gaboxadol has been researched along with Drug Withdrawal Symptoms in 5 studies
gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intraperitoneal injection of ethanol (1-2 g/kg) and chlordiazepoxide (2-16 mg/kg) suppressed susceptibility to audiogenically induced, clonic-tonic seizures and antagonized forelimb tremor in rats undergoing ethanol withdrawal, 30 min after treatment." | 7.66 | Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. ( Breese, GR; Frye, GD; McCown, TJ, 1983) |
| "Intraperitoneal injection of ethanol (1-2 g/kg) and chlordiazepoxide (2-16 mg/kg) suppressed susceptibility to audiogenically induced, clonic-tonic seizures and antagonized forelimb tremor in rats undergoing ethanol withdrawal, 30 min after treatment." | 3.66 | Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. ( Breese, GR; Frye, GD; McCown, TJ, 1983) |
| "Gaboxadol 15mg treatment for 2 weeks significantly improved sleep onset and maintenance variables as well as sleep quality and daytime function, as did zolpidem." | 2.74 | A 2-week efficacy and safety study of gaboxadol and zolpidem using electronic diaries in primary insomnia outpatients. ( Eglin, M; Hajak, G; Hedner, J; Loft, H; Lundahl, J; Lütolf, S; Stórustovu, SI, 2009) |
| "Gaboxadol (1." | 1.32 | Progesterone withdrawal increases the anxiolytic actions of gaboxadol: role of alpha4betadelta GABA(A) receptors. ( Gong, QH; Gulinello, M; Smith, SS, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hajak, G | 1 |
| Hedner, J | 1 |
| Eglin, M | 1 |
| Loft, H | 1 |
| Stórustovu, SI | 1 |
| Lütolf, S | 1 |
| Lundahl, J | 1 |
| Gulinello, M | 1 |
| Gong, QH | 1 |
| Smith, SS | 1 |
| Liang, J | 1 |
| Cagetti, E | 1 |
| Olsen, RW | 1 |
| Spigelman, I | 1 |
| Frye, GD | 1 |
| McCown, TJ | 1 |
| Breese, GR | 1 |
| Zharkovskiĭ, AM | 1 |
| Zharkovskaia, TA | 1 |
1 trial available for gaboxadol and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
A 2-week efficacy and safety study of gaboxadol and zolpidem using electronic diaries in primary insomnia outpatients.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Diagnostic and Statistical Manual of Mental Disorders; Dou | 2009 |
4 other studies available for gaboxadol and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Progesterone withdrawal increases the anxiolytic actions of gaboxadol: role of alpha4betadelta GABA(A) receptors.
Topics: Animals; Anti-Anxiety Agents; Drug Implants; Female; GABA Agonists; Hippocampus; Ion Channels; Isoxa | 2003 |
Altered pharmacology of synaptic and extrasynaptic GABAA receptors on CA1 hippocampal neurons is consistent with subunit changes in a model of alcohol withdrawal and dependence.
Topics: Alcoholism; Animals; Azides; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; GABA Agonists; H | 2004 |
Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors.
Topics: 4-Aminobutyrate Transaminase; Acoustic Stimulation; Aminobutyrates; Animals; Chlordiazepoxide; Disea | 1983 |
[Antiabstinent action of fenibut and baclofen on a model of abstinence induced by the benzodiazepine receptor antagonist CGS 8216 in rats receiving diazepam].
Topics: Animals; Baclofen; Behavior, Animal; Diazepam; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid | 1987 |