Associated Glycoprotein; Nerve Growth Factors; Nootropic Agents; White Matter | 2016 |
Ceria-containing uncoated and coated hydroxyapatite-based galantamine nanocomposites for formidable treatment of Alzheimer's disease in ovariectomized albino-rat model.
Topics: Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cerebral Cortex; Cerium; Chitosan; Chlorides; Disease Models, Animal; Drug Carriers; Durapatite; Dynamic Light Scattering; Female; Galantamine; Hippocampus; Nanocomposites; Ovariectomy; Rats; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2016 |
Chronic Cerebral Hypoperfusion Accelerates Alzheimer's Disease Pathology with Cerebrovascular Remodeling in a Novel Mouse Model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Carotid Stenosis; Cholinesterase Inhibitors; Disease Models, Animal; Galantamine; Gene Expression Regulation; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Models, Cardiovascular; Plaque, Amyloid; Postural Balance; Psychomotor Performance; Receptors, Nicotinic; White Matter | 2016 |
The combination of memantine and galantamine improves cognition in rats: The synergistic role of the α7 nicotinic acetylcholine and NMDA receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Antiparkinson Agents; Cholinesterase Inhibitors; Cognition; Disease Models, Animal; Galantamine; Male; Memantine; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2016 |
Effect of mesenchymal stem cells and galantamine nanoparticles in rat model of Alzheimer's disease.
Topics: Adrenergic beta-Agonists; Alzheimer Disease; Animals; Behavior, Animal; Cells, Cultured; Combined Modality Therapy; Galantamine; Inflammation Mediators; Isoproterenol; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Nanoparticles; Parasympathomimetics; Rats; Rats, Wistar | 2016 |
In Vivo Characterization of ARN14140, a Memantine/Galantamine-Based Multi-Target Compound for Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Galantamine; Memantine; Mice; Mice, Transgenic; Peptide Fragments | 2016 |
In Vitro Effects of Cognitives and Nootropics on Mitochondrial Respiration and Monoamine Oxidase Activity.
Topics: Alzheimer Disease; Animals; Brain; Cholinesterase Inhibitors; Cognition; Donepezil; Galantamine; Indans; Memantine; Mitochondria; Monoamine Oxidase; Nootropic Agents; Oxygen Consumption; Piperidines; Rivastigmine; Swine | 2017 |
Use of antidementia drugs and risk of pneumonia in older persons with Alzheimer's disease.
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Female; Finland; Galantamine; Hospitalization; Humans; Indans; Male; Memantine; Middle Aged; Piperidines; Pneumonia; Risk; Rivastigmine | 2017 |
Therapeutic effects of drug switching between acetylcholinesterase inhibitors in patients with Alzheimer's disease.
Topics: Activities of Daily Living; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Substitution; Galantamine; Humans; Retrospective Studies; Rivastigmine; Treatment Outcome | 2017 |
Galantamine has impact on immunity in mice exposed to keyhole limpet hemocyanin.
Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Animals; Anti-Inflammatory Agents; Cholinesterase Inhibitors; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Female; Galantamine; Hemocyanins; Immunoglobulins; Inflammation Mediators; Macrophages; Mice; Mice, Inbred BALB C; Receptors, Nicotinic | 2017 |
Tolerability of Cholinesterase Inhibitors: A Population-Based Study of Persistence, Adherence, and Switching.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Tolerance; Female; Galantamine; Humans; Indans; Male; Medication Adherence; Piperidines; Rivastigmine | 2017 |
Different clinical effect of four antidementia drugs for Alzheimer's disease patients depending on white matter severity.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Donepezil; Female; Galantamine; Humans; Male; Memantine; Nootropic Agents; Rivastigmine; Severity of Illness Index; Treatment Outcome; White Matter | 2017 |
Galantamine-induced pisa syndrome: memantine as an alternative.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Dystonic Disorders; Female; Galantamine; Humans; Memantine; Syndrome | 2008 |
Comparison of cholinesterase inhibitor utilization patterns and associated health care costs in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Databases, Factual; Donepezil; Drug Costs; Female; Follow-Up Studies; Galantamine; Health Care Costs; Humans; Indans; Male; Multivariate Analysis; Patient Compliance; Phenylcarbamates; Piperidines; Practice Patterns, Physicians'; Retrospective Studies; Rivastigmine | 2008 |
[Galantamine].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Contraindications; Drug Monitoring; Galantamine; Humans; Nootropic Agents; Nurse's Role; Patient Education as Topic; Patient Selection; Risk Factors | 2008 |
The effect of Galantamine on sleep quality in Thai Alzheimer's disease patients.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cholinesterase Inhibitors; Female; Galantamine; Health Status Indicators; Humans; Male; Risk Factors; Sleep; Sleep Wake Disorders; Thailand | 2008 |
Galantamine-induced improvements in cognitive function are not related to alterations in alpha(4)beta (2) nicotinic receptors in early Alzheimer's disease as measured in vivo by 2-[18F]fluoro-A-85380 PET.
Topics: Aged; Alzheimer Disease; Arousal; Azetidines; Cognition; Female; Fluorine Radioisotopes; Galantamine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Nootropic Agents; Positron-Emission Tomography; Psychomotor Performance; Pyridines; Radiopharmaceuticals; Reaction Time; Receptors, Nicotinic; Space Perception | 2009 |
Treatment with galantamine and time to nursing home placement in Alzheimer's disease patients with and without cerebrovascular disease.
Topics: Aged; Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Female; Follow-Up Studies; Galantamine; Humans; Institutionalization; Long-Term Care; Male; Nursing Homes; Severity of Illness Index; Statistics as Topic; Time Factors; Treatment Outcome | 2009 |
The SERAD study of the safety and efficacy of galantamine in severe Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Clinical Trials as Topic; Galantamine; Humans; Nootropic Agents; Randomized Controlled Trials as Topic | 2009 |
Cholinergic modulation of the cerebral metabolic response to citalopram in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Area Under Curve; Biomarkers; Brain; Case-Control Studies; Cholinesterase Inhibitors; Citalopram; Drug Synergism; Female; Galantamine; Glucose; Humans; Male; Positron-Emission Tomography; Prolactin; Selective Serotonin Reuptake Inhibitors | 2009 |
Simultaneous determination of galantamine, rivastigmine and NAP 226-90 in plasma by MEKC and its application in Alzheimer's disease.
