galactosamine has been researched along with Liver Failure, Acute in 278 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 11 (3.96) | 18.2507 |
2000's | 69 (24.82) | 29.6817 |
2010's | 173 (62.23) | 24.3611 |
2020's | 25 (8.99) | 2.80 |
Authors | Studies |
---|---|
Baluchnejadmojarad, T; Mohamadi-Zarch, SM; Nazari-Serenjeh, M; Nourabadi, D; Ramazi, S; Roghani, M | 1 |
Huang, K; Kong, L; Liu, K; Meng, Q; Sun, H; Wang, C; Wang, L; Wang, S; Wang, X; Wu, J | 1 |
Cho, SB; Choi, YJ; Han, J; Hong, SG; Kang, D; Kang, SS; Kim, DR; Kim, EJ; Lee, DK; Nyiramana, MM; Siregar, AS; Woo, MS | 1 |
Chen, H; Dong, L; Dou, G; Liu, T; Wan, Y; Wang, X; Wu, C; Yang, Y; Yu, M; Zhai, H | 1 |
Hashimoto, Y; Hatta, M; Kaibori, M; Kotsuka, M; Nakatake, R; Nishizawa, M; Okumura, T; Okuyama, T; Sekimoto, M; Yoshida, T | 1 |
Ahmedy, OA; Ibrahim, SM; Salem, HH; Sayed, NH | 1 |
Fan, YC; Ji, XF; Sun, F; Wang, JW; Wang, K | 1 |
Dong, S; Jia, M; Li, S; Liu, G; Mu, W; Wang, Q; Yang, J | 1 |
Chen, Y; Fu, Y; Li, P; Sun, Y; Wang, J; Wang, X; Wu, H; Wu, Z; Yang, Z; Ye, Y; Zhou, E | 1 |
Bogunia, E; Czekaj, P; Grajoszek, A; Hermyt, M; Kolanko, E; Król, M; Limanówka, Ł; Michalik, M; Pająk, J; Prusek, A; Sikora, B; Skubis-Sikora, A | 1 |
Hwang, JI; Jung, HJ; Kang, JH; Kim, MW; Oh, SH; Park, SY; Seong, JK; Yoon, YS | 1 |
Jiang, YZ; Li, SP; Qu, W; Sun, J; Sun, LY; Tan, YL; Wei, L; Zeng, ZG; Zhou, GP; Zhu, ZJ | 1 |
Cai, L; Feng, L; Fu, Y; Gao, Y; Jiang, Z; Liu, S; Wang, Y; Xu, X; Zhang, L; Zhou, C | 1 |
Li, Y; Ma, J; Xu, Y; Zhang, M | 1 |
Chen, L; Pan, Y; Wang, H; Yang, J; Yuan, L | 1 |
He, Y; Sun, Q; Wang, L; Xu, H; Xue, Z; Zeng, Y; Zhang, Q | 1 |
Choi, I; Doh, KO; Jeong, JH; Kim, BK; Kim, HS; Kim, JO; Lee, DM; Moon, IJ; Nguyen, TT; Park, JB; Park, PH; Pathak, S; Regmi, S; Seo, Y; Sung, JH; Thanh, TP; Yong, CS; Yook, S | 1 |
Liu, Y; Pu, Z; Zhao, S | 1 |
Chen, X; Kachman, SD; Li, X; Liu, B; Lu, Y; Muthuraj, PG; Natarajan, SK; Pattabiraman, M; Yu, J; Zempleni, J | 1 |
Chen, J; Hao, J; Qi, T; Zhu, X | 1 |
Azuma, YT; Fujimoto, Y; Kuwamura, M | 1 |
Fan, XG; Hu, XW; Huang, Y; Huang, ZB; Li, N; Li, T; Pei, SY; Wang, Y; Zhou, D; Zhou, PC | 1 |
Bai, H; Ding, Y; Dou, X; Fan, Y; Han, C; Lai, P; Li, Y; Sheng, Q; Zhang, C | 1 |
Dong, W; Song, E; Song, Y | 1 |
Avni, D; Harikumar, KB; Sanyal, AJ; Spiegel, S | 1 |
Hu, K; Huang, J; Li, L; Li, S; Lu, H; Shao, R; Shen, Y; Tang, L; Yang, Y; Zhang, L | 1 |
Chen, Z; Li, A; Liu, Y; Lou, G; Xia, H; Yang, Q | 1 |
Hu, X; Jiang, R; Jiang, X; Ling, Q; Liu, H; Liu, Y; Wan, J; Wu, Q; Yan, L; Zhang, S | 1 |
Choi, JH; Cingolani, F; Czaja, MJ; Ilyas, G; Ravenelle, F; Tanaka, KE; Zhao, E | 1 |
Gao, HM; Li, Y; Lu, L; Luo, N; Wang, YQ | 1 |
Liu, YM; Lv, J; Ma, JH; Pan, YJ; Xie, XH; Yu, ZJ; Zeng, QL | 1 |
Chen, D; Dong, P; Duan, Z; Li, X; Lin, J; Ren, F; Shi, H; Sun, H; Zhang, X | 1 |
Cheng, ML; Hu, YX; Liu, HJ; Yu, L | 1 |
Finkin, S; Finkin-Groner, E; Weinstock, M; Zeeli, S | 1 |
Jiang, DR; Jiang, W; Zhang, X; Zhao, M; Zhou, AL | 1 |
Bergheim, I; Biedenbach, J; Galle, PR; Gehrke, N; Helmig, S; Huber, T; Huber, Y; Schattenberg, JM; Schuchmann, M; Schuppan, D; Simon, P; Straub, BK; Wörns, MA | 1 |
Chen, D; Chen, E; Li, J; Li, L; Lu, J; Wang, J; Wang, Y; Zhang, Y; Zhou, N; Zhu, D | 1 |
Kim, SJ; Lee, SM | 2 |
Agarwal, S; Chakraborty, S; Devaki, T; Pérez-Sánchez, H; Shaik Ibrahim, S; Sheriff, SA | 1 |
Chu, Y; Dong, L; Lu, J; Quan, H; Yin, L | 1 |
Gong, ZJ; Jiao, FZ; Wang, LW; Yang, F; Zhang, HY | 1 |
Gong, ZJ; Jiao, FZ; Wang, LW; Zhang, H; Zhang, HY; Zhang, WB | 1 |
Chen, C; Lei, L; Li, C; Li, Z; Ren, W; Su, Y; Xu, J; Yang, C | 1 |
Fan, Q; Li, R; Wang, Y; Wu, X; Xu, L; Ye, J; Zhang, M; Zhang, Y; Zhao, W; Zheng, X | 1 |
Cai, L; Feng, L; Gao, Y; He, GL; Jiang, ZS; Li, Y; Pan, MX; Peng, Q; Weng, J | 1 |
Dai, J; Ge, P; Jiang, R; Li, J; Yao, X; Zhang, L | 1 |
Chai, FN; Li, XG; Li, YF; Ma, WY; Xiang, HM; Xu, HS; Ye, XL; Zhang, J | 1 |
Beauchamp, J; Billon, C; Boulinguiez, A; Burris, TP; Delhaye, S; Dombrowicz, D; Duez, HM; Duhem, C; Eeckhoute, J; Ferri, L; Haas, JT; Lancel, S; Mayeuf-Louchart, A; Pourcet, B; Sebti, Y; Sitaula, S; Staels, B; Thorel, Q; Vanhoutte, J; Zecchin, M | 1 |
Chen, H; Chen, Q; Gong, ZJ; Jiao, FZ; Wang, Y; Zhang, WB | 1 |
Cao, P; Gong, X; Lin, Y; Liu, L; Luo, M; Wu, T; Yang, Q; Zhou, L | 1 |
Chen, E; Chen, Y; Li, J; Li, L; Lu, J; Shao, L; Wang, J; Xie, Z; Zhang, Y; Zhou, N | 1 |
Chen, YP; Li, SS; Lu, MQ; Ni, SL; Tang, XY; Yang, M; Yang, NB; Zhang, SG | 1 |
Chen, Y; Li, X; Xu, X; Yin, L; Zhang, W; Zhou, Y; Zhu, R | 1 |
Ci, X; Fan, X; Feng, H; Lv, H; Wang, L | 1 |
Ahmadi, AR; Anders, RA; Cameron, AM; Chicco, M; Creamer, TJ; Dor, FJMF; IJzermans, JNM; Sun, Z; Wesson, RN; Williams, GM | 1 |
Cai, E; Fu, T; Li, H; Li, P; Liu, J; Zhao, Y; Zhu, H | 1 |
Dai, W; Liu, P; Lu, H; Lu, X; Wang, D; Wang, J; Wang, W; Wang, Z | 1 |
Jia, A; Lin, H; Tao, L; Wen, J; Weng, D; Xu, X; Yang, Y; Zhang, J; Zhao, M | 1 |
Chen, Z; Li, A; Liu, Y; Lou, G; Qi, J; Ye, D; Zhang, T; Zheng, M | 1 |
Jiang, Y; Li, Y; Wang, N | 1 |
Chen, L; Duan, Z; Ren, F; Shi, H; Wang, H; Xie, B; Xu, L; Zhang, H; Zhang, X | 1 |
He, Y; Huang, D; Jin, L; Li, X; Wang, J; Xia, Z; Ye, X; Yu, D; Zhang, B | 1 |
Hata, T; Hori, T; Nguyen, JH; Rehman, F | 1 |
Cao, J; Chang, CH; Chen, PD; Huang, YJ; Lee, CY; Lee, HS; Wu, YM | 1 |
Chen, X; Ding, W; Fan, YY; Fu, L; Xu, DX; Zhang, C | 1 |
Chen, Y; Jiang, Q; Li, J; Long, F; Mao, D; Qiu, H; Shi, Q; Tang, N; Wang, M; Wang, X; Zhang, R | 1 |
Beauchamp, J; Duez, H; Ferri, L; Mogilenko, D; Pourcet, B; Sebti, Y; Staels, B; Zecchin, M | 1 |
An, B; Chen, G; Ji, X; Lyu, Z | 1 |
Chen, EQ; Luo, C; Tang, H; Tao, YC; Wang, ML; Wu, DB | 1 |
Choi, JS; Kang, JW; Kim, DW; Kim, YS; Lee, SM | 1 |
Gong, ZJ; Han, XQ; Li, X; Wang, LK; Wang, LW | 1 |
Gong, X; Jiang, R; Wan, JY; Wang, CD; Yin, XR; Zhang, L | 1 |
Dong, F; Feng, B; Gao, Y; Liu, F; Wei, L; Wu, S | 1 |
Gao, DY; Liang, DY; Liu, LM; Wang, YY; Yang, ZW; Ye, CG; Yu, FP; Zhao, L | 1 |
Ichinose, F; Lefer, D; Marutani, E; Shirozu, K; Tokuda, K; Wang, R | 1 |
Bao, S; Cai, W; Gao, T; Li, H; Tabassam, F; Wang, H; Wu, H; Xiang, X; Xie, Q; Xu, Y; Zhao, G | 1 |
El-Agamy, DS; Gamil, NM; Makled, MN | 1 |
Bai, T; Jiang, S; Jin, Q; Jin, X; Lian, LH; Nan, JX; Wu, YL; Yang, Y | 1 |
Chen, L; Hu, JH; Pang, F; Tong, JJ; Xin, SJ; Xu, ZH; Yang, HZ; Zhang, HY | 1 |
Enjoji, M; Kato, M; Kotoh, K; Masaki, Y; Miyazaki, M; Nakamuta, M; Takayanagi, R; Tanaka, K; Tanaka, M | 1 |
He, YW; Huang, SF; Liu, W; Wu, F | 1 |
Hayashi, M; Imai, Y; Jin, D; Komeda, K; Li, ZL; Okamura, H; Otsuki, Y; Takai, S; Tashiro, K; Uchiyama, K | 1 |
Gong, X; Jiang, R; Wan, J; Wang, B; Wang, C; Xu, G; Yin, X; Zhang, L | 1 |
Chen, Y; Duan, Z; Han, Y; Ren, F; Shi, H; Wei, L; Wen, T; Zhang, J; Zhang, X; Zheng, S | 1 |
Huang, Q; Huang, R; Liang, S; Lin, X; Tan, S; Wu, X; Zhang, S; Zhuo, L | 1 |
Abdin, MZ; Ahad, A; Farooqi, H; Ganai, AA; Jahan, S | 1 |
Chen, HL; Cheng, SM; Cheng, YJ; Lee, SD; Shyu, WC; Teng, YH | 1 |
Chen, H; Chen, LN; He, Y; Ji, WJ; Li, HY; Liu, JB; Liu, X; Wang, B; Yang, XF | 1 |
Ha, FU; Han, T; Liang, N; Nie, XH; Wang, SH; Xiang, HL; Zhu, ZY | 1 |
Ai, Q; Che, Q; Dai, J; Jia, M; Jiang, R; Jing, Y; Lin, L; Wan, J; Zhang, L; Zhou, D | 1 |
Chen, L; Jingjing, W; Li, C; Li, X; Ma, L; Peng, A; Wei, Z; Xie, C; Zeng, F | 1 |
Cho, HI; Kim, JS; Kim, SJ; Kim, YH; Kwak, JH; Lee, SK; Lee, SM; Park, JH | 1 |
Liu, P; Sun, CM; Wang, DL; Wang, HT; Wang, JB; Wang, ZH; Wen, Y; Wu, J; Zhao, YT | 1 |
Gong, ZJ; Han, XQ; Li, X; Wang, LK; Wang, LW; Yang, F | 1 |
Deng, WS; Gu, L; Jiang, CH; Liu, Y; Sun, LC; Sun, XF; Xu, Q; Zhou, H | 1 |
Hirai, S; Hisaka, S; Ichinose, F; Kaneki, M; Shirozu, K; Tanaka, T | 1 |
Fu, J; Hu, L; Jiang, X; Song, E; Song, Y; Su, C; Xia, X; Xu, D; Zhang, P | 1 |
Gong, X; Jiang, R; Kuang, G; Wan, J; Wang, B; Xu, G; Yin, X; Zhang, L | 1 |
Chen, H; Gao, Y; Gong, X; Huang, Y; Yang, F; Zhong, J; Zhou, B | 1 |
Chen, D; Chen, Y; Duan, Z; Piao, Z; Ren, F; Wang, X; Wen, T; Yang, B; Yin, J; Zhang, J; Zhang, X; Zheng, S | 1 |
Cho, HI; Kim, JS; Kim, SJ; Kwak, JH; Lee, DU; Lee, SK; Lee, SM | 1 |
Cho, HI; Choi, HS; Kwak, JH; Lee, DU; Lee, SK; Lee, SM; Park, JH | 1 |
Dong, P; Li, W; Lu, M; Ni, S; Xu, L; Yang, N; Zhang, S | 1 |
Dhawan, A; Filippi, C; Heaton, ND; Hughes, RD; Jitraruch, S; Lehec, SC; Longhi, MS; Mitry, RR; Philippeos, C; Soong, D | 1 |
El-Sayeh, BM; Kenawy, SA; Khalil, WK; Salem, HA; Sayed, RH | 1 |
Gao, M; Guo, C; Li, Y; Liu, X; Liu, Y; Ma, Y; Mao, H; Wang, X; Wei, Z; Zhang, L | 1 |
Chen, G; Hu, X; Lin, W; Luo, J; Wang, Y; Yi, C; Zhang, Y; Zhong, S; Zhu, H | 1 |
Duan, Z; Jiao, M; Ren, F; Zhao, C; Zhou, L | 1 |
Cheng, Y; Gao, Y; Jian, GD; Pan, MX; Zhang, Z; Zhao, YC | 1 |
Brytan, M; Dyrla, P; Kozłowski, W; Patera, J; Saracyn, M; Wańkowicz, Z; Wojtuń, S; Ząbkowski, T; Zdanowski, R | 1 |
Nagarkatti, M; Nagarkatti, PS; Tomar, S | 1 |
Chen, SL; Dong, JZ; Lu, MQ; Ni, SL; Shi, KQ; Wang, LP; Yang, NB; Zhang, SN; Zhu, JH | 1 |
Abshagen, K; Fehring, V; Kuhla, A; Schaeper, U; Schulze-Topphoff, U; Thrum, M; Vollmar, B | 1 |
Farooqi, H; Ganai, AA; Khan, AA; Malik, ZA | 1 |
Bai, L; Chen, EQ; Gong, DY; Tang, H | 1 |
Chen, D; Duan, Z; Li, Z; Ren, F; Shi, H; Wang, Z; Wen, T; Xie, B; Zhang, X; Zhou, L | 1 |
Cheng, N; Cheng, X; Huang, J; Lei, W; Li, X; Liu, B; Liu, J; Zhang, L | 1 |
Nagarkatti, M; Nagarkatti, PS; Tomar, S; Zumbrun, EE | 1 |
Liang, DY; Liu, LM; Tu, WJ; Ye, CG; Yu, FP; Zhao, L; Zhu, T | 1 |
Huang, H; Li, J; Zhang, X | 1 |
Chen, HL; Chen, YH; Chien, CS; Ho, CM; Ho, SL; Ho, YT; Hu, RH; Lee, PH | 1 |
Cao, HC; Li, J; Li, LJ; Pan, QL; Yang, JF; Yu, J | 1 |
Chen, R; Gong, X; Jiang, R; Kuang, G; Ma, L; Wan, J | 1 |
Chen, Y; Gao, J; Hu, Z; Li, J; Luo, M; Tian, D; Wang, C; Zhao, A | 1 |
Li, R; Liu, YM; Wang, XB; Yao, SS; Zeng, H; Zhang, JL; Zhou, XB; Zhu, LL | 1 |
Chen, LY; Duan, ZP; Ma, YJ; Ren, F; Yang, B; Zhou, L | 1 |
Fujii, H; Furuya, S; Hara, M; Hirayama, K; Kono, H; Sun, C | 1 |
Dong, S; Liu, F; Liu, H; Song, L; Wang, J; Wang, X; Wang, Y; Wu, C; Xie, J; Zhang, W; Zhao, S | 1 |
Cao, W; Shen, C; Su, M; Wang, W; Wang, Y; Zhao, C; Zhao, X | 1 |
Jaeschke, H; Maes, M; Vinken, M | 1 |
Lei, YC; Li, W; Luo, P; Yang, LL; Zheng, PF | 1 |
Lei, YC; Li, W; Luo, P; Yang, LL | 1 |
Li, H; Liu, BR; Pei, FH; Wang, XR; Yan, BZ; Yang, BS; Zhang, YF; Zhu, AC | 1 |
Cao, H; Chen, P; Chen, X; Ding, W; Hao, S; Jiang, J; Jiang, L; Jin, L; Li, J; Li, L; Li, M; Shi, D; Sun, S; Wu, T; Xin, J; Zhang, J; Zhang, L; Zhou, N; Zhou, Q | 1 |
Guo, L; Liu, Q; Shao, Q; Tang, Y; Yang, J; Zheng, S | 1 |
Choi, JW; Kim, IH; Kim, YM; Lee, MK; Nam, TJ | 1 |
Hu, XY; Lin, W; Luo, JX; Yang, F; Zhang, Y; Zhong, S | 1 |
Ai, G; Chen, X; Han, YQ; Huang, ZM; Liu, QC | 1 |
Lei, Y; Li, W; Luo, P | 1 |
Han, Y; Wu, Z; Zhu, J | 1 |
