gabexate has been researched along with Liver Failure, Acute in 2 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study examined the effects of GM on hepatic encephalopathy in rats with acute and chronic liver failure." | 5.36 | Lack of therapeutic effects of gabexate mesilate on the hepatic encephalopathy in rats with acute and chronic hepatic failure. ( Chan, CY; Chang, CC; Hsu, CY; Huang, HC; Huo, TI; Lee, FY; Lee, SD; Lin, HC; Teng, TH; Wang, SS, 2010) |
| "A case of disseminated intravascular coagulation (DIC) in a patient with systemic lupus erythematosus (SLE) with acute liver dysfunction is described." | 2.38 | Disseminated intravascular coagulation in lupus erythematosus with acute liver damage. ( Kaneda, S; Sano, M; Shimamoto, Y; Tsunada, S; Yamaguchi, M; Yamamoto, K, 1992) |
| "This study examined the effects of GM on hepatic encephalopathy in rats with acute and chronic liver failure." | 1.36 | Lack of therapeutic effects of gabexate mesilate on the hepatic encephalopathy in rats with acute and chronic hepatic failure. ( Chan, CY; Chang, CC; Hsu, CY; Huang, HC; Huo, TI; Lee, FY; Lee, SD; Lin, HC; Teng, TH; Wang, SS, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsu, CY | 1 |
| Lee, FY | 1 |
| Huo, TI | 1 |
| Chan, CY | 1 |
| Huang, HC | 1 |
| Lin, HC | 1 |
| Chang, CC | 1 |
| Teng, TH | 1 |
| Wang, SS | 1 |
| Lee, SD | 1 |
| Shimamoto, Y | 1 |
| Sano, M | 1 |
| Kaneda, S | 1 |
| Tsunada, S | 1 |
| Yamamoto, K | 1 |
| Yamaguchi, M | 1 |
1 review available for gabexate and Liver Failure, Acute
| Article | Year |
|---|---|
Disseminated intravascular coagulation in lupus erythematosus with acute liver damage.
Topics: Adult; Antithrombin III; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Gabexate | 1992 |
1 other study available for gabexate and Liver Failure, Acute
| Article | Year |
|---|---|
Lack of therapeutic effects of gabexate mesilate on the hepatic encephalopathy in rats with acute and chronic hepatic failure.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Blood Pressure; Chronic Disease; Common Bile Duct; Di | 2010 |