galactose has been researched along with Cataract in 436 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 272 (62.39) | 18.7374 |
1990's | 102 (23.39) | 18.2507 |
2000's | 31 (7.11) | 29.6817 |
2010's | 23 (5.28) | 24.3611 |
2020's | 8 (1.83) | 2.80 |
Authors | Studies |
---|---|
Arai-Ichinoi, N; Kikuchi, A; Kure, S; Wada, Y | 1 |
Jee, D; Kang, S; Park, S | 1 |
Daenzer, JMI; Fridovich-Keil, JL; McKenna, J; Patel, S; Rasmussen, SA | 1 |
Inatani, M; Kanada, F; Nagaya, M; Oki, M; Takamura, Y; Takashima, M | 1 |
Inatani, M; Kanada, F; Nagaya, M; Oki, M; Sawa, T; Takamura, Y; Takashima, M; Yamaoka, R | 1 |
Chhapan, RJ; Ramappa, M; Yerramneni, R | 1 |
Inami, M; Inatani, M; Kamata, K; Kanada, F; Miyake, S; Oki, M; Takamura, Y | 1 |
Al-Hamid, HA; El-Boghdady, NA; Omar, NN; Sadik, NAH | 1 |
Daenzer, JMI; Fridovich-Keil, JL; Rasmussen, SA | 1 |
Feng, M; Feng, W; Hu, Y; Liu, J; Ma, F; Mao, Y; Pan, H; Wang, S; Yang, X; Zhang, D | 1 |
Behulova, D; Bzduch, V; Gerinec, A; Tomcikova, D | 1 |
Huang, W; Li, S; Li, Y; Ma, L; Niu, H; Wei, Z; Xin, G; Xing, Z; Xu, Y; Zeng, Z | 1 |
Cheng, L; Ji, L; Yang, Z | 1 |
Boelen, A; Bosch, AM; Bouva, MJ; de Jonge, R; Heijboer, AC; Schielen, PCJI; Stroek, K; Vaz, FM | 1 |
Chang, CK; Chen, ME; Chen, WA; Chun, MC; How, SC; Li, CT; Lo, CH; Wang, SS; Wu, JW | 1 |
Abdul Rahman, TH; Agarwal, P; Agarwal, R; Ahmad Fisol, NF; Awaludin, NA; Bakar, NS; Iezhitsa, I; Mohamed Ahmed Salama, MS; Mohd Ismail, N; Ozerov, A; Spasov, A | 1 |
Kovtun, S; Varma, SD | 1 |
Balakrishna, N; Giridharan, NV; Pullakhandam, R; Reddy, GB; Reddy, PY; Validandi, V | 1 |
Srinivasan, K; Suresha, BS | 1 |
Hao, LL; Jiang, Y; Wang, RN; Xu, D; Zheng, GY | 1 |
Dai, G; Han, N; Shuai, H; Tan, S; Ye, P; Zhang, M; Zhang, P | 1 |
Abu, EK; Koffuor, GA; Kyei, S; Ramkissoon, P; Sarpong, JF | 1 |
Agarwal, P; Agarwal, R; Alyautdin, R; Iezhitsa, I; Ismail, NM; Krasilnikova, A; Ozerov, A; Rahman, TH; Rozali, KN; Saad, SD; Spasov, A; Zakaria, FK | 1 |
Dai, J; Huang, K; Liu, H; Zhou, J | 1 |
Akiyama, N; Natori, S; Nishigori, H; Sogo, S; Tsujimoto, M; Umeda, IO | 1 |
Adebawo, OO; Adeoye, AO; Ajani, EO; Akinleye, WA; Salako, AA; Salau, BA; Sharlie, PD | 1 |
Huan, Y; Ji, LX; Li, CN; Liu, Q; Shen, N; Shen, ZF | 1 |
Hegde, KR; Kovtun, S; Varma, SD | 1 |
Ghose, S; Gupta, P; Nirmal, J; Velpandian, T; Vijayakumar, AR | 1 |
Hegde, K; Kovtun, S; Varma, SD | 1 |
Jo, K; Kim, CS; Kim, J; Kim, JS; Lee, YM; Sohn, E | 1 |
Das, AM; Illsinger, S; Janzen, N; Lücke, T; Meyer, U; Sander, J; Shin, YS | 1 |
Blessing, K; Kador, PF; Lou, MF; Randazzo, J; Xing, K; Zhang, P | 1 |
Biswas, NR; Gupta, P; Ravi, AK; Sharma, HP; Velpandian, T | 1 |
Gupta, SK; Joshi, S; Mohanty, I; Srivastava, S; Trivedi, D | 1 |
Bakker, HD; Bosch, AM; van Gennip, AH; van Kempen, JV; Wanders, RJ; Wijburg, FA | 1 |
Dmochowska, B; Guo, Z; Madaj, J; Monnier, VM; Nishikawa, Y; Reddy, DV; Rinaldi, PL; Satake, M; Xue, J | 1 |
Krishnaswamy, K; Reddy, GB; Suryanarayana, P | 1 |
Akagi, Y; Kubo, E; Takamura, Y; Tsuzuki, S | 1 |
Gupta, SK; Halder, N; Joshi, S; Srivastava, S; Trivedi, D; Verma, SD | 1 |
PATZ, A | 1 |
MANDEL, P; NORDMANN, J | 1 |
CANNON, E; RITTER, J | 1 |
JOHNSON, J | 1 |
McAULEY, FD | 1 |
HORMANN, E | 1 |
PATTERSON, JW | 3 |
BLACKWELL, J; PIRIE, A; VAN HEYNINGEN, R | 1 |
GOLBERG, L; SCHWARZ, Y | 1 |
ROUHER, F; TRONCHE, P | 2 |
ETIENNE, R; PAUFIQUE, L | 1 |
BORENFREUND, E; DISCHE, Z; ZELMENIS, G | 1 |
DISCHE, Z; YOULUS, J; ZELMENIS, G | 1 |
KADLECOVA, V; LOMICKOVA, H | 1 |
DONNELL, GN; WILSON, WA | 1 |
SEEDORFF, HH | 1 |
HEGGENESS, FW; HILL, JC | 1 |
HANNA, C; O'BRIEN, JE | 1 |
HEGGENESS, FW; HILL, J | 1 |
LERMAN, S | 6 |
BARTALENA, R; TOSELLI, C | 1 |
COTLIER, E | 2 |
FERREIRA, LE | 1 |
KLEITHI, J; MANDEL, P; NORDMANN, J | 1 |
NORDMANN, J | 2 |
BUNTING, KW; PATTERSON, JW; PATTRSON, ME | 1 |
QUARANTA, CA | 1 |
QUARANTA, CA; TEDESCHI, L | 1 |
BERNSTEIN, H; SEGAL, S | 1 |
DIKMAK, E; KINOSHITA, JH; MEROLA, LO | 1 |
KESTON, AS | 1 |
KINOSHITA, JH | 3 |
BURTON, M; FONTAINE, J; LERMAN, S; ZIGMAN, S | 1 |
DISCHE, Z; LARYS, N; ZELMENIS, G | 1 |
BORCHE, LC; CALCAGNO, M; GORDILLODEGELABERT, A; KORC, I; LASALVIA, E | 1 |
KINOSHITA, JH; MEROLA, LO | 1 |
PATTERSON, JW; PATTERSON, ME | 1 |
KINSEY, VE; PATTERSON, JW; PATTERSON, ME; REDDY, DV | 1 |
BUNTING, KW; PATTERSON, JW | 2 |
SEGAL, S; SPATZ, M | 1 |
CANNON, EJ; RITTER, JA | 1 |
HEGGENESS, FW | 1 |
ISHIDA, BK; LERMAN, S | 1 |
MOSS, LK; NEY, LF; SCULLY, TJ; SKAHEN, R | 1 |
Akagi, Y; Kubo, E; Morikubo, S; Takamura, Y; Tsuzuki, S | 1 |
ENNS, JH | 1 |
ANDERSON, WC; FALLS, HF; LOWREY, GH | 1 |
LASKY, MA; REITER, C | 1 |
DAY, PL; STERLING, RE | 1 |
Hegde, KR; Kalakonda, S; Varma, SD | 1 |
Jyothi, M; Sanil, R; Shashidhar, S; Sreekumar, R | 1 |
Albright, CD; Costello, MJ; Freel, CD; Johnsen, S; Marsili, S; Peiffer, RL; Salganik, RI | 1 |
Akagi, Y; Kubo, E; Singh, DP | 1 |
Charlas, J; Colin, J; Thomas, D; Voyer, M | 1 |
Furlan, F; Menni, F; Parini, R; Santer, R; Santus, F; Sersale, G; Vismara, E | 1 |
Danford, A; Ikesugi, K; Kador, PF; Madson, CJ; Mulhern, ML; Shinohara, T | 1 |
Kanth, VR; Kumar, CS; Raju, TN; Ramana, BV; Reddy, GB; Reddy, PU; Suryanarayana, P | 1 |
Betts, D; Blessing, K; Kador, PF; Randazzo, J; Wyman, M | 1 |
Akagi, Y; Kubo, E; Miyazawa, T; Takamura, Y | 1 |
Huang, R; Hughes, CL; Lei, T; Liu, G; Shi, F; Song, Y | 1 |
Babb, T; Blessing, K; Kador, PF; Kompella, UB; Koushik, K; Randazzo, J; Takamura, Y; Zhu, W | 1 |
Kador, PF; Madson, CJ; Mulhern, ML; Randazzo, J; Shinohara, T | 1 |
Liao, GY; Ou, Y; Wu, WT | 1 |
Beneke, G; Schrader, KE | 3 |
Sippel, TO | 3 |
Wilson, WA | 2 |
Patterson, JW; Reszelbach, R | 1 |
Tsui, J; Unakar, NJ | 1 |
Tsui, JY; Unakar, NJ | 2 |
Rathbun, WB | 1 |
Chapman, CJ; Chipault, JR; Mizuno, GR; Pfeiffer, DR | 1 |
Schoon, DV | 1 |
El-Aguizy, HK; Richards, RD; Varma, SD | 1 |
Kador, PF; Kinoshita, JH | 1 |
Gabbay, KH | 1 |
Gona, O | 1 |
Gupta, PP; Mishra, SS; Pandey, DJ; Pandey, DN; Sharma, AL; Srivastava, RK | 1 |
Gupta, PP; Mishra, SS; Pandey, DJ; Sharma, AL; Srivastava, RK | 1 |
Albal, MV; Bulakh, PM; Chandorkar, AG | 1 |
Hirota, K; Ikeda, M; Ohmori, S; Tsuboi, S; Uda, N | 1 |
Gupta, K; Mathur, RL | 1 |
Giblin, F; Harding, C; Kinoshita, JH; Kodama, T; Reddy, VN | 1 |
Hiraiwa, N; Ishiguro, I | 1 |
Macdonald, I; Williams, CA | 1 |
Datiles, M; Fukui, H; Kinoshita, JH; Kuwabara, T | 1 |
Simoons, FJ | 1 |
Varma, SD | 1 |
Beyer-Mears, A; Cruz, E; Nicolas-Alexandre, J; Varagiannis, E | 1 |
Brescia, M; Cotlier, E; Niven, T; Sharma, YR | 1 |
Claringbold, LJ; Jay, BS; Jones, RB; Kissun, RD; Menzies, IS; Mount, JN; Rice, NS; Winder, AF | 1 |
Carper, DA; Kinoshita, JH; Piatigorsky, J; Shinohara, T | 1 |
Glonek, T; Greiner, JV; Kopp, SJ; Sanders, DR | 1 |
Price, G; Tsui, J; Unakar, NJ | 1 |
Fells, P; Jones, RB; Kissun, RD; Menzies, IS; Mount, JN; Winder, AF | 1 |
Fu, SC; Gona, O | 1 |
Bunn, HF; Chiou, SH; Chylack, LT; Kinoshita, JH | 1 |
Beyer-Mears, A; Farnsworth, PN | 1 |
Abraham, EC; Cherian, M; Johnson, M; Tsui, J; Unakar, NJ | 1 |
Glover, JP; Jacot, JL; Laver, NM; Robison, WG | 1 |
Chung, SK; Chung, SS; Lee, AY | 1 |
Blumberg, J; Dallal, G; Martin, A; Meydani, M; Sastre, J; Smith, D; Taylor, A | 1 |
Azuma, M; Inoue, E; Oka, T; Shearer, TR | 1 |
Dai, SF; Qi, SW; Zhang, LZ | 1 |
Calvin, HI; Fu, SC; Hua, JC; Pan, S | 1 |
Engerman, RL; Kern, TS | 2 |
Kador, PF; Sato, S; Takahashi, Y; Wyman, M | 2 |
Ferris, F; Kador, PF; Takahashi, Y; Wyman, M | 1 |
Anthony, P; Johnson, M; Tsui, J; Unakar, NJ | 1 |
Bekhor, I; Kannan, R; Mackic, JB; McComb, JG; Ross-Cisneros, FN; Weiss, MH; Zlokovic, BV | 1 |
Giblin, FJ; Reddy, VN; Sasaki, H; Yokoyama, T | 1 |
Ren, X; Zhao, H | 1 |
Bagchi, M; Bobrowski, WF; Harding, CV; Tsui, JY; Unakar, NJ | 1 |
Augustin, W; Kador, PF; Takahashi, Y; Wyman, M | 1 |
Okamura, R; Taura, T; Teshima, R | 3 |
Mori, K | 1 |
Clark, JI; Livesey, JC; Steele, JE | 2 |
Akagi, Y; Ikebe, H; Okamoto, S; Tanimoto, T; Terubayashi, H; Tsuji, T | 1 |
Cunnick, J; Gonzalez, K; Takemoto, DJ; Udovichenko, I | 1 |
Akagi, Y; Ikebe, H; Okamoto, S; Terubayashi, H; Tsuji, T | 1 |
Abitbol, G; Birlouez-Aragon, I; Cathelineau, G; Ravelontseheno, L; Villate-Cathelineau, B | 1 |
Akagi, Y; Kobayashi, T; Kubo, E; Mori, K; Takahashi, Y; Takayanagi, K; Tsuzuki, S | 1 |
Du, GH; Qiu, Y; Tian, YE; Zhang, JT | 1 |
Balaban, RS; Ceckler, TL; Kador, PF; Lizak, MJ; Mori, K | 2 |
Basso, MD; Blouin, P; Glover, JP; Hohman, TC; Jacot, JL; Laver, NM; Robinson, WG | 1 |
Bekhor, I; Li, GW; Wen, Y | 1 |
Lou, MF; Xu, GT; York, B; Zigler, S | 1 |
Bond, J; Donaldson, P; Green, C; Kistler, J | 1 |
Bai, C; Dai, S; Deng, X; Ni, T; Qi, S; Zhang, L | 1 |
Feigenbaum, A; Laframboise, R; Pitkänen, S; Robinson, BH | 1 |
Huang, FY; Hur, Y; Lee, SM; Tzou, DL; Yeung, HN | 1 |
Monnier, VM; Saxena, AK; Saxena, P | 1 |
Kador, PF; Lackner, PA; Lizak, MJ; Rodriguez, L; Sato, S; Wyman, M | 1 |
Johnson, M; Tsui, J; Unakar, NJ | 1 |
Amin, R; Frank, RN; Hohman, TC; Kennedy, A | 1 |
Kador, PF; Neuenschwander, H; Takahashi, Y | 1 |
Ishiguro, I; Majima, Y; Niwa, T; Ohta, Y; Torii, H; Yamasaki, T | 1 |
Kador, PF; Mori, K; Sato, S; Wyman, M | 1 |
Glover, JP; Hosotani, H; Jacot, JL; Lois, N; Robison, WG | 1 |
Punitham, R; Ramakrishnan, S; Sulochana, KN | 1 |
Hightower, KR; Misiak, P | 1 |
Blum, PS; Jernigan, HM; Liu, Y; Merola, LO; Stimbert, CD; Zigler, JS | 1 |
Unakar, NJ | 1 |
Blum, PS; Ekambaram, MC; Jernigan, HM; Liu, Y; Stimbert, CD | 1 |
Blessing, K; Greentree, W; Inoue, J; Kador, PF; Lackner, PA; Lizak, MJ; Mori, K; Rodriguez, L; Sato, S; Secchi, EF | 1 |
Kasai, K; Kikuchi, M; Koga, T; Matsudo, T; Mori, K; Saito, M; Sasaki, T; Yamakoshi, J | 1 |
Horikoshi, H; Inoue, T; Yokoyama, T; Yoshida, Y | 1 |
Akagi, Y; Fukuda, M; Kubo, E; Miyoshi, N | 1 |
Ali, AH; Devamanoharan, PS; Henein, M; Rutzen, AR; Varma, SD | 1 |
Ishiguro, I; Majima, Y; Niwa, T; Ohta, Y; Yamasaki, T | 1 |
Goto, H; Ishiguro, I; Majima, Y; Niwa, T; Ohta, Y; Yamasaki, T | 1 |
Banditelli, S; Boldrini, E; Cappiello, M; Cecconi, I; Dal Monte, M; Del Corso, A; Marini, I; Mura, U; Vilardo, PG | 1 |
Ali, AH; Devamanoharan, PS; Henein, M; Varma, SD | 1 |
Igarashi, H; Sakagami, K; Tanaka, K; Yoshida, A | 1 |
Chuang, SA; Ho, Y; Huang, FY; Shaw, TS | 1 |
Ai, Y; Bernard, DJ; Huang, K; Ning, C; O'Brien-Jenkins, A; Reynolds, R; Segal, S; Stambolian, D; Wynshaw-Boris, T; Zheng, Z | 1 |
Majima, Y; Niwa, T; Ohta, Y; Yamasaki, T | 1 |
Asada, M; Cao, Q; Choeh, K; Fujimoto, A; Hsiao, KJ; Imamura, T; Murayama, K; Niihira, S; Ohtake, A; Okano, Y; Reichardt, JK; Yamano, T; Yang, Y | 1 |
Gusek-Schneider, GC; Jünemann, AG; Naumann, GO; Shin, YS; Viestenz, A | 1 |
Alam, S; Kador, PF; Murata, M; Ohta, N; Sakurai, S; Sato, S; Tsai, J | 1 |
Dong, D; Hou, W; Jia, W; Liu, Y; Lu, A | 1 |
He, S; Li, N; Wang, F | 1 |
Akagi, Y; Kubo, E; Sato, M; Takamura, Y; Tsuzuki, S; Yagi, H | 1 |
Fukushi, S; Kador, P; Kinoshita, JH; Merola, LO | 1 |
Aldinger, CE; MacDonald, DP; Peterson, MJ; Sarges, R | 1 |
Kaloud, H; Prestele, H; Schenker, H; Sitzmann, FC | 1 |
Schwarz, V | 1 |
Malone, J; Mellman, WJ; Mennuti, MT; Needelman, B; Nichols, CW; Rawnsley, BE; Tedesco, TA | 1 |
Crollini, C; Gupta, JD; Harley, JD; Mutton, P; Stephens, T | 1 |
Lambotte, C | 1 |
Colin, J; Satge, P; Schapira, F; Thomas, D; Voyer, M | 1 |
Kador, PF; Kinoshita, JH; Zigler, JS | 1 |
Genyea, C; Reddan, JR; Reddy, VN; Unakar, NJ | 1 |
Hightower, KR; Kinsey, VE | 1 |
Beyer-Mears, A; Burke, P; Farnsworth, PN; Fu, SC | 1 |
Beyer-Mears, A; Farnsworth, PN; Fu, SC; Yeh, CK | 1 |
van Heyningen, R | 2 |
Fu, SC; Hart, R; Lewis, KE; Ocken, PR; Wagner, BJ; White, JH | 1 |
Horning, EC; Pfaffenberger, CD; Szafranek, J | 1 |
Chakrapani, B; Lim, CP; Reddy, VN; Schwass, D | 1 |
Fournier, DJ; Patterson, JW; Schenck, D | 1 |
Eckert, H; Koch, HR; Wendt, H | 1 |
Imai, Y | 1 |
Stephens, T | 1 |
Fukui, HN; Kinoshita, JH; Kuwabara, T; Sakuragawa, M | 1 |
Winder, AF | 1 |
Johnson, MJ; Unakar, NJ | 1 |
Hasegawa, E; Hatase, O; Itano, T; Koshimoto, HN; Matsui, H; Tokuda, M | 1 |
Bekhor, I; Shi, S; Tsui, J; Unakar, NJ; Wen, Y | 1 |
Johnson, MJ; Tsui, JY; Unakar, NJ | 2 |
Ren, XH; Zhao, HR | 1 |
Bekhor, I; Shu, S; Unakar, NJ; Wen, Y | 1 |
Chang, C; Cheng, HM; Garrido, L; Kuan, WP; Xiong, J | 1 |
Itoi, M; Kasuya, M; Kobayashi, S; Sunaga, H; Suzuki, KT | 1 |
Akagi, Y | 1 |
Kaizuka, Y | 1 |
Akagi, Y; Ikebe, H; Matsumoto, Y; Mori, K; Tanimoto, T; Terubayashi, H; Tsutsumi, M | 1 |
Igarashi, H; Tanaka, K; Yoshida, A | 2 |
Akagi, Y; Ikebe, H; Okamoto, S; Terubayashi, H; Tsutsumi, M | 1 |
Beyer-Mears, A; Cruz, E; Diecke, FP; Mistry, K | 1 |
Devamanoharan, PS; Henein, M; Ramachandran, S; Varma, SD | 1 |
Bekhor, I; Shi, ST; Unakar, NJ; Wen, Y | 1 |
Dang, L; Johnson, M; Tsui, JY; Unakar, NJ | 1 |
Murthy, MS | 1 |
Hoenders, HJ; van Boekel, MA | 1 |