Bai, L; Chen, D; Chen, Y; Duan, Z; Li, L; Ren, F; Shi, H; Wen, T; Zhang, L; Zhang, X; Zheng, S | 1 |
Du, J; Wang, S; Wang, T; Wang, Z; Xia, L; Yang, P; Zhang, J; Zhou, M | 1 |
Gao, DY; Liang, DY; Liu, LM; Tan, ZL; Tu, WJ; Wang, XT; Zhong, H; Zhu, T | 1 |
Chen, D; Chen, Y; Duan, Z; Li, L; Ren, F; Shi, H; Wang, X; Zhang, L; Zhang, X; Zhao, C; Zheng, S; Zhou, L | 1 |
Ding, Y; Ma, H; Shi, X; Yuan, X; Zhang, Z; Zhao, X | 1 |
Bai, X; Buist-Homan, M; Cai, B; Cheng, H; Faber, KN; Jiang, J; Li, L; Luo, X; Moshage, H; Shen, D; Shi, G; Yang, P; Zhou, Q | 1 |
Chen, D; Ding, J; Gou, C; Li, L; Li, X; Liu, D; Lou, J; Ren, F; Wang, X; Wen, T; Yang, H; Zhang, X | 1 |
Ahamad, SR; Ahmad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Alkharfy, KM; Ansari, MA; Mohsin, K; Raish, M | 1 |
Ding, YT; Han, B; Huang, T; Huang, X; Ren, HZ; Sang, JF; Shi, XL | 1 |
Huang, X; Jiang, Y; Luo, M; Wan, M; Xu, S; Zhang, M; Zhang, P | 1 |
Farghali, H; Kgalalelo Kemelo, M; Kutinová Canová, N; Wojnarová, L | 1 |
Chen, L; Ge, K; Lei, YC; Li, W; Lu, CL; Wu, YH; Yang, LL | 1 |
Azevedo, RA; Éboli, LP; Goldenberg, A; Gonzalez, AM; Lanzoni, VP; Netto, AA; Paula, TS | 1 |
Chen, L; Wang, X; Xiang, B; Xiang, C | 1 |
Ahn, B; Cho, WJ; Choi, JH; Choi, YP; Han, SB; Hong, JT; Jung, JK; Kim, Y; Lee, H; Park, SH; Yeo, JH; Yun, CY | 1 |
Hu, D; Li, S; Lu, M; Ni, S; Tang, X; Yang, N; Zhang, S | 1 |
Chen, X; Gong, X; Jiang, R; Kuang, G; Wan, J; Wang, B; Yin, X; Zhang, L | 1 |
Gong, X; Huang, L; Wan, RZ; Yang, Y; Zhang, B; Zhang, P; Zhang, Q | 1 |
Bao, S; Chen, M; Cheng, Q; Huang, C; Li, N; Liu, C; Shi, G; Yu, K; Zhao, Q; Zheng, J; Zhu, M | 1 |
Han, YP; Yan, C; Zhou, L | 1 |
Agusti, A; Boix, J; Cauli, O; Felipo, V; Piedrafita, B; Rodrigo, R | 1 |
Han, QY; Kang, W; Lei, Y; Liu, ZW; Lou, S; Zhang, L | 1 |
Dong, F; Fang, J; Feng, B; Gao, Y; Li, Y; Liu, F; Lv, S; Wei, L; Wu, S; Yan, X | 1 |
DeFrances, MC; Gandhi, CR; Han, C; Li, G; Lim, K; Wu, T | 1 |
Chen, YP; Cui, YL; Lin, HL; Qiu, LX; Sun, QF; Zheng, MH | 1 |
Bortolatto, CF; Jesse, CR; Nogueira, CW; Savegnago, L; Wilhelm, EA | 1 |
Chen, J; Dong, L; Gao, S; Xia, S; Zhang, C; Zhang, J; Zuo, L | 1 |
Fukui, H; Kawaratani, H; Kitazawa, T; Tsujimoto, T | 2 |
Abshagen, K; Eipel, C; Kuhla, A; Menger, MD; Siebert, N; Vollmar, B | 1 |
Bi, MR; Chen, LY; Li, BX; Lu, YJ; Wang, W; Yan, BZ; Yang, BS | 1 |
Jesse, CR; Nogueira, CW; Roman, SS; Savegnago, L; Wilhelm, EA | 1 |
Alvarez, M; Culebras, JM; González-Gallego, J; Tuñón, MJ | 1 |
Chalaris, A; Drucker, C; Rabe, B; Rose-John, S; Scheller, J; Schulz, E | 1 |
Chang, MF; Chang, MH; Chen, HL; Chen, YH; Chien, CS; Yu, CH | 1 |
Crozier, A; Kawai, Y; Kumazawa, S; Matsui, A; Sakakibara, H; Shimoi, K; Terao, J; Yokoyama, A | 1 |
Jesse, CR; Nogueira, CW; Wilhelm, EA | 1 |
Liu, P; Lv, S; Song, HL | 1 |
Guo, JW; Luo, XP; Ning, Q; Xi, D; Yan, WM | 1 |
Jiang, YZ; Lian, LH; Nan, JX; Wu, YL | 1 |
Choi, JS; Jung, HA; Jung, JY; Kang, JW; Kim, JK; Kim, YS; Lee, SM; Lee, WC; Oh, WY | 1 |
Csizmadia, E; Da Silva, CG; Damrauer, SM; Daniel, S; Ferran, C; Longo, CR; Patel, VI; Ramsey, HE; Siracuse, JJ; Studer, P | 1 |
Ando, K; Sato, A; Shimizu, H; Sugiyama, A; Takeuchi, T | 1 |
Gong, X; Hu, N; Li, HZ; Li, XH; Luo, FL; Wan, JY; Wang, B; Wang, CD; Wu, MJ; Yang, JQ; Zhang, L | 1 |
Chen, HS; Dong, FT; Feng, B; Gao, Y; Liu, F; Lv, S; Wei, L; Wu, SM | 1 |
Kim, JK; Kim, SJ; Kwak, JH; Lee, DU; Lee, SM | 1 |
Hou, W; Liu, Z; Meng, QH; Piao, ZF; Zhang, HY | 1 |
Cui, W; Li, LX; Liu, P; Lv, S; Song, HL; Wang, W; Zhou, Y | 1 |
Huang, XF; Li, YM; Liu, QQ; Nie, QH; Wang, AH; Yang, J | 1 |
An, FM; Gong, BD; Guo, Q; Wang, H; Xie, Q; Yu, DS; Yu, H | 1 |
Feng, XC; Jiang, YZ; Lian, LH; Nan, JX; Wu, YL | 1 |
Cai, XF; Jin, X; Lee, JJ; Lian, LH; Nan, JX; Wu, YL | 1 |
Chen, Y; Ding, M; Duan, ZP; Liu, M; Liu, XH; Lv, ZW; Xu, WH; Zhao, J; Zheng, SJ | 1 |
Agusti, A; Boix, J; Cauli, O; Cerdán, S; Felipo, V; López-Larrubia, P; Nieto-Charques, L; Rodrigo, R | 1 |
Dai, XH; Fan, XG; Li, N; Liu, HB; Liu, XQ; Xiao, MF; Zhang, BX; Zhang, ZP; Zhong, BY; Zhou, RR; Zou, MX | 1 |
Lian, LH; Nan, JX; Song, SZ; Wan, Y; Wu, YL; Zheng, ZW | 1 |
Huang, CQ; Li, MH; Wan, HJ; Ye, J; Yin, MJ; Yu, J; Zhang, FT | 1 |
Chen, Y; Du, W; Li, L; Lv, G; Pan, X; Song, T; Xu, J; Yu, C; Zhang, A; Zhang, Y; Zhao, L | 1 |
Avlas, O; Ben-Ari, Z; Cheporko, Y; Greif, F; Hochhauser, E; Pappo, O; Ravid, A; Shapiro, R; Sharon, E; Zilbermints, V | 1 |
Bernardi, P; Brusilow, WS; Chiara, F; Jambekar, AA; Needleman, R; Nicolosi, L; Palma, E; Petronilli, V; Rasola, A | 1 |
Heiden, S; Hocher, B; Kalk, P; Pfab, T; Rahnenführe, J; von Websky, K | 1 |
Chu, XH; Ding, YT; Gu, JY; Han, B; Ren, HZ; Shi, XL; Tan, JJ; Xiao, JQ; Zhang, Y | 1 |
Gao, J; Liu, S; Wang, JX; Xing, WW; Xu, DG; Xu, T; Zou, MJ | 1 |
Choi, JS; Jung, HA; Kim, YS; Lee, SM; Lee, WC | 1 |
Chen, YP; Guo, CY; Lu, J; Wan, R; Wang, XP | 1 |
Chen, Y; Duan, Z; Guo, Y; Hu, J; Li, J; Qiao, F; Song, H; Sun, S; Tomlinson, S; Wu, Y; Xu, G; Yang, F; Yu, H; Zhao, G; Zhou, X; Zhou, Y | 1 |
Baine, AM; Chen, F; Gardner, LB; Hori, T; Nguyen, JH; Uemoto, S | 1 |
Chen, L; Deng, C; Li, X; Liu, J; Ma, L; Wang, G; Wang, X; Xie, C | 1 |
An, FM; Gong, BD; Lin, LY; Wang, H; Xiang, XG; Xie, Q; Yu, DS | 1 |
Gao, R; Li, W; Li, Y; Wu, Q; Zhu, C | 1 |
Avlas, O; Bachmetov, L; Ben Ari, Z; Cheporko, Y; Grief, F; Hochhauser, E; Pappo, O; Shainberg, A; Sharon, E; Zemel, R; Zilbermints, V | 1 |
Du, Z; Duan, C; Lin, Q; Qiu, L; Wang, C; Wang, H; Wang, J; Wang, Y; Wen, X | 1 |
Cheng, YW; Hsu, CA; Huang, CC; Lin, KJ; Shyur, LF; Yang, SS | 1 |
Bruno, S; Camussi, G; Fonsato, V; Gilbo, N; Grange, C; Herrera, MB; Romagnoli, R; Tetta, C | 1 |
Chu, XH; Ding, YT; Gu, JY; Gu, ZZ; Han, B; Ren, HZ; Shi, XL; Tan, JJ; Xiao, JQ; Yuan, XW; Zhang, Y | 1 |
Carson, DJ; Kulkarni, RM; Kutcher, LW; Leonis, MA; Stuart, WD; Waltz, SE | 1 |
Chen, L; Chen, Y; Duan, Z; Han, Y; Ma, Y; Piao, Z; Ren, F; Wen, T; Zhang, H; Zhang, J; Zheng, S; Zhou, L | 1 |
Bai, L; Chen, EQ; Gong, DY; Leng, XH; Liu, C; Tang, H; Wang, LC | 1 |
Deng, Y; Sun, L; Tang, J; Wang, W | 1 |
Bi, MR; Chen, LY; Kang, L; Wang, W; Wang, XR; Yan, BZ; Yang, BS | 1 |
Lopez, R; Mazariegos, GV; Patzer, JF | 1 |
Degen, SJ; Leonis, MA; Toney-Earley, K; Waltz, SE | 1 |
Kobayashi, N; Kodama, M; Kunieda, T; Kurabayashi, Y; Maruyama, M; Nakaji, S; Okitsu, T; Oshita, M; Shibata, N; Takesue, M; Tanaka, N; Totsugawa, T | 1 |
Aggarwal, S; Amiot, BP; Block, GD; Fulmer, ML; Gerber, D; Khanna, A; Kramer, DJ; Mazariegos, GV; Molmenti, E; Patzer, JF; Scott, VL; Wagner, RA; Yin, WY | 1 |
Collado, JA; Lozano, JM; Medina, T; Muntané, J | 1 |
Gao, Y; Jiang, HC; Sun, B; Xu, J | 1 |
Li, LJ; Sheng, JF; Wu, ZW; Xiao, DS | 1 |
Guo, Q; Xie, Q; Xu, YM; Yan, CG; Yu, H; Zhou, XQ | 1 |
Bi, MR; Chen, LY; Gao, F; Ma, YJ; Yang, BS | 1 |
Liu, P; Lü, S; Song, HL | 1 |
Beyaert, R; Bogaert, V; De Geest, B; El Bakkouri, K; Heyninck, K; Libert, C; Papeleu, P; Schotte, P; Van Huffel, S; Wielockx, B; Wullaert, A | 1 |
Peng, SF; Tan, DM; Zhu, HP | 1 |
Chen, HX; Li, HW; Peng, CH; Shu, M; Wu, WD; Xiao, WD; Zhang, MJ; Zhou, GW | 1 |
Guo, Q; Jiang, S; Li, GM; Liu, HF; Xie, Q; Yu, H; Zhou, HJ; Zhou, XQ | 1 |
Asada, K; Fukui, H; Ikenaka, Y; Kitade, M; Kojima, H; Nakamura, M; Namisaki, T; Noguchi, R; Sakurai, S; Uemura, M; Yamazaki, M; Yanase, K; Yoshii, J; Yoshiji, H | 1 |
Cao, HC; Chen, JJ; Chen, Y; Chen, YM; Du, WB; Li, J; Li, LJ; Pan, XP; Zhang, YM | 1 |
Endo, A; Goto, T; Kataoka, E; Mikami, K; Miura, K; Ohshima, S; Sato, M; Sato, W; Segawa, D; Shibuya, T; Takeuchi, S; Watanabe, D; Watanabe, S; Yoneyama, K; Yoshino, R | 1 |
Li, Y; Wang, H | 1 |
Nguyen, JH; Yamamoto, S | 1 |
Bermudez, J; Boada, J; Calafell, R; Cuesta, E; Perales, JC; Roig, T | 1 |
Lu, MH; Tan, DM; Xu, XW | 1 |
Deng, H; Liu, LM; Luo, J; Sun, SL; Xiong, GF; Zhang, JX | 1 |
Berthiaume, F; Harada, H; Kitajima, M; Kobayashi, N; Obara, H; Shimazu, M; Shimizu, N; Shinoda, M; Suganuma, K; Takayanagi, A; Tanaka, N; Tilles, AW; Tompkins, RG; Toner, M; Totsugawa, T; Wakabayashi, G; Yarmush, ML | 1 |
Amano, S; Harada, N; Ito, M; Kuwahata, M; Miyamoto, K; Oka, T; Segawa, H; Tatsumi, S; Tomoe, Y | 1 |
Fan, ST; Obed, A; Prantl, L; Schlitt, HJ; Siu, YT; Tsui, TY; Yet, SF | 1 |
Chen, H; Dong, F; Feng, B; Li, Y; Liu, F; Lv, S; Wei, L; Wu, S; Yan, X | 1 |
Cui, W; Liu, P; Wen, Y | 1 |
Abshagen, K; Eipel, C; Klemm, K; Le Minh, K; Menger, MD; Vollmar, B | 1 |
Chen, YB; Fan, ST; Ho, DW; Lam, DK; Ng, IO; To, J | 1 |
Gao, ZL; Tan, DM; Zhong, YD; Zhu, HP | 1 |
Adawi, D; Ahrné, S; Jeppsson, B; Molin, G; Osman, N | 1 |
Aishima, S; Enjoji, M; Fukui, Y; Higuchi, N; Kato, M; Kohjima, M; Kotoh, K; Nakamuta, M; Takayanagi, R | 1 |
Arteel, GE; Guo, L; McMullen, MR; Nagy, LE; Pritchard, MT; Roychowdhury, S | 1 |
Chen, JY; Deng, H; Guo, HX; Liu, LM; Luo, J; Sun, SL; Zhang, JX | 1 |
Hijikawa, T; Ishizaki, M; Kaibori, M; Kamiyama, Y; Kwon, AH; Matsui, K; Okumura, T; Ozaki, T; Tanaka, H; Tokuhara, K; Uchida, Y | 1 |
Chen, Y; Duan, ZP; Liu, XH; Lu, J; Song, CZ; Wang, TL; Zhang, J; Zhang, LJ | 1 |
Aggarwal, S; Lopez, RC; Patzer, JF | 1 |
Fujimoto, M; Fukui, H; Kawaratani, H; Kitazawa, T; Tsujimoto, T | 1 |
Duan, ZH; Li, XY; Lu, JW; Ning, H; Wang, H; Wei, W; Xu, DX; Yan-Li, J; Zhang, C; Zhang, H; Zhao, L | 1 |
Cai, XF; Jiang, YZ; Jin, HR; Jin, XJ; Lee, JJ; Lian, LH; Nan, JX | 1 |
Chen, Z; Lou, YJ; Ma, KF; Qi, LY; Yang, HY; Zhu, DY | 1 |
Arilla, E; Barrios, V; Boyano-Adánez, MD | 1 |
Kakisaka, A; Kasai, S; Kudo, K; Mito, M | 1 |
Hirai, S; Kasai, S; Mito, M | 1 |
Bengmark, S; Jeppsson, B; Kasravi, FB; Molin, G; Wang, L; Wang, XD | 1 |
Chang, CH; Chen, MF; Chuang, KL; Fu, SH; Hsu, BR; Jeng, LB; Lee, WC | 1 |
Kajiwara, K; Maezono, K; Maki, T; Mawatari, K; Shinkai, A | 1 |
Okita, K; Sakaida, I; Takenaka, K; Yasunaga, M | 1 |
Birraux, J; Genin, B; Le Coultre, C; Mage, R; Morel, P; Sinigaglia, C | 1 |
Farhood, A; Fisher, MA; Ho, YS; Jaeschke, H; Lawson, JA | 1 |
Bhargava, KK; Gupta, S; Irani, AN; Palestro, CJ; Rajvanshi, P | 1 |
De La Mata, M; Delgado, M; García, R; Lozano, JM; Miño, G; Montero, JL; Muntané, J; O'Valle, F; Pedraza, CA; Quintero, A; Rodríguez, FJ; Segado, O; Siendones, E | 1 |
Aoki, M; Fukamachi, H; Hanada, K; Hara, H; Morimoto, S; Sakai, Y; Shiokawa, K; Toyoda, Y; Uchida, S; Yoshimura, H | 1 |
Anilkumar, T; Aslam, M; Ben-Hamida, AJ; Courtney, JM; Gaylor, JD; Khorsandi, SE; Pusey, CD; Ryan, CJ | 1 |
Li, Z; Liu, S; Lu, H; Yu, Z; Zheng, M | 1 |
Asama, T; Iwamoto, J; Kasai, S; Kono, T; Kotani, H; Mamiya, N; Ohara, K; Yoneda, M | 1 |
Shiota, T; Tominaga, S; Tsuchida, T; Watanabe, A | 1 |
3 review(s) available for galactosamine and Liver Failure, Acute
Article | Year |
---|---|
Experimental models of hepatotoxicity related to acute liver failure.
