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gaboxadol and Dyskinesia, Drug-Induced

gaboxadol has been researched along with Dyskinesia, Drug-Induced in 7 studies

gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure

Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)

Research Excerpts

ExcerptRelevanceReference
"Side effects included sedation, confusion, dizziness, vomiting, and myoclonic jerks."2.65The effect of tetrahydroisoxazolopyridinol (THIP) in tardive dyskinesia: a new gamma-aminobutyric acid agonist. ( Casey, DE; Gerlach, J; Hetmar, O; Kaldan, B; Korsgaard, S; Mikkelsen, LB, 1982)
"Tetrahydroisoxazolopyridinol (THIP), a GABA receptor agonist, gamma-acetylenic-GABA(GAG) and gamma-vinyl-GABA(GVG), two GABA transaminase inhibitors were given in single parenteral doses to three Cebus apella monkeys with persistent dyskinetic movements induced by earlier long-term administration of haloperidol."1.27GABA agonists in cebus monkeys with neuroleptic-induced persistent dyskinesias. ( Andersson, U; Häggström, JE, 1988)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alabed, S1
Latifeh, Y1
Mohammad, HA1
Bergman, H1
Peixoto, MF1
Araujo, NP1
Silva, RH1
Castro, JP1
Fukushiro, DF1
Faria, RR1
Zanier-Gomes, PH1
Medrano, WA1
Frussa-Filho, R1
Abílio, VC1
Korsgaard, S1
Casey, DE1
Gerlach, J2
Hetmar, O1
Kaldan, B1
Mikkelsen, LB1
Thaker, GK2
Hare, TA2
Tamminga, CA2
Bjørndal, N1
Christensson, E1
Andersson, U1
Häggström, JE1
Alphs, LD1
Lafferman, J1
Ferraro, TN1

Reviews

2 reviews available for gaboxadol and Dyskinesia, Drug-Induced

ArticleYear
Gamma-aminobutyric acid agonists for antipsychotic-induced tardive dyskinesia.
    The Cochrane database of systematic reviews, 2018, 04-17, Volume: 4

    Topics: Antipsychotic Agents; Baclofen; Dyskinesia, Drug-Induced; GABA Agonists; gamma-Aminobutyric Acid; Hu

2018
GABA system: clinical research and treatment of tardive dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyski

1983

Trials

3 trials available for gaboxadol and Dyskinesia, Drug-Induced

ArticleYear
The effect of tetrahydroisoxazolopyridinol (THIP) in tardive dyskinesia: a new gamma-aminobutyric acid agonist.
    Archives of general psychiatry, 1982, Volume: 39, Issue:9

    Topics: Adult; Aged; Analgesics; Antipsychotic Agents; Blinking; Clinical Trials as Topic; Confusion; Dizzin

1982
GABA system: clinical research and treatment of tardive dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyski

1983
Brain gamma-aminobutyric acid abnormality in tardive dyskinesia. Reduction in cerebrospinal fluid GABA levels and therapeutic response to GABA agonist treatment.
    Archives of general psychiatry, 1987, Volume: 44, Issue:6

    Topics: Adult; Aminocaproates; Brain; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induce

1987

Other Studies

3 other studies available for gaboxadol and Dyskinesia, Drug-Induced

ArticleYear
Effects of gabaergic drugs on reserpine-induced oral dyskinesia.
    Behavioural brain research, 2005, May-07, Volume: 160, Issue:1

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Baclofen; Behavior, Animal; Diazepam; Dose-Resp

2005
Methylphenidate, apomorphine, THIP, and diazepam in monkeys: dopamine-GABA behavior related to psychoses and tardive dyskinesia.
    Psychopharmacology, 1984, Volume: 82, Issue:1-2

    Topics: Animals; Apomorphine; Chlorocebus aethiops; Diazepam; Dopamine; Drug Interactions; Dyskinesia, Drug-

1984
GABA agonists in cebus monkeys with neuroleptic-induced persistent dyskinesias.
    Psychopharmacology, 1988, Volume: 94, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Antipsychotic Agents; Cebus; Dyskine

1988