gabexate has been researched along with Necrosis in 7 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In mongrel dogs with induced pancreatitis we studied the effects of the nonspecific phospholipase A2-inhibitors chlorpromazine, gabexate mesilate and CaNa2EDTA on the course of pancreatogenic shock and the intrapancreatic lysolecithin production." | 3.67 | [Phospholipase A2 inhibitors in hemorrhagic-necrotizing pancreatitis. Animal experiment evaluation of a new treatment concept]. ( Alles, JU; Kahle, M; Klein, U; König, W; Martin, U, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aki, T | 2 |
| Egashira, N | 2 |
| Yamauchi, Y | 2 |
| Hama, M | 2 |
| Yano, T | 2 |
| Itoh, Y | 2 |
| Yamada, T | 1 |
| Oishi, R | 2 |
| Yuasa, T | 1 |
| Taniguchi, Y | 1 |
| Yamada, E | 1 |
| Inachi, S | 1 |
| Shimizu, M | 1 |
| Bassi, C | 1 |
| Benetti, L | 1 |
| Girelli, R | 1 |
| Falconi, M | 1 |
| Nifosí, F | 1 |
| Coviello, G | 1 |
| Cavallini, G | 1 |
| Vesentini, S | 1 |
| Dragonetti, C | 1 |
| Pederzoli, P | 1 |
| Kahle, M | 2 |
| König, H | 1 |
| Filler, RD | 1 |
| Sasaki, S | 1 |
| Klein, U | 1 |
| König, W | 1 |
| Martin, U | 1 |
| Alles, JU | 1 |
1 review available for gabexate and Necrosis
| Article | Year |
|---|---|
Severe cutaneous and venous damage after DIC therapy.
Topics: Aged; Anticoagulants; Disseminated Intravascular Coagulation; Female; Gabexate; Humans; Necrosis; Sa | 1997 |
6 other studies available for gabexate and Necrosis
| Article | Year |
|---|---|
Protective effects of amino acids against gabexate mesilate-induced cell injury in porcine aorta endothelial cells.
Topics: Amino Acids; Animals; Aorta; Endothelium, Vascular; Gabexate; Glycine; Necrosis; Propidium; Receptor | 2008 |
Characteristics of gabexate mesilate-induced cell injury in porcine aorta endothelial cells.
Topics: Adenosine Triphosphate; Animals; Aorta; Apoptosis; Benzamidines; Calcium; Cell Membrane; Cell Surviv | 2008 |
Early graft injuries after pancreatic transplantation in syngeneic rats. Cytoprotective effects of gabexate-mesilate.
Topics: Analysis of Variance; Animals; Edema; Gabexate; Graft Survival; Necrosis; Organ Preservation; Pancre | 1991 |
Lysolecithin concentration in pancreatic tissue during therapy with phospholipase A2-inhibitors in acute necrotizing pancreatitis.
Topics: Acute Disease; Animals; Chlorpromazine; Dogs; Dose-Response Relationship, Drug; Edetic Acid; Female; | 1989 |
[Experimental study on renal protection against damage in kidneys subjected warm ischemia--protective effect of FOY, SOD, and PEG-SOD on ischemic acute renal failure].
Topics: Acute Kidney Injury; Animals; Gabexate; Guanidines; Ischemia; Kidney; Kidney Tubules; Necrosis; Poly | 1989 |
[Phospholipase A2 inhibitors in hemorrhagic-necrotizing pancreatitis. Animal experiment evaluation of a new treatment concept].
Topics: Acute Disease; Animals; Chlorpromazine; Dogs; Edetic Acid; Female; Gabexate; Guanidines; Hemodynamic | 1985 |