gaboxadol and Ataxia
gaboxadol has been researched along with Ataxia in 3 studies
gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Muscimol was a more potent stimulator of 36Cl- flux in the DS compared to the DR mice, although no difference between the lines was found in muscimol-stimulation of [3H]flunitrazepam binding." | 1.27 | Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex. ( Allan, AM; Gallaher, EJ; Gionet, SE; Harris, RA, 1988) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Madsen, KK | 1 |
| Ebert, B | 1 |
| Clausen, RP | 1 |
| Krogsgaard-Larsen, P | 1 |
| Schousboe, A | 1 |
| White, HS | 1 |
| Maas, JW | 1 |
| Vogt, SK | 1 |
| Chan, GC | 1 |
| Pineda, VV | 1 |
| Storm, DR | 1 |
| Muglia, LJ | 1 |
| Allan, AM | 1 |
| Gallaher, EJ | 1 |
| Gionet, SE | 1 |
| Harris, RA | 1 |
Other Studies
3 other studies available for gaboxadol and Ataxia
| Article | Year |
|---|---|
Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol.
Topics: Animals; Anticonvulsants; Ataxia; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Plas | 2011 |
Calcium-stimulated adenylyl cyclases are critical modulators of neuronal ethanol sensitivity.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Ataxia; Behavior, Animal; Blotting, Western; Calci | 2005 |
Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex.
Topics: Animals; Ataxia; Chlorides; Diazepam; Ethanol; Flunitrazepam; Ion Channels; Isoxazoles; Mice; Muscim | 1988 |