gabexate has been researched along with Ischemia in 6 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the effects of gabexate mesilate (FOY), a protease inhibitor, on a canine model of pulmonary ischemia-reperfusion injury." | 7.70 | Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs. ( Chen, JS; Kuo, SH; Lee, YC; Lin-Shiau, SY; Luh, SP; Shau, WY; Tsai, CC, 1999) |
| "To assess the effects of gabexate mesilate (FOY), a protease inhibitor, on a canine model of pulmonary ischemia-reperfusion injury." | 3.70 | Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs. ( Chen, JS; Kuo, SH; Lee, YC; Lin-Shiau, SY; Luh, SP; Shau, WY; Tsai, CC, 1999) |
| " GM was administered intravenously at a dosage of 2." | 2.72 | Evaluation of a protease inhibitor in the prevention of ischemia and reperfusion injury in hepatectomy under intermittent Pringle maneuver. ( Chun, BY; Chung, HJ; Hwang, YJ; Kim, YI; Lee, JW; Lee, YJ; Song, KE, 2006) |
| "Reperfusion injury is a large problem in the early stage after lung transplantation." | 1.29 | The effect of protease inhibitor on reperfusion injury after unilateral pulmonary ischemia. ( Harada, Y; Horiguchi, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, YI | 1 |
| Chung, HJ | 1 |
| Song, KE | 1 |
| Hwang, YJ | 1 |
| Lee, JW | 1 |
| Lee, YJ | 1 |
| Chun, BY | 1 |
| Pflüger, H | 1 |
| Maier, M | 1 |
| Binder, BR | 1 |
| Horiguchi, T | 1 |
| Harada, Y | 1 |
| Hossain, MA | 1 |
| Hamamoto, I | 1 |
| Okano, K | 1 |
| Okada, S | 1 |
| Wakabayashi, H | 1 |
| Maeba, T | 1 |
| Maeta, H | 1 |
| Luh, SP | 1 |
| Tsai, CC | 1 |
| Shau, WY | 1 |
| Chen, JS | 1 |
| Kuo, SH | 1 |
| Lin-Shiau, SY | 1 |
| Lee, YC | 1 |
| Sasaki, S | 1 |
1 trial available for gabexate and Ischemia
| Article | Year |
|---|---|
Evaluation of a protease inhibitor in the prevention of ischemia and reperfusion injury in hepatectomy under intermittent Pringle maneuver.
Topics: Adult; Female; Gabexate; Hepatectomy; Humans; Ischemia; Liver; Liver Diseases; Male; Middle Aged; Pr | 2006 |
5 other studies available for gabexate and Ischemia
| Article | Year |
|---|---|
Effects of antiproteases (aprotinin and gabexate-mesilate) on the postischemic vascular response of the kidney.
Topics: Animals; Aprotinin; Gabexate; Guanidines; Ischemia; Kidney; Kidney Cortex; Rabbits; Vascular Resista | 1983 |
The effect of protease inhibitor on reperfusion injury after unilateral pulmonary ischemia.
Topics: Animals; Dogs; Free Radical Scavengers; Gabexate; Glycoproteins; Ischemia; Lung; Neutrophils; Radiog | 1993 |
Ameliorative effect of gabexate mesilate on the disturbed microcirculation following prolonged cold ischemia of the liver.
Topics: Adenosine; Allopurinol; Analysis of Variance; Animals; Anticoagulants; Bile; Cold Temperature; Gabex | 1996 |
Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs.
Topics: Animals; Bronchoalveolar Lavage Fluid; Dogs; Gabexate; Hemodynamics; Ischemia; Lung; Neutrophils; Pe | 1999 |
[Experimental study on renal protection against damage in kidneys subjected warm ischemia--protective effect of FOY, SOD, and PEG-SOD on ischemic acute renal failure].
Topics: Acute Kidney Injury; Animals; Gabexate; Guanidines; Ischemia; Kidney; Kidney Tubules; Necrosis; Poly | 1989 |