Page last updated: 2024-10-27

gabexate and Proteinuria

gabexate has been researched along with Proteinuria in 9 studies

Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"The effects of camostat mesilate (CM), a derivative of gabexate mesilate developed for oral use, on primary glomerulonephritis (GN) and chance hematuria and/or proteinuria were evaluated."9.11Effect of oral camostat mesilate on hematuria and/or proteinuria in children. ( Asami, T; Tomisawa, S; Uchiyama, M, 2004)
"Camostat mesilate, a developed derivative of gabexate mesilate for oral use, was administered in a daily dose of 600 mg for 4 weeks to 17 patients with heavy proteinuria due to various nephropathies."7.67Effect of camostat mesilate on heavy proteinuria in various nephropathies. ( Futaki, G; Hotta, O; Kurosawa, K; Matsubara, M; Suzuki, K; Taguma, Y, 1989)
"The effects of camostat mesilate (CM), a derivative of gabexate mesilate developed for oral use, on primary glomerulonephritis (GN) and chance hematuria and/or proteinuria were evaluated."5.11Effect of oral camostat mesilate on hematuria and/or proteinuria in children. ( Asami, T; Tomisawa, S; Uchiyama, M, 2004)
"Effect of serine protease inhibitor Camostat Mesilate (Foipan) on primary glomerulonephritis and it's mechanism were evaluated."3.68[Effect of protease inhibitor on primary glomerulonephritis and the mechanism of the effect]. ( Fukushima, M; Haramoto, T; Kumagai, I; Makino, H; Murakami, K; Ogura, T; Onbe, T; Ota, Z; Wada, J, 1991)
"Camostat mesilate, a developed derivative of gabexate mesilate for oral use, was administered in a daily dose of 600 mg for 4 weeks to 17 patients with heavy proteinuria due to various nephropathies."3.67Effect of camostat mesilate on heavy proteinuria in various nephropathies. ( Futaki, G; Hotta, O; Kurosawa, K; Matsubara, M; Suzuki, K; Taguma, Y, 1989)
"The number of the chronic renal failure (CRF) patients is increasing explosively."1.38Effect of a serine protease inhibitor on the progression of chronic renal failure. ( Adachi, M; Hayata, M; Kakizoe, Y; Kitamura, K; Miyoshi, T; Mizumoto, T; Morinaga, J; Onoue, T; Sakai, Y; Shiraishi, N; Tomita, K; Uchimura, K; Ueda, M; Yamazoe, R, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's6 (66.67)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayata, M1
Kakizoe, Y1
Uchimura, K1
Morinaga, J1
Yamazoe, R1
Mizumoto, T1
Onoue, T1
Ueda, M1
Shiraishi, N1
Adachi, M1
Miyoshi, T1
Sakai, Y1
Tomita, K1
Kitamura, K1
Asami, T1
Tomisawa, S1
Uchiyama, M1
Ueda, Y1
Nagasawa, K1
Tsukamoto, H1
Horiuchi, T1
Yoshizawa, S1
Tsuru, T1
Furugo, I1
Niho, Y1
Matsubara, M3
Taguma, Y3
Saito, T2
Yoshinaga, K2
Onbe, T2
Makino, H2
Haramoto, T1
Wada, J1
Ogura, T1
Kumagai, I2
Murakami, K2
Fukushima, M1
Ota, Z2
Nakayama, S1
Koide, H1
Kurosawa, K1
Hotta, O1
Suzuki, K1
Futaki, G1

Trials

3 trials available for gabexate and Proteinuria

ArticleYear
Effect of oral camostat mesilate on hematuria and/or proteinuria in children.
    Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:3

    Topics: Administration, Oral; Adolescent; Biopsy; Child; Child, Preschool; Esters; Female; Follow-Up Studies

2004
Urinary C4 excretion in systemic lupus erythematosus.
    Clinica chimica acta; international journal of clinical chemistry, 1995, Dec-15, Volume: 243, Issue:1

    Topics: Adolescent; Adult; Blotting, Western; Complement Activation; Complement C4; DNA; Esters; Female; Gab

1995
Anti-proteinuric and anti-coagulatory effects of camostat mesilate in azotemic diabetics.
    Nihon Jinzo Gakkai shi, 1992, Volume: 34, Issue:4

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Blood Coagulation; Captopril;

1992

Other Studies

6 other studies available for gabexate and Proteinuria

ArticleYear
Effect of a serine protease inhibitor on the progression of chronic renal failure.
    American journal of physiology. Renal physiology, 2012, Oct-15, Volume: 303, Issue:8

    Topics: Animals; Creatinine; Disease Progression; Esters; Gabexate; Guanidines; Kidney; Kidney Failure, Chro

2012
Effect of camostat mesilate on persistent proteinuria of IgA nephropathy.
    Nephron, 1992, Volume: 60, Issue:2

    Topics: Administration, Oral; Adult; Esters; Female; Gabexate; Glomerulonephritis, IGA; Guanidines; Humans;

1992
[Effect of protease inhibitor on primary glomerulonephritis and the mechanism of the effect].
    Nihon Jinzo Gakkai shi, 1991, Volume: 33, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Urea Nitrogen; Complement System Proteins; Creatin

1991
A proteinase inhibitor reduces proteinuria in nephrotic syndrome.
    American journal of nephrology, 1991, Volume: 11, Issue:2

    Topics: Esters; Gabexate; Guanidines; Humans; Nephrotic Syndrome; Protease Inhibitors; Proteinuria

1991
[Clinical application of proteinase inhibitors to renal diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Antithrombins; Esters; Free Radical Scavengers; Gabexate; Guanidines; Humans; Kidney Diseases; Prote

1991
Effect of camostat mesilate on heavy proteinuria in various nephropathies.
    Clinical nephrology, 1989, Volume: 32, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Esters; Female; Gabexate; Glomerulonephritis; Glycosu

1989