gabexate has been researched along with Skin Neoplasms in 6 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Skin Neoplasms: Tumors or cancer of the SKIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 64-year-old man was diagnosed with acute myeloid leukemia (AML) complicated by disseminated intravascular coagulation." | 1.35 | Leukemia cutis originating in the extravasation site of i.v. gabexate mesilate infusion. ( Aota, Y; Iguchi, T; Kurashige, Y; Miyakura, T; Nagai, A; Tsuboi, R; Yamamoto, T, 2008) |
| " This drug at a dosage of 10 mg/kg or 20 mg/kg was administered by ip injection to 20 mice each harboring a solitary tumor twice daily for 10 weeks." | 1.26 | Inhibition of growth of 3-methylcholanthrene-induced mouse skin tumor by protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate. ( Ohkoshi, M, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miyakura, T | 1 |
| Yamamoto, T | 1 |
| Kurashige, Y | 1 |
| Nagai, A | 1 |
| Iguchi, T | 1 |
| Aota, Y | 1 |
| Tsuboi, R | 1 |
| Ohkoshi, M | 5 |
| Fujii, S | 3 |
1 review available for gabexate and Skin Neoplasms
| Article | Year |
|---|---|
[Protease inhibitors as anticancer chemotherapy--experimental and clinical studies].
Topics: Adenocarcinoma; Animals; Carcinoma, Lewis Lung; Carcinoma, Squamous Cell; Cell Division; Colonic Neo | 1995 |
5 other studies available for gabexate and Skin Neoplasms