gaboxadol has been researched along with Schizophrenia in 3 studies
gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The psychotomimetic NMDA receptor antagonist phencyclidine (PCP) is frequently employed to model schizophrenia in animal disease models." | 3.77 | Extrasynaptic GABAA receptor activation reverses recognition memory deficits in an animal model of schizophrenia. ( Damgaard, T; Hansen, SL; Neill, JC; Plath, N, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Damgaard, T | 1 |
| Plath, N | 1 |
| Neill, JC | 1 |
| Hansen, SL | 1 |
| Emrich, HM | 1 |
| Altmann, H | 1 |
| Dose, M | 1 |
| von Zerssen, D | 1 |
| Thaker, GK | 1 |
| Tamminga, CA | 1 |
| Alphs, LD | 1 |
| Lafferman, J | 1 |
| Ferraro, TN | 1 |
| Hare, TA | 1 |
2 trials available for gaboxadol and Schizophrenia
| Article | Year |
|---|---|
Therapeutic effects of GABA-ergic drugs in affective disorders. A preliminary report.
Topics: Adolescent; Adult; Analgesics; Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as | 1983 |
Brain gamma-aminobutyric acid abnormality in tardive dyskinesia. Reduction in cerebrospinal fluid GABA levels and therapeutic response to GABA agonist treatment.
Topics: Adult; Aminocaproates; Brain; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induce | 1987 |
1 other study available for gaboxadol and Schizophrenia
| Article | Year |
|---|---|
Extrasynaptic GABAA receptor activation reverses recognition memory deficits in an animal model of schizophrenia.
Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, | 2011 |