Couet, C; Debry, G; Jan, P | 1 |
Gupta, SK; Joshi, S | 2 |
Bekhor, I; Unakar, NJ; Wen, Y | 1 |
Balestrieri, P; Cotticelli, L; Frunzio, S; Giovane, A; Rinaldi, E; Rinaldi, M; Simonelli, F | 1 |
Koyama-Ito, H | 1 |
Bekhor, I; Shi, ST; Unakar, NJ | 1 |
Akagi, Y; Ikebe, H; Matsumoto, Y; Mori, K; Tanimoto, T; Terubayashi, H; Tsuji, T | 1 |
Brockstedt, M; Douwes, AC; Endres, W; Jakobs, C; Shin, YS; Stellaard, F | 1 |
Kato, K; Miwa, I; Mizota, M; Murakami, K; Murakami, N; Nakayama, K; Ohta, M; Okuda, J | 1 |
Alcala, J; Katar, M; Tsui, J; Unakar, N | 1 |
Cheng, HM; Tsubota, K; Xiong, H; Xiong, J | 1 |
Azuma, M; David, LL; Matsumoto, T; Murachi, T; Shearer, TR | 1 |
Armstrong, GR; Bascal, ZA; Wolff, SP; Woollard, AC | 1 |
Harding, JJ; Roberts, KA | 1 |
Ansari, NH; Srivastava, SK | 2 |
Houlder, N; Kinoshita, JH; Robison, WG | 1 |
Fu, SC; Huang, WQ; Zhang, JP | 1 |
Hattori, H; Kaneda, M; Majima, Y; Torii, H | 1 |
Furukawa, F; Hasegawa, R; Hayashi, Y; Jang, JJ; Sato, H; Takahashi, M; Toyoda, K | 1 |
Bekhor, I; Carper, D; Nishimura, C; Shi, S; Unakar, NJ | 1 |
Bagchi, M; Bobrowski, WF; Chylack, LT; Dang, L; Harding, CV; Harding, D; Jampel, RS; Tsui, JY; Unakar, NJ | 1 |
Alloussi, S; Birlouez-Aragon, I; Fevrier, C; Morawiec, M | 1 |
Auricchio, G; De Rosa, G; Di Meo, A; Lauro, G; Napoli, R; Nesti, A; Picardi, A; Rinaldi, E; Simonelli, F | 1 |
Akagi, Y; Ikebe, H; Matumoto, Y; Terubayashi, H; Tsuji, T | 1 |
Cheng, HM; Xiong, H | 1 |
Ansari, NH; Datiles, MB; Maumenee, AE; Srivastava, SK; Stark, WJ; Stevens, RE | 1 |
Johnson, M; Tsui, J; Unakar, N | 1 |
Clark, JI; Giblin, FJ; Ikebe, H; Livesey, JC; Reddy, VN | 1 |
Beyer-Mears, A; Bucci, FA; Cruz, E; Del Val, M | 1 |
Ahn, CB; Anderson, JA; Cho, ZH; Garner, WH; Juh, SC; Kim, I | 1 |
Cai, MZ; Kuck, JF; Yu, NT | 1 |
Igarashi, H; Kusakabe, M; Tanaka, K; Yoshida, A | 1 |
Clark, JI; Osgood, TB; Trask, SJ | 1 |
Cheng, HM; Kawaba, T; Kinoshita, JH | 1 |
Dong, DS; Fu, SC; Keeting, PE; Lysz, TW | 1 |
Merola, LO; Ng, MC; Tsui, JY; Unakar, NJ | 1 |
Akagi, Y; Dvornik, D; Gonzalez, R; Kador, PF; Kinoshita, JH; Robison, WG | 1 |
Iwata, S; Kamiya, M; Majima, Y | 2 |
Williams, CA | 1 |
He, SZ | 1 |
Huang, XR | 1 |
Chen, TH; Desposito, F; Kuerer, HM; Shih, LY | 1 |
Reddy, VN; Taura, T | 1 |
Fukushima, T; Imaizumi, K; Minato, Y; Okaniwa, A; Takeshita, M; Wada, I | 1 |
Akagi, Y; Kador, PF; Kinoshita, JH; Terubayashi, H | 1 |
Bekhor, I; Hsu, MY; Jaskoll, TF; Unakar, NJ | 1 |
Bekhor, I | 1 |
Akagi, Y; Itoi, M; Miyamoto, Y; Nakamoto, S; Terubayashi, H; Tutumi, M; Yokoi, N | 1 |
Akagi, Y; Chamoto, K; Ibaraki, N; Itoi, M; Miyamoto, Y; Okamoto, S; Tasaka, H; Terubayashi, H; Tsutsumi, M; Yokoi, N | 1 |
Harding, JJ; Lewis, BS | 1 |
Alcala, J; Katar, M; Tsui, JY; Unakar, NJ | 1 |
Cream, JJ; Mount, JN; Muhlemann, MF | 1 |
Gona, O; White, JH | 1 |
Adrian, J; Kechrid, RM; Poiffait, A | 1 |
Burns, MS; File, DM | 1 |
Harries, W; Tsui, J; Unakar, NJ | 2 |
Auricchio, G; Della Corte, M; Iuliano, G; Latte, F; Libondi, T; Menzione, M | 1 |
Kador, PF; Kinoshita, JH; Sharpless, NE | 1 |
Beyer-Mears, A; Cruz, E; Varagiannis, E | 1 |
Beyer-Mears, A; Cruz, E; Kelly, K | 1 |
Akagi, Y; Itoi, M; Kador, PF; Kinoshita, JH; Nakaji, Y; Tasaka, H | 1 |
Eagle, RC; Harris, H; Hodes, B; Scarpino-Myers, V; Stambolian, D | 1 |
Creighton, MO; Ross, WM; Sanwal, M; Stewart-DeHaan, PJ; Trevithick, JR | 1 |
Dvornik, D; Gonzalez, R; Greselin, E; Simard-Duquesne, N | 1 |
Fielder, AR; Menzies, JS; Mount, JN; Winder, AF | 1 |
Ratnakar, KS | 1 |
Chaplain, TL; Meakem, T; Williams, EH | 1 |
Giblin, FJ; Reddy, VN; Taura, T | 1 |
Benson, PF; Blunt, S; Brown, SP | 1 |
Gupta, JD; Harley, JD; Irvine, S; Mutton, P | 1 |
Harper, PS | 1 |
Gitzelmann, R | 2 |
Arnaud, A; Bastide, P; Dastugue, G; Tronche, P | 1 |
Fournier, DJ; Patterson, JW | 2 |
Dvornik, E; Gabbay, KH; Kinoshita, JH; Krami, M; Merola, LO; Sestanj, K; Simard-Duquesne, N; Varma, SD | 1 |
Broekhuyse, RM | 1 |
Sidbury, JB | 1 |
Donnell, GN; Frasier, SD; McVie, R; Ng, WG; Olambiwonnu, NO | 1 |
Desjardins, L; Kelly, S; Leikhim, E | 1 |
Kaloud, H; Mayer, R; Paltauf, F; Sitzmann, FC | 1 |
Gopalan, C; Seetharam Bhat, K | 1 |
Bert, M; Hilliard, R; Monteleone, JA; Monteleone, PL | 1 |
Kinoshita, JH; Varma, SD | 1 |
Heffley, JD; Williams, RJ | 1 |
Bergeder, HD; Fink, H; Hockwin, O; Ninnemann, U | 1 |
Sychlowy, A | 1 |
Pau, H | 1 |
Gupta, JD; Harley, JD; Irvine, S | 1 |
Bergren, WR; Donnell, GN; Frasier, SD; Oberman, AE; Wilson, WA | 1 |
Dvornik, D; Simard-Duquesne, N | 1 |
Drevich, VF; Salganik, RI; Solov'eva, NA | 1 |
Beutler, E; Degnan, M; Krill, A; Kuhl, W; Levy, N; Matsumoto, F; Sparkes, R | 1 |
Cogan, DG | 1 |
Harris, RC | 1 |
Kinoshita, JH; Merola, LO; Obazawa, H | 1 |
Spector, A | 1 |
Brückner, R; Hess, R; Keberle, H; Pericin, C; Tripod, J | 1 |
Beutler, E | 1 |
Howell, RR; Pickering, WR | 1 |
Beutler, E; Srivastava, SK | 2 |
Keiding, S; Mellemgaard, L | 1 |
Cook, JG; Don, NA; Mann, TP | 1 |
Byrnes, RJ; Ortwerth, BJ | 1 |
Hockwin, O | 2 |
Csordás, J; Méhes, K; Ritecz, E; Rubecz, I | 1 |
Kuttner, RE; Portoghese, AJ | 1 |
Beneke, G; Mähr, G; Rommel, K; Schrader, KE | 1 |
Ito, H; Tamura, S; Tsutsumi, S | 1 |
Nakai, K; Tamura, S | 1 |
Tamura, S; Tsuzuki, S | 1 |
Barber, GW; Kinoshita, JH; Merola, LO; Tung, B | 1 |
Berger, R; Broyer, M | 1 |
Bergeder, HD | 1 |
Cremer-Bartels, G; Ganter, K; Hockwin, O; Werry, H | 1 |
Philipson, B | 3 |
Burns, RP; Fraunfelder, FT; Hofeldt, A; Weimar, V | 1 |
Feldman, GL; Windeler, AS | 1 |
Duke, JR; Richter, CP | 2 |
Gerhard, JP; Klethi, J; Nordmann, J | 1 |
Andrews, JS; Hatcher, H | 1 |
De Mate, HC; De Sirtori, OA; Korc, I; Muse, MI | 1 |
Linneweh, F; Schaumlöffel, E; Vetrella, M | 1 |
Hager-Malecka, B; Sychlowy, A; Szczepański, Z | 1 |
Beutler, E; Casey, EC; Monteleone, JA; Monteleone, PL; Utz, CL | 1 |
Cramer, K; Rommel, K | 1 |
Beaty, C; Cotlier, E | 1 |
Kinoshita, JH; Merola, LO; Tung, B | 1 |
Bettman, JW; Fung, WE; Noyes, PP; Vincent, NJ; Webster, RG | 1 |
Sulcová, H | 1 |
Grimes, P; von Sallmann, L | 1 |
Bergeder, HD; Hockwin, O; Kaiser, L | 1 |
Claudio, C; Gino, G | 1 |
Sinha, BN | 1 |
Green, M; Weller, CA | 1 |
Cogan, DG; Kinoshita, JH; Kuwabara, T | 1 |
Ionăşescu, V; Luca, N | 1 |
Becker, B; Cotlier, E | 2 |
Rowe, KW; Wittgenstein, E | 1 |
Hagiwara, S; Kita, S; Nagasawa, T; Nakai, K; Tamura, S | 1 |
Blair, A; Roth, H; Segal, S | 1 |
VAN HAYNINGEN, R | 1 |
Chamaraj, D; Gopalakrishna, K; Pattabiraman, TN | 1 |
Gopalakrishna, K; Nayak, BR; Pattabiraman, TN; Rao, PN | 1 |
Funahashi, M; Hayano, S; Ono, H | 1 |
Obrosova, IG; Stevens, MJ | 1 |
Hollows, FC; Hutton, JC; Regtop, HL; Schofield, PH; Williams, JF | 1 |
Gopalakrishna, K; Pattabiraman, TN | 1 |
Friedburg, D; Mayer, U | 1 |
24 review(s) available for galactose and Cataract
Article | Year |
---|---|
Diagnosing the oil drop: A case report and review of the literature.
Topics: Cataract; Cataract Extraction; Child, Preschool; Crystallins; Electrophoresis; Galactose; Galactosemias; Humans; Lens Implantation, Intraocular; Male | 2019 |
Recommendations for newborn screening for galactokinase deficiency: A systematic review and evaluation of Dutch newborn screening data.
Topics: Cataract; Galactose; Galactosemias; Humans; Infant, Newborn; Neonatal Screening; Netherlands; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Retrospective Studies | 2018 |
Clinical features of galactokinase deficiency: a review of the literature.
Topics: Carbohydrate Metabolism, Inborn Errors; Cataract; Galactokinase; Galactose; Galactosemias; Humans; Pseudotumor Cerebri | 2002 |
SELECTED TOPICS IN OPHTHALMIC BIOCHEMISTRY.
Topics: Biochemical Phenomena; Biochemistry; Cataract; Eye; Eye Proteins; Galactose; Humans; Ion Exchange; Lens, Crystalline; Ophthalmology; Peptide Hydrolases; Retinal Pigments; Vitamin A | 1963 |
METABOLIC PATHWAYS IN EXPERIMENTAL SUGAR AND RADIATION CATARACT.
Topics: Carbohydrate Metabolism; Cataract; Diabetes Mellitus; Galactose; Metabolic Networks and Pathways; Pathology; Radiation Injuries; Radiation Injuries, Experimental; Research; Xylose | 1965 |
[Galactokinase deficiency].
Topics: Cataract; Female; Galactokinase; Galactose; Galactosemias; Gene Frequency; Heterozygote; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; Intracranial Hypertension; Male; Pedigree; Prognosis; Rare Diseases; Risk Factors; Sex Distribution | 1976 |
The nutritional origin of cataracts.
Topics: Adult; Animals; Blood Glucose; Breath Tests; Cataract; Cattle; Dehydration; Diarrhea; Female; Galactose; Heat Exhaustion; Humans; Hydrolysis; Lactose; Male; Middle Aged; Milk; Prospective Studies | 1984 |
Diabetic and galactosaemic cataracts.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Galactose; Galactosemias; Glucose; Humans; Imidazoles; Imidazolidines; Intracellular Fluid; Lens, Crystalline; Mice; Osmosis; Rats; Sugar Alcohols | 1984 |
[The biochemical basis of the complications of diabetes].
Topics: Aldehyde Reductase; Cataract; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Fructose; Galactose; Glucose; Glycated Hemoglobin; Humans; Kidney; L-Iditol 2-Dehydrogenase; Proteins; Sorbitol; Tissue Distribution | 1984 |
Metabolic effects of dietary galactose.
Topics: Adult; Animals; Blood Glucose; Cataract; Dietary Carbohydrates; Female; Galactose; Galactosemias; Humans; Infant, Newborn; Insulin; Lactose; Lactose Intolerance; Male; Rats | 1982 |
Ocular lens and galactose cataracts.
Topics: Cataract; Galactose; Humans; Lens, Crystalline; Microscopy, Electron, Scanning | 1998 |
Aldose reductase in diabetic complications of the eye.
Topics: Aldehyde Reductase; Animals; Cataract; Cattle; Chromans; Cornea; Diabetes Complications; Diabetic Retinopathy; Epithelium; Eye Diseases; Female; Galactitol; Galactose; Humans; Imidazoles; Imidazolidines; Lens, Crystalline; Mice; Mice, Obese; NADP; Polymers; Pregnancy; Rats; Regeneration; Retina; Rodentia; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases; Xylitol | 1979 |
Galactosaemia and the problem of galactose toxicity.
Topics: Animals; Cataract; Female; Galactose; Galactosemias; Genes; Heterozygote; Hexosephosphates; Homozygote; Humans; Nucleotidyltransferases; Phosphotransferases; Pregnancy; UTP-Hexose-1-Phosphate Uridylyltransferase | 1975 |
Riboflavin deficiency, galactose metabolism and cataract.
Topics: Animals; Cataract; Erythrocytes; Galactose; Glutathione Reductase; Humans; Phosphotransferases; Rats; Riboflavin; Riboflavin Deficiency | 1976 |
Sugar alcohols in the pathogenesis of galactose and diabetic cataracts.
Topics: Aldehyde Reductase; Animals; Carbohydrate Metabolism, Inborn Errors; Cataract; Chemical Phenomena; Chemistry; Diabetes Complications; Galactose; Galactosemias; Humans; Lens, Crystalline; Sorbitol; Sugar Alcohols | 1976 |
Lactose and cataract in humans: a review.
Topics: Animals; beta-Galactosidase; Cataract; Dietary Carbohydrates; Galactokinase; Galactose; Humans; Lactase; Lactose; Milk; UTP-Hexose-1-Phosphate Uridylyltransferase | 1991 |
Effect of radioprotective agents on X-ray cataracts.
Topics: Amifostine; Animals; Cataract; Cysteine; Galactose; Lens, Crystalline; Radiation Injuries, Experimental; Radiation-Protective Agents | 1989 |
Metabolism of lactose and galactose in man.
Topics: Adult; Age Factors; beta-Galactosidase; Blood Glucose; Body Composition; Calcium; Cataract; Child; Cholesterol; Dietary Carbohydrates; Digestion; Ethanol; Female; Galactose; Gastric Emptying; Glucose; Glycogen; Humans; Infant; Infant, Newborn; Insulin; Intestinal Absorption; Lactose; Lactose Intolerance; Liver; Male; Respiration; Sex Factors; Triglycerides | 1986 |
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution | 1985 |
Mechanisms initiating cataract formation. Proctor Lecture.
Topics: Acetates; Adenosine Triphosphatases; Aged; Alcohol Oxidoreductases; Animals; Biological Transport; Cataract; Cations, Divalent; Cattle; Diabetes Complications; Dimethyl Sulfoxide; Female; Galactose; Glutarates; Humans; Isoquinolines; Lens, Crystalline; Male; Mice; Middle Aged; Osmosis; Ouabain; Potassium; Sodium; Sorbitol; Toluidines; Water-Electrolyte Balance; Xylose | 1974 |
[Galactosemia: a hereditary galactose intolerance].
Topics: Age Factors; Cataract; Deficiency Diseases; Erythrocytes; Galactose; Galactosemias; Galactosidases; Genotype; Humans; Lactose; Nucleotidyltransferases; Phosphotransferases | 1972 |
The pathogenesis of subcapsular opacities of the lens (permeability-cataract).
Topics: Animals; Carbohydrate Metabolism; Cataract; Cations, Divalent; Colloids; Epithelium; Galactose; Humans; Lens, Crystalline; Metabolic Diseases; Organ Size; Osmotic Pressure; Permeability; Postural Balance; Potassium; Proteins; Sodium; Urethane; Water | 1974 |
Physiological chemistry of the eye.