Topics: Acetaminophen; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Concanavalin A; Disease Models, Animal; Fas Ligand Protein; Galactosamine; Humans; Liver Failure, Acute | 2016 |
In vitro and in vivo experimental hepatotoxic models in liver research: applications to the assessment of potential hepatoprotective drugs.
Topics: Animals; Biomedical Research; Disease Models, Animal; Down-Regulation; Drug Discovery; Galactosamine; Humans; Lipopolysaccharides; Liver Failure, Acute; Protective Agents; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Disease Models, Animal; Galactosamine; Hepatectomy; Humans; Liver Failure, Acute; Liver Regeneration | 2009 |
275 other study(ies) available for galactosamine and Liver Failure, Acute
Article | Year |
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Esculetin Alleviates Acute Liver Failure following Lipopolysaccharide/D-Galactosamine in Male C57BL/6 Mice.
Topics: Animals; Disease Models, Animal; Galactosamine; Interleukin-1beta; Interleukin-6; Iran; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Protective Factors; Toll-Like Receptor 4; Umbelliferones | 2021 |
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cells, Cultured; Chalcones; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Galactosamine; Inflammasomes; Inflammation Mediators; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice, Inbred C57BL; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction | 2021 |
Oyster-Derived Tyr-Ala (YA) Peptide Prevents Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure by Suppressing Inflammatory, Apoptotic, Ferroptotic, and Pyroptotic Signals.
Topics: Animals; Anti-Inflammatory Agents; Aquatic Organisms; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Ostreidae; Peptides; Pyroptosis; Signal Transduction | 2021 |
Recombinant Human HPS Protects Mice and Nonhuman Primates from Acute Liver Injury.
Topics: Animals; CHO Cells; Cricetulus; Cytokines; Drug Evaluation, Preclinical; Fibrinogen; Galactosamine; Humans; Lipopolysaccharides; Liver Failure, Acute; Macaca fascicularis; Male; Mice, Inbred BALB C; Oxidative Stress; Random Allocation; Rats, Sprague-Dawley; Recombinant Proteins; Toxicity Tests, Acute | 2021 |
Omeprazole Increases Survival Through the Inhibition of Inflammatory Mediaters in Two Rat Sepsis Models.
Topics: Animals; Cell Culture Techniques; Disease Models, Animal; Galactosamine; Hepatectomy; Hepatocytes; Inflammation Mediators; Liver Failure, Acute; Male; Nitric Oxide Synthase Type II; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Sepsis | 2022 |
Naringenin affords protection against lipopolysaccharide/D-galactosamine-induced acute liver failure: Role of autophagy.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Autophagy; Beclin-1; Caspase 3; Disease Models, Animal; Flavanones; Galactosamine; Humans; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Microtubule-Associated Proteins; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Signal Transduction; Superoxide Dismutase-1; Tumor Suppressor Protein p53 | 2022 |
Noncanonical Wnt5a/JNK Signaling Contributes to the Development of D-Gal/LPS-Induced Acute Liver Failure.
Topics: Animals; Cytokines; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha | 2022 |
Hepatoprotective Effects of Albumin-Encapsulated Nanoparticles of a Curcumin Derivative COP-22 against Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Injury in Mice.
Topics: Albumins; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Curcumin; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Nanoparticles; NF-kappa B | 2022 |
The protective effects of myricetin against acute liver failure via inhibiting inflammation and regulating oxidative stress via Nrf2 signaling.
Topics: Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Inflammation; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress | 2023 |
Dynamics of Acute Liver Injury in Experimental Models of Hepatotoxicity in the Context of Their Implementation in Preclinical Studies on Stem Cell Therapy.
Topics: Animals; Cell- and Tissue-Based Therapy; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Necrosis; Rats | 2022 |
Deficiency of Ninjurin1 attenuates LPS/D-galactosamine-induced acute liver failure by reducing TNF-α-induced apoptosis in hepatocytes.
Topics: Animals; Apoptosis; Caspases; Cell Adhesion Molecules, Neuronal; Endothelial Cells; Galactosamine; Hepatocytes; Humans; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Knockout; Nerve Growth Factors; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha | 2022 |
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure.
Topics: Alanine Transaminase; Albumins; alpha 1-Antitrypsin; Animals; Aspartate Aminotransferases; Child; Cytochrome P-450 CYP3A; Galactosamine; Glycogen; Hepatocytes; Humans; Interleukin-6; Keratin-18; Lipopolysaccharides; Liver Failure, Acute; Metabolic Diseases; Mice; Serum Albumin, Human; Tumor Necrosis Factor-alpha; Urea | 2022 |
Establishment of acute liver failure model in Tibetan miniature pig and verified by dual plasma molecular adsorption system.
Topics: Adsorption; Ammonia; Animals; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Necrosis; Swine; Swine, Miniature; Tibet | 2023 |
Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Geraniol alleviates acute liver failure.
Topics: Acyclic Monoterpenes; Animals; Cytokines; Galactosamine; Inflammasomes; Lipopolysaccharides; Liver Failure, Acute; Macrophages; Methylation; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; PPAR gamma; Signal Transduction | 2023 |
Identification of key immune-related genes associated with LPS/D-GalN-induced acute liver failure in mice based on transcriptome sequencing.
Topics: Animals; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Transcriptome | 2023 |
MicroRNA-181a-5p alleviates acute liver failure in mice by inhibiting HMGB1.
Topics: Animals; Apoptosis; Galactosamine; HMGB1 Protein; Lipopolysaccharides; Liver Failure, Acute; Mice; Microarray Analysis; MicroRNAs | 2023 |
Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity.
Topics: Animals; Cell Culture Techniques; Cell Survival; Dinoprostone; Disease Models, Animal; Galactosamine; Heme Oxygenase-1; Interleukin-10; Lipopolysaccharides; Liver; Liver Failure, Acute; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Nude; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase | 2019 |
Bone marrow mesenchymal stem cell-derived exosomes attenuate D-GaIN/LPS-induced hepatocyte apoptosis by activating autophagy in vitro.
Topics: Animals; Apoptosis; Autophagy; Bone Marrow Cells; Disease Models, Animal; Exosomes; Galactosamine; Hepatocytes; Inflammation; Lipopolysaccharides; Liver Failure, Acute; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rats | 2019 |
Protective Role of Shiitake Mushroom-Derived Exosome-Like Nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Exosomes; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophages; Mice; Nanoparticles; NLR Family, Pyrin Domain-Containing 3 Protein; Plant Extracts; Protective Agents; Shiitake Mushrooms | 2020 |
Comparative Proteomic Analyses of the Liver in D-Galactosamine-Sensitized Mice Treated with Different Toll-Like Receptor Agonists.
Topics: Animals; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice, Inbred C57BL; Proteins; Proteomics; Tandem Mass Spectrometry; Toll-Like Receptors | 2020 |
Deficiency of interleukin-19 exacerbates lipopolysaccharide/D-galactosamine-induced acute liver failure.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Galactosamine; Interleukins; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Rodent Diseases; Tumor Necrosis Factor-alpha | 2020 |
Melittin ameliorates inflammation in mouse acute liver failure via inhibition of PKM2-mediated Warburg effect.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Galactosamine; Glycolysis; Inflammation; Lipopolysaccharides; Liver Failure, Acute; Male; Melitten; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Protein Binding; Pyruvate Kinase; RAW 264.7 Cells | 2021 |
STAT6 up-regulation amplifies M2 macrophage anti-inflammatory capacity through mesenchymal stem cells.
Topics: Animals; Cell Communication; Cells, Cultured; Chemical and Drug Induced Liver Injury; Coculture Techniques; Disease Models, Animal; Galactosamine; Hepatocytes; Inflammation Mediators; Liver; Liver Failure, Acute; Macrophages; Male; Mesenchymal Stem Cell Transplantation; Phenotype; Rats, Wistar; Signal Transduction; STAT6 Transcription Factor; Up-Regulation | 2021 |
Co-administration of lipopolysaccharide and D-galactosamine induces genotoxicity in mouse liver.
Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; DNA Damage; Galactosamine; Hepatocytes; Lipopolysaccharides; Liver Failure, Acute; Male; Mice | 2021 |
Deletion or inhibition of SphK1 mitigates fulminant hepatic failure by suppressing TNFα-dependent inflammation and apoptosis.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Disease Models, Animal; Galactosamine; Hepatocytes; Inflammation; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice, Knockout; Phosphotransferases (Alcohol Group Acceptor); Tumor Necrosis Factor-alpha | 2021 |
Stattic alleviates acute hepatic damage induced by LPS/d-galactosamine in mice.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Caspases; Cyclic S-Oxides; Disease Models, Animal; Galactosamine; Humans; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2021 |
5-((7-Chloro-6-fluoro-1h-indol-3-yl) methyl)-3-methylimidazolidine-2,4-dione as a RIP1 inhibitor protects LPS/D-galactosamine-induced liver failure.
Topics: Animals; Galactosamine; GTPase-Activating Proteins; Humans; Indoles; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Necroptosis; Protective Agents; Reactive Oxygen Species; Signal Transduction; U937 Cells | 2021 |
CQMUH-011, a novel adamantane sulfonamide compound, inhibits lipopolysaccharide- and D-galactosamine-induced fulminant hepatic failure in mice.
Topics: Adamantane; Animals; Anti-Inflammatory Agents; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Macrophages; Male; Mice; Mice, Inbred BALB C; NF-kappa B; RAW 264.7 Cells; Signal Transduction; Sulfonamides; Toll-Like Receptor 4 | 2017 |
Pentamidine blocks hepatotoxic injury in mice.
Topics: Animals; Biopsy, Needle; Blotting, Western; Cytokines; Disease Models, Animal; Galactosamine; Immunohistochemistry; In Situ Nick-End Labeling; Lipopolysaccharides; Liver Failure, Acute; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Pentamidine; Random Allocation; Real-Time Polymerase Chain Reaction; Survival Rate | 2017 |
Inhibition of PI3K/AKt/mTOR signaling pathway protects against d-galactosamine/lipopolysaccharide-induced acute liver failure by chaperone-mediated autophagy in rats.
Topics: Animals; Autophagy; Female; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Male; Molecular Chaperones; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases | 2017 |
MiR-19a Affects Hepatocyte Autophagy via Regulating lncRNA NBR2 and AMPK/PPARα in D-GalN/Lipopolysaccharide-Stimulated Hepatocytes.
Topics: AMP-Activated Protein Kinase Kinases; Autophagy; Cell Line; Galactosamine; Hepatocytes; Humans; Lipopolysaccharides; Liver Failure, Acute; MicroRNAs; PPAR alpha; Protein Kinases; RNA, Long Noncoding; Signal Transduction | 2018 |
Peroxisome proliferator-activated receptor alpha mediates C/EBP homologous protein to protect mice from acute liver failure.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cells, Cultured; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophages; Male; Mice, Inbred C57BL; PPAR alpha; Transcription Factor CHOP | 2017 |
[Microflora changes in upper digestive tract and bile in acute liver failure mice].
Topics: Animals; Bile; Biodiversity; Galactosamine; Gastrointestinal Microbiome; Lactobacillaceae; Liver; Liver Failure, Acute; Mice | 2017 |
Indoline derivatives mitigate liver damage in a mouse model of acute liver injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Gene Expression Regulation; I-kappa B Kinase; Indoles; Interleukin-6; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase Kinases; Nitric Oxide; RAW 264.7 Cells; Transcription Factors; Tumor Necrosis Factor-alpha | 2017 |
Inhibitory effect of oxymatrine on hepatocyte apoptosis
Topics: Alanine Transaminase; Alkaloids; Animals; Apoptosis; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Galactosamine; Glycogen Synthase Kinase 3 beta; Hepatocytes; Humans; Interleukin-1beta; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Microscopy, Electron, Transmission; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinolizines; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
Voluntary distance running prevents TNF-mediated liver injury in mice through alterations of the intrahepatic immune milieu.
Topics: Alarmins; Animals; Body Weight; Chemokines; Chemotaxis; Cytokines; Enzyme Activation; Galactosamine; Inflammation; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Liver; Liver Failure, Acute; Liver Function Tests; Male; Mice, Inbred C57BL; Models, Animal; NF-kappa B; Physical Conditioning, Animal; Receptors, Pattern Recognition; Tumor Necrosis Factor-alpha | 2017 |
Dynamic changes of plasma metabolites in pigs with GalN-induced acute liver failure using GC-MS and UPLC-MS.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Galactosamine; Gas Chromatography-Mass Spectrometry; Liver; Liver Failure, Acute; Metabolic Networks and Pathways; Metabolome; Metabolomics; Multivariate Analysis; Sus scrofa | 2017 |
Necrostatin-1 Protects Against D-Galactosamine and Lipopolysaccharide-Induced Hepatic Injury by Preventing TLR4 and RAGE Signaling.