Topics: Adult; Alzheimer Disease; Benzylamines; Buffers; Cholinesterase Inhibitors; Chromatography, Micellar Electrokinetic Capillary; Drug Monitoring; Galantamine; Humans; Male; Phenethylamines; Phenols; Phenylcarbamates; Phosphoric Acids; Reproducibility of Results; Rivastigmine; Sensitivity and Specificity; Solvents; Surface-Active Agents | 2009 |
Adherence to cholinesterase inhibitors in patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Humans; Indans; Male; Medication Adherence; Middle Aged; Phenylcarbamates; Piperidines; Rivastigmine | 2009 |
Galantamine protects against oxidative stress induced by amyloid-beta peptide in cortical neurons.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Cytoprotection; Dose-Response Relationship, Drug; Galantamine; Glutathione; Lipid Peroxidation; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Peptide Fragments; Plaque, Amyloid; Rats | 2009 |
An unusual case of nightmares with galantamine.
Topics: Aged; Alzheimer Disease; Delayed-Action Preparations; Disease Progression; Dreams; Galantamine; Humans; Male; Neuropsychological Tests; Nootropic Agents | 2009 |
Optimal dosing of galantamine in patients with mild or moderate Alzheimer's disease: post Hoc analysis of a randomized, double-blind, placebo-controlled trial.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Female; Galantamine; Humans; Male; Neuropsychological Tests; Randomized Controlled Trials as Topic; Treatment Outcome | 2009 |
Bullous pemphigoid precipitated by galantamine hydrobromide.
Topics: Aged; Alzheimer Disease; Diagnosis, Differential; Female; Galantamine; Humans; Nootropic Agents; Pemphigoid, Bullous | 2009 |
Effects of cholinesterase inhibition on brain white matter volume in Alzheimer's disease.
Topics: Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Brain Mapping; Cholinesterase Inhibitors; Cytoprotection; Disease Progression; Donepezil; Drug Synergism; Drug Therapy, Combination; Female; Galantamine; Humans; Image Processing, Computer-Assisted; Indans; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated; Neural Pathways; Neuroprotective Agents; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2009 |
Validation of Abeta1-40 administration into mouse cerebroventricles as an animal model for Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Ventricles; Cognition Disorders; Disease Models, Animal; Galantamine; Hippocampus; Injections, Intraventricular; Long-Term Potentiation; Male; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Neurotoxins; Nootropic Agents; Peptide Fragments | 2009 |
Persistence with cholinesterase inhibitor therapy for dementia: an observational administrative health database study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Databases, Factual; Delayed-Action Preparations; Dementia; Donepezil; Follow-Up Studies; Galantamine; Humans; Indans; Medication Adherence; Phenylcarbamates; Piperidines; Rivastigmine | 2009 |
Acetylcholinesterase inhibition and insulin resistance in late onset Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Blood Glucose; Brain; Cholinesterase Inhibitors; Female; Galantamine; Geriatric Assessment; Humans; Insulin Resistance; Male; Mental Status Schedule; Nootropic Agents; Psychometrics | 2009 |
Memogain is a galantamine pro-drug having dramatically reduced adverse effects and enhanced efficacy.
Topics: Acetylcholine; Alzheimer Disease; Animals; Brain; Brain Chemistry; Cholinesterase Inhibitors; Cognition; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ferrets; Galantamine; Gastrointestinal Diseases; Humans; Mice; Scopolamine; Synaptic Transmission; Treatment Outcome | 2010 |
International price comparisons of Alzheimer's drugs: a way to close the affordability gap.
Topics: Aged; Alzheimer Disease; Cross-Cultural Comparison; Developing Countries; Donepezil; Drug Costs; Economics; Galantamine; Humans; Income; Indans; India; Memantine; Mexico; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine; United States | 2009 |
Current treatments of Alzheimer disease: are main caregivers satisfied with the drug treatments received by their patients?
Topics: Aged; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Cross-Sectional Studies; Donepezil; Excitatory Amino Acid Antagonists; Female; Galantamine; Humans; Indans; Male; Memantine; Middle Aged; Neuropsychological Tests; Nootropic Agents; Patient Compliance; Patient Satisfaction; Phenylcarbamates; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Rivastigmine; Socioeconomic Factors; Spain; Surveys and Questionnaires | 2009 |
Cholinesterase inhibitors and incidence of bradycardia in patients with dementia in the veterans affairs new England healthcare system.
Topics: Alzheimer Disease; Bradycardia; Cholinesterase Inhibitors; Cross-Sectional Studies; Dementia; Donepezil; Dose-Response Relationship, Drug; Drug Therapy, Combination; Galantamine; Heart Rate; Hospitals, Veterans; Humans; Incidence; Indans; Massachusetts; Nootropic Agents; Phenylcarbamates; Piperidines; Risk; Rivastigmine; Veterans | 2009 |
Alzheimer's disease: Seeing the signs early.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Disease Progression; Galantamine; Humans; Memantine; Neuroprotective Agents; Nootropic Agents; Phenylcarbamates; Primary Health Care; Psychometrics; Rivastigmine; Time Factors | 2009 |
[The use of galantamine in Alzheimer's disease associated with vascular dementia (according to the study of T. Erkinjuntti group)].
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Data Interpretation, Statistical; Dementia, Vascular; Double-Blind Method; Female; Galantamine; Humans; Male; Middle Aged; Nootropic Agents; Placebos; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Treatment Outcome | 2009 |
Prescribing of drugs for Alzheimer's disease: a South African database analysis.
Topics: Aged; Alzheimer Disease; Cohort Studies; Cost-Benefit Analysis; Costs and Cost Analysis; Donepezil; Drug Prescriptions; Female; Galantamine; Humans; Indans; Male; Memantine; Nootropic Agents; Piperidines; Practice Patterns, Physicians'; Retrospective Studies; South Africa | 2010 |
Effects of donepezil, galantamine and rivastigmine in 938 Italian patients with Alzheimer's disease: a prospective, observational study.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Apolipoproteins E; Cholinesterase Inhibitors; Cognition; Donepezil; Female; Galantamine; Genetic Variation; Genotype; Humans; Indans; Italy; Male; Outcome Assessment, Health Care; Phenylcarbamates; Piperidines; Prospective Studies; Psychiatric Status Rating Scales; Rivastigmine; Severity of Illness Index; Time Factors; Treatment Outcome | 2010 |
Drug treatment of Alzheimer's disease patients leads to expression changes in peripheral blood cells.