Topics: Amino Acids; Animals; Biological Transport, Active; Cataract; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Cholinesterase Inhibitors; Chondroitin; Collagen; Cornea; Crystallins; Epithelium; Galactose; Galactosemias; Glucose; Humans; Lens, Crystalline; Naphthoquinones; Ocular Physiological Phenomena; Protein Biosynthesis; Rabbits; Sulfhydryl Compounds; Wound Healing | 1969 |
Galactose cataract: a review.
Topics: Age Factors; Alcohol Oxidoreductases; Aminoisobutyric Acids; Animals; Cataract; Dairy Products; Galactose; Galactosemias; Glucose; Humans; Inositol; Lens, Crystalline; Milk; Milk, Human; Osmosis; Phospholipids; Rabbits; Rats; Sorbitol; Sugar Alcohols; Xylose | 1971 |
1 trial(s) available for galactose and Cataract
Article | Year |
---|---|
Effects of topical administration of an aldose reductase inhibitor on cataract formation in dogs fed a diet high in galactose.
Topics: Administration, Topical; Aldehyde Reductase; Animal Feed; Animals; Cataract; Diet; Dogs; Enzyme Inhibitors; Galactose; Male | 2006 |
411 other study(ies) available for galactose and Cataract
Article | Year |
---|---|
β-Galactosidase therapy can mitigate blood galactose elevation after an oral lactose load in galactose mutarotase deficiency.
Topics: beta-Galactosidase; Carbohydrate Epimerases; Cataract; Galactitol; Galactose; Galactosemias; Humans; Lactose | 2022 |
Association of Age-Related Cataract Risk with High Polygenetic Risk Scores Involved in Galactose-Related Metabolism and Dietary Interactions.
Topics: Adult; Cataract; Diet; Galactose; Humans; Lactose; Polymorphism, Single Nucleotide; Risk Factors | 2022 |
Neonatal GALT gene replacement offers metabolic and phenotypic correction through early adulthood in a rat model of classic galactosemia.
Topics: Adult; Animals; Cataract; Galactose; Galactosemias; Humans; Infant, Newborn; Liver; Neonatal Screening; Rats; UTP-Hexose-1-Phosphate Uridylyltransferase | 2022 |
Atm inhibition decreases lens opacity in a rat model of galactose-induced cataract.
Topics: Actins; Animals; Ataxia Telangiectasia Mutated Proteins; Blindness; Cataract; Galactose; Lens, Crystalline; Rats; RNA, Messenger | 2022 |
Histone acetyltransferase inhibition reverses opacity in rat galactose-induced cataract.
Topics: Animals; Cataract; Galactose; Histone Acetyltransferases; Histones; Lens, Crystalline; Rats | 2022 |
Histone acetyltransferase and Polo-like kinase 3 inhibitors prevent rat galactose-induced cataract.
Topics: Animals; Cataract; Cell Cycle Proteins; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Galactose; Histone Acetyltransferases; Lens, Crystalline; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley | 2019 |
Esculetin and idebenone ameliorate galactose-induced cataract in a rat model.
Topics: Animals; Cataract; Galactose; Glutathione; Rats; Rats, Sprague-Dawley; Ubiquinone; Umbelliferones | 2020 |
A pilot study of neonatal GALT gene replacement using AAV9 dramatically lowers galactose metabolites in blood, liver, and brain and minimizes cataracts in GALT-null rat pups.
Topics: Animals; Animals, Newborn; Brain; Cataract; Dependovirus; Disease Models, Animal; Galactose; Galactosemias; Genetic Therapy; Liver; Pilot Projects; Rats; UTP-Hexose-1-Phosphate Uridylyltransferase | 2021 |
Alginate Oligosaccharide Prevents against D-galactose-mediated Cataract in C57BL/6J Mice via Regulating Oxidative Stress and Antioxidant System.
Topics: Alginates; Animals; Antioxidants; Blotting, Western; Catalase; Cataract; Galactose; Heme Oxygenase-1; Lens, Crystalline; Male; Malondialdehyde; Membrane Proteins; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; NF-E2-Related Factor 2; Oligosaccharides; Oxidative Stress; Real-Time Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tumor Suppressor Protein p53 | 2021 |
Cataract and early nystagmus due to galactokinase deficiency.
Topics: Cataract; Diagnostic Techniques, Ophthalmological; Galactose; Galactosemias; Humans; Infant; Male; Mutation; Nystagmus, Pathologic | 2017 |
d-galactose induces premature senescence of lens epithelial cells by disturbing autophagy flux and mitochondrial functions.
Topics: Adenosine Triphosphate; Antioxidants; Autophagy; Calcium Signaling; Cataract; Cell Line; Cell Proliferation; Cellular Senescence; Eye Proteins; Galactose; Gene Expression Regulation; Humans; Hypoglycemic Agents; Lens, Crystalline; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Oxidative Stress; Reactive Oxygen Species | 2018 |
Upregulations of Clcn3 and P-Gp Provoked by Lens Osmotic Expansion in Rat Galactosemic Cataract.
Topics: Aldehyde Reductase; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cataract; Cells, Cultured; Chloride Channels; Diabetes Complications; Dogs; Galactose; Lens, Crystalline; Male; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Up-Regulation | 2017 |
Effects of glycation on human γd-crystallin proteins by different glycation-inducing agents.
Topics: Cataract; Diabetes Complications; Fructosamine; Galactose; gamma-Crystallins; Glycation End Products, Advanced; Glycosylation; Humans; Lens, Crystalline; Lysine; Protein Aggregation, Pathological; Protein Denaturation; Pyruvaldehyde; Ribose | 2018 |
Effects of magnesium taurate on the onset and progression of galactose-induced experimental cataract: in vivo and in vitro evaluation.
Topics: Administration, Oral; Administration, Topical; Animals; Calcium; Catalase; Cataract; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Galactose; Glutathione; Lens, Crystalline; Magnesium; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Taurine | 2013 |
Protective effect of caffeine against high sugar-induced transcription of microRNAs and consequent gene silencing: a study using lenses of galactosemic mice.
Topics: Animals; Caffeine; Cataract; Disease Models, Animal; Galactose; Galactosemias; Gene Silencing; Humans; Lens, Crystalline; Mice; Mice, Inbred Strains; MicroRNAs; Oxidative Stress; Transcription, Genetic | 2013 |
Increased risk of cataract development in WNIN-obese rats due to accumulation of intralenticular sorbitol.
Topics: Animals; Cataract; Crystallins; Diabetes Mellitus, Experimental; Galactose; Glucose; Hot Temperature; Lens, Crystalline; Obesity; Rats; Risk Factors; Sorbitol; Ultraviolet Rays | 2013 |
Antioxidant potential of fungal metabolite nigerloxin during eye lens abnormalities in galactose-fed rats.
Topics: Aldehyde Reductase; Animals; Antioxidants; Aspergillus niger; Benzoates; Cataract; Diabetes Mellitus, Experimental; Galactose; Glutathione; Lens, Crystalline; Lipid Peroxidation; Male; Oxidative Stress; Polymers; Propane; Rats; Rats, Wistar; Sulfhydryl Compounds; Tryptophan | 2013 |
[Evaluation of calcium dobesilate for its anti-cataract potential in experimental rat models].
Topics: Animals; Calcium Dobesilate; Cataract; Galactose; Rats; Rats, Wistar | 2013 |
The Chemopreventive Peptide Lunasin Inhibits d-Galactose- Induced Experimental Cataract in Rats.
Topics: Animals; Apoptosis; Cataract; Cell Line; Female; Galactose; Humans; Lens, Crystalline; Lipid Peroxidation; Male; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Soybean Proteins | 2016 |
Anti-Cataract Potential of Heliotropium indicum Linn on Galactose-Induced Cataract in Sprague-Dawley Rats.
Topics: Animals; Cataract; Disease Models, Animal; Eye Proteins; Female; Galactose; Heliotropium; Lens, Crystalline; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley | 2017 |
Mechanism of the anticataract effect of liposomal MgT in galactose-fed rats.
Topics: Animals; Calcium; Calpain; Cataract; Disease Progression; Galactose; Homeostasis; Lens, Crystalline; Liposomes; Magnesium; Nitrosation; Oxidative Stress; Particle Size; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Taurine | 2016 |
Selenite and ebselen supplementation attenuates D-galactose-induced oxidative stress and increases expression of SELR and SEP15 in rat lens.
Topics: Aldehyde Reductase; Animals; Antioxidants; Azoles; beta-Crystallins; Blotting, Western; Catalase; Cataract; Dietary Supplements; Epithelial Cells; Galactose; Glutathione Peroxidase; Heat-Shock Proteins; Isoindoles; Lens, Crystalline; Male; Methionine Sulfoxide Reductases; Microscopy, Electron, Transmission; Organoselenium Compounds; Oxidative Stress; Rats, Sprague-Dawley; Selenious Acid; Selenoproteins; Superoxide Dismutase-1; Trace Elements | 2016 |
5-S-GAD, a novel radical scavenging compound, prevents lens opacity development.
Topics: alpha-Crystallins; Animals; Biphenyl Compounds; Carnosine; Cataract; Cells, Cultured; Chick Embryo; Cyclic N-Oxides; Diamide; Dihydroxyphenylalanine; Disease Progression; Dose-Response Relationship, Drug; Free Radical Scavengers; Galactose; Glucocorticoids; Glutathione; Insecta; Lens, Crystalline; Lipid Peroxidation; Male; Oxidative Stress; Picrates; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides | 2009 |
Chemopreventive and remediation effect of Hydrocotyl bonariensis Comm. Ex Lam (Apiaceae) leave extract in galactose-induced cataract.
Topics: Animals; Antioxidants; Apiaceae; Cataract; Galactose; Lens, Crystalline; Lipid Peroxidation; Male; Plant Extracts; Plant Leaves; Rats; Rats, Wistar | 2009 |
[Inhibition effect of epalrestat on rat lens osmotic expansion].
Topics: Aldehyde Reductase; Animals; Aquaporin 1; Cataract; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Galactose; Lens, Crystalline; Male; Osmosis; Rats; Rats, Sprague-Dawley; Rhodanine; RNA, Messenger; Thiazolidines | 2009 |
Oxidative stress in lens in vivo: inhibitory effect of caffeine. A preliminary report.
Topics: Adenosine Triphosphate; Animals; Caffeine; Cataract; Galactitol; Galactose; Glutathione; Lens, Crystalline; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2010 |
Evaluation of calcium dobesilate for its anti-cataract potential in experimental animal models.
Topics: Administration, Oral; Administration, Topical; Aldehyde Reductase; Animals; Calcium Dobesilate; Cataract; Chick Embryo; Disease Models, Animal; Female; Galactose; Hemostatics; Hydrocortisone; Male; Ophthalmic Solutions; Oxidative Stress; Rabbits; Rats; Rats, Wistar; Sodium Selenite | 2010 |
GALACTOSEMIA associated with cataracts in an infant.
Topics: Blood; Cataract; Child; Galactose; Galactosemias; Humans; Infant | 1946 |
Effectiveness of topical caffeine in cataract prevention: studies with galactose cataract.
Topics: Administration, Topical; Animals; Apoptosis; Aqueous Humor; Caffeine; Cataract; Galactose; Glutathione; Lens, Crystalline; Rats | 2010 |
Inhibitory effects of chlorogenic acid on aldose reductase activity in vitro and cataractogenesis in galactose-fed rats.
Topics: Aldehyde Reductase; Animals; Cataract; Cell Membrane; Chlorogenic Acid; Diabetes Complications; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Eye Proteins; Galactose; Hypoglycemic Agents; Immunohistochemistry; Lens Cortex, Crystalline; Lens, Crystalline; Male; Microscopy, Fluorescence; Quinic Acid; Random Allocation; Rats; Rats, Sprague-Dawley | 2011 |
Early cataract formation due to galactokinase deficiency: impact of newborn screening.
Topics: Cataract; Diet; False Negative Reactions; False Positive Reactions; Galactokinase; Galactose; Humans; Infant, Newborn; Neonatal Screening | 2011 |
Osmotic stress, not aldose reductase activity, directly induces growth factors and MAPK signaling changes during sugar cataract formation.
Topics: Aldehyde Reductase; Animals; Blotting, Western; Cataract; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Fibroblast Growth Factor 2; Galactose; Glucose; Glutathione; Hyperglycemia; Lens, Crystalline; Male; MAP Kinase Signaling System; Organ Culture Techniques; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Sorbitol; Stress, Physiological; Transforming Growth Factor beta | 2012 |
Evaluation of pharmacological activities and assessment of intraocular penetration of an ayurvedic polyherbal eye drop (Itone™) in experimental models.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Aqueous Humor; Biphenyl Compounds; Blood Vessels; Carrageenan; Cataract; Chick Embryo; Cornea; Edema; Eye; Female; Galactose; HeLa Cells; Humans; Hydrocortisone; Inflammation; Lens, Crystalline; Leukocytes; Leukotriene B4; Male; Medicine, Ayurvedic; Models, Animal; Ophthalmic Solutions; Phytotherapy; Picrates; Plant Extracts; Rabbits; Rats; Rats, Wistar; Sodium Selenite; Steroids; Vascular Endothelial Growth Factor A | 2013 |
Lycopene prevents sugar-induced morphological changes and modulates antioxidant status of human lens epithelial cells.
Topics: Antioxidants; Carotenoids; Catalase; Cataract; Cells, Cultured; Epithelial Cells; Galactose; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Humans; Lens, Crystalline; Lycopene; Malondialdehyde; Microscopy, Electron | 2002 |
Vitamin C metabolomic mapping in the lens with 6-deoxy-6-fluoro-ascorbic acid and high-resolution 19F-NMR spectroscopy.
Topics: 2,3-Diketogulonic Acid; Adult; Aged; Animals; Ascorbic Acid; Biological Transport; Buthionine Sulfoximine; Cataract; Cell Culture Techniques; Cytochalasin B; Dehydroascorbic Acid; Enzyme Inhibitors; Epithelial Cells; Fluorine Radioisotopes; Galactose; Glucose; Glutathione; Humans; Hyperglycemia; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Middle Aged; Organ Culture Techniques; Oxidative Stress; Rabbits; Rats; Rats, Sprague-Dawley | 2003 |
Effect of curcumin on galactose-induced cataractogenesis in rats.
Topics: Aldehyde Reductase; Animals; Antioxidants; Body Weight; Cataract; Chromatography, Gel; Chromatography, High Pressure Liquid; Crystallins; Curcumin; Disease Models, Animal; Eating; Galactose; Glutathione; Glycation End Products, Advanced; L-Iditol 2-Dehydrogenase; Lens, Crystalline; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2003 |
Apoptotic cell death in the lens epithelium of rat sugar cataract.
Topics: Aldehyde Reductase; Animals; Apoptosis; Blotting, Western; Cataract; DNA Fragmentation; Epithelial Cells; Galactitol; Galactose; Genes, p53; Imidazoles; Imidazolidines; In Situ Nick-End Labeling; Lens, Crystalline; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53 | 2003 |
Lycopene attenuates oxidative stress induced experimental cataract development: an in vitro and in vivo study.
Topics: Animals; Antioxidants; Carotenoids; Cataract; Female; Galactose; Glutathione; Incidence; Lens, Crystalline; Lycopene; Male; Malondialdehyde; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Wistar; Sodium Selenite | 2003 |
Cataracts in galactosemia; observations in three cases.
Topics: Cataract; Galactose; Galactosemias; Humans | 1953 |
[A biochemical aspect of the crystalline lens of the rat during a diet rich in galactose and in alloxan diabetes].
Topics: Animals; Cataract; Coenzymes; Diabetes Mellitus, Experimental; Diet; Galactose; Lens, Crystalline; Rats | 1953 |
Galactose cataracts.
Topics: Cataract; Galactose; Humans | 1953 |
Cataracts in galactosemia.
Topics: Cataract; Child; Galactose; Galactosemias; Humans; Infant | 1953 |
Cataracts in galactosaemia.
Topics: Cataract; Child; Galactose; Galactosemias; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases | 1953 |
[Pathogenesis of lactose cataract in rat].
Topics: Animals; Cataract; Galactose; Lactose; Rats | 1953 |
Hyperglycemia and galactose cataracts.
Topics: Blood Glucose; Cataract; Galactose; Humans; Hyperglycemia | 1954 |
Effect of cocarboxylase on the development of galactose cataract in rats.
Topics: Animals; Cataract; Galactose; Rats; Thiamine Pyrophosphate | 1955 |
Galactose 1-phosphate in galactose cataract.
Topics: Cataract; Galactose; Galactosephosphates; Hexosephosphates; Humans; Lens, Crystalline; Phosphates | 1955 |
[Experimental cataracts caused by galactose in rats; an attempt of medical treatment].
Topics: Animals; Cataract; Galactose; Rats | 1954 |
[Cataract of polyepiphyseal chondrodystrophic calcinosis in fetus (stippled epiphysis disease); cataract caused by galactosemia].
Topics: Achondroplasia; Blood; Calcinosis; Cataract; Child; Enchondromatosis; Epiphyses; Fetus; Galactose; Galactosemias; Humans; Infant; Osteochondrodysplasias | 1954 |
Proteins and protein synthesis in rat lenses with galactose cataract.
Topics: Animals; Cataract; Galactose; Protein Biosynthesis; Proteins; Rats | 1956 |
Studies on protein and protein synthesis.
Topics: Cataract; Galactose; Proteins | 1957 |
Galactosemic cataracts.
Topics: Cataract; Child; Galactose; Humans; Infant | 1957 |
Cataracts in galactosemia.
Topics: Cataract; Child; Galactose; Galactosemias; Humans; Infant | 1958 |
Two cases of galactose cataract and a biochemical-ophthalmological survey.
Topics: Cataract; Data Collection; Galactose; Humans; Ophthalmology | 1958 |
Electrolyte composition of experimental galactose cataracts.
Topics: Cataract; Electrolytes; Galactose | 1959 |
Studies on galactose cataract formation utilizing thymidine-tritium.
Topics: Cataract; Galactose; Nucleosides; Nucleotides; Thymidine; Tritium | 1960 |
Lens sodium and potassium concentrations during galactose induced cataractogenesis.
Topics: Cataract; Galactose; Lens, Crystalline; Potassium; Sodium; Sodium, Dietary | 1961 |
Pathogenetic factors in experimental galactose cataract. IV.
Topics: Cataract; Diet; Galactose; Nutrition Assessment | 1961 |
[Clinical contribution to the study of galactosemic cataract].
Topics: Cataract; Galactose; Humans | 1960 |
[Action of sulfadiazine on experimental galactose-induced cataract].
Topics: Cataract; Galactose; Sulfadiazine; Sulfanilamide; Sulfanilamides; Sulfonamides | 1960 |
ENZYME changes in galactose cataract.
Topics: Cataract; Galactose; Humans; Oxidoreductases | 1960 |
Hypophysectomy effect on lens epithelium mitosis and galactose cataract development in rats.
Topics: Animals; Cataract; Cell Division; Galactose; Hypophysectomy; Lens, Crystalline; Mitosis; Rats | 1962 |
[Galactosemic cataract].
Topics: Cataract; Galactose; Humans | 1961 |
[Initial anomalies of glucide metabolism in experimental cataract induced by galactose overload].
Topics: Carbohydrate Metabolism; Cataract; Galactose; Glucose; Glycogen | 1962 |
[Apropos of the galactose cataract].
Topics: Cataract; Galactose; Galactosemias; Humans | 1962 |
Experimental carbohydrate cataracts.
Topics: Caseins; Cataract; Diabetes Mellitus; Diet, Diabetic; Galactose | 1962 |
[Observations on the action of insulin therapy on experimental galactose-induced cataract].
Topics: Cataract; Galactose; Insulin | 1962 |
[Observations on the action of orotic acid on experimental galactose-induced cataract].
