gaboxadol has been researched along with Pain in 9 studies
gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "D-Baclofen is an antagonist at spinal baclofen receptors." | 1.27 | GABAergic mechanisms in antinociception. ( Sawynok, J, 1984) |
| " The maximum serum concentration was reached within 1 h after dosing in 87% of all administrations." | 1.27 | The analgesic effect of the GABA-agonist THIP in patients with chronic pain of malignant origin. A phase-1-2 study. ( Kjaer, M; Nielsen, H, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, JP | 1 |
| He, YT | 1 |
| Duan, XL | 1 |
| Suo, ZW | 1 |
| Yang, X | 1 |
| Hu, XD | 1 |
| Sawynok, J | 1 |
| Kjaer, M | 1 |
| Nielsen, H | 1 |
| Lindeburg, T | 1 |
| Følsgård, S | 1 |
| Sillesen, H | 1 |
| Jacobsen, E | 1 |
| Kehlet, H | 1 |
| Menon, MK | 1 |
| Clark, WG | 1 |
| Vivonia, C | 1 |
| Reyes-Vazquez, C | 1 |
| Enna, SJ | 2 |
| Dafny, N | 1 |
| Zorn, SH | 1 |
| Drower, EJ | 1 |
| Hammond, DL | 1 |
| Pelley, KA | 1 |
| Vaught, JL | 1 |
9 other studies available for gaboxadol and Pain
| Article | Year |
|---|---|
Enhanced Activities of δ Subunit-containing GABA
Topics: Animals; Dose-Response Relationship, Drug; Formaldehyde; GABA-A Receptor Agonists; Isoxazoles; Long- | 2018 |
GABAergic mechanisms in antinociception.
Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Analgesics; Animals; Baclofen; Bicuculline; Central Ne | 1984 |
The analgesic effect of the GABA-agonist THIP in patients with chronic pain of malignant origin. A phase-1-2 study.
Topics: Adult; Aged; Analgesics; Analysis of Variance; Chronic Disease; Drug Evaluation; Female; Humans; Iso | 1983 |
Analgesic, respiratory and endocrine responses in normal man to THIP, a GABA-agonist.
Topics: Adult; Analgesics; Dental Pulp Test; Double-Blind Method; Hormones; Humans; Hydrocortisone; Isoxazol | 1983 |
Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications.
Topics: Aminooxyacetic Acid; Anesthesia; Animals; Baclofen; Dextroamphetamine; Diazepam; Drug Interactions; | 1980 |
The parafasciculus thalami as a site for mediating the antinociceptive response to GABAergic drugs.
Topics: Animals; gamma-Aminobutyric Acid; Isoxazoles; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Rece | 1986 |
The GABA agonist THIP, attenuates antinociception in the mouse by modifying central cholinergic transmission.
Topics: Afferent Pathways; Analgesics; Animals; Central Nervous System; Cholinergic Fibers; GABA Antagonists | 1987 |
GABAergic modulation of nociceptive threshold: effects of THIP and bicuculline microinjected in the ventral medulla of the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Isoxazoles; Male; Medulla Oblongata; Microinjections; | 1988 |
An antinociceptive profile of kojic amine: an analogue of gamma-aminobutyric acid (GABA).
Topics: Animals; Atropine; Atropine Derivatives; Baclofen; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; | 1987 |