Topics: Alzheimer Disease; Analysis of Variance; Blood Cells; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Galantamine; Gene Expression Regulation; Genome-Wide Association Study; Humans; Indans; Microarray Analysis; Phenylcarbamates; Piperidines; Principal Component Analysis; Rivastigmine; RNA | 2010 |
Lower Barthel Index scores predict less prescription of pharmacological therapy in elderly patients with Alzheimer disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Comorbidity; Donepezil; Drug Utilization; Female; Galantamine; Geriatric Assessment; Humans; Indans; Male; Memantine; Middle Aged; Neuropsychological Tests; Nootropic Agents; Phenylcarbamates; Piperidines; Psychiatric Status Rating Scales; Psychotropic Drugs; Rivastigmine; Socioeconomic Factors | 2010 |
Galantamine does not cause aggravated orthostatic hypotension in people with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cholinesterase Inhibitors; Female; Galantamine; Hemodynamics; Humans; Hypotension, Orthostatic; Male; Netherlands; Syncope, Vasovagal | 2010 |
Anticholinesterase duration in the Australian veteran population.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Australia; Cholinesterase Inhibitors; Donepezil; Female; Follow-Up Studies; Galantamine; Humans; Indans; Male; Medication Adherence; Phenylcarbamates; Piperidines; Retrospective Studies; Rivastigmine; Time Factors; Treatment Outcome; Veterans | 2010 |
Comparative effectiveness research: an approach to avoiding "overgeneralized medicine".
Topics: Alzheimer Disease; Clinical Trials as Topic; Comparative Effectiveness Research; Financing, Government; Galantamine; Healthcare Disparities; Humans; Treatment Outcome | 2009 |
Risk factors for nursing home placement in Alzheimer's disease: a longitudinal study of cognition, ADL, service utilization, and cholinesterase inhibitor treatment.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Donepezil; Female; Galantamine; Humans; Indans; Kaplan-Meier Estimate; Male; Middle Aged; Nursing Homes; Phenylcarbamates; Piperidines; Proportional Hazards Models; Prospective Studies; Risk Factors; Rivastigmine; Severity of Illness Index; Sex Factors; Sweden | 2011 |
The dramatic effects of Galantamine in a patient with early-onset Alzheimer's disease.
Topics: Alzheimer Disease; England; Female; Follow-Up Studies; Galantamine; Humans; Mental Status Schedule; Middle Aged; Nootropic Agents; State Medicine | 2010 |
Predictors of adherence among Alzheimer's disease patients receiving oral therapy.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Donepezil; Dopamine Agents; Female; Galantamine; Humans; Indans; Insurance Claim Review; Logistic Models; Male; Medication Adherence; Memantine; Neuroprotective Agents; Nootropic Agents; Phenylcarbamates; Piperidines; Predictive Value of Tests; Retrospective Studies; Rivastigmine; Treatment Outcome | 2010 |
[Variability and trends in dementia drug consumption in Castile-La Mancha (Spain). Estimated prevalence of Alzheimer's disease].
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dopamine Agents; Galantamine; Ginkgo biloba; Humans; Indans; Memantine; Neuroprotective Agents; Nootropic Agents; Observer Variation; Phenylcarbamates; Piperidines; Plant Extracts; Rivastigmine; Spain; Substance-Related Disorders | 2010 |
Discontinuation of cholinesterase inhibitor treatment and determinants thereof in the Netherlands: A retrospective cohort study.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Dose-Response Relationship, Drug; Female; Galantamine; Humans; Medication Adherence; Netherlands; Phenylcarbamates; Retrospective Studies; Rivastigmine | 2010 |
Galantamine inhibits calpain-calcineurin signaling activated by beta-amyloid in human neuroblastoma SH-SY5Y cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Calcineurin; Calcineurin Inhibitors; Calpain; Cell Line, Tumor; Cholinesterase Inhibitors; Galantamine; Humans; Nerve Degeneration; Neuroblastoma; Peptide Fragments; Signal Transduction | 2010 |
Prescribing trends in cognition enhancing drugs in Australia.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Australia; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Humans; Indans; Male; Memantine; Middle Aged; Nootropic Agents; Piperidines; Practice Patterns, Physicians'; Sex Factors | 2011 |
Galantamine-induced amyloid-{beta} clearance mediated via stimulation of microglial nicotinic acetylcholine receptors.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies, Monoclonal; Binding Sites; Calcium Signaling; Calmodulin; Cells, Cultured; Choline; Cholinesterase Inhibitors; Disease Models, Animal; Female; Galantamine; Hippocampus; Humans; Male; Microglia; Nootropic Agents; Phagocytosis; Rats; Rats, Wistar; Receptors, Nicotinic | 2010 |
Modelling the clinical and economic implications of galantamine in the treatment of mild-to-moderate Alzheimer's disease in Germany.
Topics: Aged, 80 and over; Alzheimer Disease; Caregivers; Disease Progression; Female; Galantamine; Germany; Ginkgo biloba; Humans; Long-Term Care; Male; Models, Economic; Nootropic Agents; Severity of Illness Index | 2010 |
Long-term response to galantamine in relation to short-term efficacy data: pooled analysis in patients with mild to moderate Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Galantamine; Humans; Randomized Controlled Trials as Topic; Treatment Outcome | 2011 |
Beneficial effect of repetitive transcranial magnetic stimulation combined with cognitive training for the treatment of Alzheimer's disease: a proof of concept study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Female; Galantamine; Humans; Male; Middle Aged; Practice, Psychological; Psychiatric Status Rating Scales; Transcranial Magnetic Stimulation; Treatment Outcome | 2011 |
Stability-indicating study of the anti-Alzheimer's drug galantamine hydrobromide.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cholinesterases; Chromatography, High Pressure Liquid; Drug Stability; Galantamine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Light; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Photolysis; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry; Technology, Pharmaceutical | 2011 |
Cardio-vascular safety of acetyl cholinesterase inhibitors in patients suffering from Alzheimer's disease; factors that predict poor tolerability.
Topics: Alzheimer Disease; Cardiovascular Diseases; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Multivariate Analysis; Phenylcarbamates; Piperidines; Retrospective Studies; Rivastigmine | 2011 |
[Prescription differences of dementia drugs in urban and rural areas in Germany].
Topics: Aged; Alzheimer Disease; Ambulatory Care; Donepezil; Galantamine; General Practice; Germany; Humans; Indans; Medically Underserved Area; Memantine; Neuropsychiatry; Nootropic Agents; Phenylcarbamates; Piperidines; Practice Patterns, Physicians'; Rivastigmine; Rural Population; Urban Population; Workforce | 2011 |
BCHE and CYP2D6 genetic variation in Alzheimer's disease patients treated with cholinesterase inhibitors.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Butyrylcholinesterase; Cholinesterase Inhibitors; Cognition; Cytochrome P-450 CYP2D6; Donepezil; Female; Galantamine; Genetic Association Studies; Genetic Variation; Genotype; Humans; Indans; Male; Middle Aged; Phenylcarbamates; Piperidines; Rivastigmine; Treatment Outcome | 2011 |
Oral tremor induced by galantamine in rats: a model of the parkinsonian side effects of cholinomimetics used to treat Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cholinergic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Galantamine; Jaw; Male; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tremor | 2011 |
Bradycardia due to cholinesterase inhibitors: identify adverse effects and take them into account.