Topics: Cataract; Galactose; Humans; Orotic Acid | 1962 |
Observations on cataract formation in the newborn offspring of rats fed a high-galactose diet.
Topics: Animals; Animals, Newborn; Cataract; Diet; Female; Galactose; Humans; Maternal-Fetal Exchange; Pregnancy; Rats | 1963 |
Osmotic changes in experimental galactose cataracts.
Topics: Cataract; Diabetes Mellitus; Galactose; Osmosis | 1962 |
INHIBITION OF ACTION OF LENS MUTAROTASE ON GLUCOSE BY CATARACTOGENIC SUGARS AND CORRESPONDING POLYOLS.
Topics: Alcohols; Animals; Arabinose; Carbohydrate Epimerases; Carbohydrates; Cataract; Cattle; Dogs; Enzyme Inhibitors; Fructose; Galactose; Glucose; Isomerases; Lens, Crystalline; Mannose; Polymers; Rabbits; Rats; Research; Sorbitol; Spectrophotometry; Xylose | 1963 |
NUCLEIC ACID METABOLISM IN THE LENS. II. RIBONUCLEASE ACTIVITY AND RNA TURNOVER.
Topics: Adenine; Animals; Carbon Isotopes; Cataract; Diabetes Mellitus, Experimental; Galactose; Lens, Crystalline; Liver; Metabolism; Nucleotides; Phosphates; Phosphorus Isotopes; Radiation Injuries; Radiation Injuries, Experimental; Rats; Research; Ribonucleases; RNA; Sharks; Xylose; Yeasts | 1963 |
GLYCOPROTEINS OF THE LENS IN RELATION TO AGE AND CATARACT FORMATION. III. DIFFERENCES IN COMPOSITION AND DISTRIBUTION OF THE CARBOHYDRATE OF GLYCOPROTEIN OF LENS FIBERS IN DIFFERENT REGIONS OF THE LENS.
Topics: Aging; Animals; Carbohydrate Metabolism; Carbohydrates; Cataract; Cattle; Fucose; Galactose; Glycoproteins; Hexosamines; Lens, Crystalline; Mannose; Neuraminic Acids; Rabbits; Research | 1963 |
SYNTHESIS OF CREATINE PHOSPHATE BY THE CRYSTALLINE LENS; IN NORMAL CONDITIONS AND DURING THE DEVELOPMENT OF GALACTOSE CATARACT.
Topics: Adenosine Triphosphate; Cataract; Coenzymes; Creatine; Creatinine; Eye Proteins; Galactose; Galactosemias; Lens, Crystalline; Magnesium; Metabolism; Phosphocreatine; Phosphotransferases; Rabbits; Rats; Research; Tissue Extracts | 1964 |
[ACTIVITY OF SOME ENZYMES ON THE CRYSTALLINE LENS OF NORMAL RATS OF DIFFERENT AGES. GLUCOSE-6-PHOSPHATE DEHYDROGENASE AND ALDOLASE].
Topics: Aging; Carbohydrate Metabolism; Cataract; Diet; Fructose-Bisphosphate Aldolase; Galactose; Glucosephosphate Dehydrogenase; Lens, Crystalline; Pathology; Rats; Research | 1963 |
HYDRATION OF THE LENS DURING THE DEVELOPMENT OF GALACTOSE CATARACT.
Topics: Alcohols; Cataract; Dietary Carbohydrates; Electrolytes; Galactose; Glucose; Lens, Crystalline; Metabolism; Osmosis; Rats; Research; Sodium Chloride; Water | 1964 |
POINT OF IRREVERSIBILITY OF GALACTOSE CATARACTS IN THE RAT.
Topics: Adenosine Triphosphate; Cataract; Dietary Carbohydrates; Galactose; Galactosemias; Hexoses; Pathology; Pharmacology; Rats; Research; Toxicology | 1965 |
LENS ASSAYS ON DIABETIC AND GALACTOSEMIC RATS RECEIVING DIETS THAT MODIFY CATARACT DEVELOPMENT.
Topics: Amino Acids; Animals; Caseins; Cataract; Diabetes Mellitus, Experimental; Diet; Dietary Carbohydrates; Dietary Fats; Eye Proteins; Fructose; Galactose; Galactosemias; Glucose; Histocytochemistry; Hyperglycemia; Lens, Crystalline; Metabolism; Rats; Research; Sorbitol | 1965 |
CHANGES ASSOCIATED WITH THE APPEARANCE OF MATURE SUGAR CATARACTS.
Topics: Adenosine Triphosphate; Alcohols; Animals; Carbohydrates; Cataract; Diabetes Mellitus, Experimental; Fructose; Galactose; Glucose; Histocytochemistry; Lens, Crystalline; Rats; Research; Sorbitol | 1965 |
TRANSPLACENTAL GALACTOSE TOXICITY IN RATS.
Topics: Abnormalities, Drug-Induced; Animals, Newborn; Cataract; Eye; Female; Fetus; Galactose; Galactosemias; Histocytochemistry; Humans; Infant, Newborn; Kidney; Liver; Maternal-Fetal Exchange; Pathology; Pregnancy; Rats; Research; Toxicology | 1965 |
Galactosemia with cataracts; report of a case, with notes on physiopathology.
Topics: Aged; Cataract; Galactose; Galactosemias; Humans | 1955 |
Effect of blood supply on the development of cataracts.
Topics: Cardiovascular System; Cataract; Eye; Galactose; Humans | 1955 |
Response of three strains of albino rats to xylose and galactose.
Topics: Animals; Cataract; Galactose; Rats; Xylose | 1960 |
Pathogenetic factors in experimental galactose cataract. Part III.
Topics: Cataract; Galactose | 1960 |
Carbohydrate metabolism in the experimental galactose cataract.
Topics: Carbohydrate Metabolism; Cataract; Galactose | 1959 |
Enzymatic factors in experimental galactose cataract.
Topics: Animals; Cataract; Galactose; Glucosephosphate Dehydrogenase; Lens, Crystalline; Oxidation-Reduction; Oxidoreductases; Rats | 1959 |
Pathogenetic factors in experimental galactose cataract. Part I.
Topics: Cataract; Galactose; Humans | 1960 |
Pathogenetic factors in experimental galactose cataract. Part II.
Topics: Cataract; Galactose; Humans | 1960 |
Modification of galactose-induced cataract by oral administration of sulfur compounds.
Topics: Administration, Oral; Cataract; Galactose; Sulfur Compounds | 1962 |
[The inhibitory effect of aldose reductase inhibitor for proliferation in the lens epithelial cells of rat sugar cataract].
Topics: Aldehyde Reductase; Animals; Cataract; Cell Division; Epithelial Cells; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Rats; Rats, Sprague-Dawley; Sugar Alcohols | 2003 |
Human galactosemia cataract; report of a case.
Topics: Cataract; Galactose; Galactosemias | 1951 |
Galactosemia cataract; report of a case.
Topics: Aged; Cataract; Galactose; Galactosemias; Humans | 1951 |
Galactose cataractogenesis; review of literature and case report.
Topics: Cataract; Galactose; Humans | 1952 |
Blood sugar levels and cataract in alloxan-treated, galactose-fed and xylose-fed weanling rats.
Topics: Alloxan; Animals; Blood Glucose; Cataract; Galactose; Rats; Xylose | 1951 |
Ophthalmoscopic and morphogenetic changes in rat lens induced by galactose: attenuation by pyruvate.
Topics: Animals; Cataract; Cell Differentiation; Cell Movement; Diet; Galactitol; Galactose; Lens, Crystalline; Ophthalmoscopy; Oxidative Stress; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2004 |
Antioxidant enzymes and peroxidation in galactogenic cataract.
Topics: Animals; Antioxidants; Cataract; Galactose; Lipid Peroxidation; Male; Rats; Rats, Sprague-Dawley | 2003 |
Cataract formation in a strain of rats selected for high oxidative stress.
Topics: Aging; Animals; Cataract; Cytoplasm; Disease Progression; DNA; Fourier Analysis; Galactose; Immunohistochemistry; Lens, Crystalline; Lipid Peroxidation; Microscopy, Electron; Models, Animal; Oxidative Stress; Rats; Rats, Inbred Strains; Rats, Wistar; Reactive Oxygen Species | 2004 |
Gene expression profiling of diabetic and galactosaemic cataractous rat lens by microarray analysis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cataract; Diabetes Mellitus, Experimental; DNA, Complementary; Down-Regulation; Galactose; Galactosemias; Gene Expression Profiling; Insulin-Like Growth Factor I; Intercellular Signaling Peptides and Proteins; Lens, Crystalline; NF-kappa B; Oligonucleotide Array Sequence Analysis; Peroxidases; Peroxiredoxins; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta; Up-Regulation | 2005 |
Bilateral nuclear cataracts as the first neonatal sign of Fanconi-Bickel syndrome.
Topics: Cataract; Fanconi Syndrome; Galactose; Glucose; Humans | 2006 |
The unfolded protein response in lens epithelial cells from galactosemic rat lenses.
Topics: Activating Transcription Factor 4; Animals; Apoptosis; Caspases; Cataract; Cells, Cultured; Crystallins; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Epithelial Cells; Female; Galactose; Galactosemias; Glutathione; Heat-Shock Proteins; Hyperglycemia; Hypoglycemia; Immunoblotting; In Situ Nick-End Labeling; Lens, Crystalline; Molecular Chaperones; Oxidative Stress; Protein Denaturation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Transcription Factor CHOP | 2006 |
Cumulative antioxidant defense against oxidative challenge in galactose-induced cataractogenesis in Wistar rats.
Topics: Animals; Antioxidants; Cataract; Curcumin; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Galactose; Glutathione; Glutathione Reductase; Lens, Crystalline; Lipid Peroxides; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E | 2006 |
Up-regulation of P-glycoprotein expression by osmotic stress in rat sugar cataract.
Topics: Aldehyde Reductase; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cataract; Cells, Cultured; Eye Proteins; Female; Galactose; Lens, Crystalline; Osmosis; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2007 |
Effect of the isoflavone genistein against galactose-induced cataracts in rats.
Topics: Animals; Blood Glucose; Cataract; Connexin 43; Diet; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Galactose; Genistein; Guanylate Cyclase; Immunohistochemistry; Lens, Crystalline; Male; Microscopy; Rats; Rats, Long-Evans; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Somatostatin; Testosterone | 2007 |
Topical aldose reductase inhibitor formulations for effective lens drug delivery in a rat model for sugar cataracts.
Topics: Administration, Topical; Aldehyde Reductase; Animals; Aqueous Humor; Biological Availability; Biological Transport; Cataract; Cornea; Drug Carriers; Enzyme Inhibitors; Galactose; Hydrogen-Ion Concentration; Imidazolidines; Lens, Crystalline; Male; Mydriasis; Ophthalmic Solutions; Pharmaceutical Vehicles; Rats; Rats, Sprague-Dawley; Vacuoles; Viscosity | 2007 |
Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats.
Topics: Animals; Body Weight; Cataract; Cell Death; Cell Survival; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum; Epithelial Cells; Galactose; Galactosemias; Humans; Lens, Crystalline; Methylamines; Phenylbutyrates; Protein Folding; Rats; Rats, Sprague-Dawley; Sodium Selenite; Taurochenodeoxycholic Acid; Tunicamycin; Up-Regulation | 2007 |
Potential use of hirudin in diabetic cataract: a study of galactose mediated human lens epithelial cells injury.
Topics: Catalase; Cataract; Cell Line; Cell Proliferation; Epithelial Cells; Fibrinolytic Agents; Formazans; Galactose; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hirudins; Humans; Lens, Crystalline; Malondialdehyde; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Recombinant Proteins; Superoxide Dismutase; Tetrazolium Salts | 2008 |
[Inital histochemical findings in galactose cataract of albino rats].
Topics: Adenosine Triphosphate; Animals; Cataract; Galactose; Glucosephosphate Dehydrogenase; Histocytochemistry; Lens, Crystalline; Rats | 1966 |
Enzymes of carbohydrate metabolism in developing galactose cataracts of rats.
Topics: Animals; Carbohydrate Metabolism; Cataract; Eye Proteins; Fructose-Bisphosphate Aldolase; Galactose; Glucosephosphate Dehydrogenase; Glycerolphosphate Dehydrogenase; L-Lactate Dehydrogenase; Lens, Crystalline; Malate Dehydrogenase; Rats | 1967 |
Cataracts and galactose metabolism.
Topics: Age Factors; Animals; Body Weight; Carbohydrate Metabolism; Cataract; Diet; Galactose; Galactosemias; Genes, Recessive; Humans; Metabolism, Inborn Errors; Rats; Retina; Time Factors; Transferases | 1967 |
35S-methionine incorporation in rat lenses in media simulating cataractogenic conditions.
Topics: Animals; Cataract; Culture Media; Dietary Carbohydrates; DNA; Eye Proteins; Galactose; In Vitro Techniques; Lens, Crystalline; Male; Methionine; Osmolar Concentration; Potassium; Rats; Rats, Inbred Strains; RNA | 1983 |
Sodium-potassium--dependent ATPase. II. Cytochemical localization during the reversal of galactose cataracts in rat.
Topics: Animals; Cataract; Diet; Female; Galactose; Histocytochemistry; Lens, Crystalline; Microscopy, Electron; Rats; Remission, Spontaneous; Sodium-Potassium-Exchanging ATPase | 1980 |
Sodium-potassium-dependent ATPase. I. Cytochemical localization in normal and cataractous rat lenses.
Topics: Animals; Cataract; Diet; Female; Galactose; Histocytochemistry; Lens, Crystalline; Nitrophenols; Organophosphorus Compounds; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase | 1980 |
Biochemistry of the lens and cataractogenesis: current concepts.
Topics: Amino Acids; Animals; Biological Transport, Active; Cataract; Chickens; Citric Acid Cycle; Crystallins; Dogs; Galactose; Glutathione; Glycolysis; Hexokinase; Humans; Lens, Crystalline; Mice; Pentosephosphates; Phosphofructokinase-1; Rabbits; Rats; Sodium-Potassium-Exchanging ATPase; Ultraviolet Rays | 1980 |
Lipid composition and (Na+ + K+)-ATPase activity in rat lens during triparanol-induced cataract formation.
Topics: Animals; Cataract; Galactose; Humans; Kinetics; Lens, Crystalline; Lipid Metabolism; Phospholipids; Rats; Reference Values; Sodium-Potassium-Exchanging ATPase; Sterols; Triparanol | 1981 |
Cataracts related to enzymes of galactose metabolism.
Topics: Aged; Cataract; Female; Galactokinase; Galactose; Galactosemias; Heterozygote; HLA Antigens; Humans; Male; Nucleotidyltransferases; Pedigree; UTP-Hexose-1-Phosphate Uridylyltransferase | 1981 |
Inhibition of galactose-induced alterations in ocular lens with sorbinil.
Topics: 4-Nitrophenylphosphatase; Aldehyde Reductase; Animals; Cataract; Female; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Microscopy, Electron; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1983 |
Sugar cataracts in Mongolian gerbil (Meriones unguiculatus).
Topics: Aldehyde Reductase; Animals; Cataract; Disease Models, Animal; Galactitol; Galactose; Gerbillinae; Lens, Crystalline; Rats; Rats, Inbred Strains | 1983 |
Cytoarchitectural changes in lens epithelium of galactose-fed rats.
Topics: Animals; Cataract; Diet; Epithelium; Female; Galactose; Lens, Crystalline; Rats; Rats, Inbred Strains | 1984 |
Aspirin in experimental cataractogenesis.
Topics: Animals; Aspirin; Cataract; Disease Models, Animal; Female; Galactose; Male; Naphthalenes; Rabbits; Rats | 1984 |
Prevention of experimental cataract by alpha-tocopherol.
Topics: Animals; Cataract; Galactose; Naphthalenes; Rabbits; Rats; Vitamin E | 1984 |
Electrolyte pattern in experimental sugar cataracts in vitro.
Topics: Animals; Cataract; Electrolytes; Galactose; Glucose; Goats; Organ Culture Techniques | 1983 |
S-(1,2-dicarboxyethyl)glutathione and S-(1,2-dicarboxyethyl)L-cysteine in lens.
Topics: Animals; Cataract; Cattle; Chromatography, High Pressure Liquid; Cysteine; Dinitrofluorobenzene; Dogs; Galactose; Glutathione; Guinea Pigs; Lens, Crystalline; Rabbits; Rats; Species Specificity; Tuna | 1984 |
Distribution of taurine in the crystalline lens of vertebrate species and in cataractogenesis.
Topics: Animals; Cataract; Chickens; Galactose; Humans; Lens Capsule, Crystalline; Lens Cortex, Crystalline; Lens, Crystalline; Macaca mulatta; Rabbits; Ranidae; Rats; Rats, Inbred Strains; Taurine | 1983 |
Scanning electron microscopy of X-ray-induced cataract in mice on normal and galactose diet.
Topics: Animals; Cataract; Diet; Female; Galactose; Mice; Mice, Inbred Strains; Microscopy, Electron, Scanning; X-Rays | 1983 |
[Role of active oxygen in cataract formation in galactose-fed rats].
Topics: Animals; Cataract; Galactose; Glutathione Peroxidase; Lipid Peroxides; Male; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1984 |
Galactose cataract prevention with sorbinil, an aldose reductase inhibitor: a light microscopic study.
Topics: Aldehyde Reductase; Animals; Cataract; Galactose; Imidazoles; Imidazolidines; Male; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases | 1982 |
A geographic approach to senile cataracts: possible links with milk consumption, lactase activity, and galactose metabolism.
Topics: Adult; Aged; Animals; Asia; beta-Galactosidase; Cataract; Dairy Products; Female; Galactitol; Galactose; Galactosidases; Humans; Infant; Infant, Newborn; Lactose; Male; Marsupialia; Middle Aged; Milk; Mutation; Rats | 1982 |
Aldose reductase and the etiology of diabetic cataracts.
Topics: Adolescent; Adult; Aldehyde Reductase; Animals; Cataract; Child; Child, Preschool; Diabetes Complications; Diabetes Mellitus, Experimental; Dogs; Flavonoids; Galactose; Glucose; Humans; Mutation; Rats; Sorbitol; Sugar Alcohol Dehydrogenases | 1980 |
Xanthone-2-carboxylic acid effect on lens growth, hydration and proteins during diabetic cataract development.
Topics: Aldehyde Reductase; Animals; Animals, Newborn; Body Water; Cataract; Crystallins; Diabetes Mellitus, Experimental; Galactose; Lens, Crystalline; Rats; Sugar Alcohol Dehydrogenases; Xanthenes; Xanthones | 1982 |
Distribution of salicylate in lens and intraocular fluids and its effect on cataract formation.
Topics: Animals; Aqueous Humor; Aspirin; Cataract; Crystallins; Diabetes Complications; Galactose; Humans; Lens, Crystalline; Rabbits; Rats; Salicylates; Sodium Salicylate; Vitreous Body | 1983 |
Partial galactose disorders in families with premature cataracts.
Topics: Adolescent; Adult; Cataract; Child; Child, Preschool; Drug Tolerance; Erythrocytes; Female; Galactokinase; Galactose; Heterozygote; Humans; Infant; Isoelectric Focusing; Male; Middle Aged; Pregnancy; Pregnancy Complications; UTP-Hexose-1-Phosphate Uridylyltransferase | 1983 |
Crystallin synthesis and crystallin mRNAs in galactosemic rat lenses.
Topics: Animals; Cataract; Crystallins; Culture Techniques; Electrophoresis, Polyacrylamide Gel; Galactose; Isoelectric Focusing; Rats; Rats, Inbred Strains; RNA, Messenger; Time Factors | 1982 |
Dynamic changes in the organophosphate profile of the experimental galactose-induced cataract.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cataract; Galactose; Glycerophosphates; Half-Life; Lens, Crystalline; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Rabbits; Uridine Diphosphate Galactose | 1982 |
Acid phosphatase. I. Cytochemical localization in lenses of normal and galactose-fed rats.
