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gabexate and Pancreatic Diseases

gabexate has been researched along with Pancreatic Diseases in 6 studies

Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Pancreatic Diseases: Pathological processes of the PANCREAS.

Research Excerpts

ExcerptRelevanceReference
"The aim of the present study was to examine the potential efficacy of camostat mesilate, a protease inhibitor, against dyspepsia associated with non-alcoholic mild pancreatic disease."9.14Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic disease. ( Inami, K; Kubokawa, Y; Matsumura, Y; Sai, JK; Suyama, M; Watanabe, S, 2010)
"A continuous 13-h infusion of gabexate starting 30-90 min before endoscopic cholangiopancreatography (ERCP) can reduce postprocedural pancreatitis, the onset of which is generally observed within the first 6 h after ERCP."9.10Comparison of two dosing regimens of gabexate in the prophylaxis of post-ERCP pancreatitis. ( Cavallini, G; Costamagna, G; Curioni, S; Dragonetti, C; Frulloni, L; Innocenti, P; Macarri, G; Mariani, A; Masci, E; Testoni, PA; Tittobello, A; Uomo, G; Zambelli, S, 2003)
"Camostat has a beneficial effect on pancreatic fibrosis induced by the administration of a SOD inhibitor, which inhibits the proliferation and activation of PSC."7.73Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats. ( Emori, Y; Ichimura, M; Koide, N; Matsumura, N; Mizushima, T; Ochi, K; Shinji, T; Shirahige, A; Tanimoto, M; Tanioka, H, 2005)
"The aim of the present study was to examine the potential efficacy of camostat mesilate, a protease inhibitor, against dyspepsia associated with non-alcoholic mild pancreatic disease."5.14Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic disease. ( Inami, K; Kubokawa, Y; Matsumura, Y; Sai, JK; Suyama, M; Watanabe, S, 2010)
"A continuous 13-h infusion of gabexate starting 30-90 min before endoscopic cholangiopancreatography (ERCP) can reduce postprocedural pancreatitis, the onset of which is generally observed within the first 6 h after ERCP."5.10Comparison of two dosing regimens of gabexate in the prophylaxis of post-ERCP pancreatitis. ( Cavallini, G; Costamagna, G; Curioni, S; Dragonetti, C; Frulloni, L; Innocenti, P; Macarri, G; Mariani, A; Masci, E; Testoni, PA; Tittobello, A; Uomo, G; Zambelli, S, 2003)
"Camostat has a beneficial effect on pancreatic fibrosis induced by the administration of a SOD inhibitor, which inhibits the proliferation and activation of PSC."3.73Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats. ( Emori, Y; Ichimura, M; Koide, N; Matsumura, N; Mizushima, T; Ochi, K; Shinji, T; Shirahige, A; Tanimoto, M; Tanioka, H, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sai, JK1
Suyama, M1
Kubokawa, Y1
Matsumura, Y1
Inami, K1
Watanabe, S1
Manfredi, R1
Calza, L1
Chiodo, F1
Masci, E1
Cavallini, G1
Mariani, A1
Frulloni, L1
Testoni, PA1
Curioni, S1
Tittobello, A1
Uomo, G1
Costamagna, G1
Zambelli, S1
Macarri, G1
Innocenti, P1
Dragonetti, C1
Emori, Y1
Mizushima, T1
Matsumura, N1
Ochi, K1
Tanioka, H1
Shirahige, A1
Ichimura, M1
Shinji, T1
Koide, N1
Tanimoto, M1
Watanapa, P1
Williamson, RC1
Oishi, T1
Nakagawa, M1
Bamba, T1
Hosoda, S1

Reviews

1 review available for gabexate and Pancreatic Diseases

ArticleYear
Experimental pancreatic hyperplasia and neoplasia: effects of dietary and surgical manipulation.
    British journal of cancer, 1993, Volume: 67, Issue:5

    Topics: Animals; Cricetinae; Diet; Disease Models, Animal; Energy Intake; Esters; Flour; Gabexate; Glycine m

1993

Trials

2 trials available for gabexate and Pancreatic Diseases

ArticleYear
Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic disease.
    Journal of gastroenterology, 2010, Volume: 45, Issue:3

    Topics: Abdominal Pain; Adult; Aged; Dyspepsia; Endosonography; Esters; Female; Gabexate; Guanidines; Humans

2010
Comparison of two dosing regimens of gabexate in the prophylaxis of post-ERCP pancreatitis.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Biliary Tract Diseases; Cholangiopancreat

2003

Other Studies

3 other studies available for gabexate and Pancreatic Diseases

ArticleYear
Gabexate mesilate and/or octreotide in human immunodeficiency virus-associated pancreatic abnormalities.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:10

    Topics: Adult; Case-Control Studies; Drug Combinations; Female; Gabexate; HIV Infections; Humans; Male; Octr

2002
Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:6

    Topics: Administration, Oral; Animals; Disease Models, Animal; Ditiocarb; Drug Administration Schedule; Este

2005
[Study on the trophic effect of camostate mesilate on ethionine-induced pancreatic injury rat].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1989, Volume: 86, Issue:5

    Topics: Administration, Oral; Amylases; Animals; Cholecystokinin; Esters; Ethionine; Gabexate; Guanidines; I

1989