gabexate has been researched along with Endotoxemia in 1 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Several studies have reported that gabexate mesilate, a synthetic inhibitor of trypsin-like serine protease, protects tissues/organs against injury in the models of endotoxemia." | 7.81 | Effects of gabexate mesilate on coagulopathy and organ dysfunction in rats with endotoxemia: a potential use of thrombelastography in endotoxin-induced sepsis. ( Ding, C; Ka, SM; Liao, MH; Liaw, WJ; Tsai, HJ; Tsao, CM; Wu, CC, 2015) |
| " Several studies have reported that gabexate mesilate, a synthetic inhibitor of trypsin-like serine protease, protects tissues/organs against injury in the models of endotoxemia." | 3.81 | Effects of gabexate mesilate on coagulopathy and organ dysfunction in rats with endotoxemia: a potential use of thrombelastography in endotoxin-induced sepsis. ( Ding, C; Ka, SM; Liao, MH; Liaw, WJ; Tsai, HJ; Tsao, CM; Wu, CC, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsai, HJ | 1 |
| Ding, C | 1 |
| Tsao, CM | 1 |
| Liao, MH | 1 |
| Ka, SM | 1 |
| Liaw, WJ | 1 |
| Wu, CC | 1 |
1 other study available for gabexate and Endotoxemia
| Article | Year |
|---|---|
Effects of gabexate mesilate on coagulopathy and organ dysfunction in rats with endotoxemia: a potential use of thrombelastography in endotoxin-induced sepsis.
Topics: Animals; Anticoagulants; Blood Coagulation Disorders; Endotoxemia; Gabexate; Lipopolysaccharides; Ma | 2015 |