Page last updated: 2024-08-21

galactitol and Galactosemias

galactitol has been researched along with Galactosemias in 90 studies

Research

Studies (90)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (30.00)	18.7374
1990's	28 (31.11)	18.2507
2000's	27 (30.00)	29.6817
2010's	7 (7.78)	24.3611
2020's	1 (1.11)	2.80

Authors

Authors	Studies
Arai-Ichinoi, N; Kikuchi, A; Kure, S; Wada, Y	1
Blaga, L; Căinap, SS; Deleanu, C; Fufezan, O; Grama, A; Militaru, M; Nicolescu, A; Pop, I; Pop, TL; Sîrbe, C; Tita, G; Vințan, MA; Vulturar, R	1
Bernardi, B; Colafati, GS; Dionisi-Vici, C; Martinelli, D; Napolitano, A	1
Boers, GH; Bosch, AM; Guion, N; Hammen, HW; Janssen, M; Kamalanathan, L; Schadewaldt, P; Schwarz, M; Wendel, U	1
Day-Salvatore, DL; Ficicioglu, C; Forbes, BJ; Gallagher, PR; Hussa, C; Mattie, A; Thomas, N; Yager, C	1
Clark, A; Geoghegan, O; Hendroff, U; Hughes, J; Lambert, D; Monavari, A; Rogers, Y; Ryan, S; Treacy, EP; Twomey, E	1
Elsas, LJ; Lai, K; Wierenga, KJ	1
Fernhoff, PM	1
Ficicioglu, C; Gallagher, PR; Hussa, C; Thomas, N; Yager, C	1
Hennermann, JB; Klein, J; Mönch, E; Schadewaldt, P; Shin, YS; Vetter, B	1
Joost, K; Krabbi, K; Õunap, K; Uudelepp, ML; Zordania, R	1
Asres, K; Rao, AR; Swetha, E; Veeresham, C	1
Elsas, LJ; Kennedy, MJ; Singh, RH; Webb, AL	1
Chan, YS; Chung, SK; Chung, SS; Fu, DT; Leung, S; Song, Z	1
EGAN, TJ; PITTMAN, TA; WELLS, WW	1
EGAN, TJ; PITTMAN, TA; WELLS, HJ; WELLS, WW	1
Hammen, HW; Kamalanathan, L; Killius, S; Schadewaldt, P; Strassburger, K; Wendel, U	1
Hammen, HW; Kamalanathan, L; Schadewaldt, P; Wendel, U	2
Chen, J; Reynolds, R; Segal, S; Yager, CT	1
Battelino, T; Gobec, L; Karas, N; Lukac-Bajalo, J; Mlinar, B; Pfeifer, V	1
Hammen, HW; Kamalanathan, L; Schadewaldt, P; Stolpmann, S; Wendel, U	1
Behrakis, P; Marinou, K; Schulpis, KH; Tsakiris, S	1
Bakker, HD; Bosch, AM; Wanders, RJ; Wenniger-Prick, LJ; Wijburg, FA	1
Antshel, KM; Epstein, IO; Waisbren, SE	1
Behrakis, P; Marinou, K; Schulpis, KH; Tsakiris, S; Tsopanakis, C	2
Ficicioglu, C; Segal, S; Yager, C	1
Segal, S; Wehrli, S; Yager, C	1
Arita, F; Costa, MO; Lacerda, MT; Leite, CC; Otaduy, MC; Prado, E; Rosemberg, S	1
Brunetti-Pierri, N; Craigen, WJ; Opekun, AR	1
Nasiell, J; Ohlsson, A; von Döbeln, U	1
Cuthbert, C; Elsas, L; Klapper, H	1
Allen, JT; Gillett, M; Holton, JB; King, GS; Pettit, BR	1
Jakobs, C; Nyhan, WL; Sweetman, L; Warner, TG	1
Gitzelmann, R; Steinmann, B	1
Allen, JT; Gillett, MG; Holton, JB	1
Julia, C; Kador, PF; Neuenschwander, H; Wyman, M	1
Dorland, B; Jakobs, C; Schweitzer, S	1
