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gabexate and Ischemia

gabexate has been researched along with Ischemia in 6 studies

Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"To assess the effects of gabexate mesilate (FOY), a protease inhibitor, on a canine model of pulmonary ischemia-reperfusion injury."7.70Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs. ( Chen, JS; Kuo, SH; Lee, YC; Lin-Shiau, SY; Luh, SP; Shau, WY; Tsai, CC, 1999)
"To assess the effects of gabexate mesilate (FOY), a protease inhibitor, on a canine model of pulmonary ischemia-reperfusion injury."3.70Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs. ( Chen, JS; Kuo, SH; Lee, YC; Lin-Shiau, SY; Luh, SP; Shau, WY; Tsai, CC, 1999)
" GM was administered intravenously at a dosage of 2."2.72Evaluation of a protease inhibitor in the prevention of ischemia and reperfusion injury in hepatectomy under intermittent Pringle maneuver. ( Chun, BY; Chung, HJ; Hwang, YJ; Kim, YI; Lee, JW; Lee, YJ; Song, KE, 2006)
"Reperfusion injury is a large problem in the early stage after lung transplantation."1.29The effect of protease inhibitor on reperfusion injury after unilateral pulmonary ischemia. ( Harada, Y; Horiguchi, T, 1993)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, YI1
Chung, HJ1
Song, KE1
Hwang, YJ1
Lee, JW1
Lee, YJ1
Chun, BY1
Pflüger, H1
Maier, M1
Binder, BR1
Horiguchi, T1
Harada, Y1
Hossain, MA1
Hamamoto, I1
Okano, K1
Okada, S1
Wakabayashi, H1
Maeba, T1
Maeta, H1
Luh, SP1
Tsai, CC1
Shau, WY1
Chen, JS1
Kuo, SH1
Lin-Shiau, SY1
Lee, YC1
Sasaki, S1

Trials

1 trial available for gabexate and Ischemia

ArticleYear
Evaluation of a protease inhibitor in the prevention of ischemia and reperfusion injury in hepatectomy under intermittent Pringle maneuver.
    American journal of surgery, 2006, Volume: 191, Issue:1

    Topics: Adult; Female; Gabexate; Hepatectomy; Humans; Ischemia; Liver; Liver Diseases; Male; Middle Aged; Pr

2006

Other Studies

5 other studies available for gabexate and Ischemia

ArticleYear
Effects of antiproteases (aprotinin and gabexate-mesilate) on the postischemic vascular response of the kidney.
    Urologia internationalis, 1983, Volume: 38, Issue:3

    Topics: Animals; Aprotinin; Gabexate; Guanidines; Ischemia; Kidney; Kidney Cortex; Rabbits; Vascular Resista

1983
The effect of protease inhibitor on reperfusion injury after unilateral pulmonary ischemia.
    Transplantation, 1993, Volume: 55, Issue:2

    Topics: Animals; Dogs; Free Radical Scavengers; Gabexate; Glycoproteins; Ischemia; Lung; Neutrophils; Radiog

1993
Ameliorative effect of gabexate mesilate on the disturbed microcirculation following prolonged cold ischemia of the liver.
    Transplantation proceedings, 1996, Volume: 28, Issue:1

    Topics: Adenosine; Allopurinol; Analysis of Variance; Animals; Anticoagulants; Bile; Cold Temperature; Gabex

1996
Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs.
    The Journal of surgical research, 1999, Volume: 87, Issue:2

    Topics: Animals; Bronchoalveolar Lavage Fluid; Dogs; Gabexate; Hemodynamics; Ischemia; Lung; Neutrophils; Pe

1999
[Experimental study on renal protection against damage in kidneys subjected warm ischemia--protective effect of FOY, SOD, and PEG-SOD on ischemic acute renal failure].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1989, Volume: 64, Issue:4

    Topics: Acute Kidney Injury; Animals; Gabexate; Guanidines; Ischemia; Kidney; Kidney Tubules; Necrosis; Poly

1989