gaboxadol has been researched along with Rett Syndrome in 2 studies
gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure
Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhong, W | 2 |
| Cui, N | 2 |
| Jin, X | 1 |
| Oginsky, MF | 1 |
| Wu, Y | 2 |
| Zhang, S | 1 |
| Bondy, B | 1 |
| Johnson, CM | 2 |
| Jiang, C | 2 |
| Xing, H | 1 |
2 other studies available for gaboxadol and Rett Syndrome
| Article | Year |
|---|---|
Methyl CpG Binding Protein 2 Gene Disruption Augments Tonic Currents of γ-Aminobutyric Acid Receptors in Locus Coeruleus Neurons: IMPACT ON NEURONAL EXCITABILITY AND BREATHING.
Topics: Animals; Bicuculline; GABA Agonists; GABAergic Neurons; Humans; Isoxazoles; Locus Coeruleus; Methyl- | 2015 |
Effects of chronic exposure to low dose THIP on brainstem neuronal excitability in mouse models of Rett syndrome: Evidence from symptomatic females.
Topics: Animals; Brain Stem; Disease Models, Animal; Dose-Response Relationship, Drug; Double-Blind Method; | 2017 |