galactitol has been researched along with Alloxan Diabetes in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (60.00) | 18.7374 |
| 1990's | 8 (32.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inatani, M; Matsumoto, T; Matsumura, T; Takamura, Y; Takihara, Y; Tomomatsu, T | 1 |
| Calcutt, NA; Cunha, JM; Gregory, JA; Jolivalt, CG; Mizisin, AP; Ramos, KM | 1 |
| Abraham, N; Bellini, F; Dvornik, D; Fung, S; Humber, L; Sestanj, K; Simard-Duquesne, N; Treasurywala, A | 1 |
| Low, PA; Schmelzer, JD; Tuck, RR | 1 |
| Callaert-Deveen, B; Dethy, JM; Janssens, M; Lenaers, A | 1 |
| Chung, SK; Chung, SS; Lee, AY | 1 |
| Hohman, TC; Malamas, MS; Millen, J | 1 |
| Epstein, M; Forster, HG; Hohman, TC; Takenaka, T; ter Wee, PM | 1 |
| Epstein, M; Forster, HG; Hohman, TC; ter Wee, PM | 1 |
| Banditelli, S; Boldrini, E; Cappiello, M; Cecconi, I; Dal Monte, M; Del Corso, A; Marini, I; Mura, U; Vilardo, PG | 1 |
| Aldinger, CE; MacDonald, DP; Peterson, MJ; Sarges, R | 2 |
| Hothersall, JS; McLean, P | 1 |
| Cameron, NE; Cotter, MA; Cox, D; Robertson, S | 1 |
| Engerman, RL; Kern, TS | 3 |
| Bauman, JG; Dietrich, A; Gorham, BJ; Harrison, MC; Jones, LR; Kelly, JM; Malamas, M; Millen, J; Sredy, J; Wrobel, J | 1 |
| Tomlinson, DR | 1 |
| Arimura, T; Ebata, K; Haneda, M; Kikkawa, R; Shigeta, Y; Umemura, K | 1 |
| Calcutt, NA; Tomlinson, DR; Willars, GB | 1 |
| Dickerson, JE; Garadi, R; Lou, MF; York, BM | 1 |
| Kanbara, M; Miwa, I; Okuda, J; Wakazono, H | 1 |
| Fujimori, S; Hirata, Y; Okada, K; Segawa, M | 1 |
| Earl, DC; Harrison, HE; Mirrlees, DJ; Stribling, D | 1 |
25 other study(ies) available for galactitol and Alloxan Diabetes
| Article | Year |
|---|---|
Aldose reductase inhibitor counteracts the enhanced expression of matrix metalloproteinase-10 and improves corneal wound healing in galactose-fed rats.
Topics: Administration, Oral; Administration, Topical; Aldehyde Reductase; Animals; Corneal Dystrophies, Hereditary; Diabetes Mellitus, Experimental; Diet; Enzyme Inhibitors; Epithelium, Corneal; Galactitol; Galactose; Gene Expression Regulation; Integrin alpha3; Male; Matrix Metalloproteinase 10; Rats; Rats, Sprague-Dawley; Signal Transduction; Wound Healing | 2013 |
Elevated lipid peroxidation and DNA oxidation in nerve from diabetic rats: effects of aldose reductase inhibition, insulin, and neurotrophic factors.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; DNA; Enzyme Inhibitors; Female; Galactitol; Galactose; Hydrazones; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Malondialdehyde; Nerve Growth Factors; Neurons; Nitroparaffins; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sulfones | 2008 |
N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Cattle; Diabetes Mellitus, Experimental; Galactitol; Isoquinolines; Lens, Crystalline; Naphthalenes; Rats; Sorbitol; Sugar Alcohol Dehydrogenases | 1984 |
Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy.
Topics: Animals; Blood Flow Velocity; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Galactitol; Galactose; Male; Neural Conduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Sciatic Nerve; Water-Electrolyte Balance | 1984 |
Determination of sorbitol and galactitol at the nanogram level in biological samples by high-performance liquid chromatography.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Erythrocytes; Fibroblasts; Galactitol; Humans; Lens, Crystalline; Microchemistry; Rats; Sciatic Nerve; Skin; Sorbitol; Sugar Alcohols | 1984 |
Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.
Topics: Aldehyde Reductase; Animals; Blotting, Southern; Cataract; Crosses, Genetic; Diabetes Mellitus, Experimental; Diabetic Retinopathy; DNA, Complementary; Female; Galactitol; Galactose; Galactosemias; Genotype; Humans; Lens, Crystalline; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Polymerase Chain Reaction | 1995 |
Novel spirosuccinimide aldose reductase inhibitors derived from isoquinoline-1,3-diones: 2-[(4-bromo-2-fluorophenyl)methyl]-6- fluorospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and congeners. 1.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Cattle; Diabetes Mellitus, Experimental; Dogs; Drug Evaluation, Preclinical; Erythrocytes; Galactitol; Galactosemias; Glyceraldehyde; In Vitro Techniques; Isoquinolines; Lens, Crystalline; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spiro Compounds; Stereoisomerism | 1994 |
Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat.
Topics: Animals; Arterioles; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diet; Disease Models, Animal; Galactitol; Galactose; Homeostasis; Hydronephrosis; Ibuprofen; In Vitro Techniques; Kidney; Male; Perfusion; Polymers; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1994 |
Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat is prevented by tolrestat.
