gadoxetic-acid-disodium has been researched along with Liver-Cirrhosis--Alcoholic* in 2 studies
2 other study(ies) available for gadoxetic-acid-disodium and Liver-Cirrhosis--Alcoholic
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Value of gadoxetic acid-enhanced MRI and diffusion-weighted imaging in the differentiation of hypervascular hyperplastic nodule from small (<3 cm) hypervascular hepatocellular carcinoma in patients with alcoholic liver cirrhosis: A retrospective case-cont
Hypervascular hyperplastic nodules (HHNs) occasionally develop in patients with alcoholic liver cirrhosis (ALC) and show arterial enhancement, thus mimicking hepatocellular carcinoma (HCC). Importantly, HHN as a benign lesion should be distinguished from HCC.. To evaluate the value of gadoxetic acid-enhanced MRI (Gd-EOB-MRI) and diffusion-weighted imaging (DWI) in distinguishing HHN from small (<3 cm) hypervascular HCC (hHCC) in patients with ALC.. Retrospective case-control study.. 3.0T/in- and out-of-phase, T. Among 560 patients with ALC who underwent Gd-EOB-MRI and DWI, 12 patients with 28 HHNs and 22 patients with 29 hHCCs smaller than 3 cm were included.. Univariate and multivariate analyses were performed to determine the significant MRI findings, and their diagnostic performance for the prediction of HHN was analyzed.. Lesion size of ≤16 mm (odds ratio [OR], 24.41; P = 0.007), low-to-iso SI on DWI (OR, 26.92; P = 0.007), and absence of washout on PVP and/or TP (OR, 31.84; P = 0.009) were significant independent factors for predicting HHN. When all three criteria were satisfied, the specificity was 100%. Compared with hHCCs, HHNs showed significantly smaller size (mean, 13.8 mm vs. 19.9 mm; P < 0.001) and higher mean SI value (994.0 vs. 669.5) and lesion-to-liver SI ratio (1.045 vs. 0.806) on HBP (P < 0.001, respectively).. Gd-EOB-MRI and DWI may be helpful in differentiating HHN from small hHCC in patients with ALC.. 3 Technical Efficacy Stage: 2 J. Magn. Reson. Imaging 2020;51:70-80. Topics: Adult; Aged; Carcinoma, Hepatocellular; Case-Control Studies; Contrast Media; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Gadolinium DTPA; Humans; Image Enhancement; Liver; Liver Cirrhosis, Alcoholic; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Retrospective Studies; Sensitivity and Specificity | 2020 |
[Q & A. Hepatic nodules complicated with alcoholic liver cirrhosis and presenting low signals in Gd-EOB-DTPA-contrasted MRI hepatocyte phase].
Topics: Aged; Focal Nodular Hyperplasia; Gadolinium DTPA; Humans; Liver Cirrhosis, Alcoholic; Magnetic Resonance Imaging; Male | 2011 |