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gabexate and Neuromuscular Blockade

gabexate has been researched along with Neuromuscular Blockade in 1 studies

Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Neuromuscular Blockade: The intentional interruption of transmission at the NEUROMUSCULAR JUNCTION by external agents, usually neuromuscular blocking agents. It is distinguished from NERVE BLOCK in which nerve conduction (NEURAL CONDUCTION) is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anesthesia but is grouped here with anesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here.

Research Excerpts

ExcerptRelevanceReference
"To test the hypothesis that gabexate mesilate, a protease inihibitor, hastens recovery from neuromuscular blockade, we examined the effect of gabexate mesilate on the recovery of vecuronium-induced neuromuscular blockade in anaesthetized patients in a double-blind, randomized fashion."9.11Gabexate mesilate hastens recovery from vecuronium-induced neuromuscular blockade. ( Akatu, M; Hattori, H; Murakawa, M; Nakajima, H; Saitoh, Y; Sanbe, N, 2005)
"To test the hypothesis that gabexate mesilate, a protease inihibitor, hastens recovery from neuromuscular blockade, we examined the effect of gabexate mesilate on the recovery of vecuronium-induced neuromuscular blockade in anaesthetized patients in a double-blind, randomized fashion."5.11Gabexate mesilate hastens recovery from vecuronium-induced neuromuscular blockade. ( Akatu, M; Hattori, H; Murakawa, M; Nakajima, H; Saitoh, Y; Sanbe, N, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hattori, H1
Saitoh, Y1
Nakajima, H1
Sanbe, N1
Akatu, M1
Murakawa, M1

Trials

1 trial available for gabexate and Neuromuscular Blockade

ArticleYear
Gabexate mesilate hastens recovery from vecuronium-induced neuromuscular blockade.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:1

    Topics: Adult; Aged; Anesthesia; Anesthesia Recovery Period; Electric Stimulation; Female; Gabexate; Hemodyn

2005