gabexate has been researched along with Pregnancy in 10 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of acute pancreatitis, which occurred after delivery in a woman who had an uneventful course of pregnancy and parturition." | 1.32 | Acute pancreatitis occurring in the early postpartum period: a case report. ( Chaen, H; Eguchi, F; Fukami, T; Imura, H; Sudou, K, 2003) |
| "These changes included acute disseminated intravascular coagulation, severe elevations of liver enzymes, severe renal dysfunction, and hemolytic anemia." | 1.27 | A case of postpartum hemolytic uremic syndrome with severe elevations of liver enzymes. ( Fujii, S; Kanzaki, H; Kariya, M; Matsuura, S; Mori, T; Sagawa, N, 1985) |
| "Coagulation studies revealed disseminated intravascular coagulation and a diagnosis of amniotic fluid embolism was made." | 1.26 | Survival from DIC following amniotic fluid embolism. Successful treatment with a serine proteinase inhibitor; FOY. ( Kawai, M; Kosaki, G; Shimada, Y; Taenaka, N; Yoshiya, I, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumura, T | 1 |
| Aoyama, Y | 1 |
| Ichihara, H | 1 |
| Koh, S | 1 |
| Mugitani, A | 1 |
| Hayakawa, H | 1 |
| Yukioka, K | 1 |
| Kinoshita, D | 1 |
| Nakagawa, M | 1 |
| Yamazaki, N | 1 |
| Fukami, T | 1 |
| Chaen, H | 1 |
| Imura, H | 1 |
| Sudou, K | 1 |
| Eguchi, F | 1 |
| Inoue, N | 1 |
| Ito, T | 1 |
| Akashi, T | 1 |
| Kawabe, K | 1 |
| Oono, T | 1 |
| Gibo, J | 1 |
| Arita, Y | 1 |
| Nawata, H | 1 |
| Funakoshi, A | 1 |
| Maki, M | 3 |
| Soga, K | 1 |
| Gotoh, K | 1 |
| Taenaka, N | 1 |
| Shimada, Y | 1 |
| Kawai, M | 1 |
| Yoshiya, I | 1 |
| Kosaki, G | 1 |
| Kaga, N | 1 |
| Katsuki, Y | 1 |
| Obata, M | 1 |
| Shibutani, Y | 1 |
| Murata, M | 1 |
| Hayakawa, M | 1 |
| Goto, K | 1 |
| Isobe, K | 1 |
| Matuura, T | 1 |
| Hirano, H | 1 |
| Higuchi, M | 1 |
| Terao, T | 1 |
| Ikenoue, T | 1 |
| Takemura, T | 1 |
| Sekiba, K | 1 |
| Shirakawa, K | 1 |
| Soma, H | 1 |
| Takeda, S | 1 |
| Kume, M | 1 |
| Takechi, K | 1 |
| Kasamatsu, T | 1 |
| Yoshida, K | 1 |
| Kinoshita, K | 1 |
| Mizuno, M | 1 |
| Sakamoto, S | 1 |
| Sagawa, N | 1 |
| Kariya, M | 1 |
| Kanzaki, H | 1 |
| Fujii, S | 1 |
| Matsuura, S | 1 |
| Mori, T | 1 |
1 trial available for gabexate and Pregnancy
| Article | Year |
|---|---|
Clinical evaluation of antithrombin III concentrate (BI 6.013) for disseminated intravascular coagulation in obstetrics. Well-controlled multicenter trial.
Topics: Adult; Antithrombin III; Blood Chemical Analysis; Clinical Trials as Topic; Disseminated Intravascul | 1987 |
9 other studies available for gabexate and Pregnancy
| Article | Year |
|---|---|
[Successful treatment with the combination of recombinant human soluble thrombomodulin and gabexate mesilate in three patients with obstetric disseminated intravascular coagulation].
Topics: Abruptio Placentae; Adult; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Female | 2011 |
Acute pancreatitis occurring in the early postpartum period: a case report.
Topics: Abdominal Pain; Acute Disease; Adolescent; Back Pain; Famotidine; Female; Gabexate; Histamine H2 Ant | 2003 |
Acute pancreatitis in the early stages of pregnancy associated with a PSTI gene mutation.
Topics: Abdominal Pain; Acute Disease; Adult; Amino Acid Substitution; Amylases; Carrier Proteins; Diet, Fat | 2004 |
The kinin-forming enzyme system in pregnancy and obstetrical DIC.
Topics: Adult; Animals; Disseminated Intravascular Coagulation; Female; Gabexate; Guanidines; Humans; Kallik | 1983 |
Survival from DIC following amniotic fluid embolism. Successful treatment with a serine proteinase inhibitor; FOY.
Topics: Adult; Blood Transfusion; Disseminated Intravascular Coagulation; Embolism, Amniotic Fluid; Female; | 1981 |
Repeated administration of low-dose lipopolysaccharide induces preterm delivery in mice: a model for human preterm parturition and for assessment of the therapeutic ability of drugs against preterm delivery.
Topics: Animals; Disease Models, Animal; Escherichia coli; Female; Gabexate; Glycoproteins; Humans; Indometh | 1996 |
[Anticoagulant therapy in obstetrical disorders].
Topics: Antithrombin III; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Female; Fetal G | 1990 |
The effect of a serine proteinase inhibitor on DIC in septic abortion.
Topics: Abortion, Septic; Adult; Anticoagulants; Disseminated Intravascular Coagulation; Female; Gabexate; G | 1987 |
A case of postpartum hemolytic uremic syndrome with severe elevations of liver enzymes.
Topics: Adult; Alkaline Phosphatase; Disseminated Intravascular Coagulation; Female; Furosemide; Gabexate; G | 1985 |