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gabexate and Esophageal Neoplasms

gabexate has been researched along with Esophageal Neoplasms in 4 studies

Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.

Research Excerpts

ExcerptRelevanceReference
"Reduction of systemic inflammatory response syndrome duration after esophagectomy by the continuous administration of gabexate mesilate started before operation may be through the suppression of TNF-alpha production capacity and Mac-1 expression on monocytes immediately after operation, and to suppression of increase in serum IL-6 level."5.09Effects of a protease inhibitor on reduction of surgical stress in esophagectomy. ( Aosasa, S; Mochizuki, H; Ono, S, 1999)
"Sixty-one patients operated for esophageal cancer from 1996 to 2000 were treated postoperatively with low dose dopamine (300 microg/kg/h), gabexate mesilate (80 mg/h), and ulinastatin (300 000 unit/day) as a study group."1.33Use of low dose dopamine, gabexate mesilate and ulinastatin reduces the water balance and pulmonary complication in thoracic esophagectomy patients. ( Fujii, Y; Ishiguro, H; Kimura, M; Kuwabara, Y; Sato, A; Shinoda, N, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sato, A1
Kuwabara, Y1
Shinoda, N1
Kimura, M1
Ishiguro, H1
Fujii, Y1
Ono, S1
Aosasa, S1
Mochizuki, H1
Usuba, A1
Motoki, R1
Koizumi, Y1
Oishi, A1
Endo, Y1
Konno, O1
Inoue, H1
Kabuto, T1
Furukawa, H1
Imaoka, S1
Iwanaga, T1

Trials

1 trial available for gabexate and Esophageal Neoplasms

ArticleYear
Effects of a protease inhibitor on reduction of surgical stress in esophagectomy.
    American journal of surgery, 1999, Volume: 177, Issue:1

    Topics: Aged; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administ

1999

Other Studies

3 other studies available for gabexate and Esophageal Neoplasms

ArticleYear
Use of low dose dopamine, gabexate mesilate and ulinastatin reduces the water balance and pulmonary complication in thoracic esophagectomy patients.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2005, Volume: 18, Issue:3

    Topics: Carcinoma, Squamous Cell; Dopamine; Esophageal Neoplasms; Esophagectomy; Gabexate; Glycoproteins; Hu

2005
[Effects of the synthetic proteinase inhibitor, FOY, on hypercoagulability after surgery for esophageal carcinoma].
    Nihon Geka Gakkai zasshi, 1990, Volume: 91, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Blood Coagulation; Esophageal Neoplasms; Female; Fib

1990
[Therapy of postoperative hypoxia following mediastinal lymph node excision of esophageal cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 1987, Volume: 45, Issue:2

    Topics: Aged; Animals; Dogs; Esophageal Neoplasms; Gabexate; Guanidines; Humans; Hypoxia; Lymph Node Excisio

1987