Topics: Alzheimer Disease; Bradycardia; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Risk; Rivastigmine | 2011 |
Alkaloids from Hippeastrum papilio.
Topics: Alkaloids; Alzheimer Disease; Cholinesterase Inhibitors; Cholinesterases; Chromatography, Thin Layer; Galantamine; Humans; Liliaceae; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves | 2011 |
Drugs for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Drug Design; Excitatory Amino Acid Antagonists; Galantamine; Humans; Memantine; Plaque, Amyloid | 2012 |
Antioxidant enzymatic activities in Alzheimer's disease: the relationship to acetylcholinesterase inhibitors.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Catalase; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Glutathione Reductase; Humans; Indans; Male; Oxidative Stress; Phenylcarbamates; Piperidines; Rivastigmine | 2012 |
[New anti-AD drugs--their possibilities and issues].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans; Memantine; N-Methylaspartate; Phenylcarbamates; Rivastigmine | 2012 |
Which cholinesterase inhibitor is the safest for the heart in elderly patients with Alzheimer's disease?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood Pressure; Cholinesterase Inhibitors; Donepezil; Female; Galantamine; Heart; Humans; Indans; Male; Phenylcarbamates; Piperidines; Rivastigmine | 2012 |
[Galantamine].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans | 2011 |
Combination therapy with galantamine and memantine improves behavioral and psychological symptoms of dementia (BPSD) in patients with early-onset Alzheimer's disease.
Topics: Alzheimer Disease; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Galantamine; Humans; Memantine; Middle Aged; Parasympathomimetics | 2013 |
Use of rivastigmine or galantamine and risk of adverse cardiac events: a database study from the Netherlands.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atrioventricular Block; Cholinesterase Inhibitors; Cohort Studies; Cross-Over Studies; Databases, Factual; Female; Galantamine; Hospitalization; Humans; Incidence; Male; Netherlands; Phenylcarbamates; Poisson Distribution; Proportional Hazards Models; Risk; Rivastigmine; Syncope | 2012 |
Protective effect of galantamine against oxidative damage using human lymphocytes: a novel in vitro model.
Topics: Alzheimer Disease; Apoptosis; Cell Culture Techniques; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Galantamine; Humans; Hydrogen Peroxide; Lymphocytes; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2013 |
Assessment of Health Economics in Alzheimer's Disease (AHEAD): treatment with galantamine in Sweden.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Clinical Trials as Topic; Cost of Illness; Disease Progression; Drug Costs; Galantamine; Health Care Costs; Health Services Needs and Demand; Health Services Research; Humans; Institutionalization; Long-Term Care; Models, Econometric; Nootropic Agents; Probability; Sensitivity and Specificity; Sweden | 2002 |
Economic analysis of galantamine, a cholinesterase inhibitor, in the treatment of patients with mild to moderate Alzheimer's disease in the Netherlands.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Health Care Costs; Humans; Models, Economic; Netherlands; Nursing Homes; Prognosis; Severity of Illness Index | 2002 |
Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antibodies; Choline O-Acetyltransferase; Cholinergic Agonists; Disease Models, Animal; Entorhinal Cortex; Galantamine; Humans; Mice; Mice, Knockout; Mice, Transgenic; Nerve Degeneration; Nerve Growth Factor; Phenotype; Phosphorylation; Recombinant Proteins; tau Proteins | 2002 |
Broad therapeutic benefits in patients with probable vascular dementia or Alzheimer's disease with cerebrovascular disease after treatment with galantamine.
Topics: Activities of Daily Living; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Dementia, Vascular; Galantamine; Humans; Treatment Outcome | 2002 |
Galantamine provides broad benefits in patients with 'advanced moderate' Alzheimer's disease (MMSE < or = 12) for up to six months.
Topics: Aged; Alzheimer Disease; Behavior; Cholinesterase Inhibitors; Chronic Disease; Clinical Trials, Phase III as Topic; Cognition; Female; Galantamine; Humans; Male; Nootropic Agents; Randomized Controlled Trials as Topic; Treatment Outcome | 2002 |
The impact of journal advertisements on prescribers of cholinesterase inhibitors.
Topics: Advertising; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Donepezil; Drug Prescriptions; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Publishing; Random Allocation; Rivastigmine | 2002 |
Galantamine: a pharmacoeconomic review of its use in Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Costs and Cost Analysis; Galantamine; Humans | 2002 |
[Galantamine: a novel cholinergic agent for Alzheimer's disease].
Topics: Acetylcholine; Allosteric Regulation; Alzheimer Disease; Cell Line; Cholinesterase Inhibitors; Cognition; Galantamine; Humans; Molecular Structure; Parasympathomimetics; Treatment Outcome | 2002 |
Patterns of clinically detectable treatment effects with galantamine: a qualitative analysis.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Clinical Trials, Phase III as Topic; Double-Blind Method; Female; Galantamine; Humans; Interview, Psychological; Male; Middle Aged; Multicenter Studies as Topic; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Treatment Outcome | 2003 |
Broad therapeutic benefits in patients with probable vascular dementia or Alzheimer's disease with cerebrovascular disease treated with galantamine.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dementia, Vascular; Galantamine; Humans; Phytotherapy; Research Design; Time Factors | 2002 |
Acetylcholinesterase inhibitors for vascular dementia and Alzheimer's disease combined with cerebrovascular disease.
Topics: Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition Disorders; Dementia, Vascular; Diagnosis, Differential; Donepezil; Galantamine; Humans; Indans; Neuropsychological Tests; Nootropic Agents; Piperidines; Severity of Illness Index; Terminology as Topic; Treatment Outcome | 2003 |
Sequential designs for phase III clinical trials incorporating treatment selection.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cognition; Computer Simulation; Data Interpretation, Statistical; Drug Approval; Galantamine; Humans; Research Design | 2003 |
[Early diagnosis and treatment of Alzheimer's disease. Implementation in the doctor's office].