Topics: Acid Phosphatase; Animals; Cataract; Dietary Carbohydrates; Female; Galactose; Histocytochemistry; Lens, Crystalline; Microscopy, Electron; Rats; Rats, Inbred Strains | 1982 |
Galactose intolerance and the risk of cataract.
Topics: Carbohydrate Metabolism, Inborn Errors; Cataract; Child; Female; Galactokinase; Galactose; Humans; Risk; UTP-Hexose-1-Phosphate Uridylyltransferase | 1982 |
Effect of prolactin on galactose-induced cataractogenesis in the rat.
Topics: Animals; Cataract; Female; Galactose; Male; Prolactin; Rats; Rats, Inbred Strains; Sex Factors; Time Factors | 1982 |
Role of nonenzymatic glycosylation in experimental cataract formation.
Topics: Animals; Cataract; Disease Models, Animal; Galactose; Galactosemias; Glycoproteins; Imidazoles; Imidazolidines; Lens, Crystalline; Proteins; Rats | 1980 |
Regional analyses of the opaque galactose cataract and the reversal process.
Topics: Animals; Cataract; Diet; Female; Galactose; Lens, Crystalline; Male; Microscopy, Electron, Scanning; Rats | 1980 |
Effect of germanium-132 on galactose cataracts and glycation in rats.
Topics: Animals; Cataract; Galactose; Germanium; Glycosylation; Lens, Crystalline; Microscopy, Electron, Scanning; Organometallic Compounds; Propionates; Rats; Rats, Sprague-Dawley | 1995 |
Sorbinil prevention of diabetic-like retinopathy in the galactose-fed rat model.
Topics: Aldehyde Reductase; Animals; Capillaries; Cataract; Diabetic Retinopathy; Disease Models, Animal; Enzyme Inhibitors; Galactose; Image Processing, Computer-Assisted; Imidazoles; Imidazolidines; Male; Rats; Rats, Sprague-Dawley; Retinal Vessels | 1995 |
Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.
Topics: Aldehyde Reductase; Animals; Blotting, Southern; Cataract; Crosses, Genetic; Diabetes Mellitus, Experimental; Diabetic Retinopathy; DNA, Complementary; Female; Galactitol; Galactose; Galactosemias; Genotype; Humans; Lens, Crystalline; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Polymerase Chain Reaction | 1995 |
Dose-response characteristics of galactose-induced cataract in the rat.
Topics: Animals; Body Weight; Cataract; Diet; Dose-Response Relationship, Drug; Galactose; Lens, Crystalline; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Proteolysis by calpain is an underlying mechanism for formation of sugar cataract in rat lens.
Topics: Aldehyde Reductase; Animals; Benzothiazoles; Body Water; Calcium; Calpain; Cataract; Crystallins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Galactose; Lens, Crystalline; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Thiazines; Thiazoles; Xylose | 1995 |
[Laser Raman spectrometry study on experimental galactose-induced cataract].
Topics: Animals; Cataract; Female; Galactose; Lens, Crystalline; Male; Potassium; Rats; Rats, Wistar; Sodium; Spectrum Analysis, Raman | 1994 |
Assessment of sulfhydryl group in individual rat lens protein subunits during galactose cataract development.
Topics: Animals; Cataract; Crystallins; Galactose; Lens, Crystalline; Male; Maleimides; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sulfhydryl Compounds; Sulfhydryl Reagents | 1994 |
Galactose-induced retinal microangiopathy in rats.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Cataract; Diabetic Retinopathy; Disease Models, Animal; Erythrocytes; Galactitol; Galactose; Galactosemias; Imidazoles; Imidazolidines; Male; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; Sciatic Nerve | 1995 |
Amelioration of diabetes-like retinal changes in galactose-fed dogs.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetic Retinopathy; Dogs; Dose-Response Relationship, Drug; Galactose; Imidazoles; Imidazolidines; Male; Retina; Retinal Vessels | 1994 |
Diabeteslike proliferative retinal changes in galactose-fed dogs.
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Dogs; Galactose; Hyperglycemia; Male; Retina; Retinal Neovascularization; Retinal Vessels; Vitreous Hemorrhage | 1995 |
Aldose reductase inhibitors and galactose toxicity in neonatal and maternal rat lenses.
Topics: Aldehyde Reductase; Animals; Animals, Newborn; Cataract; Female; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Sprague-Dawley | 1993 |
Galactose-induced cataract formation in guinea pigs: morphologic changes and accumulation of galactitol.
Topics: Animals; Cataract; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Galactitol; Galactose; Guinea Pigs; Inositol; Lens, Crystalline; Male; Rats | 1994 |
A physiological level of ascorbate inhibits galactose cataract in guinea pigs by decreasing polyol accumulation in the lens epithelium: a dehydroascorbate-linked mechanism.
Topics: Animals; Aqueous Humor; Ascorbic Acid; Cataract; Cells, Cultured; Dehydroascorbic Acid; Dogs; Female; Galactitol; Galactose; Glutathione; Guinea Pigs; Hydrogen Peroxide; Inositol; Lens, Crystalline; NADP; Sodium-Potassium-Exchanging ATPase | 1994 |
Alteration of crystallin polypeptides in rat lenses during the development of galactose-induced cataract.
Topics: Animals; Cataract; Crystallins; Galactose; Lens, Crystalline; Peptide Fragments; Rats; Rats, Sprague-Dawley | 1993 |
Elemental studies in rat lens during galactose cataract reversal.
Topics: Animals; Cataract; Cations; Diet; Disease Models, Animal; Electron Probe Microanalysis; Female; Galactose; Lens, Crystalline; Rats; Rats, Sprague-Dawley | 1993 |
Quantitative analysis of retinal vessel changes in galactose-fed dogs.
Topics: Aldehyde Reductase; Animals; Cataract; Cell Count; Diabetic Retinopathy; Dogs; Endothelium, Vascular; Galactose; Image Processing, Computer-Assisted; Imidazoles; Imidazolidines; Male; Retinal Vessels | 1993 |
Inhibition of in utero galactose-induced cataract development by an aldose reductase inhibitor in rat--electron microscopic study.
Topics: Aldehyde Reductase; Animals; Animals, Newborn; Cataract; Female; Fetal Diseases; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Pregnancy; Rats; Rats, Sprague-Dawley; Vacuoles | 1993 |
[Magnetic resonance imaging study on rat sugar cataract].
Topics: Aldehyde Reductase; Animals; Body Water; Cataract; Disease Models, Animal; Galactose; Lens, Crystalline; Magnetic Resonance Imaging; Male; Rats; Rats, Sprague-Dawley | 1993 |
Phase separation inhibitors and lens transparency.
Topics: Amifostine; Animals; Cataract; Disease Models, Animal; Female; Galactose; Lens, Crystalline; Male; Radiation Injuries, Experimental; Radiation-Sensitizing Agents; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Sodium Selenite; Streptozocin | 1993 |
[Prefeeding of aldose reductase inhibitor inhibits galactose cataract].
Topics: Aldehyde Reductase; Animals; Cataract; Crystallins; Galactitol; Galactose; Premedication; Quinazolines; Rats; Rats, Sprague-Dawley | 1993 |
Protein kinase C in galactosemic and tolrestat-treated lens epithelial cells.
Topics: Aldehyde Reductase; Amino Acid Sequence; Animals; Blotting, Western; Cataract; Cattle; Cells, Cultured; Culture Media; Epithelium; Galactose; Isoenzymes; Lens, Crystalline; Molecular Sequence Data; Naphthalenes; Peptides; Protein Kinase C | 1993 |
Proliferative changes of lens epithelial cells in rat and mouse galactose cataracts--examination using whole-mount preparations.
Topics: Animals; Autoradiography; Cataract; Cell Division; Dietary Carbohydrates; Disease Models, Animal; Epithelium; Galactose; Galactosemias; Lens, Crystalline; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; Thymidine | 1993 |
Effect of pregnancy on development of galactose-induced cataract in rat.
Topics: Animals; Cataract; Dietary Carbohydrates; Female; Galactitol; Galactose; Galactosemias; Incidence; Lens, Crystalline; Male; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 1993 |
Disturbed galactose metabolism in elderly and diabetic humans is associated with cataract formation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Case-Control Studies; Cataract; Diabetes Complications; Diabetes Mellitus; Digestion; Eating; Erythrocytes; Female; Galactokinase; Galactose; Humans; Lactose; Lactose Intolerance; Male; Middle Aged; Milk; Odds Ratio; Retrospective Studies; Risk Factors; UTP-Hexose-1-Phosphate Uridylyltransferase; Yogurt | 1993 |
[Cell kinetics of rat lens epithelium by cytofluorometric nuclear DNA determination].
Topics: Animals; Cataract; Cell Division; DNA; Epithelial Cells; Epithelium; Flow Cytometry; Galactose; Lens, Crystalline; Male; Rats; Rats, Sprague-Dawley | 1995 |
[Prevention of galactose-induced cataractogenesis in rats by salvianolic acid A].
Topics: Aldehyde Reductase; Animals; Caffeic Acids; Cataract; Drugs, Chinese Herbal; Female; Free Radical Scavengers; Galactose; Hydrogen Peroxide; Lactates; Lens, Crystalline; Male; Malondialdehyde; Random Allocation; Rats; Rats, Sprague-Dawley | 1995 |
Magnetic resonance imaging of the galactosemic dog eye using magnetization transfer contrast.
Topics: Animals; Cataract; Disease Models, Animal; Dogs; Galactose; Galactosemias; Lens, Crystalline; Magnetic Resonance Imaging; Male; Severity of Illness Index | 1995 |
Diabetic-like retinopathy ameliorated with the aldose reductase inhibitor WAY-121,509.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Cataract; Diabetic Retinopathy; Erythrocytes; Female; Galactitol; Galactose; Glycated Hemoglobin; Image Processing, Computer-Assisted; Lens, Crystalline; Polymers; Random Allocation; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels | 1996 |
Lens epithelial cell mRNA. III. Elevated expression of macrophage migration inhibitory factor mRNA in galactose cataracts.
Topics: Animals; Cataract; DNA, Complementary; Epithelial Cells; Epithelium; Female; Galactose; Gene Library; Lens, Crystalline; Macrophage Migration-Inhibitory Factors; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1996 |
Inhibition of naphthalene cataract in rats by aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Culture Techniques; Disease Models, Animal; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; Imidazoles; Imidazolidines; Male; Naphthalenes; Rats; Spiro Compounds | 1996 |
Delay or inhibition of rat lens opacification using pantethine and WR-77913.
Topics: Amifostine; Animals; Cataract; Female; Galactose; Lens, Crystalline; Male; Pantetheine; Protein Denaturation; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Sodium Selenite; Streptozocin | 1996 |
Liquefaction of cortical tissue in diabetic and galactosemic rat lenses defined by confocal laser scanning microscopy.
Topics: Animals; Cataract; Cell Membrane; Diabetes Mellitus, Experimental; Female; Galactose; Galactosemias; Lens Cortex, Crystalline; Microscopy, Confocal; Microtomy; Rats; Rats, Wistar; Streptozocin | 1996 |
Laser Raman spectrometry study on experimental galactose-induced cataract.
Topics: Animals; Cataract; Galactose; Lens Nucleus, Crystalline; Potassium; Rats; Rats, Wistar; Sodium; Spectrum Analysis, Raman | 1995 |
Quantitation of galactosemic cataracts in dogs using magnetization transfer contrast-enhanced magnetic resonance imaging.
Topics: Animals; Cataract; Disease Progression; Dogs; Galactose; Galactosemias; Lens, Crystalline; Magnetic Resonance Imaging; Male; Severity of Illness Index | 1996 |
NADH-coenzyme Q reductase (complex I) deficiency: heterogeneity in phenotype and biochemical findings.
Topics: Acidosis, Lactic; Adenosine Triphosphate; Cardiomyopathies; Cataract; Cell Line; Child; Child, Preschool; Fibroblasts; Galactose; Hepatomegaly; Humans; Infant; Infant, Newborn; Kidney Diseases; Leigh Disease; NAD(P)H Dehydrogenase (Quinone); Phenotype; Vitamin K | 1996 |
Indirect estimation of lens protein dynamics via magnetization transfer.
Topics: Animals; Cataract; Crystallins; Galactose; Lens, Crystalline; Magnetic Resonance Spectroscopy; Models, Chemical; Rats; Temperature | 1996 |
High galactose levels in vitro and in vivo impair ascorbate regeneration and increase ascorbate-mediated glycation in cultured rat lens.
Topics: 2,3-Diketogulonic Acid; Animals; Ascorbic Acid; Cataract; Crystallins; Dehydroascorbic Acid; Galactose; Humans; Lens, Crystalline; Male; Organ Culture Techniques; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Age-dependent lens changes in galactose-fed dogs.
Topics: Age Factors; Aging; Animals; Cataract; Disease Progression; Dogs; Galactose; NADH, NADPH Oxidoreductases | 1997 |
Effect of pretreatment of germanium-132 on Na(+)-K(+)-ATPase and galactose cataracts.
Topics: Animals; Antineoplastic Agents; Cataract; Galactose; Germanium; Glycosylation; Lens, Crystalline; Microscopy, Electron, Scanning; Ophthalmic Solutions; Organometallic Compounds; Propionates; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 1997 |
An aldose reductase inhibitor and aminoguanidine prevent vascular endothelial growth factor expression in rats with long-term galactosemia.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetic Retinopathy; Endothelial Growth Factors; Enzyme Inhibitors; Factor VIII; Female; Fluorescent Antibody Technique, Indirect; Galactose; Galactosemias; Glial Fibrillary Acidic Protein; Guanidines; Lymphokines; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vimentin | 1997 |
Dose-dependent reduction of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by the aldose reductase inhibitor M79175.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetic Retinopathy; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Galactose; Imidazoles; Imidazolidines; Male; Retinal Vessels; Trypsin | 1997 |
Preventive action of vitamin E-containing liposomes on cataractogenesis in young adult rats fed a 25% galactose diet.
Topics: Animals; Antioxidants; Cataract; Cholesterol; Drug Carriers; Galactose; Glutathione; Lens, Crystalline; Lipid Peroxidation; Liposomes; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Vitamin E | 1997 |
Dose-dependent prevention of sugar cataracts in galactose-fed dogs by the aldose reductase inhibitor M79175.
Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Galactose; Imidazoles; Imidazolidines; Male | 1998 |
Diabetic-like corneal sensitivity loss in galactose-fed rats ameliorated with aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Blinking; Cataract; Cornea; Diabetes Mellitus, Experimental; Diet; Enzyme Inhibitors; Fluorenes; Galactose; Galactosemias; Hydantoins; Male; Physical Stimulation; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones | 1998 |
Free lysine, glycine, alanine, glutamic acid and aspartic acid reduce the glycation of human lens proteins by galactose.
Topics: Adult; Amino Acids; Cataract; Crystallins; Galactose; Glucose; Glycosylation; Humans; In Vitro Techniques; Lysine; Middle Aged | 1997 |
The relationship between osmotic stress and calcium elevation: in vitro and in vivo rat lens models.
Topics: Animals; Calcium; Cataract; Culture Techniques; Galactose; Lens, Crystalline; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Sodium | 1998 |
Effects of xylose on monkey lenses in organ culture: a model for study of sugar cataracts in a primate.
Topics: Animals; Cataract; Disease Models, Animal; Galactitol; Galactose; Glucose; Lens, Crystalline; Macaca mulatta; Organ Culture Techniques; Phosphorylcholine; Sorbitol; Xylitol; Xylose | 1998 |
Galactosemic cataractogenesis disrupts intracellular interactions and changes the substrate specificity of choline/ethanolamine kinase.
Topics: Aged; Animals; Cataract; Cell Culture Techniques; Choline Kinase; Dogs; Epithelial Cells; Galactose; Humans; Lens, Crystalline; Macaca mulatta; Middle Aged; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pigment Epithelium of Eye; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Substrate Specificity; Swine | 1998 |
Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; L-Iditol 2-Dehydrogenase; Phthalazines; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley | 1998 |
Synthesis of 4-hydroxy-3(2H)-furanone acyl derivatives and their anti-cataract effect on spontaneous cataract rats (ICR/f).
Topics: Acylation; Animals; Cataract; Disease Susceptibility; Furans; Galactose; Hydrolysis; Linear Models; Molecular Weight; Rats; Rats, Inbred Strains | 1998 |
Inhibition of galactose-induced cataractogenesis by troglitazone, a new antidiabetic drug with an antioxidant property, in rat lens culture.
Topics: Aldehyde Reductase; Animals; Antioxidants; Cataract; Chromans; Galactitol; Galactose; Glutathione Peroxidase; Glutathione Reductase; Hypoglycemic Agents; Lens, Crystalline; Lipid Peroxides; NADP; Organ Culture Techniques; Organ Size; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone; Vacuoles | 1999 |
Cataract formation through the polyol pathway is associated with free radical production.
Topics: Aldehyde Reductase; Animals; Cataract; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Galactose; Hydroxyl Radical; Imidazoles; Imidazolidines; Male; Models, Biological; Polymers; Rats; Rats, Sprague-Dawley | 1999 |
Attenuation of galactose-induced cataract by pyruvate.
Topics: Adenosine Triphosphate; Animals; Aqueous Humor; Cataract; Diet; Galactose; Galactosemias; Glycoproteins; Glycosylation; Lens, Crystalline; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes | 1999 |
Preventive effect of topical vitamin E-containing liposome instillation on the progression of galactose cataract. Comparison between 5-week- and 12-week-old rats fed a 25% galactose diet.
Topics: Animals; Body Water; Cataract; Disease Progression; Drug Carriers; Galactitol; Galactose; Glutathione; Lens, Crystalline; Lipid Peroxides; Liposomes; Male; Rats; Rats, Wistar; Vitamin E | 1999 |
Cataract development in 12-month-old rats fed a 25% galactose diet and its relation to osmotic stress and oxidative damage.
Topics: Animals; Body Water; Cataract; Cholesterol; Crystallins; Diet; Galactitol; Galactose; Galactosemias; Glutathione; Lens, Crystalline; Lipid Peroxides; Male; Osmotic Pressure; Oxidative Stress; Rats; Rats, Wistar; Vitamin E | 1999 |
A new approach against sugar cataract through aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Enzyme Inhibitors; Galactitol; Galactose; Lens, Crystalline; Naphthalenes; Rats; Rats, Sprague-Dawley | 1999 |
Attenuation of sugar cataract by ethyl pyruvate.
Topics: Adenosine Triphosphate; Animals; Aqueous Humor; Cataract; Crystallins; Dietary Sucrose; Galactitol; Galactose; Galactosemias; Glycosylation; Male; Ophthalmic Solutions; Pyruvates; Rats; Rats, Sprague-Dawley | 1999 |
Organophosphate metabolic changes in the rat lens during the development of galactose-induced cataract.
Topics: Adenosine Triphosphate; Animals; Cataract; Galactose; Glycerophosphates; Histocytochemistry; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Phosphates; Phosphorus Radioisotopes; Phosphorylcholine; Rats; Rats, Wistar | 1999 |
Functional and structural studies of alpha-crystallin from galactosemic rat lenses.
Topics: Anilino Naphthalenesulfonates; Animals; Binding Sites; Cataract; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallins; Dithiothreitol; Female; Galactose; Galactosemias; Insulin; Lens, Crystalline; Molecular Chaperones; Molecular Weight; Protein Binding; Protein Conformation; Protein Denaturation; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Time Factors | 2000 |
A mouse model of galactose-induced cataracts.