Topics: Alarmins; Animals; Galactosamine; Imidazoles; Indoles; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Protective Agents; Receptor for Advanced Glycation End Products; Receptors, Pattern Recognition; Signal Transduction; Toll-Like Receptor 4 | 2017 |
Lycopene Prevents Mitochondrial Dysfunction during d-Galactosamine/Lipopolysaccharide-Induced Fulminant Hepatic Failure in Albino Rats.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Binding Sites; Carotenoids; Chemical and Drug Induced Liver Injury; Citric Acid Cycle; Electron Transport Chain Complex Proteins; Galactosamine; Hydrogen Peroxide; Lipid Peroxidation; Lipopolysaccharides; Lipoxygenase Inhibitors; Lipoxygenases; Liver; Liver Failure, Acute; Lycopene; Male; Mitochondria; Molecular Docking Simulation; Oxidative Stress; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Rats; Rats, Wistar | 2017 |
Hepatoprotective Effects of Kaempferol-3-O-α-l-Arabinopyranosyl-7-O-α-l-Rhamnopyranoside on d-Galactosamine and Lipopolysaccharide Caused Hepatic Failure in Mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Elaeagnaceae; Galactosamine; Gene Expression Regulation; Glycosides; Kaempferols; Lipopolysaccharides; Liver; Liver Failure, Acute; Malondialdehyde; Mice; NF-kappa B; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptor 4 | 2017 |
[Protective effect of the histone deacetylase inhibitor ACY1215 against brain edema in mice with acute liver failure].
Topics: Animals; Aspartate Aminotransferases; Brain Edema; Galactosamine; Histone Deacetylase Inhibitors; Liver; Liver Failure, Acute; Mice; NF-kappa B; Tumor Necrosis Factor-alpha | 2017 |
Histone deacetylase 6 inhibitor ACY-1215 protects against experimental acute liver failure by regulating the TLR4-MAPK/NF-κB pathway.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cytokines; Disease Models, Animal; Galactosamine; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Hydroxamic Acids; Inflammation; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4 | 2018 |
Protective effects of oxymatrine against lipopolysaccharide/D‑galactosamine‑induced acute liver failure through oxidative damage, via activation of Nrf2/HO‑1 and modulation of inflammatory TLR4‑signaling pathways.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Galactosamine; Gene Expression; Glutathione Peroxidase; Heme Oxygenase-1; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Malondialdehyde; Membrane Proteins; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Quinolizines; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
Berberine protects acute liver failure in mice through inhibiting inflammation and mitochondria-dependent apoptosis.
Topics: Animals; Apoptosis; Berberine; Cytoprotection; Galactosamine; Inflammation; Liver Failure, Acute; Male; Mice; Mice, Inbred ICR; Mitochondria; NF-kappa B; RAW 264.7 Cells; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
Novel D-galactosamine-induced cynomolgus monkey model of acute liver failure.
Topics: Ammonia; Animals; Disease Models, Animal; Galactosamine; Intracranial Pressure; Liver Failure, Acute; Macaca fascicularis; Male; Saphenous Vein | 2017 |
Diminazene aceturate alleviated lipopolysaccharide/D-galactosamine-induced fulminant hepatitis in mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Caspases; Chemical and Drug Induced Liver Injury; Diminazene; Galactosamine; Hepatitis; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Tumor Necrosis Factor-alpha | 2018 |
Protective effect of Coptisine from Rhizoma Coptidis on LPS/D-GalN-induced acute liver failure in mice through up-regulating expression of miR-122.
Topics: Animals; Berberine; Coptis chinensis; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Galactosamine; Gene Expression; Hep G2 Cells; Humans; Lipopolysaccharides; Liver Failure, Acute; Mice; MicroRNAs; Protective Agents; Random Allocation; Treatment Outcome; Up-Regulation | 2018 |
Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.
Topics: Animals; Caspase 1; Cells, Cultured; Chemical and Drug Induced Liver Injury; Circadian Rhythm; Cytokines; Disease Models, Animal; Galactosamine; Genetic Predisposition to Disease; Inflammasomes; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophage Activation; Macrophages, Peritoneal; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Nuclear Receptor Subfamily 1, Group D, Member 1; Peritonitis; Phenotype; Pyrrolidines; RNA Interference; Severity of Illness Index; Signal Transduction; Thiophenes; Time Factors; Transfection | 2018 |
The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway.
Topics: Animals; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Galactosamine; Histone Deacetylase 2; Intestinal Mucosa; Intestines; Lipopolysaccharides; Liver Failure, Acute; Myeloid Differentiation Factor 88; Rats; Real-Time Polymerase Chain Reaction; Toll-Like Receptor 4 | 2018 |
Tamoxifen Prevents D-galactosamine/Lipopolysaccharide-Induced Murine Acute Hepatic Failure through Inhibition of Oxidative Stress and Mmd-2 Upregulation.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antigens, Differentiation; Antioxidants; Aspartate Aminotransferases; Catalase; Galactosamine; Glutathione Peroxidase; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Oxidative Stress; Superoxide Dismutase; Tamoxifen; Up-Regulation | 2018 |
Transcriptome Analysis of Porcine PBMCs Reveals the Immune Cascade Response and Gene Ontology Terms Related to Cell Death and Fibrosis in the Progression of Liver Failure.
Topics: Animals; Cell Death; Disease Progression; Galactosamine; Gene Expression Profiling; Gene Ontology; Leukocytes, Mononuclear; Liver Cirrhosis; Liver Failure, Acute; Male; Sequence Analysis, RNA; Signal Transduction; Swine; Transcriptome | 2018 |
Dendritic cells with increased expression of suppressor of cytokine signaling 1(SOCS1) gene ameliorate lipopolysaccharide/d-galactosamine-induced acute liver failure.
Topics: Animals; Bone Marrow Cells; Dendritic Cells; Galactosamine; HMGB1 Protein; Lentivirus; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Suppressor of Cytokine Signaling 1 Protein; Survival Analysis; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
Macrophage-targeting and reactive oxygen species (ROS)-responsive nanopolyplexes mediate anti-inflammatory siRNA delivery against acute liver failure (ALF).
Topics: Animals; Anti-Inflammatory Agents; Galactosamine; Gene Expression Regulation; Humans; Injections, Intravenous; Lectins, C-Type; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mannans; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Polyethyleneimine; RAW 264.7 Cells; Reactive Oxygen Species; Receptors, Cell Surface; RNA, Small Interfering; Selenium; Tumor Necrosis Factor-alpha | 2018 |
Daphnetin alleviates lipopolysaccharide/d-galactosamine-induced acute liver failure via the inhibition of NLRP3, MAPK and NF-κB, and the induction of autophagy.
Topics: Animals; Autophagy; Cytokines; Disease Models, Animal; Female; Galactosamine; Gene Expression Regulation; Inflammation Mediators; Lipopolysaccharides; Liver Failure, Acute; Liver Function Tests; Mice; Mitogen-Activated Protein Kinases; Models, Biological; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Protective Agents; Signal Transduction; Umbelliferones | 2018 |
Stem Cell Mobilization Is Lifesaving in a Large Animal Preclinical Model of Acute Liver Failure.
Topics: Animals; Benzylamines; Cyclams; Disease Models, Animal; Flow Cytometry; Galactosamine; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Immunohistochemistry; Liver Failure, Acute; Male; Swine | 2018 |
Hepatoprotective effect of α-mangostin against lipopolysaccharide/d-galactosamine-induced acute liver failure in mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Heme Oxygenase-1; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Membrane Proteins; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction; Toll-Like Receptor 4; Xanthones | 2018 |
Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure.
Topics: Ammonia; Analysis of Variance; Animals; Brain; Cation Transport Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Gene Expression Regulation; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha | 2018 |
Piceatannol attenuates D-GalN/LPS-induced hepatoxicity in mice: Involvement of ER stress, inflammation and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Endoplasmic Reticulum Stress; Female; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Stilbenes | 2018 |
AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages.
Topics: Animals; Biomarkers; Carrier Proteins; Cell Communication; Disease Models, Animal; Exosomes; Galactosamine; Inflammasomes; Lipopolysaccharides; Liver Failure, Acute; Macrophage Activation; Macrophages; Mesenchymal Stem Cells; Mice; MicroRNAs; NLR Family, Pyrin Domain-Containing 3 Protein; Thioredoxins | 2018 |
Geraniol protects against lipopolysaccharide and D-galactosamine-induced fulminant hepatic failure by activating PPARγ.
Topics: Acyclic Monoterpenes; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Galactosamine; Interleukin-1beta; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oils, Volatile; Plant Oils; PPAR gamma; Protective Agents; Signal Transduction; Terpenes; Tumor Necrosis Factor-alpha | 2019 |
Kaempferol protects mice from d-GalN/LPS-induced acute liver failure by regulating the ER stress-Grp78-CHOP signaling pathway.
Topics: Animals; Apoptosis; Cells, Cultured; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Galactosamine; Heat-Shock Proteins; Hepatocytes; Kaempferols; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Signal Transduction; Transcription Factor CHOP | 2019 |
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Flavonoids; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; NF-kappa B; Structure-Activity Relationship | 2019 |
GABA, γ-Aminobutyric Acid, Protects Against Severe Liver Injury.
Topics: Aminosalicylic Acids; Animals; Benzenesulfonates; Disease Models, Animal; Galactosamine; gamma-Aminobutyric Acid; Humans; Injections, Intraperitoneal; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Necrosis; Protective Agents; Signal Transduction; STAT3 Transcription Factor; Treatment Outcome; Tumor Necrosis Factor-alpha | 2019 |
Therapeutic Potential of Plasma Proteins Derived from Umbilical Cord Blood for Acute Liver Failure.
Topics: Adiponectin; Animals; Apoptosis; Blood Proteins; Cell Line; Cell Proliferation; Disease Models, Animal; Fetal Blood; Galactosamine; Hepatocytes; Humans; Liver; Liver Failure, Acute; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred F344; Survival Rate; Treatment Outcome | 2019 |
Obeticholic acid differentially regulates hepatic injury and inflammation at different stages of D-galactosamine/lipopolysaccharide-evoked acute liver failure.
Topics: Animals; Cell Death; Chenodeoxycholic Acid; Female; Galactosamine; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; NF-kappa B | 2019 |
The underlying mechanisms of Jie-Du-Hua-Yu granule for protecting rat liver failure.
Topics: Animals; Cell Proliferation; Drugs, Chinese Herbal; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Male; Medicine, Chinese Traditional; Rats; Rats, Wistar | 2019 |
The LPS/D-Galactosamine-Induced Fulminant Hepatitis Model to Assess the Role of Ligand-Activated Nuclear Receptors on the NLRP3 Inflammasome Pathway In Vivo.
Topics: Animals; Galactosamine; Gene Expression; Hepatitis; Humans; Inflammasomes; Kupffer Cells; Lipopolysaccharides; Liver Failure, Acute; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Receptors, Cytoplasmic and Nuclear; Signal Transduction | 2019 |
Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Furans; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Signal Transduction; Toll-Like Receptor 4 | 2019 |
Apolipoprotein A5 alleviates LPS/D-GalN-induced fulminant liver failure in mice by inhibiting TLR4-mediated NF-κB pathway.
Topics: Animals; Apolipoprotein A-V; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Galactosamine; Humans; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; NF-kappa B; Signal Transduction; Toll-Like Receptor 4 | 2019 |
Scoparone attenuates D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure through inhibition of toll-like receptor 4 signaling in mice.
Topics: Adaptor Proteins, Vesicular Transport; Alanine Transaminase; Animals; Artemisia; Coumarins; Galactosamine; Hepatocytes; Interferon-beta; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Liver Failure, Acute; Mice; Myeloid Differentiation Factor 88; NF-kappa B; Phosphorylation; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2013 |
Ethyl pyruvate prevents inflammatory factors release and decreases intestinal permeability in rats with D-galactosamine-induced acute liver failure.
Topics: Animals; Anti-Inflammatory Agents; Bacterial Translocation; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Endotoxins; Galactosamine; Inflammation Mediators; Intestinal Mucosa; Liver; Liver Failure, Acute; Male; Permeability; Pyruvates; Rats; Rats, Wistar; Time Factors | 2013 |
Hepatoprotective effects of syringin on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Eleutherococcus; Galactosamine; Glucosides; Lipopolysaccharides; Liver Failure, Acute; Liver Function Tests; Mice; Mice, Inbred BALB C; Phenylpropionates; Protective Agents; Survival Analysis | 2014 |
Metabonomic analysis of liver tissue from BALB/c mice with D-galactosamine/lipopolysaccharide-induced acute hepatic failure.
Topics: Amino Acids; Animals; Disease Models, Animal; Fatty Acids; Galactosamine; Gas Chromatography-Mass Spectrometry; Heptoses; Hexoses; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Maltose; Metabolome; Metabolomics; Mice; Mice, Inbred BALB C | 2013 |
Inhibition of UII/UTR system relieves acute inflammation of liver through preventing activation of NF-κB pathway in ALF mice.
Topics: Animals; Cytokines; Galactosamine; Inflammation; Inflammation Mediators; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice, Inbred BALB C; NF-kappa B; Peptide Fragments; Receptors, G-Protein-Coupled; Signal Transduction; Urotensins | 2014 |
Cystathionine γ-lyase deficiency protects mice from galactosamine/lipopolysaccharide-induced acute liver failure.
Topics: Animals; Apoptosis; Caspase 3; Cell Survival; Cystathionine gamma-Lyase; Disease Models, Animal; Galactosamine; Gene Expression Regulation; Hepatocytes; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophages, Peritoneal; Male; Membrane Potential, Mitochondrial; Mice; Models, Biological; NF-E2-Related Factor 2; Oxidation-Reduction; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Quinone Reductases; Sulfides; Thiosulfates; Tumor Necrosis Factor-alpha | 2014 |
Amelioration of liver injury by continuously targeted intervention against TNFRp55 in rats with acute-on-chronic liver failure.
Topics: Animals; Galactosamine; Humans; Immunoglobulin Fc Fragments; Lipopolysaccharides; Liver; Liver Failure; Liver Failure, Acute; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Serum Albumin; Tumor Necrosis Factor Decoy Receptors | 2013 |
Protective effects of agmatine against D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure in mice.
Topics: Agmatine; Animals; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Protective Agents | 2014 |
NLRP3 inflammasome activation in D-galactosamine and lipopolysaccharide-induced acute liver failure: role of heme oxygenase-1.
Topics: Animals; Carrier Proteins; Caspase 1; Galactosamine; Glutathione; Heme Oxygenase-1; Inflammasomes; Interleukin-1beta; Lipid Peroxidation; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Membrane Proteins; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Tumor Necrosis Factor-alpha | 2013 |
Hepatoprotective effect of cryptotanshinone from Salvia miltiorrhiza in D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Caspases; Chemical and Drug Induced Liver Injury; Cytochromes c; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Mitochondria; Mitogen-Activated Protein Kinases; NF-kappa B; Phenanthrenes; Phytotherapy; Plant Extracts; Salvia miltiorrhiza; Tumor Necrosis Factor-alpha | 2014 |
[Orthogonal design based optimization of a mouse model of acute liver failure induced by D-galactosamine and lipopolysaccharide].
Topics: Animals; Apoptosis; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL | 2013 |
Intrahepatic microcirculatory disorder, parenchymal hypoxia and NOX4 upregulation result in zonal differences in hepatocyte apoptosis following lipopolysaccharide- and D-galactosamine-induced acute liver failure in rats.
Topics: Aldehydes; Animals; Apoptosis; Caspase 3; Disease Models, Animal; Fluconazole; Galactosamine; Hepatocytes; Hypoxia-Inducible Factor 1; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophages; Male; Microcirculation; NADPH Oxidase 4; NADPH Oxidases; Nitroimidazoles; Oxidative Stress; Rats; Rats, Wistar; Rhodamines; Up-Regulation | 2014 |
[Protective effect of recombinant TM-N and recombinant soluble RAGE in a mouse model of acute hepatic failure].
Topics: Animals; Disease Models, Animal; Galactosamine; Interleukin-1beta; Liver; Liver Failure, Acute; Mice; Mice, Inbred Strains; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Recombinant Proteins; Thrombomodulin; Tumor Necrosis Factor-alpha | 2013 |
Chymase inhibition attenuates lipopolysaccharide/ d-galactosamine-induced acute liver failure in hamsters.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chymases; Galactosamine; Gene Expression; Interleukin-1beta; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Malondialdehyde; Matrix Metalloproteinase 9; Mesocricetus; Peroxidase; Sulfonamides; Thiophenes; Tumor Necrosis Factor-alpha | 2014 |
Synthetic RGDS peptide attenuated lipopolysaccharide/D-galactosamine-induced fulminant hepatic failure in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Chemokine CXCL2; Focal Adhesion Kinase 1; Galactosamine; Injections, Intraperitoneal; Integrins; Lipopolysaccharides; Liver Failure, Acute; Mice, Inbred BALB C; NF-kappa B; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Peroxidase; Signal Transduction; Tumor Necrosis Factor-alpha | 2014 |
Oxidative stress promotes D-GalN/LPS-induced acute hepatotoxicity by increasing glycogen synthase kinase 3β activity.
