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gabexate and Esophagitis, Reflux

gabexate has been researched along with Esophagitis, Reflux in 5 studies

Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Research Excerpts

ExcerptRelevanceReference
"The pathogenesis of reflux esophagitis is not well understood and remains controversial."2.71Oral trypsin inhibitor can improve reflux esophagitis after distal gastrectomy concomitant with decreased trypsin activity. ( Fujii, H; Kamiyasu, K; Kono, K; Sugai, H; Takahashi, A; Teramatsu, M; Umekawa, T; Yano, T, 2005)
"Camostat mesilate was given for prevention and cure."1.30Effect of trypsin inhibitor on reflux oesophagitis after total gastrectomy in rats. ( Chen, C; Hatori, S; Imada, T; Rino, Y; Shiozawa, M, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kono, K1
Takahashi, A1
Sugai, H1
Umekawa, T1
Yano, T1
Kamiyasu, K3
Teramatsu, M1
Fujii, H1
Imada, T1
Chen, C1
Hatori, S1
Shiozawa, M1
Rino, Y1
Moriya, S1
Omura, N1
Kashiwagi, H1
Inagaki, Y1
Aoki, T1
Inoshiri, S2
Omawari, N2
Okegawa, T2
Kawasaki, A2
Awata, H1
Doi, A1
Shinomiya, K1
Tanaka, M1
Suzuki, Y1

Trials

1 trial available for gabexate and Esophagitis, Reflux

ArticleYear
Oral trypsin inhibitor can improve reflux esophagitis after distal gastrectomy concomitant with decreased trypsin activity.
    American journal of surgery, 2005, Volume: 190, Issue:3

    Topics: Administration, Oral; Aged; Esophagitis, Peptic; Esters; Female; Gabexate; Gastrectomy; Gastroentero

2005

Other Studies

4 other studies available for gabexate and Esophagitis, Reflux

ArticleYear
Effect of trypsin inhibitor on reflux oesophagitis after total gastrectomy in rats.
    The European journal of surgery = Acta chirurgica, 1999, Volume: 165, Issue:11

    Topics: Animals; Antimetabolites; Apoptosis; Bromodeoxyuridine; Cell Division; Esophagitis, Peptic; Esters;

1999
[Treatment of peptic ulcer and reflux esophagitis with enzyme inhibitors].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Adult; Aged; Esophagitis, Peptic; Esters; Female; Gabexate; Gastric Acid; Guanidines; Humans; Omepra

1991
[Effect of FOY-305 on post-operative reflux esophagitis in rats (II). Analysis of mechanism in the pathogenesis of reflux esophagitis after total gastrectomy in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:5

    Topics: Animals; Bile Acids and Salts; Depression, Chemical; Esophagitis, Peptic; Esophagus; Esters; Gabexat

1991
[Effects of FOY-305 on post-operative reflux esophagitis in rats (I). Effects of FOY-305 on reflux esophagitis after total gastrectomy in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:5

    Topics: Alginates; Animals; Body Weight; Cimetidine; Disease Models, Animal; Esophagitis, Peptic; Esters; Ga

1991