Topics: Aged; Alzheimer Disease; Brief Psychiatric Rating Scale; Carbamates; Cholinesterase Inhibitors; Dihydroergotoxine; Donepezil; Family Practice; Female; Follow-Up Studies; Galantamine; Ginkgo biloba; Humans; Indans; Male; Memantine; Neuroprotective Agents; Nimodipine; Nootropic Agents; Phenylcarbamates; Piperidines; Piracetam; Psychiatric Status Rating Scales; Risk Factors; Rivastigmine; Time Factors; Vasodilator Agents | 2002 |
Galantamine population pharmacokinetics in patients with Alzheimer's disease: modeling and simulations.
Topics: Adult; Aged; Algorithms; Alzheimer Disease; Bayes Theorem; Cholinesterase Inhibitors; Clinical Trials as Topic; Computer Simulation; Dose-Response Relationship, Drug; Female; Galantamine; Humans; Liver Diseases; Male; Middle Aged; Models, Biological; Population; Reproducibility of Results; Sex Characteristics; Software | 2003 |
Galantamine.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Drug Approval; Galantamine; Humans; Israel | 2003 |
Clinical experience of galantamine in dementia: a series of case reports.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Female; Galantamine; Humans; Male; Middle Aged; Nootropic Agents | 2003 |
Galantamine vs donepezil in the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Galantamine; Humans; Indans; Piperidines | 2003 |
Pharmacologic treatment expectations in the management of dementia with Lewy bodies.
Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Brain; Carbamates; Cholinesterase Inhibitors; Diagnosis, Differential; Donepezil; Galantamine; Humans; Indans; Lewy Body Disease; Nootropic Agents; Phenylcarbamates; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Treatment Outcome | 2004 |
A case history illustrating how extended release cholinesterase inhibitors could improve management of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Rivastigmine | 2003 |
Anticholinesterases in Alzheimer's disease: a modest effect on moderately severe disease.
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; France; Galantamine; Humans; Indans; Piperidines; Product Surveillance, Postmarketing; Randomized Controlled Trials as Topic; Tacrine; Treatment Outcome | 2003 |
A 6-month open-label study of the effectiveness and tolerability of galantamine in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Galantamine; Humans; Male; Middle Aged; Nootropic Agents; Treatment Outcome | 2004 |
[Acetylcholinesterase inhibitors].
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Galantamine; Humans; Phenylcarbamates; Rivastigmine | 2003 |
Drug therapy for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans | 2004 |
Examination of nighttime sleep-related problems during double-blind, placebo-controlled trials of galantamine in patients with Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Dreams; Galantamine; Humans; Nootropic Agents; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders | 2004 |
Effects of galantamine on behavioural and psychological disturbances and caregiver burden in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Caregivers; Female; Galantamine; Humans; Male; Mental Disorders; Middle Aged; Nootropic Agents; Switzerland | 2004 |
Understanding the latest advances in pharmacologic interventions for Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Antioxidants; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Drug Therapy, Combination; Galantamine; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Piperidines; Receptors, N-Methyl-D-Aspartate; Rivastigmine; Treatment Outcome | 2004 |
Assessing the health and economic impact of galantamine treatment in patients with Alzheimer's disease in the health care systems of different countries.
Topics: Alzheimer Disease; Australasia; Canada; Cost-Benefit Analysis; Delivery of Health Care; Europe; Galantamine; Humans; Long-Term Care; Models, Economic; Placebos | 2004 |
Cholinergic drugs for Alzheimer's disease enhance in vitro dopamine release.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinergic Agents; Cholinesterase Inhibitors; Donepezil; Dopamine; Dose-Response Relationship, Drug; Galantamine; Indans; Mice; Piperidines; Receptors, Nicotinic | 2004 |
Different TMS patterns of intracortical inhibition in early onset Alzheimer dementia and frontotemporal dementia.
Topics: Aged; Alzheimer Disease; Brain; Cholinesterase Inhibitors; Dementia; Electromagnetic Fields; Electromyography; Evoked Potentials, Motor; Female; Frontal Lobe; Functional Laterality; Galantamine; Humans; Male; Middle Aged; Neuroprotective Agents; Temporal Lobe | 2004 |
Reversible Pisa syndrome (pleurothotonus) due to the cholinesterase inhibitor galantamine: case report.
Topics: Aged; Alzheimer Disease; Botulinum Toxins, Type A; Cholinesterase Inhibitors; Cognition Disorders; Dystonia; Female; Galantamine; Humans; Neuromuscular Agents; Neuropsychological Tests; Severity of Illness Index; Syndrome | 2004 |
Switching from donepezil or rivastigmine to galantamine in clinical practice.
Topics: Alzheimer Disease; Donepezil; Galantamine; Humans; Indans; Neuroprotective Agents; Nootropic Agents; Phenylcarbamates; Piperidines; Retrospective Studies; Rivastigmine | 2004 |
Not all head-to-head trials are created equal: results from an open-label, short-term study seem inconsistent with previous donepezil literature.
Topics: Aged; Alzheimer Disease; Caregivers; Cognition; Donepezil; Galantamine; Humans; Indans; Nootropic Agents; Piperidines; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome | 2005 |
Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cholinesterase Inhibitors; Cognition; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Galantamine; Humans; Indans; Male; Memantine; Mice; Mice, Mutant Strains; Phenylcarbamates; Piperidines; Rivastigmine; Sensitivity and Specificity | 2005 |
Differential effect of PMS777, a new type of acetylcholinesterase inhibitor, and galanthamine on oxidative injury induced in human neuroblastoma SK-N-SH cells.
Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Encephalitis; Furans; Galantamine; Glutathione; Humans; Inflammation Mediators; Interleukin-1; Lipopolysaccharides; Mitochondria; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Platelet Activating Factor; Reactive Oxygen Species | 2005 |
Cognitive evaluation of disease-modifying efficacy of galantamine and memantine in the APP23 model.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Cholinesterase Inhibitors; Cognition; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Excitatory Amino Acid Antagonists; Galantamine; Humans; Maze Learning; Memantine; Mice; Mice, Transgenic; Motor Activity; Neuropsychological Tests; Random Allocation; Reaction Time; Time Factors | 2006 |
UK government guidance on Alzheimer's drugs postponed.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cost-Benefit Analysis; Donepezil; Excitatory Amino Acid Antagonists; Federal Government; Galantamine; Government Regulation; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine; United Kingdom | 2005 |
Galantamine in the treatment of vascular dementia.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Dementia, Vascular; Galantamine; Humans | 2003 |
Early onset effects of galantamine treatment on attention in patients with Alzheimer's disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Attention; Caregivers; Cholinesterase Inhibitors; Europe; Female; Galantamine; Humans; Male; Middle Aged; Treatment Outcome | 2005 |
Cholinergic challenge in Alzheimer patients and mild cognitive impairment differentially affects hippocampal activation--a pharmacological fMRI study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Case-Control Studies; Chi-Square Distribution; Cholinesterase Inhibitors; Cognition Disorders; Female; Galantamine; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests | 2006 |
Behavioral and neuropsychiatric outcomes in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Brain; Diagnostic and Statistical Manual of Mental Disorders; Galantamine; Humans; Mental Disorders; Phenylcarbamates; Prevalence; Rivastigmine | 2005 |
A case report of paranoid delusion with galantamine use.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Delusions; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Galantamine; Humans; Male; Paranoid Disorders; Recurrence | 2005 |
An innovative approach to involve patients in measuring treatment effects in drug trials.
