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gaboxadol and Ataxia

gaboxadol has been researched along with Ataxia in 3 studies

gaboxadol: GABA agonist; inhibitor of GABA uptake systems; structure

Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"Muscimol was a more potent stimulator of 36Cl- flux in the DS compared to the DR mice, although no difference between the lines was found in muscimol-stimulation of [3H]flunitrazepam binding."1.27Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex. ( Allan, AM; Gallaher, EJ; Gionet, SE; Harris, RA, 1988)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Madsen, KK1
Ebert, B1
Clausen, RP1
Krogsgaard-Larsen, P1
Schousboe, A1
White, HS1
Maas, JW1
Vogt, SK1
Chan, GC1
Pineda, VV1
Storm, DR1
Muglia, LJ1
Allan, AM1
Gallaher, EJ1
Gionet, SE1
Harris, RA1

Other Studies

3 other studies available for gaboxadol and Ataxia

ArticleYear
Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 338, Issue:1

    Topics: Animals; Anticonvulsants; Ataxia; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Plas

2011
Calcium-stimulated adenylyl cyclases are critical modulators of neuronal ethanol sensitivity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Apr-20, Volume: 25, Issue:16

    Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Ataxia; Behavior, Animal; Blotting, Western; Calci

2005
Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex.
    Brain research, 1988, Jun-14, Volume: 452, Issue:1-2

    Topics: Animals; Ataxia; Chlorides; Diazepam; Ethanol; Flunitrazepam; Ion Channels; Isoxazoles; Mice; Muscim

1988