gaboxadol has been researched along with Disorders of Excessive Somnolence in 2 studies
gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure
Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gaboxadol was generally well-tolerated; there were no serious adverse experiences and no subjects discontinued due to an adverse experience." | 2.74 | Next-day residual effects of gaboxadol and flurazepam administered at bedtime: a randomized double-blind study in healthy elderly subjects. ( Boyle, J; Cerchio, K; Cummings, C; Gargano, C; Lines, C; McCrea, J; Wolford, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walsh, JK | 1 |
| Snyder, E | 1 |
| Hall, J | 1 |
| Randazzo, AC | 1 |
| Griffin, K | 1 |
| Groeger, J | 1 |
| Eisenstein, R | 1 |
| Feren, SD | 1 |
| Dickey, P | 1 |
| Schweitzer, PK | 1 |
| Boyle, J | 1 |
| Wolford, D | 1 |
| Gargano, C | 1 |
| McCrea, J | 1 |
| Cummings, C | 1 |
| Cerchio, K | 1 |
| Lines, C | 1 |
2 trials available for gaboxadol and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Slow wave sleep enhancement with gaboxadol reduces daytime sleepiness during sleep restriction.
Topics: Adult; Affect; Arousal; Attention; Circadian Rhythm; Disorders of Excessive Somnolence; Double-Blind | 2008 |
Next-day residual effects of gaboxadol and flurazepam administered at bedtime: a randomized double-blind study in healthy elderly subjects.
Topics: Administration, Oral; Aged; Cross-Over Studies; Disorders of Excessive Somnolence; Double-Blind Meth | 2009 |