Topics: Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Endpoint Determination; Galantamine; Goals; Humans; Psychometrics; Randomized Controlled Trials as Topic; Treatment Outcome | 2006 |
[Complete atrioventricular block during galantamine therapy].
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Electrocardiography; Galantamine; Heart Block; Humans; Male; Pacemaker, Artificial | 2006 |
[Use of reminyl (galantamine) in the treatment of dementia].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Dementia; Dementia, Vascular; Female; Galantamine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Time Factors; Treatment Outcome | 2006 |
Alzheimer's disease: beware of interactions with cholinesterase inhibitors.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dopamine Agonists; Drug Interactions; Galantamine; Humans; Indans; Memantine; Phenylcarbamates; Piperidines; Treatment Outcome | 2006 |
Once-daily formulation of galantamine.
Topics: Aged; Alzheimer Disease; Chemistry, Pharmaceutical; Cholinesterase Inhibitors; Delayed-Action Preparations; Galantamine; Humans; Nursing Homes; Patient Selection; Severity of Illness Index | 2006 |
[Advances in Alzheimer's disease treatment].
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Clinical Trials, Phase III as Topic; Donepezil; Excitatory Amino Acid Antagonists; Galantamine; Humans; Indans; Memantine; Multicenter Studies as Topic; Neuroprotective Agents; Nootropic Agents; Phenylcarbamates; Piperidines; Placebos; Randomized Controlled Trials as Topic; Rivastigmine | 2006 |
Comparative analysis of mortality in patients with Alzheimer's disease treated with donepezil or galantamine.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chi-Square Distribution; Cholinesterase Inhibitors; Cohort Studies; Comorbidity; Donepezil; Female; Galantamine; Humans; Indans; Male; Middle Aged; Piperidines; Retrospective Studies; Treatment Outcome | 2006 |
[Pharmacotherapy of a patient with Alzheimer's disease: interactions with the antidementive galantamine].
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Drug Interactions; Female; Galantamine; Humans; Nootropic Agents | 2006 |
[Cholinesterase inhibitor therapy in long term care settings].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Follow-Up Studies; Galantamine; Humans; Indans; Long-Term Care; Neuroprotective Agents; Nootropic Agents; Patient Selection; Phenylcarbamates; Piperidines; Retrospective Studies; Rivastigmine; Time Factors | 2006 |
Position statement of the American Association for Geriatric Psychiatry regarding principles of care for patients with dementia resulting from Alzheimer disease.
Topics: Aged; Alkaloids; Alzheimer Disease; Brain; Caregivers; Cholinesterase Inhibitors; Cognition Disorders; Dementia; Diagnostic and Statistical Manual of Mental Disorders; Galantamine; Geriatric Psychiatry; Health Services for the Aged; Humans; Phenylcarbamates; Professional-Family Relations; Rivastigmine; Sesquiterpenes; Tacrine; United States | 2006 |
Patterns of cholinesterase-inhibitor use in the nursing home setting: a retrospective analysis.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Utilization; Female; Galantamine; Homes for the Aged; Humans; Indans; Male; Middle Aged; Nursing Homes; Phenylcarbamates; Piperidines; Polypharmacy; Retrospective Studies; Rivastigmine | 2006 |
Galantamine extended release.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Drug Administration Routes; Drug Administration Schedule; Galantamine; Humans; Inhibitory Concentration 50 | 2006 |
[Mortality-associated factors in patients with Alzheimer's disease treated with galantamine].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Female; Galantamine; Humans; Male; Retrospective Studies | 2006 |
Adjuvant galantamine for cognitive dysfunction in a patient with bipolar disorder.
Topics: Alzheimer Disease; Antimanic Agents; Bipolar Disorder; Cholinesterase Inhibitors; Cognition Disorders; Diagnosis, Differential; Female; Galantamine; Humans; Middle Aged; Neuropsychological Tests; Severity of Illness Index | 2006 |
In vitro galantamine-memantine co-application: mechanism of beneficial action.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Bicuculline; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Drug Evaluation, Preclinical; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Galantamine; Glycine; In Vitro Techniques; Inhibitory Concentration 50; Memantine; Nerve Tissue Proteins; Neuroprotective Agents; Nicotinic Agonists; Patch-Clamp Techniques; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Strychnine; Synaptic Transmission; Therapeutic Irrigation | 2006 |
[Complete atrioventricular block during galantamine therapy].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Heart Block; Humans; Quality of Life | 2006 |
Effects of statins on cognitive function in patients with Alzheimer's disease in galantamine clinical trials.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Galantamine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nootropic Agents | 2007 |
Comparative analysis of mortality in patients with Alzheimer's disease treated with donepezil and galantamine.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Nootropic Agents; Piperidines | 2007 |
Galantamine and QTc prolongation.
Topics: Alzheimer Disease; Arrhythmias, Cardiac; Cholinesterase Inhibitors; Galantamine; Humans; Long QT Syndrome; Schizophrenia; Sick Sinus Syndrome | 2007 |
Evaluation of the slopes of cognitive impairment and disability in Alzheimer's disease (AD) patients treated with acetylcholinesterase inhibitors (AChEl).
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Diagnostic and Statistical Manual of Mental Disorders; Disability Evaluation; Donepezil; Female; Follow-Up Studies; Galantamine; Humans; Indans; Male; Mental Disorders; Neuropsychological Tests; Phenylcarbamates; Piperidines; Rivastigmine; Severity of Illness Index | 2007 |
Anti-Alzheimer drugs: life-threatening adverse effects.
Topics: Alzheimer Disease; Cardiovascular Diseases; Cholinesterase Inhibitors; France; Galantamine; Humans; Indans; Memantine; Phenylcarbamates; Piperidines | 2007 |
Galantamine for Alzheimer's disease and mild cognitive impairment.