Topics: Aldehyde Reductase; Animals; Base Sequence; Cataract; Disease Models, Animal; DNA, Complementary; Galactitol; Galactokinase; Galactose; Gene Expression; Gene Targeting; Humans; Mice; Mice, Knockout; Mice, Transgenic; Molecular Sequence Data; Oxidation-Reduction | 2000 |
Preventive effect of vitamin E-containing liposome instillation on cataract progression in 12-month-old rats fed a 25% galactose diet.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Body Water; Cataract; Cholesterol; Diet; Disease Progression; Drug Carriers; Galactitol; Galactose; Galactosemias; Glutathione; Lens, Crystalline; Lipid Peroxides; Liposomes; Male; Phosphatidylcholines; Rats; Rats, Wistar; Vitamin E | 2000 |
A genetic factor for age-related cataract: identification and characterization of a novel galactokinase variant, "Osaka," in Asians.
Topics: Adult; Age of Onset; Aging; Alleles; Amino Acid Substitution; Animals; Asian People; Base Sequence; Cataract; Child, Preschool; COS Cells; Female; Galactokinase; Galactose; Gene Frequency; Genetic Testing; Genetic Variation; Humans; Infant; Infant, Newborn; Japan; Kinetics; Korea; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree | 2001 |
[Early childhood cataract in hereditary UDP-galactose-4-epimerase deficiency--a case report].
Topics: Cataract; Child, Preschool; Galactose; Galactosemias; Genetic Predisposition to Disease; Heterozygote; Humans; Male; UDPglucose 4-Epimerase | 2001 |
The role of aldose reductase in sugar cataract formation: aldose reductase plays a key role in lens epithelial cell death (apoptosis).
Topics: Aldehyde Reductase; Animals; Apoptosis; Base Sequence; Cataract; Cells, Cultured; DNA Primers; Dogs; Enzyme Inhibitors; Epithelial Cells; Fluorenes; Galactitol; Galactose; Hydantoins; Lens, Crystalline; Sugar Alcohols | 2001 |
[The early biochemical changes of cataractous lenses of rats cultured in vitro].
Topics: Animals; Cataract; Female; Galactose; In Vitro Techniques; Lens, Crystalline; Male; Rats; Rats, Wistar; Sodium Selenite | 2000 |
[The experimental research of free calcium of the lens epithelial cells in galactose cataract].
Topics: Animals; Calcium; Cataract; Epithelial Cells; Female; Galactose; Lens, Crystalline; Male; Rats; Rats, Wistar | 1998 |
Increased expression of p21(WAF-1/CIP-1) in the lens epithelium of rat sugar cataract.
Topics: Animals; Biomarkers; Blotting, Southern; Cataract; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epithelial Cells; Galactose; Gene Expression; Immunohistochemistry; Lens, Crystalline; Male; Proliferating Cell Nuclear Antigen; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
CP-45,634: a novel aldose reductase inhibitor that inhibits polyol pathway activity in diabetic and galactosemic rats.
Topics: Aldehyde Reductase; Animals; Benzopyrans; Cataract; Chromans; Diabetes Mellitus, Experimental; Galactitol; Galactose; Galactosemias; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Male; Polymers; Rats; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases | 1979 |
[Activity of enzymes of galactose metabolism in so-called congenital cataract (author's transl)].
Topics: Austria; Cataract; Child; Child, Preschool; Diet Therapy; Galactose; Gene Frequency; Humans; Infant; Methods; Phosphotransferases | 1975 |
Galactose tolerance studies of individuals with reduced galactose pathway activity.
Topics: Cataract; Female; Galactose; Heterozygote; Humans; Infant, Newborn; Infusions, Parenteral; Phenotype; Phosphotransferases; Pregnancy | 1975 |
Galactose metabolism in relation to cataract formation in marsupials.
Topics: Adult; Age Factors; Animals; Cataract; Cattle; Disease Models, Animal; Erythrocytes; Galactose; Galactosemias; Humans; Macropodidae; Marsupialia; Milk; Phosphotransferases; UTP-Hexose-1-Phosphate Uridylyltransferase | 1975 |
[Galactokinase deficiency, cause of hereditary cataract. Recent publications].
Topics: Adolescent; Cataract; Child; Child, Preschool; Galactose; Galactosemias; Humans; Infant; Phosphotransferases | 1975 |
[Cataract due to galactokinase deficiency in a premature infant].
Topics: Cataract; Female; Galactose; Galactosemias; Humans; Infant, Newborn; Infant, Premature, Diseases; Phosphotransferases | 1976 |
Alterations of lens protein synthesis in galactosemic rats.
Topics: Animals; Cataract; Crystallins; Diet; Eye Proteins; Galactose; Galactosemias; Lens, Crystalline; Potassium; Rats; Sodium | 1979 |
Ultrastructural changes during the development and reversal of galactose cataracts.
Topics: Animals; Cataract; Female; Galactose; Lens, Crystalline; Microscopy, Electron; Rats; Remission, Spontaneous; Time Factors | 1978 |
Studies on the crystalline lens. XXVII. Kinetic and bioelectric measurements of galactose cataracts in rats.
Topics: Animals; Biological Transport, Active; Cataract; Chlorides; Female; Galactose; Membrane Potentials; Potassium; Rats; Sodium | 1978 |
Progressive galactose cataractogenesis and regional susceptibility in the neonatal lens.
Topics: Animals; Animals, Newborn; Cataract; Galactose; Lens, Crystalline; Microscopy, Electron, Scanning; Rats; Time Factors | 1978 |
Regional analyses of the reversal process in the neonatal galactose cataract.
Topics: Animals; Animals, Newborn; Cataract; Female; Galactose; Lens, Crystalline; Microscopy, Electron, Scanning; Rats; Time Factors | 1978 |
Characterization of lens proteins I. Identification of additional soluble fractions in rat lenses.
Topics: Animals; Cataract; Cattle; Crystallins; Electrophoresis, Disc; Galactose; Methods; Rats | 1977 |
Gas chromatographic study of free polyols and aldoses in cataractous human lens tissue.
Topics: Cataract; Chromatography, Gas; Diabetes Mellitus; Galactose; Glucose; Humans; Inositol; Lens, Crystalline; Sugar Alcohols; Xylose | 1976 |
Biochemical changes associated with the development and reversal of galactose cataracts.
Topics: Amino Acids; Animals; Cataract; Female; Galactitol; Galactose; Glutathione; Lens, Crystalline; Potassium; Rats; Sodium; Time Factors; Water | 1976 |
Tissue culture of rat lenses.
Topics: Animals; Cataract; Culture Media; Culture Techniques; Galactose; Lens, Crystalline; Male; Rats | 1976 |
Investigations on the influence of different corticosteroids on the development of galactose cataracts in rats.
Topics: Adrenal Cortex Hormones; Animals; Body Weight; Cataract; Desoxycorticosterone; Drug Synergism; Female; Fluocortolone; Galactose; Hydrocortisone; Prednisolone; Rats | 1976 |
[Galactose cataract and metabolic role of glutathione in lenses. I. The therapeutic effect of glutathione on galactose cataract (author's transl)].
Topics: Aged; Animals; Cataract; Galactose; Glutathione; Humans; In Vitro Techniques; Lens, Crystalline; Male; Rats | 1975 |
Nutrition of orphan marsupials.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Avitaminosis; Calcium; Carbohydrate Metabolism, Inborn Errors; Cataract; Disaccharides; Galactose; Lactose; Marsupialia; Milk; Weaning | 1975 |
Swelling of the lens fibers.
Topics: Animals; Cataract; Edema; Galactose; Lens, Crystalline; Mice; Mice, Inbred Strains; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Time Factors | 1975 |
Cataracts in early life: biochemistry.
Topics: Cataract; Diabetes Complications; Diabetes Mellitus; Galactose; Glucose; Hypocalcemia; Metabolism, Inborn Errors | 1976 |
Alterations in lens permeability during galactose cataract development in rat.
Topics: Animals; Cataract; Cell Membrane Permeability; Disease Models, Animal; Epithelium; Female; Galactose; Horseradish Peroxidase; Intercellular Junctions; Lanthanum; Lens Capsule, Crystalline; Lens, Crystalline; Rats; Rats, Inbred Strains; Ruthenium Red | 1992 |
Involvement of lipocortin I in development of galactose-induced cataracts in rat.
Topics: Animals; Annexins; Calcium-Binding Proteins; Cataract; Galactose; Lens, Crystalline; Male; Rats; Rats, Inbred Strains | 1992 |
Transient elevation of aldose reductase mRNA in lens of rats developing galactose cataracts.
Topics: Aldehyde Reductase; Animals; Cataract; Crystallins; Enzyme Induction; Epithelium; Eye Proteins; Female; Galactose; Galactosemias; Lens, Crystalline; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1992 |
Effect of aldose reductase inhibitors on lenticular dulcitol level in galactose fed rats.
Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Sprague-Dawley | 1992 |
Changes of urea-soluble and intrinsic membrane proteins in rat lenses during the formation of galactose cataract.
Topics: Animals; Cataract; Crystallins; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Galactose; Lens, Crystalline; Membrane Proteins; Molecular Weight; Rats; Rats, Sprague-Dawley; Solubility; Urea | 1992 |
Expression of c-myc protooncogene in rat lens cells during development, maturation and reversal of galactose cataracts.
Topics: Animals; Cataract; Epithelium; Female; Galactose; Galactosemias; Gene Expression; Genes, myc; Lens, Crystalline; Rats; Rats, Inbred Strains; RNA, Messenger | 1992 |
High-resolution MR imaging of water diffusion in the rabbit lens.
Topics: Animals; Body Water; Cataract; Diffusion; Female; Galactose; Lens, Crystalline; Magnetic Resonance Imaging; Male; Rabbits | 1992 |
Changes of glutathione and taurine concentrations in lenses of rat eyes induced by galactose-cataract formation or ageing.
Topics: Aging; Animals; Cataract; Female; Galactose; Glutathione; Lens, Crystalline; Rats; Rats, Inbred Strains; Taurine | 1992 |
[Galactose cataract].
Topics: Animals; Cataract; Disease Models, Animal; Galactose; Lens, Crystalline; Rats | 1992 |
[1H-NMR study on protein of normal and galactose cataractous rat whole lenses].
Topics: Animals; Cataract; Crystallins; Galactose; Hydrogen; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains | 1992 |
[Formation of congenital cataract in the offspring of galactosemic rats].
Topics: Administration, Oral; Animal Feed; Animals; Cataract; Female; Galactose; Galactosemias; Gestational Age; Pregnancy; Rats; Rats, Inbred Strains | 1992 |
[The metabolism of galactose cataracts evaluated by phosphorous-31 nuclear magnetic resonance spectroscopy (2)].
Topics: Animals; Cataract; Galactose; Lens, Crystalline; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Phosphorus; Rats; Rats, Inbred Lew | 1992 |
[Cell kinetics of lens epithelial cells on the whole-mount preparation (3). Changes in mouse cataract lens by feeding galactose].
Topics: Administration, Oral; Animal Feed; Animals; Cataract; Cell Cycle; Cytological Techniques; Epithelium; Galactose; Galactosemias; Lens, Crystalline; Mice; Mice, Inbred ICR | 1992 |
Myo-inositol transport in the lens of galactose-maintained rats.
Topics: Animals; Biological Transport, Active; Carbohydrate Metabolism; Cataract; Cell Membrane Permeability; Chromatography, Gas; Galactose; Inositol; Lens, Crystalline; Male; Polymers; Rats; Rats, Inbred Strains; Sorbitol | 1992 |
Prevention of galactose cataract by pyruvate.
Topics: Adenosine Triphosphate; Animals; Cataract; Crystallins; Diet; Disease Models, Animal; Galactitol; Galactose; Lens, Crystalline; Ophthalmic Solutions; Organ Culture Techniques; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol | 1992 |
Crystallin mRNA concentrations and distribution in lens of normal and galactosemic rats. Implications in development of sugar cataracts.
Topics: Animals; Autoradiography; Blotting, Northern; Cataract; Crystallins; Electrophoresis, Polyacrylamide Gel; Female; Galactose; Lens, Crystalline; Nucleic Acid Hybridization; Plasmids; Rats; Rats, Inbred Strains; RNA; RNA, Messenger | 1991 |
In utero and milk-mediated effect of aldose reductase inhibitor on galactose cataracts.
Topics: Aldehyde Reductase; Animals; Cataract; Female; Fetal Diseases; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Maternal-Fetal Exchange; Microscopy, Electron, Scanning; Milk, Human; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
Inhibition in rat of development of in utero galactose-induced cataract by an aldose reductase inhibitor--a light microscopic study.
Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Female; Fetal Diseases; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
Naphthol and lens.
Topics: Amino Acids; Animals; Cataract; Culture Media; Galactose; Lens, Crystalline; Naphthols; Potassium; Sheep | 1991 |
[Relation between metabolic and histological changes in the rat lens during the pathogenesis of galactose cataract].
Topics: Animals; Cataract; Galactose; Lens, Crystalline; Organophosphorus Compounds; Rats; Rats, Inbred Strains | 1991 |
Glycation-induced crosslinking of calf lens crystallins.
Topics: Animals; Cataract; Cattle; Chromatography, Gel; Crystallins; Electrophoresis, Polyacrylamide Gel; Galactose; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glycosylation; In Vitro Techniques; Molecular Weight; Protein Denaturation | 1991 |
Progression of sugar cataract in the dog.
Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Galactose; Humans; Imidazoles; Imidazolidines; Lens, Crystalline; Photography; Random Allocation; Rats; Rats, Inbred Strains | 1991 |
Relationship between aldose reductase inhibiting activity and anti-cataract action of various non-steroidal anti-inflammatory drugs.
Topics: Aldehyde Reductase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cataract; Flurbiprofen; Galactose; Lens, Crystalline; Naproxen; Ophthalmic Solutions; Piroxicam; Rats; Sulindac | 1991 |
Naproxen: an aldose reductase inhibitor and potential anti-cataract agent.
Topics: Aldehyde Reductase; Animals; Cataract; Dogs; Galactitol; Galactose; Goats; Humans; In Vitro Techniques; Lens, Crystalline; Naproxen; Ophthalmic Solutions; Rats; Taurine | 1991 |
Evaluation of lens epithelial cell differentiation by quantitation of MP26 mRNA relative to gamma-crystallin mRNA in initiation of galactose cataracts in the rat.
Topics: Animals; Aquaporins; Blotting, Northern; Cataract; Cell Differentiation; Crystallins; Eye Proteins; Female; Galactose; Lens, Crystalline; Membrane Glycoproteins; Rats; Rats, Inbred Strains; RNA, Messenger; Time Factors | 1991 |
[Measurement of the erythrocyte galactokinase activity in patients with presenile and senile idiopathic cataract. Preliminary study].
Topics: Adult; Age Factors; Aged; Cataract; Erythrocytes; Galactokinase; Galactose; Humans; Middle Aged | 1990 |
Elemental distribution in frozen-hydrated rat lenses with galactose cataract.
Topics: Animals; Calcium; Cataract; Electron Probe Microanalysis; Female; Galactose; Lens, Crystalline; Potassium; Rats; Rats, Inbred Strains; Sodium; Sulfur | 1990 |
Management of aldose reductase mRNA abundance in rat lens undergoing reversal of galactose induced cataracts. A model for gene response to changes in the environment.
Topics: Aldehyde Reductase; Animals; Cataract; DNA; Galactose; Genes; Lens, Crystalline; Nucleic Acid Hybridization; Rats; RNA, Messenger; Sugar Alcohol Dehydrogenases | 1990 |
[Preventional and therapeutic effects of aldose reductase inhibitor FR74366 on rat galactose cataract].
Topics: Aldehyde Reductase; Animals; Cataract; Galactose; Quinazolines; Rats; Sugar Alcohol Dehydrogenases | 1990 |
Plasma polyol levels in patients with cataract.
Topics: Carbohydrate Epimerases; Cataract; Child, Preschool; Galactitol; Galactokinase; Galactose; Heterozygote; Homozygote; Humans; Infant; Infant, Newborn; Mutation; Polymers; Sorbitol; UDPglucose 4-Epimerase; UTP-Hexose-1-Phosphate Uridylyltransferase | 1990 |
Effects of novel hydantoin derivatives with aldose reductase inhibiting activity on galactose-induced cataract in rats.
Topics: Aldehyde Reductase; Animals; Benzofurans; Cataract; Cattle; Enzyme Inhibitors; Galactose; Hydantoins; Lens, Crystalline; Male; Rats; Rats, Inbred Strains | 1990 |
Reversal of the limited proteolysis of MP26 during the reversal and prevention of the galactose cataract in rat lenses.
Topics: Aging; Animals; Aquaporins; Cataract; Diet; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Female; Galactose; Lens Cortex, Crystalline; Lens Nucleus, Crystalline; Lens, Crystalline; Membrane Glycoproteins; Peptide Hydrolases; Rats; Rats, Inbred Strains | 1990 |
Metabolic studies of galactosemic cataract.
Topics: Animals; Cataract; Galactitol; Galactose; Galactosemias; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Phosphorus; Rats; Rats, Inbred Strains | 1990 |
Calpain II in two in vivo models of sugar cataract.
Topics: Animals; Antigens; Calpain; Cataract; Crystallins; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Disease Models, Animal; Galactose; Lens, Crystalline; Rats; Rats, Inbred Strains | 1990 |
Abnormal redox status without increased lipid peroxidation in sugar cataract.
Topics: Animals; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cataract; Diabetic Retinopathy; Galactitol; Galactose; Glutathione; Lens, Crystalline; Lipid Peroxidation; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1990 |
Ibuprofen, a putative anti-cataract drug, protects the lens against cyanate and galactose.
Topics: Animals; Cataract; Cattle; Crystallins; Cyanates; Galactose; Ibuprofen; Lens, Crystalline; Male; Rats; Temperature | 1990 |
Allopurinol promotes and butylated hydroxy toluene prevents sugar-induced cataractogenesis.
Topics: Allopurinol; Animals; Butylated Hydroxytoluene; Cataract; Diabetes Mellitus, Experimental; Diet; Galactose; Galactosemias; Lipid Peroxidation; Male; Rats; Rats, Inbred Strains | 1990 |
The role of lens epithelium in sugar cataract formation.
Topics: Animals; Cataract; Dietary Carbohydrates; Epithelium; Galactose; Lens, Crystalline; Male; Rats; Rats, Inbred Strains | 1990 |
Differential effects of galactose-induced cataractogenesis on the soluble crystallins of rat lens.
Topics: Animals; Cataract; Crystallins; Dietary Carbohydrates; Electrophoresis, Gel, Two-Dimensional; Galactose; Male; Rats; Rats, Inbred Strains; Solubility | 1990 |
Changes of lens protein particles during development and reversal of galactose cataracts. Study by laser scattering spectroscopy.
Topics: Animals; Cataract; Crystallins; Galactose; Lens, Crystalline; Light; Male; Particle Size; Rats; Rats, Inbred Strains; Scattering, Radiation | 1990 |
[The diagnostic value of the Davidson fixation method on the toxicological evaluation of eye lesions--histopathological findings of cataract formation following galactose diet intake in rats].
Topics: Animals; Cataract; Female; Fixatives; Galactose; Male; Microtomy; Rats; Rats, Inbred F344; Staining and Labeling | 1986 |
Relative abundance of aldose reductase mRNA in rat lens undergoing development of osmotic cataracts.
Topics: Aldehyde Reductase; Animals; Blotting, Northern; Cataract; DNA; Epithelium; Galactose; Immunoblotting; Lens Capsule, Crystalline; Lens Cortex, Crystalline; Lens, Crystalline; Nucleic Acid Hybridization; Osmotic Pressure; Rats; RNA; RNA, Antisense; RNA, Messenger; Sugar Alcohol Dehydrogenases | 1989 |
Elemental and structural studies of the rat galactose cataract.
Topics: Animals; Cataract; Diet; Electrolytes; Electron Probe Microanalysis; Female; Galactose; Lens, Crystalline; Rats; Rats, Inbred Strains | 1989 |
The effects of 5% and 25% galactose diets on lens polyols, glutathione and protein glycation in male and female pigs.