Berry, GT	1
Koch, HG; Möller, HE; Schuierer, G; Ullrich, K; Vermathen, P	1
Chung, SK; Chung, SS; Lee, AY	1
Basso, M; Cherian, PV; Hohman, TC; Kamijo, M; Sima, AA	1
Engerman, RL; Kern, TS	4
Hohman, TC; Malamas, MS; Millen, J	1
Monnier, VM; Nagaraj, RH; Ortwerth, BJ; Prabhakaram, M	1
Okamura, R; Taura, T; Teshima, R	1
Brodehl, J; Jakobs, C; Schweitzer, S; Shin, Y	1
Acosta, PB; Berry, GT; Gross, KC; Henstenburg, JA; Mazur, A; Palmieri, M; Reynolds, R; Segal, S	1
Baba, M; Fujimoto, J; Kokai, Y; Nishimura, C; Sugimoto, K; Wada, R; Wong, HG; Yagihashi, S; Yamagishi, S	1
Burgan, J; Faller, A; Obrosova, I; Ostrow, E; Williamson, JR	1
Gupta, SK; Joshi, S; Mathur, P; Tandon, R	1
Allen, J; Green, A; Holton, JB; Hutchesson, AC; Murdoch-Davis, C; Preece, MA; Rylance, G	1
Andrade, J; Eu, JY; Wang, CY	1
Goto, H; Ishiguro, I; Majima, Y; Niwa, T; Ohta, Y; Yamasaki, T	1
Berkowitz, BA; Frank, RN; Hohman, TC; Kern, TS; Kowluru, RA; Prakash, M	1
Bakker, HD; de Jongh, S; IJst, L; Jakobs, C; Vreken, P; Wanders, RJ	1
Berry, GT; Elsas, L; Langley, S; Mazur, A; Muralidharan, K; Ning, C; Palmieri, M; Reynolds, R; Segal, S; Singh, R; Wehrli, S; Yager, C	1
Ali, AH; Devamanoharan, PS; Henein, M; Varma, SD	1
Majima, Y; Niwa, T; Ohta, Y; Yamasaki, T	1
Ning, C; Segal, S	1
Berry, GT; Brooks, DG; Dreha, S; Hunter, JV; Mazur, A; Ning, C; Segal, S; Wang, Z; Zimmerman, RA	1
Chen, J; Reynolds, RA; Segal, S; Yager, CT	1
Aldinger, CE; MacDonald, DP; Peterson, MJ; Sarges, R	2
Ghosh, MN; Parmar, NS	1
Bergren, WR; Donnell, GN; Ng, WG	1
Cameron, NE; Cotter, MA; Cox, D; Robertson, S	1
Baillet, A; Baylocq-Ferrier, D; Pellerin, F; Rakotomanga, S	1
Hayashi, M; Mino, M; Yamazaki, T	1
Cheng, HM; Tsubota, K; Xiong, H; Xiong, J	1
Alloussi, S; Birlouez-Aragon, I	1
Brivet, M; Cheron, G; Lemonnier, A; Migayron, F; Roger, J	1
Brazzell, RK; Chandler, ML; Dickerson, JE; Lou, MF; York, BM	1
Alloussi, S; Birlouez-Aragon, I; Fevrier, C; Papadopoulos, H	1
Brivet, M; Konopka, P; Lemonnier, A; Odievre, M; Raymond, JP	1
Dickerson, JE; Garadi, R; Lou, MF; York, BM	1
Kanbara, M; Miwa, I; Okuda, J; Wakazono, H	1
Bakker, HD; Jakobs, C; Kleijer, WJ; Niermeijer, MF; Przyrembel, H; van Gennip, AH	1
Fujimori, S; Hirata, Y; Okada, K; Segawa, M	1
Bessard, C; Birlouez, I; Dillon, JC; Lestradet, H	1
Máté, M	1
Adrian, J; Kechrid, RM; Poiffait, A	1
Bachmann, C; Schaefer, T; Schwarz, HP	1
Dvornik, D; Gonzalez, R; Greselin, E; Simard-Duquesne, N	1
Dvornik, D; Simard-Duquesne, N	1
Bergren, WR; Donnell, GN; Ng, WG; Roe, TF	1

