gabexate has been researched along with Inflammation in 6 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, the effects of the serine protease inhibitors nafamostat mesilate (FUT), gabexate mesilate (FOY), and ulinastatin (UTI) on a long-term challenged mouse model of chronic asthma are unclear." | 3.80 | The effect of serine protease inhibitors on airway inflammation in a chronic allergen-induced asthma mouse model. ( Chao, YP; Chiang, CJ; Kao, ST; Lin, CC; Lin, J; Lin, LJ; Wang, SD, 2014) |
| "Papaverine, which is a smooth muscle relaxant, also acted as an antagonist." | 1.29 | A possible approach to the suppression of side effects induced by PGE1. ( Kubota, M; Nakabou, Y; Ojima, M; Takada, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, CC | 1 |
| Lin, LJ | 1 |
| Wang, SD | 1 |
| Chiang, CJ | 1 |
| Chao, YP | 1 |
| Lin, J | 1 |
| Kao, ST | 1 |
| Ammendola, M | 1 |
| Leporini, C | 1 |
| Marech, I | 1 |
| Gadaleta, CD | 1 |
| Scognamillo, G | 1 |
| Sacco, R | 1 |
| Sammarco, G | 1 |
| De Sarro, G | 1 |
| Russo, E | 1 |
| Ranieri, G | 1 |
| Tokodai, K | 1 |
| Goto, M | 1 |
| Inagaki, A | 1 |
| Imura, T | 1 |
| Satomi, S | 1 |
| Daniluk, J | 1 |
| Liu, Y | 1 |
| Deng, D | 1 |
| Chu, J | 1 |
| Huang, H | 1 |
| Gaiser, S | 1 |
| Cruz-Monserrate, Z | 1 |
| Wang, H | 1 |
| Ji, B | 1 |
| Logsdon, CD | 1 |
| Nakabou, Y | 1 |
| Kubota, M | 1 |
| Takada, K | 1 |
| Ojima, M | 1 |
| Mitsuoka, H | 1 |
| Kistler, EB | 1 |
| Schmid-Schönbein, GW | 1 |
1 review available for gabexate and Inflammation
| Article | Year |
|---|---|
Targeting mast cells tryptase in tumor microenvironment: a potential antiangiogenetic strategy.
Topics: Angiogenesis Inhibitors; Cell Proliferation; Gabexate; Humans; Inflammation; Mast Cells; Neoplasms; | 2014 |
5 other studies available for gabexate and Inflammation
| Article | Year |
|---|---|
The effect of serine protease inhibitors on airway inflammation in a chronic allergen-induced asthma mouse model.
Topics: Allergens; Animals; Asthma; Benzamidines; Disease Models, Animal; Gabexate; Glycoproteins; Guanidine | 2014 |
Effect of synthetic protease inhibitor gabexate mesilate on attenuation of coagulant activity and cytokine release in a rat model of islet transplantation.
Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Cell Transplantation; Coagulants; Cytokines; Gabe | 2011 |
An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Transformation, Neoplastic; Ceruletide; Cyclooxygenase 2 | 2012 |
A possible approach to the suppression of side effects induced by PGE1.
Topics: Alprostadil; Animals; Atropine; Capillary Permeability; Gabexate; Guanidines; Guinea Pigs; Histamine | 1995 |
Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock.
Topics: Animals; Blood Pressure; Endopeptidases; Esters; Gabexate; Guanidines; Humans; In Vitro Techniques; | 2002 |