Topics: Adult; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Line; Female; Galactosamine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hepatitis B, Chronic; Humans; Lipopolysaccharides; Liver Failure, Acute; Male; Mice, Inbred C57BL; Middle Aged; Oxidative Stress | 2014 |
Protective effect of tormentic acid from Potentilla chinensis against lipopolysaccharide/D-galactosamine induced fulminant hepatic failure in mice.
Topics: Animals; Anti-Inflammatory Agents; Caspases; Cytochromes c; Cytokines; Galactosamine; Heme Oxygenase-1; Lipid Peroxidation; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Phytotherapy; Potentilla; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Transcription Factor RelA; Triterpenes | 2014 |
Glycine propionyl l-carnitine attenuates d-Galactosamine induced fulminant hepatic failure in wistar rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Ataxia Telangiectasia Mutated Proteins; Base Sequence; Carnitine; Comet Assay; DNA Primers; Galactosamine; Glutathione; Glycine; Lipid Peroxidation; Liver Failure, Acute; Male; Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2014 |
Cordyceps sinensis prevents apoptosis in mouse liver with D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure.
Topics: Animals; Apoptosis; Aspartate Aminotransferases; Caspases; Cordyceps; Disease Models, Animal; Galactosamine; Gene Expression; Injections, Intraperitoneal; Interleukin-10; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Phytotherapy; Plant Extracts; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Hepatoprotective effects of erythropoietin on D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; Epoetin Alfa; Erythropoietin; Galactosamine; Glutathione Peroxidase; Lipopolysaccharides; Liver; Liver Failure, Acute; Malondialdehyde; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinase; Protective Agents; Receptors, Erythropoietin; Recombinant Proteins; RNA, Messenger; Superoxide Dismutase | 2014 |
Comparison of the effects of the pretreatment and treatment with RhIL-11 on acute liver failure induced by D-galactosamine.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Drug Administration Schedule; Galactosamine; Humans; Interleukin-11; Liver; Liver Failure, Acute; Male; Proliferating Cell Nuclear Antigen; Protective Agents; Rats, Sprague-Dawley; Recombinant Proteins; Time Factors | 2014 |
Rotenone, a mitochondrial respiratory complex I inhibitor, ameliorates lipopolysaccharide/D-galactosamine-induced fulminant hepatitis in mice.
Topics: Animals; Apoptosis; Caspases; Down-Regulation; Electron Transport Complex I; Energy Metabolism; Galactosamine; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Rotenone; Transaminases; Tumor Necrosis Factor-alpha; Uncoupling Agents | 2014 |
Protective effect of SKLB010 against D-galactosamine/lipopolysaccharide-induced acute liver failure via nuclear factor-κB signaling pathway in macrophages.
Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Female; Galactosamine; Hepatocytes; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophages; Mice; Mice, Inbred BALB C; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protective Agents; RNA, Messenger; Signal Transduction; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2014 |
Protective effect of linarin against D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure.
Topics: Alanine Transaminase; Animals; Apoptosis; Apoptosis Regulatory Proteins; Aspartate Aminotransferases; Bcl-2-Like Protein 11; bcl-X Protein; Caspase 3; Caspase 8; Cytochromes c; Cytoprotection; Cytosol; Fas-Associated Death Domain Protein; Galactosamine; Glycosides; Interferon-gamma; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Membrane Proteins; Mice; Phosphorylation; Proteolysis; Proto-Oncogene Proteins; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2014 |
Tumor necrosis factor-alpha-induced reduction of glomerular filtration rate in rats with fulminant hepatic failure.
Topics: Animals; Antibodies; Blotting, Western; Boron Compounds; Calcium; Galactosamine; Gene Expression; Glomerular Filtration Rate; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kidney Glomerulus; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
Sodium butyrate protects against toxin-induced acute liver failure in rats.
Topics: Animals; Biomarkers; Butyric Acid; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Galactosamine; HMGB1 Protein; Inflammation Mediators; Interferon-gamma; Intestinal Mucosa; Intestines; Lipopolysaccharides; Liver; Liver Failure, Acute; Permeability; Protective Agents; Rats, Wistar; Serum Albumin; Serum Albumin, Human; Time Factors; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Ellagic acid protects Lipopolysaccharide/D-galactosamine-induced acute hepatic injury in mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Ellagic Acid; Galactosamine; Heme Oxygenase-1; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; Protective Agents; Tumor Necrosis Factor-alpha | 2014 |
Farnesyltransferase inhibitor, tipifarnib, prevents galactosamine/lipopolysaccharide-induced acute liver failure.
Topics: Animals; Caspase 3; Cell Survival; Cytokines; Endotoxemia; Enzyme Inhibitors; Farnesyltranstransferase; Galactosamine; Gene Expression Regulation; Hepatocytes; Inflammation; Interleukin-6; Lipids; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Quinolones; Sepsis; Tumor Necrosis Factor-alpha | 2014 |
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Caspases; Catalase; Cytokines; Galactosamine; Glutathione Peroxidase; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Thioctic Acid | 2014 |
Emodin ameliorated lipopolysaccharide-induced fulminant hepatic failure by blockade of TLR4/MD2 complex expression in D-galactosamine-sensitized mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Emodin; Extracellular Signal-Regulated MAP Kinases; Galactosamine; Gene Expression Regulation; Humans; Immunization; Lipopolysaccharides; Liver Failure, Acute; Lymphocyte Antigen 96; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2014 |
[Establishment of a rat model of acute liver failure by a modified 90% bloodless hepatectomy and by D-galactosamine and lipopolysaccharide injection].
Topics: Animals; Disease Models, Animal; Galactosamine; Hepatectomy; Injections, Intraperitoneal; Lipopolysaccharides; Liver Failure, Acute; Rats; Rats, Sprague-Dawley | 2014 |
[Role of endoplasmic reticulum stress in D-GalN/LPS-induced acute liver failure].
Topics: Animals; Apoptosis; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL | 2014 |
Protective effects of lupeol against D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure in mice.
Topics: Alanine Transaminase; Animals; Campanulaceae; Galactosamine; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Models, Biological; Molecular Structure; NF-kappa B; Pentacyclic Triterpenes; Plant Roots; Republic of Korea; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2014 |
Protective mechanisms of acacetin against D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure in mice.
Topics: Animals; Flavones; Galactosamine; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Molecular Structure; NF-kappa B; Phosphorylation; Plant Components, Aerial; Republic of Korea; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2014 |
Pretreatment of lipopolysaccharide (LPS) ameliorates D-GalN/LPS induced acute liver failure through TLR4 signaling pathway.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Drug Administration Schedule; Drug Tolerance; Galactosamine; Inflammation Mediators; Interleukin-1 Receptor-Associated Kinases; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Toll-Like Receptor 4; Transcription Factor RelA | 2014 |
Alginate microencapsulated hepatocytes optimised for transplantation in acute liver failure.
Topics: Alginates; Animals; Cell Survival; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Galactosamine; Glucuronic Acid; Hepatocytes; Hexuronic Acids; Humans; Leukocytes, Mononuclear; Liver Failure, Acute; Liver Regeneration; Male; Microspheres; Rats; Rats, Sprague-Dawley; Transplantation, Heterologous | 2014 |
Sulforaphane increases the survival rate in rats with fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Caspase 3; Catalase; Fas Ligand Protein; fas Receptor; Galactosamine; Glutathione; Glutathione Peroxidase; Heme Oxygenase-1; Injections, Intraperitoneal; Interleukin-10; Interleukin-6; Isothiocyanates; Lipid Peroxidation; Lipopolysaccharides; Liver Failure, Acute; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfoxides; Superoxide Dismutase; Superoxide Dismutase-1; Survival Rate; Transaminases; Tumor Necrosis Factor-alpha | 2014 |
Pretreatment with wortmannin alleviates lipopolysaccharide/d-galactosamine-induced acute liver injury.
Topics: Alanine Transaminase; Androstadienes; Animals; Apoptosis; Aspartate Aminotransferases; Autophagy; Chemical and Drug Induced Liver Injury; Cytokines; Galactosamine; Hepatocytes; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Necrosis; Phosphoinositide-3 Kinase Inhibitors; Wortmannin | 2014 |
The effects of modified sini decoction on liver injury and regeneration in acute liver failure induced by D-galactosamine in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Caspase 3; Chemical and Drug Induced Liver Injury; Cholinesterases; Drugs, Chinese Herbal; Galactosamine; HMGB1 Protein; Liver; Liver Failure, Acute; Male; NF-kappa B; Phytotherapy; Protective Agents; Prothrombin Time; Rats, Wistar; Regeneration; RNA, Messenger; Toll-Like Receptor 4 | 2015 |
[The protective role of peroxisome proliferator activated receptors-α and pathomechanism in D-galactosamine/lipopolysaccharide- induced acute liver failure in rats].
Topics: Animals; Cytokines; Disease Models, Animal; Galactosamine; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred C57BL; PPAR alpha; Rats; Tumor Necrosis Factor-alpha | 2014 |
Hybrid bioartificial liver support in cynomolgus monkeys with D-galactosamine-induced acute liver failure.
Topics: Animals; Biomarkers; Bioreactors; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Equipment Design; Feasibility Studies; Galactosamine; Hepatocytes; Humans; Liver; Liver Failure, Acute; Liver Function Tests; Liver, Artificial; Macaca fascicularis; Male; Time Factors | 2014 |
Hepatoprotective effect of nitric oxide in experimental model of acute hepatic failure.
Topics: Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Galactosamine; Liver; Liver Failure, Acute; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats, Sprague-Dawley; Signal Transduction; Time Factors | 2014 |
3,3'-Diindolylmethane attenuates LPS-mediated acute liver failure by regulating miRNAs to target IRAK4 and suppress Toll-like receptor signalling.
Topics: Alanine Transaminase; Animals; Caspase 3; Cell Line; Chemokine CCL2; Female; Galactosamine; Indoles; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophage Activation; Mice, Inbred C57BL; MicroRNAs; Protective Agents; Signal Transduction; Toll-Like Receptors; Tumor Necrosis Factor-alpha | 2015 |
LPS pretreatment ameliorates D-galactosamine/lipopolysaccharide-induced acute liver failure in rat.
Topics: Animals; Cytokines; Disease Models, Animal; Endotoxins; Galactosamine; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction; Specific Pathogen-Free Organisms; Suppressor of Cytokine Signaling Proteins; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
Liver-specific Fas silencing prevents galactosamine/lipopolysaccharide-induced liver injury.
Topics: Animals; Apoptosis; Fas Ligand Protein; fas Receptor; Galactosamine; Gene Silencing; Humans; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL | 2015 |
Genistein modulates the expression of NF-κB and MAPK (p-38 and ERK1/2), thereby attenuating d-Galactosamine induced fulminant hepatic failure in Wistar rats.
Topics: Animals; Galactosamine; Gene Expression Regulation; Genistein; Liver Failure, Acute; Male; MAP Kinase Signaling System; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Random Allocation; Rats; Rats, Wistar | 2015 |
Employment of digital gene expression profiling to identify potential pathogenic and therapeutic targets of fulminant hepatic failure.
Topics: Animals; Apoptosis; Chemokine CCL3; Chemokine CCL4; Disease Models, Animal; Galactosamine; Gene Expression Profiling; Gene Expression Regulation; Gene Library; High-Throughput Nucleotide Sequencing; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; NF-kappa B p50 Subunit; RNA, Messenger; Signal Transduction; Software; Tumor Necrosis Factor-alpha | 2015 |
Endoplasmic reticulum stress-activated glycogen synthase kinase 3β aggravates liver inflammation and hepatotoxicity in mice with acute liver failure.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Endoplasmic Reticulum Stress; Galactosamine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hepatocytes; Indoles; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophages; Male; Maleimides; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Neutrophil Infiltration; NF-kappa B; Peroxidase; Phenylbutyrates; Tumor Necrosis Factor-alpha; Tunicamycin | 2015 |
[Expression of intestinal defensin-5, soluble phospholipase A2 and lysozyme and the relation to bacterial translocation in rat models of acute liver failure].
Topics: Animals; Bacterial Translocation; Defensins; Disease Models, Animal; Galactosamine; Injections, Intraperitoneal; Intestines; Liver Failure, Acute; Male; Muramidase; Phospholipases A2; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2014 |
Protective role of cannabinoid receptor 2 activation in galactosamine/lipopolysaccharide-induced acute liver failure through regulation of macrophage polarization and microRNAs.
Topics: Animals; Apoptosis; Cannabinoids; Cytokines; Down-Regulation; Female; Galactosamine; Interleukin-1 Receptor-Associated Kinases; Liver; Liver Failure, Acute; Macrophages; Mice; Mice, Inbred C57BL; MicroRNAs; Phenotype; Receptor, Cannabinoid, CB2; Signal Transduction; Toll-Like Receptor 4 | 2015 |
Effects of urotensin-II on cytokines in early acute liver failure in mice.
Topics: Animals; Disease Models, Animal; Galactosamine; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice, Inbred BALB C; Peptide Fragments; Receptors, G-Protein-Coupled; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Urotensins | 2015 |
Protective effect of oroxylin A against lipopolysaccharide and/or D-galactosamine-induced acute liver injury in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Flavonoids; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; Peroxidase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
Transplantation speed offers early hepatocyte engraftment in acute liver injured rats: A translational study with clinical implications.
Topics: Animals; Disease Models, Animal; Galactosamine; Green Fluorescent Proteins; Hepatocytes; Humans; Liver; Liver Failure, Acute; Liver Transplantation; Male; Portal Vein; Rats; Rats, Sprague-Dawley; Time Factors; Translational Research, Biomedical | 2015 |
Mesenchymal stem cells from the human umbilical cord ameliorate fulminant hepatic failure and increase survival in mice.
Topics: Albumins; alpha-Fetoproteins; Alu Elements; Animals; Antigens, CD; Cell Differentiation; Cord Blood Stem Cell Transplantation; Galactosamine; Humans; Keratin-18; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Failure, Acute; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, SCID; Necrosis; Osteopontin; RNA, Messenger; Survival Rate; Tumor Necrosis Factor-alpha | 2015 |
Sesamin ameliorates lipopolysaccharide/d-galactosamine-induced fulminant hepatic failure by suppression of Toll-like receptor 4 signaling in mice.
Topics: Animals; Antioxidants; Cell Line; Dioxoles; Galactosamine; Lignans; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Protective Agents; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
Acute liver injury attenuation of a novel recombinant sTNFR through blocking hepatic apoptosis.
Topics: Animals; Apoptosis; Caspase 3; Female; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha | 2015 |
Xijiao Dihuang Decoction () and Rehmannia glutinosa Libosch. protect mice against lipopolysaccharide and tumor necrosis factor alpha-induced acute liver failure.
Topics: Animals; Apoptosis; Cytokines; Drugs, Chinese Herbal; Galactosamine; Hepatocytes; Lipopolysaccharides; Liver Failure, Acute; Male; Mice, Inbred C57BL; Protective Agents; Rehmannia; Tumor Necrosis Factor-alpha | 2019 |
Promotion of mitochondrial energy metabolism during hepatocyte apoptosis in a rat model of acute liver failure.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Bilirubin; Carnitine O-Palmitoyltransferase; Citrate (si)-Synthase; Electron Transport Complex IV; Energy Metabolism; Galactosamine; Gene Expression Regulation; Hepatocytes; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Signal Transduction | 2015 |
Interleukin 17A plays a role in lipopolysaccharide/D-galactosamine-induced fulminant hepatic injury in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Body Weight; Cytokines; Galactosamine; HMGB1 Protein; Intercellular Adhesion Molecule-1; Interleukin-17; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice, Inbred C57BL; Mice, Knockout; Neutrophils | 2015 |
Protective effects of sea buckthorn polysaccharide extracts against LPS/d-GalN-induced acute liver failure in mice via suppressing TLR4-NF-κB signaling.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Fruit; Galactosamine; Hippophae; Interleukin-1beta; Liver; Liver Failure, Acute; Male; Mice, Inbred C57BL; NF-kappa B; Plant Extracts; Polysaccharides; Protective Agents; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
[Role of the Notch signaling pathway in development of acute liver failure in a mouse model].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; Galactosamine; HMGB1 Protein; Lipopolysaccharides; Liver Failure, Acute; Mice; RAW 264.7 Cells; Receptors, Notch; RNA, Messenger; Signal Transduction | 2015 |
Inhibition of sphingosine kinase 1 ameliorates acute liver failure by reducing high-mobility group box 1 cytoplasmic translocation in liver cells.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytoplasm; Cytoprotection; Disease Models, Animal; Down-Regulation; Galactosamine; HMGB1 Protein; Kupffer Cells; Liver; Liver Failure, Acute; Male; Mice, Inbred BALB C; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Protein Transport; Signal Transduction; Sphingosine; Time Factors | 2015 |
Sphingosine kinase 1 dependent protein kinase C-δ activation plays an important role in acute liver failure in mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Biomarkers; Disease Models, Animal; Enzyme Activation; Galactosamine; Inflammation Mediators; Leukocytes, Mononuclear; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice, Inbred BALB C; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C-delta; Protein Kinase Inhibitors; Signal Transduction; Time Factors | 2015 |
The therapeutic effect of CORM-3 on acute liver failure induced by lipopolysaccharide/D-galactosamine in mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Bilirubin; Biomarkers; Chemical and Drug Induced Liver Injury; Cytokines; Cytoprotection; Disease Models, Animal; Galactosamine; Inflammation Mediators; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice, Inbred C57BL; Organometallic Compounds; Transcription Factor RelA | 2016 |
Quantitative evaluation of human bone mesenchymal stem cells rescuing fulminant hepatic failure in pigs.