Reviews

2 review(s) available for galactitol and Galactosemias

Article	Year
Galactose toxicity in animals. IUBMB life, 2009, Volume: 61, Issue:11 Topics: Animals; Galactitol; Galactokinase; Galactose; Galactosemias; Galactosephosphates; Humans; Infant, Newborn; Inositol; Models, Animal; Neonatal Screening; UDPglucose 4-Epimerase; UTP-Hexose-1-Phosphate Uridylyltransferase	2009
The role of polyols in the pathophysiology of hypergalactosemia. European journal of pediatrics, 1995, Volume: 154, Issue:7 Suppl 2 Topics: Animals; Galactitol; Galactosemias; Humans; Inositol	1995

Trials

1 trial(s) available for galactitol and Galactosemias

Article	Year
Verbal dyspraxia and galactosemia. Pediatric research, 2003, Volume: 53, Issue:3 Topics: Adult; Apraxias; Breath Tests; Carbon Dioxide; Carbon Isotopes; Child; Erythrocytes; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Genotype; Humans; Male; Phenotype; Prospective Studies; Reproducibility of Results; Risk Factors; Sensitivity and Specificity	2003

Other Studies

87 other study(ies) available for galactitol and Galactosemias

Article	Year
β-Galactosidase therapy can mitigate blood galactose elevation after an oral lactose load in galactose mutarotase deficiency. Journal of inherited metabolic disease, 2022, Volume: 45, Issue:2 Topics: beta-Galactosidase; Carbohydrate Epimerases; Cataract; Galactitol; Galactose; Galactosemias; Humans; Lactose	2022
Novel Mutation in GALT Gene in Galactosemia Patient with Group B Streptococcus Meningitis and Acute Liver Failure. Medicina (Kaunas, Lithuania), 2019, Apr-04, Volume: 55, Issue:4 Topics: Child, Preschool; Developed Countries; Female; Follow-Up Studies; Galactitol; Galactose; Galactosemias; Humans; Infant, Newborn; Lactose Tolerance Test; Liver Failure, Acute; Magnetic Resonance Spectroscopy; Meningitis, Bacterial; Mutation; Neonatal Screening; Romania; Streptococcal Infections; Streptococcus; UTP-Hexose-1-Phosphate Uridylyltransferase	2019
Teaching NeuroImages: Galactitol peak and fatal cerebral edema in classic galactosemia: Too much sugar in the brain. Neurology, 2016, Jan-19, Volume: 86, Issue:3 Topics: Brain Edema; Fatal Outcome; Female; Galactitol; Galactosemias; Humans; Infant, Newborn; Magnetic Resonance Imaging; Neuroimaging; Neurology	2016
Biochemical monitoring of pregnancy and breast feeding in five patients with classical galactosaemia--and review of the literature. European journal of pediatrics, 2009, Volume: 168, Issue:6 Topics: Adult; Breast Feeding; Cesarean Section; Erythrocytes; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Lactation; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Young Adult	2009
Duarte (DG) galactosemia: a pilot study of biochemical and neurodevelopmental assessment in children detected by newborn screening. Molecular genetics and metabolism, 2008, Volume: 95, Issue:4 Topics: Child; Child Development; Child, Preschool; Female; Galactitol; Galactose; Galactosemias; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Neonatal Screening; Pilot Projects	2008
Outcomes of siblings with classical galactosemia. The Journal of pediatrics, 2009, Volume: 154, Issue:5 Topics: Adolescent; Adult; Birth Order; Brain; Child; Child, Preschool; Diet Records; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Infant; Intelligence Tests; Ireland; Lactose; Language Disorders; Magnetic Resonance Spectroscopy; Male; Neurologic Examination; Patient Compliance; Retrospective Studies; Siblings; Young Adult	2009
Duarte galactosemia: how sweet is it? Clinical chemistry, 2010, Volume: 56, Issue:7 Topics: Child; Child, Preschool; Dietary Carbohydrates; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Infant; Sugar Acids	2010
Monitoring of biochemical status in children with Duarte galactosemia: utility of galactose, galactitol, galactonate, and galactose 1-phosphate. Clinical chemistry, 2010, Volume: 56, Issue:7 Topics: Child; Child, Preschool; Dietary Carbohydrates; Erythrocytes; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Infant; Male; Monitoring, Physiologic; Reference Values; Sugar Acids	2010
Features and outcome of galactokinase deficiency in children diagnosed by newborn screening. Journal of inherited metabolic disease, 2011, Volume: 34, Issue:2 Topics: Bosnia and Herzegovina; Emigration and Immigration; Female; Galactitol; Galactose; Galactosemias; Germany; Homozygote; Humans; Incidence; Infant, Newborn; Male; Mutation; Neonatal Screening; Serbia; Treatment Outcome	2011
Long-term complications in Estonian galactosemia patients with a less strict lactose-free diet and metabolic control. Molecular genetics and metabolism, 2011, Volume: 103, Issue:3 Topics: Adolescent; Child; Diet; Estonia; Female; Galactitol; Galactose; Galactosemias; Genotype; Humans; Lactose; Male; Phenotype; Retrospective Studies	2011
In vitro and in vivo aldose reductase inhibitory activity of standardized extracts and the major constituent of Andrographis paniculata. Phytotherapy research : PTR, 2013, Volume: 27, Issue:3 Topics: Aldehyde Reductase; Andrographis; Animals; Diterpenes; Enzyme Inhibitors; Galactitol; Galactosemias; Kidney; Lens, Crystalline; Male; Plant Extracts; Rats; Rats, Wistar	2013
Transgenic mice overexpressing aldose reductase in Schwann cells show more severe nerve conduction velocity deficit and oxidative stress under hyperglycemic stress. Molecular and cellular neurosciences, 2003, Volume: 23, Issue:4 Topics: Aldehyde Reductase; Animals; Axons; Diabetic Neuropathies; Disease Models, Animal; Down-Regulation; Galactitol; Galactosemias; Glutathione; Hyperglycemia; Mice; Mice, Transgenic; Nerve Fibers, Myelinated; Neural Conduction; Oxidative Stress; Schwann Cells; Stress, Physiological; Up-Regulation	2003