Topics: Animals; Cataract; Chromatography, Gas; Chromatography, High Pressure Liquid; Diet; Female; Galactitol; Galactose; Glutathione; Inositol; Lens, Crystalline; Lysine; Male; Sex Factors; Sorbitol; Sugar Alcohols; Swine; Time Factors | 1989 |
Cataract formation in patients with lactose and galactose disorders.
Topics: beta-Galactosidase; Carbohydrate Metabolism, Inborn Errors; Cataract; Galactokinase; Galactose; Humans; Lactose; Middle Aged; UTP-Hexose-1-Phosphate Uridylyltransferase | 1989 |
[Movement of regenerated lens epithelial cells in 50% galactose cataract and an aldose reductase inhibitor].
Topics: Aldehyde Reductase; Animals; Cataract; Cell Movement; Epithelium; Galactose; Lens, Crystalline; Male; Rats; Rats, Inbred Strains; Regeneration; Sugar Alcohol Dehydrogenases | 1989 |
Aqueous/vitreous tonicity in "sugar' cataracts.
Topics: Animals; Aqueous Humor; Cataract; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Female; Galactose; Humans; Male; Osmotic Pressure; Rabbits; Rats; Rats, Inbred Strains; Streptozocin; Vitreous Body | 1989 |
Idiopathic presenile cataract formation and galactosaemia.
Topics: Adult; Cataract; Cataract Extraction; Erythrocytes; Female; Galactokinase; Galactose; Galactosemias; Humans; Male; Middle Aged; Nucleotidyltransferases; UTP-Hexose-1-Phosphate Uridylyltransferase | 1989 |
Aldose reductase inhibitors and prevention of galactose cataracts in rats.
Topics: Aldehyde Reductase; Animals; Cataract; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Sugar Alcohol Dehydrogenases; Time Factors | 1989 |
Prefeeding of aldose reductase inhibitor and galactose cataractogenesis.
Topics: Aldehyde Reductase; Animals; Cataract; Diet; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Sugar Alcohol Dehydrogenases | 1989 |
Dietary myo-inositol effect on sugar cataractogenesis.
Topics: Animals; Carbohydrates; Cataract; Chromatography, Gas; Diabetes Mellitus, Experimental; Diet; Galactose; Inositol; Lens, Crystalline; Male; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains | 1989 |
Nuclear magnetic resonance microscopic ocular imaging for the detection of early-stage cataract.
Topics: Animals; Cataract; Galactose; Lens, Crystalline; Magnetic Resonance Imaging; Rabbits; Time Factors | 1989 |
Galactose-induced cataract in rat: Raman detection of sulfhydryl decrease and water increase along an equatorial diameter.
Topics: Animals; Body Water; Cataract; Crystallins; Galactose; Lens, Crystalline; Protein Conformation; Rats; Rats, Inbred Strains; Spectrum Analysis, Raman; Sulfhydryl Compounds; Tyrosine | 1989 |
[A study on the metabolism of galactose cataract using a 31P-NMR spectroscopy].
Topics: Animals; Cataract; Energy Metabolism; Galactose; Kinetics; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Phosphorus; Rats; Rats, Inbred Strains | 1989 |
Inhibition of phase separation by reagents that prevent X-irradiation cataract in vivo.
Topics: Amifostine; Animals; Cataract; Cattle; Galactose; Lens, Crystalline; Organothiophosphorus Compounds; Radiation-Sensitizing Agents; Temperature | 1987 |
The accumulation of myoinositol and rubidium ions in galactose-exposed rat lens.
Topics: Aldehyde Reductase; Animals; Cataract; Galactose; Hypertonic Solutions; Imidazoles; Imidazolidines; Inositol; Lens, Crystalline; Male; Radioisotopes; Rats; Rubidium; Sodium-Potassium-Exchanging ATPase | 1986 |
Rat lens prostaglandin biosynthesis during galactose-induced cataractogenesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cataract; Cyclic AMP; Dinoprost; Dinoprostone; Galactose; Lens, Crystalline; Male; Microsomes; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostaglandins H; Rats; Rats, Inbred Strains | 1986 |
Effect of prolactin on galactose cataractogenesis.
Topics: Animals; Cataract; Female; Galactitol; Galactose; Lens, Crystalline; Prolactin; Rats; Sodium-Potassium-Exchanging ATPase | 1987 |
Prevention of basement membrane thickening in retinal capillaries by a novel inhibitor of aldose reductase, tolrestat.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Cataract; Diabetic Retinopathy; Galactose; Male; Microscopy, Electron; Naphthalenes; Rats; Rats, Inbred Strains; Retinal Vessels; Sugar Alcohol Dehydrogenases | 1986 |
Hyperglycemia as a cause of diabetic retinopathy.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Cataract; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dogs; Galactose; Galactosemias; Glycated Hemoglobin; Hexoses; Humans; Hyperglycemia; Rats; Retinal Vessels | 1986 |
[An aspect of cell level changes in the sugar-induced cataractous lens].
Topics: Aldehyde Reductase; Animals; Cataract; Cell Count; Cell Division; Cells, Cultured; Epithelium; Galactose; Hexokinase; Lactates; Lactic Acid; Lens Capsule, Crystalline; Male; Rats; Rats, Inbred Strains | 1986 |
[Experimental studies on the development and reversal of galactose cataracts].
Topics: Animals; Cataract; Female; Galactose; Lens, Crystalline; Male; Rats | 1987 |
[Effect of zinc on experimental galactose cataract].
Topics: Animals; Cataract; Female; Galactose; Male; Rats; Zinc | 1987 |
[Cytological aspects of sugar-induced cataract formation].
Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Galactose; Imidazoles; Imidazolidines; Male; Rats; Rats, Inbred Strains; Vitamin E | 1988 |
Strain difference in galactokinase level and susceptibility to the teratogenic effect of dietary galactose in mice: I. Teratogenic and embryopathic effect.
Topics: Animals; Cataract; Diet; Galactokinase; Galactose; Mice; Mice, Inbred A; Mice, Inbred C57BL; Species Specificity; Teratogens | 1988 |
Prevention of sugar-induced cataractogenesis in rats by butylated hydroxytoluene.
Topics: Animals; Butylated Hydroxytoluene; Cataract; Galactitol; Galactose; Glutathione; Lens, Crystalline; Male; Organ Size; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1988 |
Effect of sodium iodate injection on the development of galactose cataract in the rat.
Topics: Animals; Cataract; Diet; Female; Galactitol; Galactose; Injections; Iodates; Iodine; Lens, Crystalline; Male; Microscopy, Electron; Potassium; Rats; Rats, Inbred Strains; Retina; Sodium | 1988 |
Histopathologic observations on galactose-induced cataract in rats.
Topics: Animals; Cataract; Galactose; Male; Rats; Rats, Inbred Strains | 1988 |
[Proliferative ability of lens epithelial cells in cataracts in 50% galactose chow-fed rats].
Topics: Animals; Cataract; Cell Division; DNA; Epithelium; Galactose; Lens, Crystalline; Male; Rats; Rats, Inbred Strains | 1988 |
Survival of fiber cells and fiber-cell messenger RNA in lens of rats maintained on a 50% galactose diet for 45 days.
Topics: Animals; Cataract; Cell Survival; Crystallins; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Galactose; Lens, Crystalline; Molecular Weight; Rats; RNA, Messenger; Time Factors | 1987 |
MP26 messenger RNA sequences in normal and cataractous lens. A molecular probe for abundance and distribution of a fiber cell-specific gene product.
Topics: Animals; Aquaporins; Cataract; Eye Proteins; Female; Galactose; Lens, Crystalline; Membrane Glycoproteins; Nucleic Acid Hybridization; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Messenger | 1988 |
[A rat experimental posterior subcapsular cataract model resembling human diabetic cataract].
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Disease Models, Animal; Galactose; Male; Rats; Rats, Inbred Strains | 1988 |
[Morphological study of diet-reversal in rat galactose cataract].
Topics: Animals; Cataract; Dietary Carbohydrates; Galactose; Rats; Rats, Inbred Strains | 1988 |
The major metabolite of bendazac inhibits the glycosylation of soluble lens proteins: a possible mechanism for a delay in cataractogenesis.
Topics: Animals; Cataract; Cattle; Crystallins; Galactose; Glucosephosphates; Glycosylation; In Vitro Techniques; Indazoles; Protein Binding; Pyrazoles | 1988 |
Limited proteolysis of MP26 in lens fiber plasma membranes of the galactose-induced cataract in the rat.
Topics: Animals; Aquaporins; Cataract; Cell Membrane; Eye Proteins; Female; Galactose; Lens, Crystalline; Membrane Glycoproteins; Peptide Hydrolases; Rats; Rats, Inbred Strains | 1986 |
Galactose tolerance in patients with atopic cataracts.
Topics: Adolescent; Adult; Cataract; Child; Eczema; Galactose; Galactosemias; Humans; Lens, Crystalline | 1987 |
Response of the lens of the galactose-fed rat to YAG laser-induced injury.
Topics: Animals; Cataract; Epithelium; Female; Galactose; Lasers; Lens, Crystalline; Mitosis; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Galactose metabolism in male and female rats. II. Eye-ball differences.
Topics: Animals; Aqueous Humor; Cataract; Dietary Carbohydrates; Female; Galactitol; Galactose; Galactosemias; Glucose; Lactose; Lens, Crystalline; Male; Rats | 1986 |
Quantitative microlocalization of diffusible ions in normal and galactose cataractous rat lens by secondary ion mass spectrometry.
Topics: Animals; Cataract; Galactose; Lens, Crystalline; Mass Spectrometry; Microscopy, Electron, Scanning; Rats | 1986 |
Acid phosphatase II. Cytochemical localization in lenses of normal and galactose-fed rats.
Topics: Acid Phosphatase; Aldehyde Reductase; Animals; Cataract; Female; Galactose; Histocytochemistry; Imidazoles; Imidazolidines; Lens, Crystalline; Lysosomes; Microscopy, Electron; Rats; Rats, Inbred Strains | 1985 |
Changes of some biochemical parameters of the lens in galactose-treated weaned rats with and without vitamin E therapy.
Topics: Aldehyde Reductase; Animals; Cataract; Crystallins; Galactose; Galactosemias; Lens, Crystalline; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vitamin E | 1985 |
Reversal of stage-I sugar cataract by Sorbinil, an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Cataract; Diet; Female; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases | 1985 |
Synergism of sorbinil and normal diet on reversal of stage-II sugar cataract.
Topics: Aldehyde Reductase; Animals; Cataract; Combined Modality Therapy; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases | 1985 |
[Prevention and reversal of rat galactosemic cataract with aldose reductase inhibitor--immunohistochemical study].
Topics: Aldehyde Reductase; Animals; Cataract; Galactose; Rats; Rats, Inbred Strains; Sorbitol; Sugar Alcohol Dehydrogenases | 1985 |
Cataracts in patients heterozygous for galactokinase deficiency.
Topics: Adolescent; Adult; Aged; Cataract; Diet; Female; Galactokinase; Galactose; Heterozygote; Humans; Male; Middle Aged | 1986 |
Modelling cortical cataractogenesis VII: Effects of vitamin E treatment on galactose-induced cataracts.
Topics: Animals; Cataract; Galactitol; Galactose; In Vitro Techniques; Lens, Crystalline; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains; Vitamin E | 1985 |
Prevention of cataract development in severely galactosemic rats by the aldose reductase inhibitor, tolrestat.
Topics: Animals; Cataract; Dose-Response Relationship, Drug; Galactitol; Galactose; Galactosemias; Humans; Lens, Crystalline; Male; Naphthalenes; Rats | 1985 |
Ultrastructural cytochemistry: effect of Sorbinil on arylsulfatases in cataractous lenses.
Topics: Animals; Arylsulfatases; Cataract; Epithelium; Female; Galactose; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Lysosomes; Microscopy, Electron; Rats; Rats, Inbred Strains; Sulfatases; Wound Healing | 1985 |
Direct and maternal aspects of the risk of cataract with partial disorders of galactose metabolism.
Topics: Adolescent; Adult; Carbohydrate Metabolism, Inborn Errors; Cataract; Female; Galactokinase; Galactose; Heterozygote; Humans; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Pregnancy; Risk; UTP-Hexose-1-Phosphate Uridylyltransferase | 1985 |
Interaction of galactose and dietary protein deficiency on rat lens.
Topics: Animals; Cataract; Galactose; Male; Protein Deficiency; Rats; Rats, Inbred Strains | 1985 |
A temporal and spatial study of the synthesis and degradation of water-soluble and insoluble proteins in galactosemic rat lenses.
Topics: Animals; Autoradiography; Cataract; Crystallins; Electrophoresis, Polyacrylamide Gel; Female; Galactose; Galactosemias; Methionine; Rats; Rats, Inbred Strains; Solubility; Time Factors | 1985 |
Further observations on the effect of galactose on the development of X-ray-induced cataract in mice.
Topics: Animals; Cataract; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Galactose; Lens, Crystalline; Mice; Microscopy, Electron; Time Factors | 1985 |
Amniotic-cell galactokinase activity: stimulation by galactose.
Topics: Amniocentesis; Amniotic Fluid; Cataract; Cells, Cultured; Female; Fetal Diseases; Galactose; Humans; Metabolism, Inborn Errors; Phosphotransferases; Pregnancy; Prenatal Diagnosis; Stimulation, Chemical | 1973 |
Maternal enzymes of galactose metabolism and the "inexplicable" infantile cataract.
Topics: Adolescent; Adult; Carbohydrate Metabolism, Inborn Errors; Cataract; Child; Child, Preschool; Erythrocytes; Female; Galactose; Humans; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Nucleotidyltransferases; Phosphotransferases; Pregnancy; Pregnancy Complications | 1974 |
Letter: Infantile cataract and galactose metabolism.
Topics: Cataract; Female; Galactose; Humans; Infant, Newborn; Maternal-Fetal Exchange; Nucleotidyltransferases; Phosphotransferases; Pregnancy | 1974 |
Deficiency of erythrocyte galactokinase in a patient with galactose diabetes.
Topics: Adolescent; Adult; Carbohydrate Metabolism, Inborn Errors; Cataract; Child; Diabetes Mellitus; Galactose; Humans; Male; Middle Aged; Neurofibromatosis 1; Phosphotransferases | 1965 |
[Variation of some enzymatic activities of the rat crystalline lens in experimental galactose cataract (lactate dehydrogenase, leucine aminopeptidase, phosphoglucose isomerase].
Topics: Animals; Cataract; Galactose; Glucose-6-Phosphate Isomerase; L-Lactate Dehydrogenase; Lens, Crystalline; Leucyl Aminopeptidase; Male; Rats | 1968 |
Variations in ATPase activity in the development of experimental cataracts.
Topics: Adenosine Triphosphatases; Animals; Cataract; Epithelium; Galactose; Lenses; Magnesium; Male; Potassium; Rats; Sodium | 1971 |
Polyol accumulation in galactosemic and diabetic rats: control by an aldose reductase inhibitor.
Topics: Acetates; Administration, Oral; Alcohol Oxidoreductases; Animals; Cataract; Culture Techniques; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Fructose; Galactose; Galactosemias; Glucose; Isoquinolines; Lens, Crystalline; Rats; Sciatic Nerve; Sorbitol; Streptozocin; Sugar Alcohols | 1973 |
Lipids in tissues of the eye. V. Phospholipid metabolism in normal and cataractous lens.
Topics: Aging; Albumins; Alcohols; Alloxan; Animals; Cataract; Cattle; Cytosine Nucleotides; Diabetes Mellitus, Experimental; Fructose; Galactose; Glucose; Hydrogen-Ion Concentration; Inositol; Lens, Crystalline; Lipid Metabolism; Male; Microsomes; Osmolar Concentration; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Phosphorus; Phosphorus Isotopes; Rats; Stimulation, Chemical; Surface-Active Agents; Tritium | 1971 |
Some inferences from galactokinase deficiency.
Topics: Carbohydrate Metabolism, Inborn Errors; Cataract; Dietary Carbohydrates; Diseases in Twins; Female; Galactose; Humans; Infant; Phosphotransferases | 1974 |
Galactokinase deficiency in twins: clinical and biochemical studies.
Topics: Carbohydrate Metabolism, Inborn Errors; Carbon Radioisotopes; Cataract; Diet Therapy; Dietary Carbohydrates; Diseases in Twins; Erythrocytes; Female; Galactose; Galactosemias; Humans; Infant; Infant Food; Nucleotidyltransferases; Oxidative Phosphorylation; Phosphotransferases | 1974 |
A fluorescent spot test for the detection of galactokinase deficiency.
Topics: Adult; Cataract; Drug Stability; Evaluation Studies as Topic; Fluorides; Galactose; Galactosemias; Humans; Infant, Newborn; Mass Screening; Methods; Phosphotransferases; Spectrometry, Fluorescence; Time Factors | 1974 |
[The family of a patient with galactokinase-defect 2nd communication (author's transl)].
Topics: Adult; Age Factors; Alleles; Cataract; Child; Female; Galactose; Galactosemias; Hemoglobins; Heterozygote; Homozygote; Humans; Infant, Newborn; Male; Metabolism, Inborn Errors; Pedigree; Phosphotransferases; Pregnancy; Twins | 1974 |
Human cataract and galactose metabolism.
Topics: Adult; Aged; Blood Glucose; Carbon Radioisotopes; Cataract; Erythrocytes; Female; Flavin-Adenine Dinucleotide; Galactose; Glucosephosphates; Glutathione Reductase; Glycosuria; Humans; Male; Middle Aged; Nucleotidyltransferases; Phosphotransferases; Riboflavin; Riboflavin Deficiency; Uracil Nucleotides | 1974 |
Letter: Galactokinase deficiency in twins.
Topics: Adult; Cataract; Child, Preschool; Diseases in Twins; Female; Galactitol; Galactose; Humans; Phosphotransferases | 1974 |
The absence of cataracts in mice with congenital hyperglycemia.
Topics: Alcohol Oxidoreductases; Animals; Cataract; Diabetes Mellitus; Diet; Fructose; Galactitol; Galactose; Glucose; Glucosephosphate Dehydrogenase; Hexokinase; Hyperglycemia; Inositol; Lens, Crystalline; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phosphogluconate Dehydrogenase | 1974 |
The nutritional teamwork approach: prevention and regression of cataracts in rats.
Topics: Animals; Cataract; Diet Therapy; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Galactose; Male; Nutritional Requirements; Rats | 1974 |
[Investigations on the latency period of galactose cataract of rats. Influence of x-irradiation and time of diet application with animals of different age (author's transl)].
Topics: Age Factors; Animals; Cataract; Dietary Carbohydrates; Disease Models, Animal; Galactose; Lens, Crystalline; Photography; Radiation Effects; Rats; Time Factors | 1974 |
Species variation in galactokinase activity of erythrocytes, lens and liver.
Topics: Animals; Cataract; Erythrocytes; Galactose; Glucose; Humans; Lens, Crystalline; Liver; Methemoglobin; Oxidation-Reduction; Phosphotransferases; Rabbits; Rats; Species Specificity | 1972 |
Galactokinase-deficiency cataracts in identical twins.
Topics: Cataract; Diseases in Twins; Erythrocytes; Female; Galactose; Galactosemias; Humans; Infant; Metabolism, Inborn Errors; Phosphotransferases | 1972 |
Galactitol accumulation and irreversible lens opacities in galactosemic rats.
Topics: Animals; Cataract; Dietary Carbohydrates; Galactitol; Galactose; Galactosemias; Lens, Crystalline; Male; Rats; Remission, Spontaneous; Sugar Alcohols; Time Factors | 1973 |
[Induction of enzymes transforming galactose to glucose in animal liver due to galactose].
Topics: Adenine; Animals; Carbohydrate Epimerases; Carbon Isotopes; Cataract; Dactinomycin; Dietary Carbohydrates; Enzyme Induction; Galactose; Glucose; Liver; Male; Nucleotidyltransferases; Phosphotransferases; Rats; RNA; Seasons | 1973 |
Galactokinase deficiency as a cause of cataracts.