Topics: Animals; Bone Marrow Transplantation; Cytokines; Disease Models, Animal; Galactosamine; Hepatocytes; Humans; Intracellular Signaling Peptides and Proteins; Liver; Liver Failure, Acute; Male; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Paracrine Communication; Rats; Rats, Sprague-Dawley; Survival Rate; Swine | 2017 |
Effect of bone marrow mesenchymal stem cells transplantation on the serum and liver HMGB1 expression in rats with acute liver failure.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Blotting, Western; Bone Marrow Transplantation; Disease Models, Animal; Down-Regulation; Galactosamine; HMGB1 Protein; Immunohistochemistry; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mesenchymal Stem Cell Transplantation; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 2015 |
Pyropia yezoensis glycoprotein regulates antioxidant status and prevents hepatotoxicity in a rat model of D-galactosamine/lipopolysaccharide-induced acute liver failure.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Cyclooxygenase 2; Disease Models, Animal; Galactosamine; Lipid Peroxidation; Lipopolysaccharides; Liver Failure, Acute; Male; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase Type II; Oxidative Stress; Phosphorylation; Plant Extracts; Protective Agents; Rats; Rhodophyta | 2016 |
Improved prescription of taohechengqi-tang alleviates D-galactosamine acute liver failure in rats.
Topics: Animals; Biomarkers; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Drugs, Chinese Herbal; Galactosamine; Gene Expression Regulation; HMGB1 Protein; Liver; Liver Failure, Acute; Liver Regeneration; Male; Proliferating Cell Nuclear Antigen; Rats, Wistar; RNA, Messenger; Signal Transduction | 2016 |
The protective effect of total phenolics from Oenanthe Javanica on acute liver failure induced by D-galactosamine.
Topics: Animals; Dose-Response Relationship, Drug; Galactosamine; Liver Failure, Acute; Male; Mice; Oenanthe; Oxidative Stress; Phenols; Phytotherapy; Plant Extracts; Silymarin | 2016 |
[Association between protective effect of Liuwei Wuling tablets against acute liver injury and its inhibitory effect on cytoplasmic translocation of high-mobility group box-1 in hepatocytes in mice].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Complement C3a; Complement C5a; Cytoplasm; Drugs, Chinese Herbal; Galactosamine; Hepatocytes; HMGB1 Protein; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Protein Transport; Tablets; Tumor Necrosis Factor-alpha | 2016 |
[Ephedra protects rats against acute liver failure induced by D-galactosamine and lipopolysaccharide].
Topics: Animals; Disease Models, Animal; Ephedra; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Protective Agents; Rats | 2016 |
Inhibition of glycogen synthase kinase 3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptor α.
Topics: Animals; Autophagy; Galactosamine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Isoenzymes; Lipopolysaccharides; Liver Failure, Acute; Mice; PPAR alpha; Signal Transduction; Sirolimus | 2016 |
PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice.
Topics: Anilides; Animals; Cell Movement; Chemokines; Cytokines; Galactosamine; Immunity, Innate; Kupffer Cells; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Period Circadian Proteins; PPAR gamma; Protein Binding; Receptors, CCR2; Up-Regulation | 2016 |
IRF3 is an important molecule in the UII/UT system and mediates immune inflammatory injury in acute liver failure.
Topics: Active Transport, Cell Nucleus; Adenoviridae; Animals; Galactosamine; Inflammation; Interferon Regulatory Factor-3; Interferon-beta; Interferon-gamma; Interleukin-6; Kupffer Cells; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Small Interfering; Transcription Factor RelA; Urotensins | 2016 |
Peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure.
Topics: Animals; Apoptosis; Down-Regulation; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Galactosamine; Hepatitis B virus; Hepatocytes; Lipopolysaccharides; Liver Failure, Acute; Male; Mice, Inbred C57BL; Phenylbutyrates; PPAR alpha; Pyrimidines; Transcription Factor CHOP | 2016 |
Combined treatment with MSC transplantation and neutrophil depletion ameliorates D-GalN/LPS-induced acute liver failure in rats.
Topics: Animals; Combined Modality Therapy; Cytokines; Galactosamine; Immune Sera; Lipopolysaccharides; Liver Failure, Acute; Mesenchymal Stem Cell Transplantation; Neutropenia; Neutrophils; Rats, Wistar | 2016 |
The protective effect of the natural compound hesperetin against fulminant hepatitis in vivo and in vitro.
Topics: Animals; Biological Products; Concanavalin A; Dose-Response Relationship, Drug; Galactosamine; Hesperidin; In Vitro Techniques; Lipopolysaccharides; Liver Failure, Acute; Male; Protective Agents; Rats; Rats, Wistar | 2017 |
Qingchangligan formula attenuates the inflammatory response to protect the liver from acute failure induced by d-galactosamine/lipopolysaccharide in mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Cytokines; Drugs, Chinese Herbal; Galactosamine; Hepatocytes; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Phytotherapy | 2017 |
Hepatoprotective activity of Lepidium sativum seeds against D-galactosamine/lipopolysaccharide induced hepatotoxicity in animal model.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Galactosamine; Lepidium sativum; Lipopolysaccharides; Liver; Liver Failure, Acute; Liver Function Tests; Male; Phytotherapy; Plant Preparations; Protective Agents; Rats, Wistar; Seeds | 2016 |
Intraportal mesenchymal stem cell transplantation prevents acute liver failure through promoting cell proliferation and inhibiting apoptosis.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Galactosamine; Liver; Liver Failure, Acute; Liver Function Tests; Liver Regeneration; Mesenchymal Stem Cell Transplantation; Phenotype; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Swine; Swine, Miniature; Time Factors | 2016 |
Tamoxifen Attenuates Lipopolysaccharide/Galactosamine-induced Acute Liver Failure by Antagonizing Hepatic Inflammation and Apoptosis.
Topics: Animals; Apoptosis; Caspase 3; Chemical and Drug Induced Liver Injury; Galactosamine; Humans; Interleukin-1beta; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Tamoxifen; Transaminases; Tumor Necrosis Factor-alpha | 2017 |
C5a/C5aR pathway is essential for up-regulating SphK1 expression through p38-MAPK activation in acute liver failure.
Topics: Animals; Blotting, Western; Complement C5a; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Galactosamine; HMGB1 Protein; Interleukin-1beta; Interleukin-6; Kaplan-Meier Estimate; Leukocytes, Mononuclear; Lipopolysaccharides; Liver; Liver Failure, Acute; Lysophospholipids; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; p38 Mitogen-Activated Protein Kinases; Phosphotransferases (Alcohol Group Acceptor); Random Allocation; Real-Time Polymerase Chain Reaction; Receptor, Anaphylatoxin C5a; RNA, Messenger; Signal Transduction; Sphingosine; Tumor Necrosis Factor-alpha | 2016 |
Evaluating the best time to intervene acute liver failure in rat models induced by d-galactosamine.
Topics: Animals; Apoptosis; Disease Models, Animal; Female; Galactosamine; Injections, Intraperitoneal; Liver; Liver Failure, Acute; Rats; Rats, Wistar; Time Factors | 2016 |
Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure.
Topics: Angiopoietin-2; Animals; Apoptosis; Cells, Cultured; Cytokines; Exosomes; Female; Galactosamine; Hepatocytes; Humans; Intercellular Adhesion Molecule-1; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Menstruation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Osteoprotegerin; Particle Size | 2017 |
Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Caffeic Acids; Cyclohexylamines; Disease Models, Animal; Galactosamine; Gene Expression Regulation; I-kappa B Kinase; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Docking Simulation; Phosphorylation; RAW 264.7 Cells; Shock, Septic | 2017 |
Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model.
Topics: Acute-On-Chronic Liver Failure; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Disease Models, Animal; Galactosamine; Interferon-gamma; Interleukin-10; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Rats; Rats, Sprague-Dawley; T-Lymphocytes, Regulatory; Th17 Cells | 2017 |
Glycyrrhetinic acid attenuates lipopolysaccharide-induced fulminant hepatic failure in d-galactosamine-sensitized mice by up-regulating expression of interleukin-1 receptor-associated kinase-M.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Dose-Response Relationship, Drug; Galactosamine; Glycyrrhetinic Acid; Interleukin-1 Receptor-Associated Kinases; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Up-Regulation | 2017 |
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Aspartate Aminotransferases; Caspases; Cells, Cultured; Drugs, Chinese Herbal; Galactosamine; Humans; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred Strains; NF-kappa B; Nitric Oxide Synthase Type II; Signal Transduction | 2017 |
Interleukin-23 mediates the pathogenesis of LPS/GalN-induced liver injury in mice.
Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Galactosamine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interleukin-17; Interleukin-23; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Receptors, Interleukin; Survival Analysis; Tumor Necrosis Factor-alpha | 2017 |
Contribution of hepatic stellate cells and matrix metalloproteinase 9 in acute liver failure.
Topics: Animals; Carbon Tetrachloride; Caspase 3; Chemical and Drug Induced Liver Injury; Collagen Type IV; Disease Models, Animal; Extracellular Matrix; Galactosamine; Gene Expression Regulation, Enzymologic; Hepatic Stellate Cells; Interleukin-1; Lipopolysaccharides; Liver; Liver Failure, Acute; Longevity; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Necrosis; Rats; Rats, Wistar; RNA, Messenger | 2008 |
Acute liver failure-induced death of rats is delayed or prevented by blocking NMDA receptors in brain.
Topics: Ammonia; Animals; Brain; Disease Models, Animal; Disease Progression; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Galactosamine; Hepatic Encephalopathy; Hyperammonemia; Infusion Pumps, Implantable; Liver Failure, Acute; Male; Memantine; Microdialysis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Time Factors | 2008 |
[Effects of granulocyte colony-stimulating factor on hepatocyte apoptosis in acute liver failure: experiment with rats].
Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Female; Flow Cytometry; Galactosamine; Granulocyte Colony-Stimulating Factor; Hepatocytes; Immunohistochemistry; Injections, Intraperitoneal; Liver Failure, Acute; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2008 |
Dynamic metabonomic analysis of BALB/c mice with different outcomes after D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure.
Topics: Adult; Animals; Chromatography, Gas; Female; Galactosamine; Humans; Least-Squares Analysis; Lipopolysaccharides; Liver Failure, Acute; Male; Mass Spectrometry; Metabolomics; Mice; Mice, Inbred BALB C; Middle Aged | 2008 |
Transgenic expression of cyclooxygenase-2 in hepatocytes accelerates endotoxin-induced acute liver failure.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Caspase 3; Caspase 9; Chronic Disease; Cyclooxygenase 2; Galactosamine; Gene Expression; Hemorrhage; Hepatitis; Hepatocytes; Humans; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 9; Necrosis; Organ Specificity; Poly(ADP-ribose) Polymerases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Signal Transduction; Transgenes; Up-Regulation | 2008 |
Mixed microencapsulation of rat primary hepatocytes and Sertoli cells improves the metabolic function in a D-galactosamine and lipopolysaccharide-induced rat model of acute liver failure.
Topics: Animals; Capsules; Cell Culture Techniques; Cell Line; Disease Models, Animal; Galactosamine; Hepatocytes; Immune Tolerance; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Rats; Recovery of Function; Sertoli Cells | 2009 |
Selective blockade of mGlu5 metabotropic glutamate receptors is hepatoprotective against fulminant hepatic failure induced by lipopolysaccharide and D-galactosamine in mice.
Topics: Alanine Transaminase; Animals; Ascorbic Acid; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Excitatory Amino Acid Antagonists; Galactosamine; Glutathione Transferase; Injections, Intraperitoneal; Lipid Peroxidation; Lipopolysaccharides; Liver Failure, Acute; Mice; Protective Agents; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Survival Analysis | 2009 |
Reduction of liver tumor necrosis factor-alpha expression by targeting delivery of antisense oligonucleotides into Kupffer cells protects rats from fulminant hepatitis.
Topics: Animals; Chitosan; Drug Carriers; Female; Galactosamine; Gene Targeting; Gene Transfer Techniques; Humans; Kupffer Cells; Lipopolysaccharides; Liver; Liver Failure, Acute; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Survival Rate; Tumor Necrosis Factor-alpha | 2009 |
Therapeutic approach to regulate innate immune response by Toll-like receptor 4 antagonist E5564 in rats with D-galactosamine-induced acute severe liver injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Galactosamine; Lipid A; Liver Failure, Acute; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2009 |
Role of the perforin/granzyme cell death pathway in D-Gal/LPS-induced inflammatory liver injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Etanercept; Galactosamine; Granzymes; Immunoglobulin G; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Pore Forming Cytotoxic Proteins; Receptors, Tumor Necrosis Factor; RNA, Messenger; Signal Transduction; T-Lymphocytes, Cytotoxic; Time Factors; Transaminases; Tumor Necrosis Factor-alpha | 2009 |
Role of cathepsin B-mediated apoptosis in fulminant hepatic failure in mice.
Topics: Animals; Apoptosis; Cathepsin B; Dipeptides; DNA Primers; Galactosamine; Immunohistochemistry; In Situ Nick-End Labeling; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred Strains; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2009 |
Hepatoprotective effect of 3-alkynyl selenophene on acute liver injury induced by D-galactosamine and lipopolysaccharide.
Topics: Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Galactosamine; Glutathione Transferase; Humans; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Molecular Structure; Organoselenium Compounds; Porphobilinogen Synthase; Rats; Rats, Wistar | 2009 |
Interleukin-6 trans-signaling regulates glycogen consumption after D-galactosamine-induced liver damage.
Topics: Animals; Cytokine Receptor gp130; Galactosamine; Glycogen; Humans; Interleukin-6; Liver Cirrhosis, Experimental; Liver Failure, Acute; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Animal; Protein Engineering; Recombinant Fusion Proteins; Signal Transduction | 2009 |
Impaired hepatocyte regeneration in acute severe hepatic injury enhances effective repopulation by transplanted hepatocytes.
Topics: Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Hepatic Stellate Cells; Hepatocyte Growth Factor; Hepatocytes; Liver Failure, Acute; Liver Regeneration; Male; Matrix Metalloproteinase 2; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Transforming Growth Factor alpha; Up-Regulation | 2009 |
Quercetin metabolites and protection against peroxynitrite-induced oxidative hepatic injury in rats.
Topics: Animals; Galactosamine; Humans; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Oxidative Stress; Peroxynitrous Acid; Quercetin; Rats; Rats, Sprague-Dawley; Tyrosine | 2009 |
Protective effect of p-methoxyl-diphenyl diselenide in lethal acute liver failure induced by lipopolysaccharide and D-galactosamine in mice.
Topics: Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Benzene Derivatives; Catalase; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Galactosamine; Glutathione Transferase; Injections, Intraperitoneal; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Organoselenium Compounds | 2009 |
The roles of tumor necrosis factor-alpha in colon tight junction protein expression and intestinal mucosa structure in a mouse model of acute liver failure.
Topics: Animals; Antibodies, Anti-Idiotypic; Colon; Disease Models, Animal; Galactosamine; Intestinal Mucosa; Lipopolysaccharides; Liver Failure, Acute; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Peritonitis; Phosphoproteins; RNA, Messenger; Tumor Necrosis Factor-alpha; Zonula Occludens-1 Protein | 2009 |
[Establishment of pig acute liver failure model and the role of pig fibrinogen-like protein 2].
Topics: Animals; Disease Models, Animal; Fibrinogen; Galactosamine; Immunohistochemistry; Liver; Liver Failure, Acute; Liver Function Tests; Male; Polymerase Chain Reaction; Random Allocation; RNA, Messenger; Swine | 2009 |
Hepatoprotective effects of salidroside on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Phenols; Tumor Necrosis Factor-alpha | 2009 |
Palmatine attenuates D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Berberine Alkaloids; Caspase 3; Coptis; Cytokines; Galactosamine; Glutathione; In Situ Nick-End Labeling; Lipid Peroxidation; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred ICR; Plant Roots; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis | 2010 |
A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression.