THE ISOLATION AND IDENTIFICATION OF GALACTITOL FROM THE URINE OF PATIENTS WITH GALACTOSEMIA. The Journal of biological chemistry, 1964, Volume: 239 Topics: Alcohols; Blood Chemical Analysis; Body Fluids; Carbohydrate Metabolism; Chromatography; Galactitol; Galactose; Galactosemias; Humans; Infant; Urine	1964
THE ISOLATION AND IDENTIFICATION OF GALACTITOL FROM THE BRAINS OF GALACTOSEMIA PATIENTS. The Journal of biological chemistry, 1965, Volume: 240 Topics: Alcohols; Brain; Brain Chemistry; Carbohydrate Metabolism; Chromatography; Electrophoresis; Galactitol; Galactosemias; Humans; Infant; Inositol; Lipid Metabolism; Spectrum Analysis	1965
Renal excretion of galactose and galactitol in patients with classical galactosaemia, obligate heterozygous parents and healthy subjects. Journal of inherited metabolic disease, 2003, Volume: 26, Issue:5 Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Female; Galactitol; Galactose; Galactosemias; Heterozygote; Humans; Kidney; Male; Middle Aged	2003
Stable-isotope dilution analysis of galactose metabolites in human erythrocytes. Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:24 Topics: Blood Chemical Analysis; Erythrocytes; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Male; Metabolic Clearance Rate; Radioisotope Dilution Technique; Reproducibility of Results; Sensitivity and Specificity	2003
Galactitol and galactonate in red blood cells of galactosemic patients. Molecular genetics and metabolism, 2003, Volume: 80, Issue:3 Topics: Adolescent; Calibration; Carbon Isotopes; Child; Child, Preschool; Erythrocytes; Galactitol; Galactosemias; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Sugar Acids	2003
Mutations in galactose-1-phosphate uridyltransferase gene in patients with idiopathic presenile cataract. Journal of inherited metabolic disease, 2003, Volume: 26, Issue:7 Topics: Adult; Alleles; Cataract; DNA; Female; Galactitol; Galactosemias; Humans; Male; Middle Aged; Mutation; Reverse Transcriptase Polymerase Chain Reaction; UTP-Hexose-1-Phosphate Uridylyltransferase	2003
Age dependence of endogenous galactose formation in Q188R homozygous galactosemic patients. Molecular genetics and metabolism, 2004, Volume: 81, Issue:1 Topics: Adolescent; Adult; Age Factors; Body Height; Body Weight; Carbon Isotopes; Child; Child, Preschool; Galactitol; Galactose; Galactosemias; Humans; Infusion Pumps; Models, Biological; Mutation; Sugar Acids; UTP-Hexose-1-Phosphate Uridylyltransferase	2004
Galactonate determination in urine by stable isotope dilution gas chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Mar-05, Volume: 801, Issue:2 Topics: Adolescent; Adult; Carbon Isotopes; Child; Child, Preschool; Female; Galactitol; Galactose; Galactosemias; Gas Chromatography-Mass Spectrometry; Humans; Indicator Dilution Techniques; Lactones; Male; Quality Control; Sensitivity and Specificity; Sugar Acids	2004
Protective effect of L-cysteine and glutathione on the modulated suckling rat brain Na+, K+, -ATPase and Mg2+ -ATPase activities induced by the in vitro galactosaemia. Pharmacological research, 2004, Volume: 49, Issue:5 Topics: Animals; Animals, Suckling; Antioxidants; Brain; Brain Diseases, Metabolic, Inborn; Ca(2+) Mg(2+)-ATPase; Cysteine; Drug Combinations; Drug Evaluation, Preclinical; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Glutathione; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase	2004
High tolerance for oral galactose in classical galactosaemia: dietary implications. Archives of disease in childhood, 2004, Volume: 89, Issue:11 Topics: Administration, Oral; Adolescent; Drug Tolerance; Female; Fruit; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Male; Vegetables	2004
Cognitive strengths and weaknesses in children and adolescents homozygous for the galactosemia Q188R mutation: a descriptive study. Neuropsychology, 2004, Volume: 18, Issue:4 Topics: Adolescent; Analysis of Variance; Arginine; Case-Control Studies; Child; Cognition; Female; Galactitol; Galactosemias; Galactosephosphates; Glutamine; Homozygote; Humans; Intelligence; Male; Mutation; Neuropsychological Tests; UTP-Hexose-1-Phosphate Uridylyltransferase	2004
Mg2+-ATPase activity in suckling rat brain regions in galactosaemia in vitro. L-Cysteine and glutathione effects. Toxicology in vitro : an international journal published in association with BIBRA, 2005, Volume: 19, Issue:2 Topics: Animals; Animals, Suckling; Antioxidants; Brain; Ca(2+) Mg(2+)-ATPase; Cysteine; Drug Combinations; Enzyme Activation; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Glutathione; Male; Rats; Rats, Wistar	2005
Galactitol and galactonate in red blood cells of children with the Duarte/galactosemia genotype. Molecular genetics and metabolism, 2005, Volume: 84, Issue:2 Topics: Erythrocytes; Galactitol; Galactosemias; Gas Chromatography-Mass Spectrometry; Genotype; Humans; Infant; Infant, Newborn; Sugar Acids	2005
Suckling rat brain regional distribution of Na+,K+-atpase activity in the in vitro galactosaemia: the effect of L-cysteine and glutathione. Metabolic brain disease, 2005, Volume: 20, Issue:1 Topics: Animals; Animals, Suckling; Antioxidants; Brain; Brain Chemistry; Cysteine; Disease Models, Animal; Enzyme Activation; Female; Free Radicals; Galactitol; Galactose; Galactosemias; Galactosephosphates; Glutathione; In Vitro Techniques; Male; Oxidative Stress; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions	2005
