gabexate has been researched along with Inflammatory Response Syndrome, Systemic in 3 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of continuous regional arterial infusion therapy (CRAI) with gabexate mesilate and antibiotics for severe acute pancreatitis (SAP)." | 7.74 | Continuous regional arterial infusion therapy with gabexate mesilate for severe acute pancreatitis. ( Akashi, T; Arita, Y; Furukawa, M; Igarashi, H; Ino, Y; Ito, T; Kawabe, K; Kimura, T; Miyahara, T; Ogoshi, K; Oono, T; Ouchi, J; Takayanagi, R, 2008) |
| "Reduction of systemic inflammatory response syndrome duration after esophagectomy by the continuous administration of gabexate mesilate started before operation may be through the suppression of TNF-alpha production capacity and Mac-1 expression on monocytes immediately after operation, and to suppression of increase in serum IL-6 level." | 5.09 | Effects of a protease inhibitor on reduction of surgical stress in esophagectomy. ( Aosasa, S; Mochizuki, H; Ono, S, 1999) |
| "To evaluate the efficacy of continuous regional arterial infusion therapy (CRAI) with gabexate mesilate and antibiotics for severe acute pancreatitis (SAP)." | 3.74 | Continuous regional arterial infusion therapy with gabexate mesilate for severe acute pancreatitis. ( Akashi, T; Arita, Y; Furukawa, M; Igarashi, H; Ino, Y; Ito, T; Kawabe, K; Kimura, T; Miyahara, T; Ogoshi, K; Oono, T; Ouchi, J; Takayanagi, R, 2008) |
| "Whereas in DIC associated with trauma, since balance between coagulation and fibrinolysis collapses drastically in a short period, both anticoagulantion therapy and antifibrinolytic therapy can be utilized depending on clinical conditions." | 2.53 | [Anti DIC therapy]. ( Sakamoto, Y; Yahata, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yahata, M | 1 |
| Sakamoto, Y | 1 |
| Ino, Y | 1 |
| Arita, Y | 1 |
| Akashi, T | 1 |
| Kimura, T | 1 |
| Igarashi, H | 1 |
| Oono, T | 1 |
| Furukawa, M | 1 |
| Kawabe, K | 1 |
| Ogoshi, K | 1 |
| Ouchi, J | 1 |
| Miyahara, T | 1 |
| Takayanagi, R | 1 |
| Ito, T | 1 |
| Ono, S | 1 |
| Aosasa, S | 1 |
| Mochizuki, H | 1 |
1 review available for gabexate and Inflammatory Response Syndrome, Systemic
| Article | Year |
|---|---|
[Anti DIC therapy].
Topics: Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzamidines; Disseminated Intravascular Coa | 2016 |
1 trial available for gabexate and Inflammatory Response Syndrome, Systemic
| Article | Year |
|---|---|
Effects of a protease inhibitor on reduction of surgical stress in esophagectomy.
Topics: Aged; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administ | 1999 |
1 other study available for gabexate and Inflammatory Response Syndrome, Systemic
| Article | Year |
|---|---|
Continuous regional arterial infusion therapy with gabexate mesilate for severe acute pancreatitis.
Topics: Abdominal Pain; Acute Disease; Adult; Aged; Anti-Bacterial Agents; C-Reactive Protein; Drug Therapy, | 2008 |