gaboxadol has been researched along with Fragile X Syndrome in 3 studies
gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martin, BS | 2 |
| Corbin, JG | 3 |
| Huntsman, MM | 2 |
| Olmos-Serrano, JL | 2 |
| Paluszkiewicz, SM | 1 |
| Kaufmann, WE | 1 |
| Burns, MP | 1 |
3 other studies available for gaboxadol and Fragile X Syndrome
| Article | Year |
|---|---|
Deficient tonic GABAergic conductance and synaptic balance in the fragile X syndrome amygdala.
Topics: Amygdala; Animals; Excitatory Postsynaptic Potentials; Feedback, Physiological; Fragile X Mental Ret | 2014 |
Defective GABAergic neurotransmission and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of fragile X syndrome.
Topics: Amygdala; Animals; Disease Models, Animal; Evoked Potentials; Fragile X Mental Retardation Protein; | 2010 |
The GABA(A) receptor agonist THIP ameliorates specific behavioral deficits in the mouse model of fragile X syndrome.
Topics: Animals; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Fear; Fragile X Ment | 2011 |