Urinary galactitol and galactonate quantified by isotope-dilution gas chromatography-mass spectrometry. Clinica chimica acta; international journal of clinical chemistry, 2006, Volume: 366, Issue:1-2 Topics: Adolescent; Adult; Calibration; Child; Child, Preschool; Galactitol; Galactosemias; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Radioisotope Dilution Technique; Reference Values; Reproducibility of Results; Sugar Acids	2006
Proton MR spectroscopy and imaging of a galactosemic patient before and after dietary treatment. AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:1 Topics: Brain; Brain Chemistry; Female; Galactitol; Galactosemias; Humans; Infant; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy	2006
Two familial cases of high blood galactose of unknown aetiology. Journal of inherited metabolic disease, 2006, Volume: 29, Issue:6 Topics: Carbohydrate Metabolism, Inborn Errors; Cell Membrane; Chromosomes, Human, X; Family Health; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Infant, Newborn; Lactose; Male	2006
Pregnancy and lactation in a woman with classical galactosaemia heterozygous for p.Q188R and p.R333W. Journal of inherited metabolic disease, 2007, Volume: 30, Issue:1 Topics: Adult; Breast Feeding; Female; Galactitol; Galactosemias; Galactosephosphates; Heterozygote; Humans; Pregnancy; Time Factors	2007
Diagnosis of inherited disorders of galactose metabolism. Current protocols in human genetics, 2008, Volume: Chapter 17 Topics: Carbohydrate Metabolism, Inborn Errors; DNA Mutational Analysis; DNA Primers; Galactitol; Galactokinase; Galactose; Galactosemias; Galactosephosphates; Genetics, Medical; Humans; Infant, Newborn; Neonatal Screening; Polymerase Chain Reaction; UDPglucose 4-Epimerase; UTP-Hexose-1-Phosphate Uridylyltransferase	2008
Evidence for galactosaemia in utero. Lancet (London, England), 1980, Mar-15, Volume: 1, Issue:8168 Pt 1 Topics: Clinical Enzyme Tests; Female; Galactitol; Galactosemias; Gestational Age; Humans; Pregnancy; Prenatal Diagnosis	1980
Stable isotope dilution analysis of galactitol in amniotic fluid: an accurate approach to the prenatal diagnosis of galactosemia. Pediatric research, 1984, Volume: 18, Issue:8 Topics: Amniotic Fluid; Female; Galactitol; Galactosemias; Gas Chromatography-Mass Spectrometry; Humans; Inositol; Mannitol; Pregnancy; Prenatal Diagnosis; Sorbitol; Sugar Alcohols; UTP-Hexose-1-Phosphate Uridylyltransferase	1984
Galactosemia: how does long-term treatment change the outcome? Enzyme, 1984, Volume: 32, Issue:1 Topics: Female; Galactitol; Galactokinase; Galactosemias; Galactosephosphates; Humans; Hypogonadism; Male; Prognosis; Time Factors; UTP-Hexose-1-Phosphate Uridylyltransferase	1984
Gas-liquid chromatographic determination of galactitol in amniotic fluid for possible use in prenatal diagnosis of galactosaemia. Clinica chimica acta; international journal of clinical chemistry, 1981, Feb-19, Volume: 110, Issue:1 Topics: Amniotic Fluid; Chromatography, Gas; Clinical Laboratory Techniques; Female; Galactitol; Galactosemias; Genetic Carrier Screening; Homozygote; Humans; Pregnancy; Prenatal Diagnosis; Sugar Alcohols	1981
Endothelial changes in galactose-fed dogs. Current eye research, 1995, Volume: 14, Issue:4 Topics: Animals; Cell Count; Cell Size; Diet; Dogs; Endothelium, Corneal; Galactitol; Galactose; Galactosemias; Male	1995
Galactitol in galactosemia. European journal of pediatrics, 1995, Volume: 154, Issue:7 Suppl 2 Topics: Age Factors; Galactitol; Galactose; Galactosemias; Humans; Infant	1995
In vivo study of brain metabolism in galactosemia by 1H and 31P magnetic resonance spectroscopy. European journal of pediatrics, 1995, Volume: 154, Issue:7 Suppl 2 Topics: Adolescent; Adult; Brain; Female; Galactitol; Galactosemias; Galactosephosphates; Humans; Magnetic Resonance Spectroscopy; Male	1995
Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens. Proceedings of the National Academy of Sciences of the United States of America, 1995, Mar-28, Volume: 92, Issue:7 Topics: Aldehyde Reductase; Animals; Blotting, Southern; Cataract; Crosses, Genetic; Diabetes Mellitus, Experimental; Diabetic Retinopathy; DNA, Complementary; Female; Galactitol; Galactose; Galactosemias; Genotype; Humans; Lens, Crystalline; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Polymerase Chain Reaction	1995
Galactosemia produces ARI-preventable nodal changes similar to those of diabetic neuropathy. Diabetes research and clinical practice, 1994, Volume: 25, Issue:2 Topics: Aldehyde Reductase; Animals; Axons; Body Weight; Diabetic Neuropathies; Fructose; Galactitol; Galactose; Galactosemias; Inositol; Microscopy, Electron; Nerve Fibers, Myelinated; Nerve Regeneration; Neural Conduction; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sorbitol; Sural Nerve	1994
Galactose-induced retinal microangiopathy in rats. Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:2 Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Cataract; Diabetic Retinopathy; Disease Models, Animal; Erythrocytes; Galactitol; Galactose; Galactosemias; Imidazoles; Imidazolidines; Male; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; Sciatic Nerve	1995