Topics: Aldehyde Reductase; Angiotensin II; Animals; Arterioles; Blood Pressure; Cohort Studies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet; Disease Models, Animal; Enzyme Inhibitors; Galactitol; Galactose; Image Processing, Computer-Assisted; In Vitro Techniques; Kidney; Male; Muscle, Smooth, Vascular; Naphthalenes; Perfusion; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 1996 |
A new approach against sugar cataract through aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Enzyme Inhibitors; Galactitol; Galactose; Lens, Crystalline; Naphthalenes; Rats; Rats, Sprague-Dawley | 1999 |
Inhibition of polyol pathway activity in diabetic and galactosemic rats by the aldose reductase inhibitor CP-45,634.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Cattle; Diabetes Mellitus, Experimental; Galactitol; Galactosemias; Lens, Crystalline; Male; Rats; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases; Sugar Alcohols | 1979 |
CP-45,634: a novel aldose reductase inhibitor that inhibits polyol pathway activity in diabetic and galactosemic rats.
Topics: Aldehyde Reductase; Animals; Benzopyrans; Cataract; Chromans; Diabetes Mellitus, Experimental; Galactitol; Galactose; Galactosemias; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Male; Polymers; Rats; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases | 1979 |
Effect of experimental diabetes and insulin onphosphatidyl-inositol synthesis in rat sciatic nerve.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Galactitol; Galactose; Glucose; Inositol; Insulin; Male; Peripheral Nerves; Phosphatidylinositols; Rats; Sorbitol; Streptozocin | 1979 |
Muscle and nerve dysfunction in rats with experimental galactosaemia.
Topics: Adenosine Triphosphatases; Aldehyde Reductase; Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Galactitol; Galactosemias; Male; Muscle Contraction; Muscles; Nervous System; Neural Conduction; Rats; Rats, Inbred Strains; Succinate Dehydrogenase | 1992 |
Retinal polyol and myo-inositol in galactosemic dogs given an aldose-reductase inhibitor.
Topics: Aldehyde Reductase; Alloxan; Animals; Chromatography, Gas; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Erythrocytes; Galactitol; Galactosemias; Imidazoles; Imidazolidines; Inositol; Muscles; Retina | 1991 |
Syntheses of tolrestat analogues containing additional substituents in the ring and their evaluation as aldose reductase inhibitors. Identification of potent, orally active 2-fluoro derivatives.
Topics: Administration, Oral; Aldehyde Reductase; Animals; Cattle; Chemical Phenomena; Chemistry; Diabetes Mellitus, Experimental; Diaphragm; Galactitol; Galactose; Glycine; Lens, Crystalline; Male; Molecular Structure; Naphthalenes; Prodrugs; Rats; Rats, Inbred Strains; Sciatic Nerve | 1991 |
Polyols and myo-inositol in diabetic neuropathy--of mice and men.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Galactitol; Inositol; Mice; Peripheral Nerves; Rats; Sorbitol | 1989 |
Hyperglycemia and development of glomerular pathology: diabetes compared with galactosemia.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dogs; Galactitol; Galactosemias; Hyperglycemia; Kidney Glomerulus; Sorbitol | 1989 |
Diabetic retinopathy: is it a consequence of hyperglycaemia?
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Dogs; Galactitol; Galactosemias; Hexoses; Hyperglycemia; Retina | 1985 |
Evidence for existence of polyol pathway in cultured rat mesangial cells.
Topics: Aldehyde Reductase; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Galactitol; Glomerular Mesangium; L-Iditol 2-Dehydrogenase; Male; Rats; Rats, Inbred Strains; Sorbitol; Sugar Alcohols | 1987 |
Statil-sensitive polyol formation in nerve of galactose-fed mice.
Topics: Aldehyde Reductase; Animals; Carbohydrates; Diabetes Mellitus, Experimental; Galactitol; Galactose; Inositol; Mice; Mice, Inbred C57BL; Peripheral Nerves; Phthalazines; Pyridazines; Sorbitol; Sugar Alcohol Dehydrogenases; Sugar Alcohols | 1988 |
Glutathione depletion in the lens of galactosemic and diabetic rats.
Topics: Aldehyde Reductase; Aminoisobutyric Acids; Animals; Cell Membrane Permeability; Diabetes Mellitus, Experimental; Fluorenes; Galactitol; Galactosemias; Glutathione; Glutathione Reductase; Hydantoins; Lens, Crystalline; Male; NAD; NADP; Rats; Rats, Inbred Strains; Sorbitol | 1988 |
Analysis of sorbitol, galactitol, and myo-inositol in lens and sciatic nerve by high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Galactitol; Galactosemias; Inositol; Lens, Crystalline; Male; Rats; Rats, Inbred Strains; Sciatic Nerve; Sorbitol; Sugar Alcohols | 1988 |
The development of electroretinogram abnormalities and the possible role of polyol pathway activity in diabetic hyperglycemia and galactosemia.
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Electroretinography; Galactitol; Galactosemias; Hyperglycemia; Inositol; Insulin; Male; Oxazines; Pyrroles; Rats; Rats, Inbred Strains; Retina; Sorbitol; Sugar Alcohols | 1988 |
Properties of ICI 128,436, a novel aldose reductase inhibitor, and its effects on diabetic complications in the rat.
Topics: Aldehyde Reductase; Animals; Cataract; Cattle; Diabetes Mellitus, Experimental; Dogs; Erythrocytes; Fructose; Galactitol; Humans; In Vitro Techniques; Kidney Cortex; Lens, Crystalline; Male; Motor Neurons; Neural Conduction; Phthalazines; Pyridazines; Rats; Retina; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases | 1985 |