Topics: Animals; Cell Division; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cysteine Endopeptidases; Fatty Liver; Galactosamine; Gene Expression; Hepatectomy; Hepatocytes; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Liver Failure, Acute; Liver Transplantation; Mice; Mice, Inbred BALB C; Mice, Knockout; Necrosis; Oxidants; PPAR alpha; Reperfusion Injury; Tumor Necrosis Factor alpha-Induced Protein 3 | 2009 |
PEGylated lactoferrin enhances its hepatoprotective effects on acute liver injury induced by D-galactosamine and lipopolysaccharide in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cytokines; Disease Models, Animal; Galactosamine; Histocytochemistry; Lactoferrin; Lipopolysaccharides; Liver Failure, Acute; Male; Nitric Oxide; Pilot Projects; Polyethylene Glycols; Rats; Rats, Wistar | 2010 |
Tetrandrine attenuates lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine-sensitized mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Benzimidazoles; Benzylisoquinolines; Blotting, Western; Caspase 3; Galactosamine; Hepatocytes; Hypersensitivity; Lipopolysaccharides; Liver; Liver Failure, Acute; Liver Function Tests; Mice; Mice, Inbred BALB C; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; Survival; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2010 |
A novel scoring system for prognostic prediction in d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure BALB/c mice.
Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Logistic Models; Male; Metabolomics; Mice; Mice, Inbred BALB C; Models, Statistical; Phosphates; Predictive Value of Tests; Prognosis; Ribitol; Urea | 2009 |
Genipin protects lipopolysaccharide-induced apoptotic liver damage in D-galactosamine-sensitized mice.
Topics: Animals; Apoptosis; Caspases; Cell Nucleus; Cytochromes c; Cytosol; Galactosamine; Gene Expression Regulation; Glutathione; I-kappa B Proteins; Iridoid Glycosides; Iridoids; Lipid Peroxidation; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred ICR; NF-KappaB Inhibitor alpha; Oxidative Stress; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-jun; TNF Receptor-Associated Death Domain Protein; Transaminases; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2010 |
[The approaches for making acute-on-chronic liver failure in rat].
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Disease Models, Animal; Galactosamine; Humans; Lipopolysaccharides; Liver Failure, Acute; Male; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Tumour necrosis factor-alpha affects blood-brain barrier permeability and tight junction-associated occludin in acute liver failure.
Topics: Analysis of Variance; Animals; Apoptosis; Blood Chemical Analysis; Blood-Brain Barrier; Blotting, Western; Capillary Permeability; Disease Models, Animal; DNA Primers; Galactosamine; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Liver Failure, Acute; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Occludin; Reverse Transcriptase Polymerase Chain Reaction; Tight Junctions; Tumor Necrosis Factor-alpha | 2010 |
Salvage effect of E5564, Toll-like receptor 4 antagonist on d-galactosamine and lipopolysaccharide-induced acute liver failure in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Biomarkers; Disease Models, Animal; Galactosamine; Injections, Intravenous; Lipid A; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Rats; Rats, Wistar; Time Factors; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2010 |
Effects of intestinal intervention on bacterial translocation in a rat model of acute liver failure in vivo.
Topics: Animals; Bacterial Translocation; Bentonite; Cytokines; Disease Models, Animal; Electrophoresis, Agar Gel; Endotoxins; Escherichia coli; Flow Cytometry; Galactosamine; Gastrointestinal Agents; Green Fluorescent Proteins; Intestines; Lactulose; Liver; Liver Failure, Acute; Lymph Nodes; Male; Microscopy, Confocal; Rats; Rats, Sprague-Dawley; Silicates; Spleen; Toll-Like Receptor 4 | 2010 |
[The role of miRNA-122 expression during the acute liver failure in mice induced by D-GalN/LPS].
Topics: Animals; Galactosamine; Interleukin-6; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Tumor Necrosis Factor-alpha | 2010 |
The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Caspase 3; Drugs, Chinese Herbal; Galactosamine; Glutathione; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Ornithogalum; Oxidative Stress; Phytotherapy; Protective Agents; Saponins; Survival Rate; Tumor Necrosis Factor-alpha | 2010 |
Hepatoprotective effects of Sedum sarmentosum on D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; DNA Fragmentation; Down-Regulation; Galactosamine; Glucose; Hepatocytes; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Nitriles; Plant Extracts; Sedum; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2010 |
[Effects of neurotrophin 3 on interdigestive migrating motor complex in rats with acute liver injury.].
Topics: Animals; Digestion; Female; Galactosamine; Gastrointestinal Motility; Liver Failure, Acute; Male; Myoelectric Complex, Migrating; Neurotrophin 3; Random Allocation; Rats; Rats, Sprague-Dawley | 2010 |
Brain region-selective mechanisms contribute to the progression of cerebral alterations in acute liver failure in rats.
Topics: Ammonia; Animals; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Cerebellum; Cerebrum; Encephalocele; Galactosamine; Glutamine; Intracranial Hypertension; Lactic Acid; Liver Failure, Acute; Male; Rats; Rats, Wistar | 2011 |
Protective effect of Acanthopanax gracilistylus-extracted Acankoreanogenin A on mice with fulminant hepatitis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Drugs, Chinese Herbal; Eleutherococcus; Female; Galactosamine; HMGB1 Protein; Interleukin-1beta; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Tumor Necrosis Factor-alpha | 2011 |
Betulinic acid prevention of d-galactosamine/lipopolysaccharide liver toxicity is triggered by activation of Bcl-2 and antioxidant mechanisms.
Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Betulinic Acid; Caspase 3; Catalase; Disease Models, Animal; Galactosamine; Glutathione; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Liver Failure, Acute; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Survival Analysis; Triterpenes; Up-Regulation | 2011 |
Transplantation of microencapsulated umbilical-cord-blood-derived hepatic-like cells for treatment of hepatic failure.
Topics: Animals; Antigens, CD34; Cell Differentiation; Cell- and Tissue-Based Therapy; Cells, Cultured; Cord Blood Stem Cell Transplantation; Drug Compounding; Fetal Blood; Fibroblast Growth Factor 4; Galactosamine; Hepatocyte Growth Factor; Hepatocytes; Humans; Liver Failure, Acute; Models, Animal; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2011 |
Bioartificial liver system based on choanoid fluidized bed bioreactor improve the survival time of fulminant hepatic failure pigs.
Topics: Alginates; Analysis of Variance; Animals; Bioreactors; Feasibility Studies; Galactosamine; Glucuronic Acid; Hepatocytes; Hexuronic Acids; Kaplan-Meier Estimate; Liver Failure, Acute; Liver, Artificial; Male; Swine; Swine, Miniature | 2011 |
Erythropoietin increases survival and attenuates fulminant hepatic failure injury induced by D-galactosamine/lipopolysaccharide in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Disease Models, Animal; Erythropoietin; Galactosamine; Humans; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Kaplan-Meier Estimate; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; NF-kappa B; Recombinant Proteins; Tumor Necrosis Factor-alpha | 2011 |
A glutamine synthetase inhibitor increases survival and decreases cytokine response in a mouse model of acute liver failure.
Topics: Animals; Apoptosis; Cells, Cultured; Cytokines; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Galactosamine; Glutamate-Ammonia Ligase; Inflammation Mediators; Interferon-gamma; Lipopolysaccharides; Liver; Liver Failure, Acute; Macrophages, Peritoneal; Male; Methionine Sulfoximine; Mice; STAT1 Transcription Factor; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
Dual endothelin-converting enzyme/neutral endopeptidase blockade in rats with D-galactosamine-induced liver failure.
Topics: Animals; Aspartic Acid Endopeptidases; Endothelin-1; Endothelin-Converting Enzymes; Galactosamine; Liver Failure, Acute; Male; Metalloendopeptidases; Neprilysin; Protease Inhibitors; Rats; Rats, Sprague-Dawley | 2011 |
The influence of membrane molecular weight cutoff on a novel bioartificial liver.
Topics: Animals; Bioreactors; Cell Survival; Coculture Techniques; Disease Models, Animal; Dogs; Equipment Design; Galactosamine; Hemodynamics; Hepatocytes; Immunity, Humoral; Liver Failure, Acute; Liver, Artificial; Membranes, Artificial; Mesenchymal Stem Cells; Molecular Weight; Swine | 2012 |
Hepatoprotective effects of IL-22 on fulminant hepatic failure induced by d-galactosamine and lipopolysaccharide in mice.
Topics: Alanine Transaminase; Animals; Base Sequence; bcl-X Protein; Bilirubin; Caspase 3; DNA Primers; DNA-(Apurinic or Apyrimidinic Site) Lyase; Galactosamine; Glutathione; Heme Oxygenase-1; Interleukin-1; Interleukin-22; Interleukins; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Phosphorylation; Recombinant Proteins; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2011 |
Protective effects of luteolin against apoptotic liver damage induced by D-galactosamine/lipopolysaccharide in mice.
Topics: Animals; Apoptosis; Cirsium; Galactosamine; Injections, Intraperitoneal; Liver; Liver Failure, Acute; Luteolin; Male; Mice; Mice, Inbred ICR; Molecular Structure; Receptors, Tumor Necrosis Factor; Transaminases; Tumor Necrosis Factor-alpha | 2011 |
Protective effects of ulinastatin on acute liver failure induced by lipopolysaccharide/D-galactosamine.
Topics: Animals; Caspase 3; Galactosamine; Glycoproteins; Interleukin-6; Liver; Liver Failure, Acute; Male; Malondialdehyde; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Trypsin Inhibitors; Tumor Necrosis Factor-alpha | 2012 |
Complement and the alternative pathway play an important role in LPS/D-GalN-induced fulminant hepatic failure.
Topics: Animals; Complement C3; Complement Membrane Attack Complex; Disease Models, Animal; Drug Combinations; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Anaphylatoxin C5a; Receptors, Complement; Signal Transduction; Survival Rate | 2011 |
Fulminant liver failure models with subsequent encephalopathy in the mouse.
Topics: Animals; Azo Compounds; Disease Models, Animal; Galactosamine; Hepatic Encephalopathy; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Prognosis; Survival Rate; Treatment Outcome; Tumor Necrosis Factor-alpha | 2011 |
A novel small molecule, (E)-5-(2,4-di-tert-butyl-6-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)-5'-methyl-7,7'-dimethoxy-4,4'-bibenzo[d][1,3]dioxole-5,5'-dicarboxylate (7k), alleviates the development of D-galactosamine/lipopolysaccharide-induced acute
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Migration Inhibition; Cell Movement; Cytokines; Dioxoles; Down-Regulation; Female; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Macrophages; Mice; Mice, Inbred BALB C; Thiazolidines | 2012 |
The regulatory role of microRNA-1187 in TNF-α-mediated hepatocyte apoptosis in acute liver failure.
Topics: Animals; Apoptosis; Caspase 8; Down-Regulation; Galactosamine; Hepatocytes; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Real-Time Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Up-Regulation | 2012 |
Gene transfer of c-met confers protection against D-galactosamine/lipopolysaccharide-induced acute liver failure.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Cricetinae; Cricetulus; Female; Galactosamine; Genetic Therapy; Hepatectomy; Hepatocyte Growth Factor; Hepatocytes; Lipopolysaccharides; Liver Failure, Acute; Liver Regeneration; Ovary; Proto-Oncogene Proteins c-met; Rats; Rats, Wistar; Transfection | 2012 |
Reduced hepatic injury in Toll-like receptor 4-deficient mice following D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure.
Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Down-Regulation; Galactosamine; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Phosphorylation; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2012 |
Transplantation of co-microencapsulated hepatocytes and HUVECs for treatment of fulminant hepatic failure.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Cell Survival; Cells, Cultured; Disease Models, Animal; Galactosamine; Graft Rejection; Graft Survival; Hepatocytes; Human Umbilical Vein Endothelial Cells; Humans; Liver; Liver Failure, Acute; Rats; Rats, Sprague-Dawley; Serum Albumin; Time Factors | 2012 |
Hepatoprotective effect and mechanistic insights of deoxyelephantopin, a phyto-sesquiterpene lactone, against fulminant hepatitis.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cyclooxygenase 2; Disease Models, Animal; Galactosamine; Gene Expression Regulation; Heme Oxygenase-1; Hepatitis; Interleukin-6; Lactones; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 8; NF-kappa B; Phosphorylation; Sesquiterpenes; STAT3 Transcription Factor; Transaminases; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2013 |
Human liver stem cells improve liver injury in a model of fulminant liver failure.
Topics: Adult Stem Cells; Animals; Apoptosis; Biomarkers; Chemical and Drug Induced Liver Injury; Culture Media, Conditioned; Galactosamine; Humans; Lipopolysaccharides; Liver; Liver Failure, Acute; Liver Regeneration; Male; Mice; Mice, SCID; Multipotent Stem Cells; Necrosis | 2013 |
Evaluation of a novel hybrid bioartificial liver based on a multi-layer flat-plate bioreactor.
Topics: Animals; Antibodies, Heterophile; Bioreactors; Coculture Techniques; Dogs; Endogenous Retroviruses; Galactosamine; Liver Failure, Acute; Liver, Artificial; Organ Culture Techniques; Prothrombin Time; RNA; RNA-Directed DNA Polymerase; Swine; Time Factors | 2012 |
Ron receptor-dependent gene regulation in a mouse model of endotoxin-induced acute liver failure.
Topics: Animals; Apoptosis; Blotting, Western; Cells, Cultured; Cytokines; Disease Models, Animal; Disease Progression; Galactosamine; Gene Expression Profiling; Gene Expression Regulation; Immunohistochemistry; Inflammation Mediators; Janus Kinases; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Receptor Protein-Tyrosine Kinases; Signal Transduction; STAT Transcription Factors; Suppressor of Cytokine Signaling Proteins; Time Factors | 2012 |
Inhibition of glycogen synthase kinase 3β ameliorates D-GalN/LPS-induced liver injury by reducing endoplasmic reticulum stress-triggered apoptosis.
Topics: Animals; Apoptosis; Caspase 12; Disease Models, Animal; Endoplasmic Reticulum Stress; Enzyme Activation; Enzyme Inhibitors; Galactosamine; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Maleimides; Mice; Mitogen-Activated Protein Kinase Kinases; Signal Transduction; Toll-Like Receptor 4; Transaminases; Transcription Factor CHOP | 2012 |
Inhibiting the expression of hepatocyte nuclear factor 4 alpha attenuates lipopolysaccharide/D-galactosamine-induced fulminant hepatic failure in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; Galactosamine; Hepatocyte Nuclear Factor 4; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Plasmids; RNA, Messenger; RNA, Small Interfering; Survival Rate; Transfection; Tumor Necrosis Factor-alpha | 2012 |
Synergistic effects of antibodies against high-mobility group box 1 and tumor necrosis factor-α antibodies on D-(+)-galactosamine hydrochloride/lipopolysaccharide-induced acute liver failure.
Topics: Alanine Transaminase; Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Chemical and Drug Induced Liver Injury; Drug Synergism; Female; Galactosamine; HMGB1 Protein; Immunohistochemistry; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Necrosis; Nitric Oxide Synthase Type II; Protein Interaction Mapping; Tumor Necrosis Factor-alpha | 2013 |
Hepatoprotective effects of cathepsin B inhibitor on acute hepatic failure induced by lipopolysaccharide/D-galactosamine in mice.
Topics: Animals; Apoptosis; Caspases; Cathepsin B; Cysteine Proteinase Inhibitors; Cytochromes c; Dipeptides; Galactosamine; In Situ Nick-End Labeling; Injections, Intraperitoneal; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Survival Rate; Transaminases; Tumor Necrosis Factor-alpha | 2013 |
Preclinical evaluation of the Excorp Medical, Inc, Bioartificial Liver Support System.
Topics: Animals; Dogs; Galactosamine; Liver Failure, Acute; Liver, Artificial; Male; Models, Animal; Survival Analysis; Time Factors | 2002 |
Deletion of the Ron receptor tyrosine kinase domain in mice provides protection from endotoxin-induced acute liver failure.
Topics: Animals; Apoptosis; Cytokines; Galactosamine; Gene Deletion; Kupffer Cells; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Knockout; Phenotype; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface | 2002 |
Hepatocyte isolation and transplantation in the pig.
Topics: Animals; Cell Separation; Cell Survival; Cell Transplantation; Collagenases; Disease Models, Animal; Endopeptidases; Galactosamine; Hepatocytes; Liver Diseases; Liver Failure, Acute; Liver Transplantation; Male; Perfusion; Survival Rate; Sus scrofa; Transplantation, Heterologous; Treatment Outcome | 2003 |
D-galactosamine based canine acute liver failure model.
Topics: Animals; Disease Models, Animal; Dogs; Galactosamine; Liver; Liver Failure, Acute; Male; Survival Analysis | 2002 |
Protection against liver injury by PGE1 or anti-TNF-alpha is associated with a reduction of TNF-R1 expression in hepatocytes.