Novel spirosuccinimide aldose reductase inhibitors derived from isoquinoline-1,3-diones: 2-[(4-bromo-2-fluorophenyl)methyl]-6- fluorospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and congeners. 1. Journal of medicinal chemistry, 1994, Jun-24, Volume: 37, Issue:13 Topics: Aldehyde Reductase; Animals; Blood Glucose; Cattle; Diabetes Mellitus, Experimental; Dogs; Drug Evaluation, Preclinical; Erythrocytes; Galactitol; Galactosemias; Glyceraldehyde; In Vitro Techniques; Isoquinolines; Lens, Crystalline; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spiro Compounds; Stereoisomerism	1994
Suppression of pentosidine formation in galactosemic rat lens by an inhibitor of aldose reductase. Diabetes, 1994, Volume: 43, Issue:4 Topics: Aldehyde Reductase; Animals; Arginine; Ascorbic Acid; Diet; Female; Galactitol; Galactose; Galactosemias; Glutathione; Imidazoles; Imidazolidines; Lens, Crystalline; Lysine; Maillard Reaction; Rats; Rats, Sprague-Dawley; Time Factors	1994
Effect of pregnancy on development of galactose-induced cataract in rat. Japanese journal of ophthalmology, 1993, Volume: 37, Issue:1 Topics: Animals; Cataract; Dietary Carbohydrates; Female; Galactitol; Galactose; Galactosemias; Incidence; Lens, Crystalline; Male; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley	1993
Long-term outcome in 134 patients with galactosaemia. European journal of pediatrics, 1993, Volume: 152, Issue:1 Topics: Adolescent; Adult; Cataract; Child; Child, Preschool; Female; Follow-Up Studies; Galactitol; Galactosemias; Galactosephosphates; Growth; Humans; Infant; Intelligence; Male; Microcephaly; Movement Disorders; Retrospective Studies; Speech Disorders; Uridine Diphosphate Galactose	1993
The effect of dietary fruits and vegetables on urinary galactitol excretion in galactose-1-phosphate uridyltransferase deficiency. Journal of inherited metabolic disease, 1993, Volume: 16, Issue:1 Topics: Adolescent; Adult; Diet; Erythrocytes; Female; Fruit; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; UTP-Hexose-1-Phosphate Uridylyltransferase; Vegetables	1993
Galactosemic neuropathy in transgenic mice for human aldose reductase. Diabetes, 1996, Volume: 45, Issue:1 Topics: Aldehyde Reductase; Animals; Base Sequence; DNA Primers; Female; Galactitol; Galactose; Galactosemias; Gene Expression Regulation, Enzymologic; Mice; Mice, Transgenic; Molecular Sequence Data; Neural Conduction; Peripheral Nervous System Diseases; Sciatic Nerve	1996
Glycolytic pathway, redox state of NAD(P)-couples and energy metabolism in lens in galactose-fed rats: effect of an aldose reductase inhibitor. Current eye research, 1997, Volume: 16, Issue:1 Topics: Aldehyde Reductase; Animals; Energy Metabolism; Enzyme Inhibitors; Galactitol; Galactose; Galactosemias; Gas Chromatography-Mass Spectrometry; Glycolysis; Inositol; Lens, Crystalline; Male; NADP; Naphthalenes; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley	1997
Topical aspirin provides protection against galactosemic cataract. Indian journal of ophthalmology, 1997, Volume: 45, Issue:4 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cataract; Diet; Galactitol; Galactosemias; Glutathione; Lens, Crystalline; Ophthalmic Solutions; Rats; Rats, Wistar	1997
Biochemical monitoring of treatment for galactosaemia: biological variability in metabolite concentrations. Journal of inherited metabolic disease, 1999, Volume: 22, Issue:2 Topics: Adolescent; Adult; Child; Child, Preschool; Galactitol; Galactosemias; Galactosephosphates; Humans; Infant; Infant, Newborn	1999
Homogeneous bioluminescence assay for galactosuria: interference and kinetic analysis. Analytical biochemistry, 1999, Jul-01, Volume: 271, Issue:2 Topics: Adenosine Triphosphate; False Positive Reactions; Galactitol; Galactokinase; Galactose; Galactosemias; Humans; Kinetics; Luciferases; Luminescent Measurements; Sensitivity and Specificity; Sugar Acids	1999
Cataract development in 12-month-old rats fed a 25% galactose diet and its relation to osmotic stress and oxidative damage. Ophthalmic research, 1999, Volume: 31, Issue:5 Topics: Animals; Body Water; Cataract; Cholesterol; Crystallins; Diet; Galactitol; Galactose; Galactosemias; Glutathione; Lens, Crystalline; Lipid Peroxides; Male; Osmotic Pressure; Oxidative Stress; Rats; Rats, Wistar; Vitamin E	1999
Subnormal retinal oxygenation response precedes diabetic-like retinopathy. Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:9 Topics: Animals; Blood Glucose; Carbon Dioxide; Diabetic Retinopathy; Fructose; Galactitol; Galactose; Galactosemias; Glucose; Inositol; Magnetic Resonance Imaging; Oxygen; Partial Pressure; Rats; Retina; Sorbitol	1999
Spontaneous pregnancy in a patient with classical galactosaemia. Journal of inherited metabolic disease, 1999, Volume: 22, Issue:6 Topics: Adult; Amniotic Fluid; Erythrocytes; Female; Galactitol; Galactosemias; Galactosephosphates; Heterozygote; Humans; Ovarian Diseases; Pregnancy; Pregnancy Complications; UTP-Hexose-1-Phosphate Uridylyltransferase	1999
Urine and plasma galactitol in patients with galactose-1-phosphate uridyltransferase deficiency galactosemia. Metabolism: clinical and experimental, 1999, Volume: 48, Issue:10 Topics: Adolescent; Age Factors; Amino Acid Substitution; Black People; Child; Child, Preschool; Codon, Terminator; Galactitol; Galactosemias; Genotype; Humans; Infant; Infant, Newborn; Point Mutation; Reference Values; Sequence Deletion; United States; UTP-Hexose-1-Phosphate Uridylyltransferase; White People	1999