Topics: Alzheimer Disease; Cognition Disorders; Delayed-Action Preparations; Galantamine; Humans; Nootropic Agents; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Treatment Outcome | 2007 |
Regional brain activity after prolonged cholinergic enhancement in early Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Brain Mapping; Cholinergic Agents; Dementia; Female; Galantamine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Parasympathomimetics; Reproducibility of Results | 2007 |
Competitive antagonism between the nicotinic allosteric potentiating ligand galantamine and kynurenic acid at alpha7* nicotinic receptors.
Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Atropine; Cells, Cultured; Choline; Corpus Striatum; Dopamine; Galantamine; Kynurenic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2007 |
Patterns of decline and evidence of subgroups in patients with Alzheimer's disease taking galantamine for up to 48 months.
Topics: Aged; Alzheimer Disease; Canada; Cholinesterase Inhibitors; Cognition; Disease Progression; Europe; Female; Follow-Up Studies; Galantamine; Humans; Logistic Models; Male; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Treatment Outcome | 2008 |
Acetylcholinesterase inhibitors in assisted living: patterns of use and association with retention.
Topics: Activities of Daily Living; Aged, 80 and over; Alzheimer Disease; Assisted Living Facilities; Cholinesterase Inhibitors; Dementia; Donepezil; Drug Administration Schedule; Female; Galantamine; Health Surveys; Homes for the Aged; Humans; Indans; Male; Mental Status Schedule; Neuropsychological Tests; Phenylcarbamates; Piperidines; Retention, Psychology; Rivastigmine; Survival Analysis; Treatment Outcome | 2008 |
Effect of galantamine on verbal repetition in AD: a secondary analysis of the VISTA trial.
Topics: Alzheimer Disease; Caregivers; Clinical Trials as Topic; Disability Evaluation; Galantamine; Humans; Memory Disorders; Neuropsychological Tests; Nootropic Agents; Outcome Assessment, Health Care; Quality of Life; Respiratory Tract Infections; Risk Assessment; Speech Disorders; Treatment Outcome; Verbal Behavior; Vomiting | 2007 |
A rabbit model of Alzheimer's disease: valid at neuropathological, cognitive, and therapeutic levels.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blinking; Cerebellum; Cholinesterase Inhibitors; Cognition Disorders; Conditioning, Classical; Disease Models, Animal; Galantamine; Hippocampus; Male; Neurons; Neuropsychological Tests; Rabbits; tau Proteins | 2007 |
NICE judgement leaves behind a nasty taste.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Disease Progression; Donepezil; Formularies as Topic; Galantamine; Humans; Indans; Insurance, Health, Reimbursement; Insurance, Pharmaceutical Services; Jurisprudence; Phenylcarbamates; Piperidines; Rivastigmine; State Medicine; Time Factors; United Kingdom | 2007 |
[Alzheimer drugs for mild cognitive impairment].
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Early Diagnosis; Galantamine; Humans; Memantine; Neuropsychological Tests; Nootropic Agents; Treatment Failure | 2007 |
Cholinesterase inhibitors: tremor and exacerbation of Parkinson's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Dementia; Dystonia; France; Galantamine; Humans; Indans; Lewy Body Disease; Parkinson Disease; Phenylcarbamates; Piperidines; Tremor | 2007 |
Influence of galantamine on vasomotor reactivity in Alzheimer's disease and vascular dementia due to cerebral microangiopathy.
Topics: Acetylcholinesterase; Adult; Aged; Alzheimer Disease; Carbon Dioxide; Case-Control Studies; Cerebrovascular Disorders; Cholinesterase Inhibitors; Dementia, Vascular; Female; Galantamine; Humans; Male; Middle Aged; Nervous System; Spectroscopy, Near-Infrared; Ultrasonography, Doppler | 2007 |
Risperidone, olanzapine and quetiapine in the treatment of behavioral and psychological symptoms in patients with Alzheimer's disease: preliminary findings from a naturalistic, retrospective study.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Antipsychotic Agents; Behavior; Benzodiazepines; Cognition; Data Interpretation, Statistical; Dibenzothiazepines; Donepezil; Endpoint Determination; Female; Galantamine; Humans; Indans; Long-Term Care; Male; Neuropsychological Tests; Nootropic Agents; Olanzapine; Phenylcarbamates; Piperidines; Psychiatric Status Rating Scales; Quetiapine Fumarate; Retrospective Studies; Risperidone; Rivastigmine; Treatment Outcome | 2007 |
For debate: is the evidence for the efficacy of cholinesterase inhibitors in the symptomatic treatment of Alzheimer's disease convincing or not?
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Galantamine; Humans; Indans; Neuropsychological Tests; Piperidines; Severity of Illness Index; Treatment Outcome | 2008 |
Treatment for MCI: is the evidence sufficient?
Topics: Alzheimer Disease; Clinical Trials as Topic; Cognition Disorders; Galantamine; Humans | 2008 |
Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Body Temperature; Cholinesterase Inhibitors; Galantamine; Humans; Male; Mice; Rats; Rats, Sprague-Dawley; Rats, Wistar; Scopolamine | 1996 |
[Neuroprotective therapy of Alzheimer's disease?].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans; Neuroprotective Agents; Physostigmine; Piracetam; Tacrine | 1996 |
Evaluation of four Narcissus cultivars as potential sources for galanthamine production.
Topics: Alzheimer Disease; Galantamine; Humans; Plant Roots; Plants, Medicinal | 1997 |
Enantiomeric resolution of galanthamine and related drugs used in anti-Alzheimer therapy by means of capillary zone electrophoresis employing derivatized cyclodextrin selectors.
Topics: Alzheimer Disease; Electrophoresis, Capillary; Galantamine; Galanthus; Humans; Nootropic Agents; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism | 1999 |
Capillary zone electrophoresis determination of galanthamine in biological fluids and pharmaceutical preparatives: experimental design and artificial neural network optimization.
Topics: Alzheimer Disease; Body Fluids; Cholinesterase Inhibitors; Electrophoresis, Capillary; Galantamine; Humans; Hydrogen-Ion Concentration; Neural Networks, Computer; Pharmaceutical Preparations; Regression Analysis; Reproducibility of Results | 1999 |
Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease.
