gabexate has been researched along with Kidney Failure, Chronic in 3 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The number of the chronic renal failure (CRF) patients is increasing explosively." | 1.38 | Effect of a serine protease inhibitor on the progression of chronic renal failure. ( Adachi, M; Hayata, M; Kakizoe, Y; Kitamura, K; Miyoshi, T; Mizumoto, T; Morinaga, J; Onoue, T; Sakai, Y; Shiraishi, N; Tomita, K; Uchimura, K; Ueda, M; Yamazoe, R, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayata, M | 1 |
| Kakizoe, Y | 1 |
| Uchimura, K | 1 |
| Morinaga, J | 1 |
| Yamazoe, R | 1 |
| Mizumoto, T | 1 |
| Onoue, T | 1 |
| Ueda, M | 1 |
| Shiraishi, N | 1 |
| Adachi, M | 1 |
| Miyoshi, T | 1 |
| Sakai, Y | 1 |
| Tomita, K | 1 |
| Kitamura, K | 1 |
| Kinugasa, E | 1 |
| Makita, T | 1 |
| Akizawa, T | 1 |
| Koshikawa, S | 1 |
| Terada, H | 1 |
3 other studies available for gabexate and Kidney Failure, Chronic
| Article | Year |
|---|---|
Effect of a serine protease inhibitor on the progression of chronic renal failure.
Topics: Animals; Creatinine; Disease Progression; Esters; Gabexate; Guanidines; Kidney; Kidney Failure, Chro | 2012 |
[Treatment of uremic patients at high bleeding risk].
Topics: Benzamidines; Blood Transfusion; Deamino Arginine Vasopressin; Gabexate; Guanidines; Hemorrhage; Hep | 1992 |
[Changes in platelets, coagulation and fibrinolysis in patients with chronic kidney diseases and hemodialysis].
Topics: Benzamidines; Blood Coagulation; Blood Platelets; Epoprostenol; Fibrinolysis; Gabexate; Guanidines; | 1992 |