Attenuation of sugar cataract by ethyl pyruvate. Molecular and cellular biochemistry, 1999, Volume: 200, Issue:1-2 Topics: Adenosine Triphosphate; Animals; Aqueous Humor; Cataract; Crystallins; Dietary Sucrose; Galactitol; Galactose; Galactosemias; Glycosylation; Male; Ophthalmic Solutions; Pyruvates; Rats; Rats, Sprague-Dawley	1999
Preventive effect of vitamin E-containing liposome instillation on cataract progression in 12-month-old rats fed a 25% galactose diet. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2000, Volume: 16, Issue:4 Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Body Water; Cataract; Cholesterol; Diet; Disease Progression; Drug Carriers; Galactitol; Galactose; Galactosemias; Glutathione; Lens, Crystalline; Lipid Peroxides; Liposomes; Male; Phosphatidylcholines; Rats; Rats, Wistar; Vitamin E	2000
Plasma galactose and galactitol concentration in patients with galactose-1-phosphate uridyltransferase deficiency galactosemia: determination by gas chromatography/mass spectrometry. Metabolism: clinical and experimental, 2000, Volume: 49, Issue:11 Topics: Adolescent; Adult; Child; Child, Preschool; Galactitol; Galactose; Galactosemias; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; UTP-Hexose-1-Phosphate Uridylyltransferase	2000
In vivo evidence of brain galactitol accumulation in an infant with galactosemia and encephalopathy. The Journal of pediatrics, 2001, Volume: 138, Issue:2 Topics: Brain; Brain Diseases, Metabolic, Inborn; Galactitol; Galactosemias; Humans; Infant, Newborn; Magnetic Resonance Spectroscopy; Male	2001
Identification of galactitol and galactonate in red blood cells by gas chromatography/mass spectrometry. Clinica chimica acta; international journal of clinical chemistry, 2002, Volume: 322, Issue:1-2 Topics: Erythrocytes; Galactitol; Galactosemias; Gas Chromatography-Mass Spectrometry; Humans; Sugar Acids	2002
Inhibition of polyol pathway activity in diabetic and galactosemic rats by the aldose reductase inhibitor CP-45,634. Advances in experimental medicine and biology, 1979, Volume: 119 Topics: Aldehyde Reductase; Animals; Blood Glucose; Cattle; Diabetes Mellitus, Experimental; Galactitol; Galactosemias; Lens, Crystalline; Male; Rats; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases; Sugar Alcohols	1979
CP-45,634: a novel aldose reductase inhibitor that inhibits polyol pathway activity in diabetic and galactosemic rats. Metabolism: clinical and experimental, 1979, Volume: 28, Issue:4 Suppl 1 Topics: Aldehyde Reductase; Animals; Benzopyrans; Cataract; Chromans; Diabetes Mellitus, Experimental; Galactitol; Galactose; Galactosemias; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Male; Polymers; Rats; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases	1979
Effect of gossypin, a flavonoid, on the formation of galactose-induced cataracts in rats. Experimental eye research, 1979, Volume: 29, Issue:3 Topics: Animals; Cataract; Female; Flavonoids; Galactitol; Galactosemias; Lens, Crystalline; Male; Rats	1979
Mannitol excretion in galactosemia patients. Clinica chimica acta; international journal of clinical chemistry, 1975, Oct-01, Volume: 64, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Glucose; Erythrocytes; Fructose; Galactitol; Galactose; Galactosemias; Humans; Mannitol	1975
Muscle and nerve dysfunction in rats with experimental galactosaemia. Experimental physiology, 1992, Volume: 77, Issue:1 Topics: Adenosine Triphosphatases; Aldehyde Reductase; Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Galactitol; Galactosemias; Male; Muscle Contraction; Muscles; Nervous System; Neural Conduction; Rats; Rats, Inbred Strains; Succinate Dehydrogenase	1992
Retinal polyol and myo-inositol in galactosemic dogs given an aldose-reductase inhibitor. Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:13 Topics: Aldehyde Reductase; Alloxan; Animals; Chromatography, Gas; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Erythrocytes; Galactitol; Galactosemias; Imidazoles; Imidazolidines; Inositol; Muscles; Retina	1991
Simultaneous determination of gluconolactone, galactonolactone and galactitol in urine by reversed-phase liquid chromatography: application to galactosemia. Journal of chromatography, 1991, Oct-04, Volume: 570, Issue:2 Topics: Chromatography, High Pressure Liquid; Female; Galactitol; Galactosemias; Gluconates; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lactones; Male; Spectrophotometry, Ultraviolet; Sugar Acids	1991
Urinary and serum galactitol in galactosemic patients. Acta paediatrica Japonica : Overseas edition, 1991, Volume: 33, Issue:1 Topics: Child; Child, Preschool; Galactitol; Galactose; Galactosemias; Humans; Infant; Male	1991
Metabolic studies of galactosemic cataract. Experimental eye research, 1990, Volume: 51, Issue:4 Topics: Animals; Cataract; Galactitol; Galactose; Galactosemias; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Phosphorus; Rats; Rats, Inbred Strains	1990
Effect of prolonged galactose consumption on galactose tolerance in young healthy humans. Annals of nutrition & metabolism, 1990, Volume: 34, Issue:1 Topics: Adult; Blood Glucose; Dietary Carbohydrates; Dose-Response Relationship, Drug; Female; Galactitol; Galactokinase; Galactose; Galactosemias; Glycosylation; Humans; Male; Sex Factors; Sugar Alcohols; Time Factors	1990
