gadoxetic-acid-disodium and Diabetes-Mellitus

gadoxetic-acid-disodium has been researched along with Diabetes-Mellitus* in 1 studies

Other Studies

1 other study(ies) available for gadoxetic-acid-disodium and Diabetes-Mellitus

Article	Year
Effect of nonenzymatic glycosylation on the magnetic resonance imaging (MRI) contrast agent binding to human serum albumin. Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8 Enhanced nonenzymatic glycosylation (NEG) of human serum albumin (HSA) is observed in diabetic patients. This modifies some of the physiological functions of HSA, as the binding of ligands. Some gadolinium complexes, commonly used as MRI contrast agents, have a high affinity for HSA, which enhances their efficacy. The aim of this study is to evaluate the possible influence of the NEG of HSA on its affinity for some gadolinium chelates. Topics: Chelating Agents; Contrast Media; Diabetes Mellitus; Gadolinium; Gadolinium DTPA; Glycosylation; Humans; Nuclear Magnetic Resonance, Biomolecular; Organometallic Compounds; Serum Albumin	2012

Article

Year

Effect of nonenzymatic glycosylation on the magnetic resonance imaging (MRI) contrast agent binding to human serum albumin.

Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8

Enhanced nonenzymatic glycosylation (NEG) of human serum albumin (HSA) is observed in diabetic patients. This modifies some of the physiological functions of HSA, as the binding of ligands. Some gadolinium complexes, commonly used as MRI contrast agents, have a high affinity for HSA, which enhances their efficacy. The aim of this study is to evaluate the possible influence of the NEG of HSA on its affinity for some gadolinium chelates.

Topics: Chelating Agents; Contrast Media; Diabetes Mellitus; Gadolinium; Gadolinium DTPA; Glycosylation; Humans; Nuclear Magnetic Resonance, Biomolecular; Organometallic Compounds; Serum Albumin

2012