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gabexate and Shock

gabexate has been researched along with Shock in 8 studies

Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of gabexate-mesilate (FOY) in circulatory shock in man."9.07[Gabexate mesilate (FOY), a new synthetic protease inhibitor, in the treatment of shock. An Italian multicenter study]. ( Innocenti, P; Livi, P; Novelli, GP, 1993)
"To evaluate the efficacy of gabexate-mesilate (FOY) in circulatory shock in man."5.07[Gabexate mesilate (FOY), a new synthetic protease inhibitor, in the treatment of shock. An Italian multicenter study]. ( Innocenti, P; Livi, P; Novelli, GP, 1993)
"Protease inhibitors, such as ulinastatin and gabexate mesilate, are widely used for the patients in shock state."3.67[The effect of protease inhibitors in shock]. ( Endo, Y; Inoue, H; Miura, J; Motoki, R; Terashima, S; Usuba, A; Watanabe, M, 1989)
"The effect of the epsilon-guanidino acid derivate camostate (FOY 305) on lipolysis of isolated adipocytes was evaluated to test its supposed influence on the reactions of lipid metabolism in experimental shock."3.67Influence of a low molecular weight serine proteinase inhibitor (camostate) on lipolysis of isolated adipocytes. ( Göke, B; Göke, R; Lankisch, PG, 1985)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyazaki, M1
Yoda, K1
Ogli, K1
Yokono, S1
Novelli, GP1
Innocenti, P1
Livi, P1
Mitsuoka, H1
Kistler, EB1
Schmid-Schönbein, GW1
Kashima, K1
Kataoka, K1
Umehara, K1
Motoki, R2
Inoue, H2
Usuba, A1
Endo, Y1
Terashima, S1
Watanabe, M1
Miura, J1
Schlag, G1
Redl, H1
Göke, B1
Göke, R1
Lankisch, PG1

Trials

1 trial available for gabexate and Shock

ArticleYear
[Gabexate mesilate (FOY), a new synthetic protease inhibitor, in the treatment of shock. An Italian multicenter study].
    Minerva anestesiologica, 1993, Volume: 59, Issue:5

    Topics: Adolescent; Adult; Aged; Female; Follow-Up Studies; Gabexate; Humans; Italy; Male; Middle Aged; Shoc

1993

Other Studies

7 other studies available for gabexate and Shock

ArticleYear
[Problems in the use of newly introduced anti-shock agents].
    Masui. The Japanese journal of anesthesiology, 1983, Volume: 32, Issue:10

    Topics: Adrenal Cortex Hormones; Animals; Benzamidines; Complement Inactivator Proteins; Gabexate; Guanidine

1983
Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock.
    Shock (Augusta, Ga.), 2002, Volume: 17, Issue:3

    Topics: Animals; Blood Pressure; Endopeptidases; Esters; Gabexate; Guanidines; Humans; In Vitro Techniques;

2002
[Treatment of acute pancreatitis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Dec-10, Volume: 81, Issue:12

    Topics: Acute Disease; Benzamidines; Disseminated Intravascular Coagulation; Drainage; Gabexate; Glycoprotei

1992
[Protease inhibitors in shock].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Aprotinin; Disseminated Intravascular Coagulation; Gabexate; Glycoproteins; Humans; Infant, Newborn;

1991
[The effect of protease inhibitors in shock].
    Nihon Geka Gakkai zasshi, 1989, Volume: 90, Issue:9

    Topics: Animals; Blood Coagulation Disorders; Dogs; Gabexate; Glycoproteins; Guanidines; Humans; Kidney; Ser

1989
The proteinases in shock.
    Resuscitation, 1986, Volume: 14, Issue:1-2

    Topics: Blood Coagulation; Endopeptidases; Fibrinolysis; Gabexate; Granulocytes; Guanidines; Humans; Kallikr

1986
Influence of a low molecular weight serine proteinase inhibitor (camostate) on lipolysis of isolated adipocytes.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1985, Volume: 185, Issue:6

    Topics: Adipose Tissue; Animals; Esters; Gabexate; Guanidines; Lipolysis; Male; Rats; Rats, Inbred Strains;

1985