Lens hexitols and cataract formation during lactation in a woman heterozygote for galactosaemia. Journal of inherited metabolic disease, 1989, Volume: 12 Suppl 2 Topics: Adult; Cataract; Female; Galactitol; Galactokinase; Galactosemias; Genetic Carrier Screening; Humans; Inositol; Lactation; Lens, Crystalline; Male; Pregnancy; Pregnancy Complications; Reference Values; Sorbitol; Sugar Alcohols	1989
The prevention of biochemical changes in lens, retina, and nerve of galactosemic dogs by the aldose reductase inhibitor AL01576. Journal of ocular pharmacology, 1989,Fall, Volume: 5, Issue:3 Topics: Administration, Oral; Aldehyde Reductase; Analysis of Variance; Animals; Dogs; Fluorenes; Galactitol; Galactose; Galactosemias; Glutathione; Hydantoins; Inositol; Lens, Crystalline; Male; Retina; Sciatic Nerve; Sugar Alcohol Dehydrogenases	1989
Effect of 5% galactose diet on galactose and dulcitol in plasma and lens of male and female pigs. Annals of nutrition & metabolism, 1989, Volume: 33, Issue:6 Topics: Analysis of Variance; Animals; Dietary Carbohydrates; Female; Galactitol; Galactose; Galactosemias; Lens, Crystalline; Male; Sex Factors; Sugar Alcohols; Swine	1989
Effect of lactation in a mother with galactosemia. The Journal of pediatrics, 1989, Volume: 115, Issue:2 Topics: Adult; Female; Galactitol; Galactosemias; Galactosephosphates; Humans; Lactation; Milk, Human; Pregnancy; Puerperal Disorders	1989
Hyperglycemia and development of glomerular pathology: diabetes compared with galactosemia. Kidney international, 1989, Volume: 36, Issue:1 Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dogs; Galactitol; Galactosemias; Hyperglycemia; Kidney Glomerulus; Sorbitol	1989
Diabetic retinopathy: is it a consequence of hyperglycaemia? Diabetic medicine : a journal of the British Diabetic Association, 1985, Volume: 2, Issue:3 Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Dogs; Galactitol; Galactosemias; Hexoses; Hyperglycemia; Retina	1985
Glutathione depletion in the lens of galactosemic and diabetic rats. Experimental eye research, 1988, Volume: 46, Issue:4 Topics: Aldehyde Reductase; Aminoisobutyric Acids; Animals; Cell Membrane Permeability; Diabetes Mellitus, Experimental; Fluorenes; Galactitol; Galactosemias; Glutathione; Glutathione Reductase; Hydantoins; Lens, Crystalline; Male; NAD; NADP; Rats; Rats, Inbred Strains; Sorbitol	1988
Analysis of sorbitol, galactitol, and myo-inositol in lens and sciatic nerve by high-performance liquid chromatography. Analytical biochemistry, 1988, Aug-15, Volume: 173, Issue:1 Topics: Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Galactitol; Galactosemias; Inositol; Lens, Crystalline; Male; Rats; Rats, Inbred Strains; Sciatic Nerve; Sorbitol; Sugar Alcohols	1988
Dietary restriction of maternal lactose intake does not prevent accumulation of galactitol in the amniotic fluid of fetuses affected with galactosaemia. Prenatal diagnosis, 1988, Volume: 8, Issue:9 Topics: Adult; Amniotic Fluid; Female; Galactitol; Galactose; Galactosemias; Humans; Lactose; Pregnancy; Pregnancy Complications; Sugar Alcohols	1988
The development of electroretinogram abnormalities and the possible role of polyol pathway activity in diabetic hyperglycemia and galactosemia. Metabolism: clinical and experimental, 1988, Volume: 37, Issue:5 Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Electroretinography; Galactitol; Galactosemias; Hyperglycemia; Inositol; Insulin; Male; Oxazines; Pyrroles; Rats; Rats, Inbred Strains; Retina; Sorbitol; Sugar Alcohols	1988
[Influence of glucose on the conversion of galactose into galactitol in the young adult]. Annals of nutrition & metabolism, 1986, Volume: 30, Issue:3 Topics: Adult; Blood Glucose; Female; Galactitol; Galactose; Galactosemias; Glucose; Humans; Insulin; Male; Sugar Alcohols	1986
[Simple methods in the detection of galactose-1-phosphate and galactitol from samples on filter paper]. Kinderarztliche Praxis, 1987, Volume: 55, Issue:5 Topics: Galactitol; Galactosemias; Galactosephosphates; Hexosephosphates; Humans; Infant, Newborn; Mass Screening; Sugar Alcohols	1987
Galactose metabolism in male and female rats. II. Eye-ball differences. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1986, Volume: 56, Issue:3 Topics: Animals; Aqueous Humor; Cataract; Dietary Carbohydrates; Female; Galactitol; Galactose; Galactosemias; Glucose; Lactose; Lens, Crystalline; Male; Rats	1986
Galactose and galactitol in the urine of children with compound heterozygosity for Duarte variant and classical galactosemia (GtD/gt) after an oral galactose load. Clinical chemistry, 1985, Volume: 31, Issue:3 Topics: Aging; Child; Child, Preschool; Galactitol; Galactose; Galactosemias; Heterozygote; Humans; Infant; Sugar Alcohols	1985
Prevention of cataract development in severely galactosemic rats by the aldose reductase inhibitor, tolrestat. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 178, Issue:4 Topics: Animals; Cataract; Dose-Response Relationship, Drug; Galactitol; Galactose; Galactosemias; Humans; Lens, Crystalline; Male; Naphthalenes; Rats	1985
Galactitol accumulation and irreversible lens opacities in galactosemic rats. Investigative ophthalmology, 1973, Volume: 12, Issue:1 Topics: Animals; Cataract; Dietary Carbohydrates; Galactitol; Galactose; Galactosemias; Lens, Crystalline; Male; Rats; Remission, Spontaneous; Sugar Alcohols; Time Factors	1973
Urinary galactitol in galactosemic patients. Biochemical medicine, 1973, Volume: 7, Issue:2 Topics: Diet; Dietary Proteins; Erythrocytes; Galactitol; Galactose; Galactosemias; Humans; Phosphates; Sugar Alcohols; Time Factors	1973