Topics: Allosteric Regulation; Alzheimer Disease; Animals; Cells, Cultured; Cholinergic Agents; Cholinesterase Inhibitors; Cognition; Galantamine; Humans; Learning; Neurotransmitter Agents; PC12 Cells; Rats; Receptors, Nicotinic | 2000 |
The sensitivity to change over time of the Bristol Activities of Daily Living Scale in Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Clinical Trials as Topic; Female; Galantamine; Humans; Male; Mental Status Schedule; Middle Aged; Nootropic Agents; Psychiatric Status Rating Scales; Psychometrics; Reproducibility of Results; Sensitivity and Specificity; Tacrine | 2000 |
Nicotinic modulation in an animal model of a form of associative learning impaired in Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Animals; Association Learning; Cholinesterase Inhibitors; Conditioning, Classical; Conditioning, Eyelid; Disease Models, Animal; Female; Galantamine; Humans; Mental Recall; Nootropic Agents; Rabbits; Receptors, Nicotinic | 2000 |
The new cholinesterase inhibitors for Alzheimer's disease, Part 1: their similarities are different.
Topics: Aged; Alzheimer Disease; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Receptors, Nicotinic; Rivastigmine; Tacrine | 2000 |
The new cholinesterase inhibitors for Alzheimer's disease, Part 2: illustrating their mechanisms of action.
Topics: Alzheimer Disease; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Receptors, Nicotinic; Rivastigmine | 2000 |
[Treatment of the elderly dementia patients].
Topics: Aged; Alzheimer Disease; Benzazepines; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Piperidines; Tacrine; Trichlorfon | 2000 |
FDA approves galantamine for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Drug Approval; Galantamine; Humans; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration | 2001 |
Therapeutic continuity in Alzheimer's disease: switching patients to galantamine. Introduction.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans | 2001 |
Pharmacokinetic profiles of current therapies for Alzheimer's disease: implications for switching to galantamine.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Donepezil; Drug Interactions; Galantamine; Humans; Indans; Phenylcarbamates; Piperidines; Rivastigmine; Sleep | 2001 |
Effects of washout and dose-escalation periods on the efficacy, safety, and tolerability of galantamine in patients previously treated with donepezil: ongoing clinical trials.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Drug Administration Schedule; Galantamine; Humans; Indans; Piperidines | 2001 |
Switching previous therapies for Alzheimer's disease to galantamine.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Galantamine; Humans | 2001 |
Therapeutic continuity in Alzheimer's disease: switching patients to galantamine. Panel discussion: recommendations for prescribers.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans | 2001 |
Pharmacokinetic rationale for switching from donepezil to galantamine.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Models, Biological; Piperidines | 2001 |
Meeting the challenges of vascular dementia. Introduction.
Topics: Alzheimer Disease; Dementia, Vascular; Galantamine; Humans; Nootropic Agents | 2001 |
Galantamine (reminyl) for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Diarrhea; Dizziness; Dose-Response Relationship, Drug; Galantamine; Humans; Nausea; Vomiting | 2001 |
Accurate prediction of the bound conformation of galanthamine in the active site of Torpedo californica acetylcholinesterase using molecular docking.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Catalytic Domain; Cholinesterase Inhibitors; Computer Simulation; Crystallography, X-Ray; Galantamine; Humans; Models, Molecular; Molecular Conformation; Nootropic Agents; Protein Conformation; Software; Torpedo | 2001 |
Featured CME topic: dementia. Medication update.
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Contraindications; Donepezil; Drug Interactions; Ergoloid Mesylates; Galantamine; Ginkgo biloba; Humans; Indans; Nootropic Agents; Phenylcarbamates; Phytotherapy; Piperidines; Plants, Medicinal; Rivastigmine | 2001 |
Assessment of health economics in Alzheimer's disease (AHEAD): galantamine treatment in Canada.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Canada; Clinical Trials as Topic; Cost Control; Disease Progression; Female; Galantamine; Health Services Needs and Demand; Humans; Long-Term Care; Male; Models, Economic; Nootropic Agents | 2001 |
The snowdrop (Galanthus nivalis): from Odysseus to Alzheimer.
Topics: Alzheimer Disease; Botany; Folklore; Galantamine; Galanthus; History, Ancient; History, Modern 1601-; Humans | 1999 |
Maintaining cognitive function in Alzheimer disease: how effective are current treatments?
Topics: Aged; Alzheimer Disease; Clinical Trials as Topic; Galantamine; Humans; Neuropsychological Tests; Nootropic Agents; Treatment Outcome | 2001 |
Modulation of nicotinic receptor activity in the central nervous system: a novel approach to the treatment of Alzheimer disease.
Topics: Acetylcholine; Activities of Daily Living; Aged; Alzheimer Disease; Animals; Brain; Clinical Trials as Topic; Galantamine; Humans; Neuropsychological Tests; Nootropic Agents; Receptors, Nicotinic | 2001 |
Maintaining functional and behavioral abilities in Alzheimer disease.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Galantamine; Humans; Indans; Neuropsychological Tests; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine; Tacrine; Treatment Outcome | 2001 |
Galantamine hydrobromide.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Drug Interactions; Galantamine; Humans | 2001 |
Unsafe prescription medication switching recommendations.
Topics: Alzheimer Disease; Donepezil; Drug Interactions; Galantamine; Humans; Indans; Nootropic Agents; Piperidines | 2001 |
[Alzheimer dementia. Comparison of the effectiveness of cholinesterase inhibitors and gingko].
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Confidence Intervals; Donepezil; Galantamine; Ginkgo biloba; Humans; Indans; Neuroprotective Agents; Nootropic Agents; Parasympathomimetics; Phenylcarbamates; Phytotherapy; Piperidines; Placebos; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Rivastigmine | 2001 |
Galantamine: new preparation. The fourth cholinesterase inhibitor for Alzheimer's disease.
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; France; Galantamine; Indans; Tacrine; Treatment Outcome | 2001 |
Pharmacokinetics and safety of galantamine in subjects with hepatic impairment and healthy volunteers.
Topics: Adolescent; Adult; Aged; Alzheimer Disease; Analysis of Variance; Area Under Curve; Cholinesterase Inhibitors; Female; Galantamine; Humans; Liver Diseases; Male; Middle Aged; Protein Binding; Statistics, Nonparametric | 2002 |
Galantamine for vascular dementia: some answers, some questions.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Dementia, Vascular; Galantamine; Humans; Treatment Outcome | 2002 |
Stereoselectivity of cholinesterase inhibition by galanthamine and tolerance in humans.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Female; Galantamine; Humans; Male; Stereoisomerism; Structure-Activity Relationship | 1990 |
Selective inhibition of human acetylcholinesterase by galanthamine in vitro and in vivo.
Topics: Administration, Oral; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Erythrocytes; Galantamine; Galanthus; Humans; In Vitro Techniques | 1990 |