galanin-like-peptide has been researched along with Fibrosis* in 1 studies
1 other study(ies) available for galanin-like-peptide and Fibrosis
Article | Year |
---|---|
Alarin alleviated cardiac fibrosis via attenuating oxidative stress in heart failure rats.
The present study was to explore whether alarin could alleviate heart failure (HF) and attenuate cardia fibrosis via inhibiting oxidative stress. The fibrosis of cardiac fibroblasts (CFs) was induced by angiotensin (Ang) II. HF models were induced by ligation of the left anterior descending artery to cause ischemia myocardial infarction (MI) in Sprague-Dawley rats. Alarin (1.0 nM/kg/d) was administrated by intraperitoneal injection for 28 days. The decreases of left ventricular (LV) ejection fraction (EF), fractional shortening (FS), the maximum of the first differentiation of LV pressure (LV ± dp/dt Topics: Angiotensin II; Animals; Fibrosis; Galanin-Like Peptide; Heart Failure; Male; Malondialdehyde; Myocardial Infarction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Vasoconstrictor Agents | 2021 |