Topics: Alanine Transaminase; Alprostadil; Animals; Biomarkers; Disease Models, Animal; Galactosamine; Hepatocytes; Immunohistochemistry; Liver; Liver Failure, Acute; Male; Necrosis; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2003 |
Microencapsulated hepatocytes and islets as in vivo bioartificial liver support system.
Topics: Animals; Bioartificial Organs; Capsules; Cell Transplantation; Galactosamine; Hepatocytes; Islets of Langerhans Transplantation; Liver Failure, Acute; Male; Mice; Mice, Inbred Strains; Rats; Rats, Wistar; Stereoisomerism | 2004 |
Changes of gut flora and endotoxin in rats with D-galactosamine-induced acute liver failure.
Topics: Animals; Colony Count, Microbial; Endotoxins; Enterobacteriaceae; Galactosamine; Intestinal Mucosa; Intestines; Lactobacillus; Liver Failure, Acute; Male; Portal Vein; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2004 |
[The experimental study on the expression of toll-like receptor 2 in fulminant hepatic failure].
Topics: Animals; Galactosamine; Interferon-gamma; Interleukin-18; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; RNA, Messenger; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha | 2004 |
[Protective effect of SNMC on mice with fulminant liver failure].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Galactosamine; Glycyrrhizic Acid; Lipopolysaccharides; Liver Failure, Acute; Male; Mice | 2005 |
[Tumor necrosis factor alpha and enterocyte apoptosis in mice with fulminant hepatic failure].
Topics: Animals; Apoptosis; Enterocytes; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Tumor Necrosis Factor-alpha | 2005 |
Adenoviral gene transfer of ABIN-1 protects mice from TNF/galactosamine-induced acute liver failure and lethality.
Topics: Adenoviridae; Animals; Apoptosis; Cells, Cultured; DNA-Binding Proteins; Female; Galactosamine; Gene Transfer Techniques; Genetic Therapy; Hepatocytes; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2005 |
[Effect of diazepam and modafinil on acute hepatic failure in mice].
Topics: Animals; Benzhydryl Compounds; Diazepam; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Modafinil; Random Allocation | 2005 |
[Establishment of a porcine model of acute hepatic failure by intraportal injection of D-galactosamine and lipopolysaccharide].
Topics: Animals; Disease Models, Animal; Female; Galactosamine; Injections, Intravenous; Lipopolysaccharides; Liver Failure, Acute; Portal Vein; Random Allocation; Swine | 2005 |
[Caspase-12 expression and activation in the pathogenesis of acute hepatic failure induced by lipopolysaccharide and D-galactosamine].
Topics: Animals; Apoptosis; Caspase 12; Endoplasmic Reticulum Chaperone BiP; Galactosamine; Hepatocytes; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Random Allocation; RNA, Messenger | 2005 |
Salvage effect of the vascular endothelial growth factor on chemically induced acute severe liver injury in rats.
Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Follow-Up Studies; Galactosamine; Hepatocytes; Immunohistochemistry; Lipopolysaccharides; Liver Failure, Acute; Liver Regeneration; Male; Rats; Salvage Therapy; Survival Rate; Treatment Outcome; Vascular Endothelial Growth Factor A | 2006 |
Evaluation of a bioartificial liver based on a nonwoven fabric bioreactor with porcine hepatocytes in pigs.
Topics: Animals; Bioreactors; Disease Models, Animal; Equipment Design; Galactosamine; Hemoperfusion; Hepatocytes; Liver Failure, Acute; Liver, Artificial; Male; Swine; Swine, Miniature; Textiles; Treatment Outcome | 2006 |
Suramin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of NF-kappaB activity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Line; Cytokines; Galactosamine; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Suramin; Survival Rate; Tumor Necrosis Factor-alpha | 2006 |
Protective effect of bicyclol on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in mice.
Topics: Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Blood Coagulation; Dose-Response Relationship, Drug; Galactosamine; Gene Expression Regulation; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-10; Lipopolysaccharide Receptors; Lipopolysaccharides; Liver; Liver Failure, Acute; Lymphocyte Function-Associated Antigen-1; Male; Mice; Mice, Inbred ICR; RNA, Messenger; Time Factors; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2006 |
TIMP-1/MMP-9 imbalance in brain edema in rats with fulminant hepatic failure.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Collagenases; Dipeptides; Disease Models, Animal; Enzyme Inhibitors; Enzyme Precursors; Galactosamine; Injections, Intraperitoneal; Liver Failure, Acute; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1 | 2006 |
Fructose 1,6-bisphosphate prevented endotoxemia, macrophage activation, and liver injury induced by D-galactosamine in rats.
Topics: Analysis of Variance; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fructosediphosphates; Galactosamine; Hepatocytes; Histamine Release; Immunologic Factors; Inflammation; Kupffer Cells; Liver Failure, Acute; Macrophage Activation; Potassium Channels; Rats; Rats, Sprague-Dawley; Sepsis; Tumor Necrosis Factor-alpha | 2006 |
[Protective effects of granulocyte colony-stimulating factor on acute hepatic failure induced by D-galactosamine/lipopolysaccharide in mice].
Topics: Animals; Galactosamine; Granulocyte Colony-Stimulating Factor; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Protective Agents; Random Allocation; Recombinant Proteins | 2006 |
[Role of hepatocellular apoptosis and mechanisms of liver injury in lipopolysaccharide-induced acute liver failure in D-galactosamine-sensitized rats].
Topics: Animals; Apoptosis; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Male; Random Allocation; Rats; Rats, Wistar | 2006 |
A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats.
Topics: Adenoviridae; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Line, Transformed; Combined Modality Therapy; Disease Models, Animal; Extracorporeal Circulation; Female; Galactosamine; Genetic Therapy; Hepatocytes; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Interleukin-6; Liver; Liver Failure, Acute; Liver, Artificial; Male; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Survival Rate; Transfection; U937 Cells | 2007 |
Characterization of the molecular mechanisms involved in the increased insulin secretion in rats with acute liver failure.
Topics: Alanine Transaminase; Animals; Blood Glucose; Disease Models, Animal; Galactosamine; Hyperinsulinism; Insulin; Insulin Secretion; Islets of Langerhans; Liver Failure, Acute; Male; Organ Size; Polypyrimidine Tract-Binding Protein; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2007 |
Carbon monoxide inhalation rescues mice from fulminant hepatitis through improving hepatic energy metabolism.
Topics: Animals; Antimetabolites; Apoptosis; Carbon Monoxide; Chemical and Drug Induced Liver Injury; Energy Metabolism; Galactosamine; Guanylate Cyclase; Heme Oxygenase-1; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Tumor Necrosis Factor-alpha | 2007 |
Metabolic profiling analysis of a D-galactosamine/lipopolysaccharide-induced mouse model of fulminant hepatic failure.
Topics: Animals; Blood Glucose; Disease Models, Animal; Galactosamine; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glycolysis; Hydroxyindoleacetic Acid; Lipopolysaccharides; Liver Failure, Acute; Mice; Phosphates; Serum | 2007 |
Type I inositol 1, 4, 5-triphosphate receptors increase in kidney of mice with fulminant hepatic failure.
Topics: Animals; Calcium Channels; Disease Models, Animal; Disease Progression; Galactosamine; Glomerular Mesangium; Hepatorenal Syndrome; Inositol 1,4,5-Trisphosphate Receptors; Kidney; Lipopolysaccharides; Liver Failure, Acute; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Up-Regulation | 2007 |
Attenuation of inflammation and apoptosis by pre- and posttreatment of darbepoetin-alpha in acute liver failure of mice.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Cytokines; Darbepoetin alfa; Erythropoietin; Galactosamine; Hematinics; Inflammation; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Proliferating Cell Nuclear Antigen | 2007 |
Galactosamine-induced fulminant liver failure--observation in a porcine model.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Costs; Galactosamine; Liver Failure, Acute; Swine | 2002 |
[Effect of Suanzaoren decoction on acute hepatic failure in mice].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cytokines; Drug Combinations; Drugs, Chinese Herbal; Free Radicals; Galactosamine; Glutathione; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Malondialdehyde; Mice; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Superoxide Dismutase | 2007 |
Endotoxin- and D-galactosamine-induced liver injury improved by the administration of Lactobacillus, Bifidobacterium and blueberry.
Topics: Animals; Bifidobacterium; Blueberry Plants; Cecum; Dietary Supplements; Disease Models, Animal; Endotoxins; Galactosamine; Inflammation; Lactobacillus plantarum; Liver Failure, Acute; Probiotics; Rats | 2007 |
Methylprednisolone injection via the portal vein suppresses inflammation in acute liver failure induced in rats by lipopolysaccharide and d-galactosamine.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Galactosamine; Injections, Intravenous; Interferon-gamma; Lipopolysaccharides; Liver Failure, Acute; Male; Methylprednisolone Hemisuccinate; Portal Vein; Rats; Rats, Wistar; Survival Rate; Tumor Necrosis Factor-alpha | 2007 |
Early growth response-1 contributes to galactosamine/lipopolysaccharide-induced acute liver injury in mice.
Topics: Animals; Disease Models, Animal; Early Growth Response Protein 1; Female; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred C57BL | 2007 |
A role of cell apoptosis in lipopolysaccharide (LPS)-induced nonlethal liver injury in D-galactosamine (D-GalN)-sensitized rats.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Apoptosis; Aspartate Aminotransferases; Bilirubin; Caspases; Galactosamine; In Situ Nick-End Labeling; Lipopolysaccharides; Liver Failure, Acute; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Protective effect of neutrophil elastase inhibitor (FR136706) in lethal acute liver failure induced by D-galactosamine and lipopolysaccharide in rats.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Cytokines; Disease Models, Animal; Galactosamine; L-Lactate Dehydrogenase; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Neutrophil Infiltration; NF-kappa B; Nitric Oxide Synthase Type II; Proteinase Inhibitory Proteins, Secretory; Pyrroles; Rats; Rats, Sprague-Dawley | 2008 |
[Establishment of a D-galactosamine/lipopolysaccharide induced acute-on-chronic liver failure model in rats].
Topics: Animals; Disease Models, Animal; Female; Galactosamine; Humans; Lipopolysaccharides; Liver Failure, Acute; Rats; Rats, Wistar; Serum Albumin | 2007 |
Intracranial pressure observations in a canine model of acute liver failure supported by a bioartificial liver support system.
Topics: Animals; Disease Models, Animal; Dogs; Galactosamine; Intracranial Hypertension; Intracranial Pressure; Liver Failure, Acute; Liver, Artificial; Probability; Random Allocation; Reference Values; Retrospective Studies; Risk Factors; Sensitivity and Specificity; Statistics, Nonparametric; Survival Rate | 2007 |
Expression of Toll-like receptor 4 in various organs in rats with D-galactosamine-induced acute hepatic failure.
Topics: Animals; Disease Models, Animal; Endotoxins; Galactosamine; Immunity, Innate; Lipopolysaccharide Receptors; Liver; Liver Failure, Acute; Lung; Male; Rats; Rats, Wistar; RNA, Messenger; Spleen; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2008 |
Differential effects of pyrrolidine dithiocarbamate on TNF-alpha-mediated liver injury in two different models of fulminant hepatitis.
Topics: Animals; Antioxidants; Disease Models, Animal; Female; Galactosamine; Glutathione; Hepatitis; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Mice; Mice, Inbred Strains; Mycobacterium bovis; NF-kappa B; Nitric Oxide; Pyrrolidines; Thiocarbamates; Tumor Necrosis Factor-alpha | 2008 |
A diterpenoid acanthoic acid from Acanthopanax koreanum protects against D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure in mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Diterpenes; DNA Fragmentation; Eleutherococcus; Galactosamine; In Situ Nick-End Labeling; Lipopolysaccharides; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Plant Roots; Tumor Necrosis Factor-alpha | 2008 |
Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blotting, Western; Chromatography, High Pressure Liquid; Cysteine; Disease Models, Animal; Galactosamine; Glutathione Transferase; Immunohistochemistry; Isoenzymes; Leukotriene C4; Leukotrienes; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Up-Regulation | 2008 |
Brain somatostatin receptors in a rat model of acute liver failure.
Topics: Adenylyl Cyclases; Animals; Brain; Disease Models, Animal; Frontal Lobe; Galactosamine; Hippocampus; Injections, Intraperitoneal; Kinetics; Liver Failure, Acute; Rats; Rats, Wistar; Receptors, Somatostatin | 1995 |
[Influence of splenectomy on drug therapy for acute liver failure induced by D-galactosamine and lipopolysaccharide in rats].
Topics: Animals; Bucladesine; Galactosamine; Lipopolysaccharides; Liver Failure, Acute; Male; Picibanil; Rats; Rats, Wistar; Spleen; Splenectomy | 1995 |
Encapsulated hepatocyte transplantation for the treatment of D-galactosamine-induced acute hepatic failure in rats.
Topics: Animals; Aspartate Aminotransferases; Galactosamine; Liver Failure, Acute; Liver Transplantation; Male; Mononuclear Phagocyte System; Phagocytosis; Rats; Rats, Wistar; Survival Rate | 1993 |
Bacterial translocation in acute liver injury induced by D-galactosamine.
Topics: Analysis of Variance; Animals; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Translocation; Cecum; Galactosamine; Hepatectomy; Intestinal Mucosa; Intestine, Small; Liver Failure, Acute; Lung; Permeability; Portal Pressure; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1996 |
Cotransplantation of microencapsulated hepatocytes and islets for acute hepatic failure in rats.
Topics: Animals; Capsules; Cell Separation; Galactosamine; Islets of Langerhans Transplantation; Liver; Liver Failure, Acute; Liver Transplantation; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar; Survival Rate; Transplantation, Homologous | 1996 |
Effect of alanine on D-galactosamine-induced acute liver failure in rats.
Topics: Adenosine Triphosphate; Alanine; Animals; DNA; Galactosamine; Ketone Bodies; Liver; Liver Failure, Acute; Male; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1996 |
Ultrastructural study of development of hepatic necrosis induced by TNF-alpha and D-galactosamine.
Topics: Animals; Galactosamine; Kupffer Cells; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred ICR; Microscopy, Electron; Microscopy, Electron, Scanning; Necrosis; Time Factors; Tumor Necrosis Factor-alpha | 1998 |
Does hepatocyte transplantation in a chemically induced acute hepatic failure make sense?
Topics: Animals; Cell Transplantation; Galactosamine; Liver; Liver Failure, Acute; Male; Rats; Rats, Wistar; Spleen; Time Factors; Transplantation, Heterotopic | 1998 |
Glutathione peroxidase-deficient mice are more susceptible to neutrophil-mediated hepatic parenchymal cell injury during endotoxemia: importance of an intracellular oxidant stress.
Topics: Animals; Apoptosis; Endotoxemia; Endotoxins; Galactosamine; Glutathione Disulfide; Glutathione Peroxidase; Intercellular Adhesion Molecule-1; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C3H; Neutrophils; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 1999 |
Integration and proliferation of transplanted cells in hepatic parenchyma following D-galactosamine-induced acute injury in F344 rats.
Topics: Animals; Cell Division; Cell Movement; Cell Survival; Cell Transplantation; Galactosamine; Graft Survival; Liver; Liver Failure, Acute; Male; Rats; Rats, Inbred F344 | 2000 |
TNF-alpha dependent production of inducible nitric oxide is involved in PGE(1) protection against acute liver injury.
Topics: Alanine Transaminase; Alprostadil; Animals; Antibodies; Galactosamine; Liver Failure, Acute; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2000 |
Isolation and characterization of a novel liver-specific gene, hepassocin, upregulated during liver regeneration.
Topics: Amino Acid Sequence; Animals; Base Sequence; DNA; DNA, Complementary; Galactosamine; Gene Expression Regulation; Liver; Liver Failure, Acute; Liver Regeneration; Male; Molecular Sequence Data; Neoplasm Proteins; Proteins; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger; Transfection; Up-Regulation | 2000 |
Multisorbent plasma perfusion in fulminant hepatic failure: effects of duration and frequency of treatment in rats with grade III hepatic coma.
Topics: Animals; Disease Models, Animal; Female; Galactosamine; Hepatic Encephalopathy; Liver Failure, Acute; Liver Regeneration; Liver, Artificial; Perfusion; Plasma; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Survival Rate; Treatment Outcome | 2001 |
[The protective effects of thalidomide on acute liver failure].
Topics: Animals; Galactosamine; Immunosuppressive Agents; Lipopolysaccharides; Liver Failure, Acute; Male; Rats; Rats, Wistar; RNA, Messenger; Thalidomide; Tumor Necrosis Factor-alpha | 1999 |
Protective effect of pretreatment with low-dose lipopolysaccharide on D-galactosamine-induced acute liver failure.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Enzyme Inhibitors; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred F344 | 2002 |
Effectivity and safety of mannitol treatment for acute hepatic failure in rats.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Body Water; Brain; Brain Edema; Disease Models, Animal; Galactosamine; Liver Failure, Acute; Male; Mannitol; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Survival Rate | 1992 |