gabexate has been researched along with Nephrotic Syndrome in 3 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asami, T | 1 |
| Ohsawa, S | 1 |
| Tomisawa, S | 1 |
| Hashimoto, K | 1 |
| Toyabe, S | 1 |
| Sakai, K | 1 |
| Terada, H | 1 |
| Makino, H | 1 |
| Onbe, T | 1 |
| Kumagai, I | 1 |
| Murakami, K | 1 |
| Ota, Z | 1 |
3 other studies available for gabexate and Nephrotic Syndrome
| Article | Year |
|---|---|
Glomerular deposition of alpha 2-macroglobulin in a child with steroid refractory nephrotic syndrome.
Topics: alpha-Macroglobulins; Child, Preschool; Esters; Gabexate; Guanidines; Humans; Kidney Glomerulus; Mal | 1992 |
[Changes in platelets, coagulation and fibrinolysis in patients with chronic kidney diseases and hemodialysis].
Topics: Benzamidines; Blood Coagulation; Blood Platelets; Epoprostenol; Fibrinolysis; Gabexate; Guanidines; | 1992 |
A proteinase inhibitor reduces proteinuria in nephrotic syndrome.
Topics: Esters; Gabexate; Guanidines; Humans; Nephrotic Syndrome; Protease Inhibitors; Proteinuria | 1991 |