Topics: Adolescent; Adult; Age Factors; Cataract; Child; Child, Preschool; Diet Therapy; Dietary Carbohydrates; Erythrocytes; Galactose; Galactosemias; Heterozygote; Humans; Infant; Infant, Newborn; Middle Aged; Nucleotidyltransferases; Phosphotransferases | 1973 |
The lens, cataracts, and galactosemia.
Topics: Cataract; Diet Therapy; Erythrocytes; Galactose; Galactosemias; Heterozygote; Humans; Infant; Infant, Newborn; Lens, Crystalline; Nucleotidyltransferases; Phosphotransferases | 1973 |
Letter: Negative urine sugars in galactosemia.
Topics: Adolescent; Cataract; Galactose; Galactosemias; Hexosephosphates; Humans; Infant; Nucleotidyltransferases; Uracil Nucleotides | 1974 |
The effects of xylose on the isolated lens.
Topics: Acetates; Alcohol Oxidoreductases; Animals; Cataract; Culture Media; Culture Techniques; Galactose; Glucose; Isoquinolines; Lens, Crystalline; Osmosis; Rats; Sugar Alcohols; Time Factors; Xylose | 1974 |
[Pathologic lens changes in experimental animals following continuous administration of high doses of Desferal].
Topics: Animals; Cataract; Cats; Deferoxamine; Dogs; Edetic Acid; Female; Galactose; Lens, Crystalline; Male; Rats | 1967 |
Cataracts and galactokinase deficiency.
Topics: Adult; Carbohydrate Metabolism, Inborn Errors; Cataract; Galactose; Humans; Infant; Phosphotransferases | 1972 |
Galactokinase deficiency: clinical and biochemical findings in a new kindred.
Topics: Adult; Carbohydrate Metabolism, Inborn Errors; Cataract; Erythrocytes; Female; Fibroblasts; Galactose; Humans; Male; Neurologic Manifestations; Nucleotidyltransferases; Pedigree; Phosphotransferases; Seizures; Skin | 1972 |
Galactose cataract in riboflavin deficient rats.
Topics: Animals; Cataract; Diet; Erythrocytes; Eye; Eye Proteins; Galactose; Glutathione; Glutathione Reductase; Ointments; Rats; Rats, Inbred Strains; Riboflavin; Riboflavin Deficiency; Time Factors | 1972 |
Dose dependence of galactose cataract in the rat.
Topics: Adenine Nucleotides; Animals; Cataract; Ethanol; Female; Galactose; Lens, Crystalline; Ophthalmoscopy; Rats; Time Factors | 1972 |
Hereditary galactokinase deficiency.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Carbohydrates; Cataract; Diet; Erythrocytes; Galactose; Glycosuria; Hexosamines; Humans; Hyperbilirubinemia, Hereditary; Infant; Male; Milk; Phosphotransferases | 1971 |
Properties of a ribonuclease inhibitor from bovine lens.
Topics: Animals; Cataract; Cattle; Chromatography, DEAE-Cellulose; Diet; Galactose; Humans; Lens, Crystalline; Male; Mercuribenzoates; Papain; Pronase; Proteins; Rats; Ribonucleases; Sulfhydryl Reagents; Trypsin; Water | 1971 |
Experimental cataracts by addition of sublimal factors.
Topics: Animals; Anterior Chamber; Cataract; Diabetes Mellitus, Experimental; Galactose; Lens, Crystalline; Naphthalenes; Oxyphenbutazone; Pilocarpine; Punctures; Rabbits; Radiation Effects; Rats | 1971 |
[An unusual form of galactose metabolism disorder].
Topics: Cataract; Child, Preschool; Diagnosis, Differential; Female; Galactose; Galactosemias; Hexosephosphates; Humans; Metabolism, Inborn Errors; Phosphorus; Phosphotransferases | 1971 |
Formation of experimental cataracts and urinary amino acids.
Topics: Animals; Cataract; Dietary Carbohydrates; Female; Galactose; Rats; Renal Aminoacidurias; Taurine; Xylose | 1967 |
[Morphological and histochemical studies of the galactose cataract of the albino rat].
Topics: Animals; Carbohydrate Metabolism, Inborn Errors; Cataract; Galactose; Humans; Infant, Newborn; Infant, Newborn, Diseases; Microscopy; Oxidoreductases; Proteins; Rats | 1965 |
[Effect of orotic acid on the experimental galactose cataract with histochemical results of the investigations].
Topics: Animals; Cataract; Galactose; Humans; Nucleotidyltransferases; Orotic Acid; Rats | 1965 |
Studies on the promoting factors of galactose and lactose metabolism in the whey. II. The effect of the promoting factors on the galactose and lactose metabolism upon the activity of D-glucose-6-phosphate. NADP oxidoreductase and the electrolytes included
Topics: Animals; Calcium; Cataract; Dietary Carbohydrates; Electrolytes; Erythrocytes; Eye; Galactose; Glucosephosphate Dehydrogenase; Lactose; Milk; Organ Size; Potassium; Rats; Sodium; Water | 1969 |
Studies on the promoting factors of galactose and lactose metabolism in the whey. I. The effects of the promoting factors of the galactose and lactose metabolism in the activity of the Leloir enzyme system in the cataract rat.
Topics: Animals; Cataract; Dietary Carbohydrates; Eye; Galactose; Isomerases; Lactose; Milk; Phosphotransferases; Rats | 1969 |
Studies on the promoting factors of galactose and lactose metabolism in the whey. 3. Concerning substances in whey that inhibit cataract developed in rats on hypergalactose and hyperlactose diets.
Topics: Animals; Cataract; Chromatography, Gas; Dairy Products; Dietary Carbohydrates; Fatty Acids; Galactose; Lactose; Rats | 1971 |
[Relation between galactose and the crystalline lens].
Topics: Cataract; Galactose; Galactosemias; Humans; Lens, Crystalline; Nucleotidyltransferases; Phosphates; Phosphotransferases | 1969 |
Changes in the levels of free amino acids and myo-inositol in the galactose-exposed lens.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Carbohydrates; Cataract; Culture Techniques; Diet; Female; Galactose; Glutarates; Inositol; Lens, Crystalline; Osmotic Pressure; Rabbits; Rats | 1969 |
[From genes to enzymes: galactosemia].
Topics: Blood Glucose; Cataract; Diet Therapy; Galactose; Galactosemias; Humans; Kidney Diseases; Liver Cirrhosis; Liver Function Tests; Proteinuria | 1969 |
[Results of the influence of ionizing radiation on the lens with facial reference to the interpretation of their metabolism using factor analysis].
Topics: Age Factors; Animals; Cataract; Cattle; Factor Analysis, Statistical; Fructose-Bisphosphate Aldolase; Galactose; Guinea Pigs; Lens, Crystalline; Malate Dehydrogenase; Organ Size; Radiation Effects; Rats; Time Factors | 1969 |
[Additional development of cataract following corticosteroid administration in rats fed with galactose].
Topics: Animal Feed; Animals; Betamethasone; Cataract; Galactose; Lens, Crystalline; Rats | 1969 |
[Polysaccharid content of the rat eye lens following galactose feeding].
Topics: Animal Feed; Animals; Cataract; Galactose; Insulin; Lens, Crystalline; Polysaccharides; Rats | 1969 |
Light scattering in lenses with experimental cataract.
Topics: Animals; Biophysical Phenomena; Biophysics; Cataract; Crystallins; Galactose; Lens, Crystalline; Light; Male; Microradiography; Radiation Injuries, Experimental; Rats; Spectrophotometry | 1969 |
Biophysical studies on normal and cataractous rat lenses.
Topics: Absorptiometry, Photon; Age Factors; Animals; Cataract; Diet; Eye Proteins; Freeze Drying; Galactose; Lens, Crystalline; Male; Microradiography; Nitrogen; Rats | 1969 |
[Carbohydrate metabolism anomalies; galactose metabolism].
Topics: Carbohydrate Metabolism, Inborn Errors; Cataract; Clinical Enzyme Tests; Galactose; Galactosidases; Humans; Liver Cirrhosis; Malabsorption Syndromes | 1969 |
Increased susceptibility of riboflavin deficient rats to galactose cataract.
Topics: Animals; Cataract; Dietary Carbohydrates; Erythrocytes; Eye Proteins; Flavin-Adenine Dinucleotide; Galactose; Glutathione Reductase; Lens, Crystalline; Rats; Riboflavin Deficiency; Sulfhydryl Compounds | 1970 |
Dulcitol and water concentrations in galactose cataracts of the hamster.
Topics: Animals; Body Weight; Cataract; Chromatography, Gas; Chromatography, Paper; Cricetinae; Galactose; Lens, Crystalline | 1970 |
The isolation and partial structural characterization of some ocular gangliosides.
Topics: Amino Alcohols; Animals; Cataract; Cattle; Chromatography, Gas; Eye; Fatty Acids; Galactose; Gangliosides; Glucose; Humans; Iris; Lens, Crystalline; Neuraminic Acids | 1970 |
Cataracts produced in rats by yogurt.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cataract; Dairy Products; Food-Processing Industry; Galactose; Lens, Crystalline; Rats | 1970 |
[Observations concerning congenital and postnatal early cataract].
Topics: Cataract; Galactose; Humans; Infant, Newborn; Infant, Premature, Diseases | 1970 |
Changes in lens fatty acid composition during galactose cataract formation.
Topics: Animal Feed; Animals; Calorimetry; Cataract; Chemical Phenomena; Chemistry; Cholesterol; Chromatography; Dietary Fats; Fatty Acids; Galactose; Lens, Crystalline; Lipids; Rats; Sucrose; Time Factors | 1970 |
Lens regeneration after mature galactose cataract formation.
Topics: Animals; Cataract; Dietary Carbohydrates; Galactose; Lens, Crystalline; Male; Rats; Regeneration | 1970 |
Soluble lens proteins in rats on different sugar diets.
Topics: Animals; Cataract; Chromatography, Gel; Crystallins; Dietary Carbohydrates; Electrophoresis; Galactose; Immunoelectrophoresis; Lactose; Molecular Weight; Rats; Solubility; Sucrose; Ultracentrifugation | 1970 |
[Galactokinase defect in a newborn infant].
Topics: Carbon Isotopes; Cataract; Chromatography, Paper; Chromatography, Thin Layer; Diet Therapy; Erythrocytes; Ethnicity; Female; Galactose; Glucokinase; Humans; Infant, Newborn; Infant, Newborn, Diseases; Metabolism, Inborn Errors; Oxidation-Reduction; RNA Nucleotidyltransferases | 1970 |
Yogurt-induced cataracts: comments on their significance to man.
Topics: Cataract; Dairy Products; Dietary Fats; Galactose; Galactosemias; Humans | 1970 |
[Galactosemia as based on the records of Department I of Pediatrics of the Silesian Medical Academy].
Topics: Body Weight; Cataract; Child, Preschool; Female; Galactose; Galactosemias; Hepatomegaly; Heterozygote; Homozygote; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Pedigree; Splenomegaly | 1971 |
Cataracts, galactosuria and hypergalactosemia due to galactokinase deficiency in a child. Studies of a kindred.
Topics: Adult; Aged; Carbohydrate Metabolism, Inborn Errors; Cataract; Child; Erythrocytes; Female; Galactose; Galactosemias; Genes, Recessive; Humans; Male; Pedigree; Phosphotransferases; United States | 1971 |
[Galactose metabolism disturbance in juvenile cataracts].
Topics: Adolescent; Adult; Cataract; Child; Female; Galactose; Galactosemias; Humans; Lens, Crystalline; Male; Middle Aged | 1967 |
The transport of 14C-alpha-aminoisobutyric acid in galactose cataracts in rats and rabbit lenses incubated in high galactose media.
Topics: Aminoisobutyric Acids; Animals; Aqueous Humor; Biological Transport; Carbon Isotopes; Cataract; Galactose; Galactosemias; Glucose; In Vitro Techniques; Lens, Crystalline; Rabbits; Rats | 1968 |
Changes in cation permeability in the galactose--exposed rabbit lens.
Topics: Animals; Biological Transport; Cataract; Chlorides; Galactose; Lens, Crystalline; Osmosis; Potassium; Rabbits; Radioisotopes; Rubidium; Sodium | 1968 |
Cataractogenic effect of corticosteroids on animals.
Topics: Animals; Cataract; Chickens; Dinitrophenols; Drug Synergism; Galactose; Phenylbutazone; Prednisolone; Prednisone; Rabbits; Rats; Triparanol; Xylose | 1968 |
[Effect of glucose and galactose on protein synthesis in the lens].
Topics: Animals; Cataract; Crystallins; Galactose; Glucose; Guinea Pigs; Lens, Crystalline; Rats; Sorbitol | 1968 |
Lens epithelium proliferation in sugar cataracts.
Topics: Alloxan; Animals; Carbohydrates; Cataract; Diabetes Mellitus, Experimental; Diet; Epithelial Cells; Epithelium; Galactose; Humans; Lens, Crystalline; Mitosis; Rats; Xylose | 1968 |
[Galactose cataract of young rats following whole-body irradiation].
Topics: Age Factors; Animals; Cataract; Galactose; Radiation Injuries, Experimental; Rats; Time Factors | 1968 |
[Experimental analytical contribution to the study of the pathogenesis of cataract. VI. Comparative study of changes induced in transparent media of the guinea pig eye by parenteral administration of galactose].
Topics: Animals; Cataract; Cornea; Eye; Galactose; Guinea Pigs; Male; Vitreous Body | 1968 |
Failure to produce cataracts in rats with galactitol diet.
Topics: Animals; Carbohydrates; Cataract; Diet; Galactose; Lens, Crystalline; Liver; Ophthalmoscopy; Photography; Rats | 1969 |
Electrophoresis of soluble protein fraction in normal and cataractous lens (galactose fed) of albino rats.
Topics: Aging; Animals; Cataract; Diet; Electrophoresis; Eye Proteins; Galactose; Lens, Crystalline; Rats | 1969 |
Galactose cataract: changes in protein distribution during development.
Topics: Absorptiometry, Photon; Animals; Cataract; Crystallins; Eye Proteins; Galactose; Histocytochemistry; Lens, Crystalline; Male; Microradiography; Ophthalmoscopy; Rats; Time Factors | 1969 |
Methionyl-tRNA synthetase detected by [75Se]selenomethionine in lenses from normal and galactose-fed rats.
Topics: Animals; Cataract; Diet; Galactose; Lens, Crystalline; Ligases; Methionine; Protein Biosynthesis; Radioisotopes; Rats; Selenium | 1969 |
Electron microscopic study of galactose-induced cataract.
Topics: Animals; Biological Transport, Active; Body Fluids; Cataract; Cell Membrane Permeability; Cysts; Edema; Epithelium; Eye Neoplasms; Galactose; Lens, Crystalline; Microscopy, Electron; Rats; Ribosomes | 1969 |
Formation of cataracts by combinations of different factors.
Topics: Animals; Anterior Chamber; Cataract; Galactose; Lens, Crystalline; Naphthalenes; Pilocarpine; Rabbits; Rats | 1969 |
Heterozygous state of galactosemia with clinical signs of the disease?
Topics: Adult; Cataract; Child, Preschool; Erythrocytes; Female; Galactose; Galactosemias; Heterozygote; Humans; Infant; Male; Oxygen Consumption | 1969 |
Cataracts in galactosemia. The Jonas S. Friedenwald Memorial Lecture.
Topics: Adenosine Triphosphate; Alcohols; Amino Acids; Animals; Aqueous Humor; Cataract; Galactose; Galactosemias; Humans; Ion Exchange; Lens, Crystalline; Osmosis; Permeability; Potassium; Rats; Sodium | 1965 |
Topical corticosteroids and galactose cataracts.
Topics: Alcohols; Animals; Betamethasone; Cataract; Fructose-Bisphosphate Aldolase; Galactose; Galactosemias; Ophthalmic Solutions; Radioisotopes; Rats; Rubidium | 1965 |
Rubidium-86 accumulation and dulcitol distributions in lenses of galactose-fed rats.
Topics: Alcohols; Animals; Cataract; Dietary Carbohydrates; Galactose; In Vitro Techniques; Lens, Crystalline; Rats; Rubidium | 1965 |
Agar-gel electrophoresis of soluble lens proteins in galactose-fed rats.
Topics: Animals; Cataract; Crystallins; Dietary Carbohydrates; Electrophoresis; Eye Proteins; Galactose; In Vitro Techniques; Lens, Crystalline; Rats | 1965 |
[Experimental studies on infant nutrition. 28. Studies on milk products supplemented by galactose. 1. Results of nutritional experiments by feeding young albino rats with galactose-supplemented milk products].
Topics: Animals; Cataract; Galactose; Growth; In Vitro Techniques; Milk; Nutrition Disorders; Rats | 1965 |
Observations on the influence of orotic acid on galactose metabolism in congenital galactosemia.
Topics: Animals; Carbon Isotopes; Cataract; Galactose; Galactosemias; Humans; Orotic Acid; Rats | 1966 |
Changes in the water, protein, and glutathione contents of the lens in the course of galactose cataract development in rats.
Topics: Animals; Cataract; Eye Proteins; Galactose; Glutathione; Lens, Crystalline; Rats; Water | 1966 |
Energy metabolism in the lens during development of galactose cataract in rats.
Topics: Adenosine Triphosphate; Animals; Cataract; Galactose; Glycolysis; Lactates; Lens, Crystalline; Rats | 1966 |
Sugar cataracts, polyol levels and lens swelling.
Topics: Age Factors; Animals; Cataract; Galactose; Lens, Crystalline; Male; Rats; Xylose | 1966 |
Cataractogenic sugars.
Topics: Cataract; Hexoses; Pentoses | 1955 |
The sorbital pathway in the lens.
Topics: Cataract; Hexoses; Lens, Crystalline; Oxidoreductases; Sorbitol | 1962 |
Changes in the levels of protein & bound hexose during cataractogenesis.
Topics: Borohydrides; Buffers; Cataract; Eye Proteins; Hexoses; Humans; Oxidation-Reduction; Solubility | 1984 |
Nonenzymatic glucosylation of lens proteins in different types of cataracts.
Topics: Cataract; Crystallins; Diabetic Retinopathy; Hexoses; Humans; Lens, Crystalline | 1983 |
[Gas chromatographic analysis of free sugars and polyols in human cataractous lens (author's transl)].
Topics: Aged; Cataract; Chromatography, Gas; Hexoses; Humans; Lens, Crystalline; Sugar Alcohols | 1981 |
Effect of dietary taurine supplementation on GSH and NAD(P)-redox status, lipid peroxidation, and energy metabolism in diabetic precataractous lens.
Topics: Adenosine Triphosphate; Animals; Cataract; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Dietary Supplements; Energy Metabolism; Glutathione; Hexoses; Lens, Crystalline; Lipid Peroxidation; Male; Malondialdehyde; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sugar Alcohols; Taurine | 1999 |
The effect of an unsaturated-fat diet on cataract formation in streptozotocin-induced diabetic rats.
Topics: Animals; Aqueous Humor; Carbohydrate Metabolism; Cataract; Diabetes Mellitus; Dietary Fats; Eye; Fats, Unsaturated; Hexoses; Inositol; Lens, Crystalline; Lipid Metabolism; Liver; Male; Oils; Rats; Retina; Sorbitol; Streptozocin; Zea mays | 1976 |
Effect of in vitro glycosylation on the solubility of lens proteins.
Topics: Adult; Aged; Animals; Cataract; Crystallins; Goats; Hexoses; Humans; In Vitro Techniques; Infant; Mercaptoethanol; Middle Aged; Sheep; Solubility | 1986 |
[Biochemical studies on the etiology of cataract in diabetes].
Topics: Alcohol Oxidoreductases; Animals; Cataract; Cattle; Diabetes Complications; Diabetes Mellitus; Fructose; Glucose; Hexokinase; Hexoses; Lens, Crystalline; Sorbitol | 1970 |