Page last updated: 2024-10-27

gabexate and Disseminated Intravascular Coagulation

gabexate has been researched along with Disseminated Intravascular Coagulation in 86 studies

Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Disseminated Intravascular Coagulation: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.

Research Excerpts

ExcerptRelevanceReference
"We hypothesized that antithrombin is more effective for disseminated intravascular coagulation (DIC) than is gabexate mesilate, which is a protease inhibitor, suggested from the previous studies."9.16Effects of antithrombin and gabexate mesilate on disseminated intravascular coagulation: a preliminary study. ( Kohno, Y; Koishi, K; Nishiyama, T, 2012)
"Gabexate mesilate (GM) is a promising anticoagulation treatment for disseminated intravascular coagulation (DIC)."9.11Efficacy of gabexate mesilate on disseminated intravascular coagulation as a complication of infection developing after abdominal surgery. ( Chen, HM; Chen, JC; Chen, MF; Chiu, DF; Hsu, JT; Huang, CJ; Hwang, TL; Jan, YY, 2004)
"The effects of gabexate mesilate on disseminated intravascular coagulation (DIC) accompanying neoplastic diseases or severe infections in ten patients were investigated and compared with those of heparin therapy in ten other patients with DIC."9.06Gabexate as a therapy for disseminated intravascular coagulation. ( Adachi, M; Soejima, R; Umeki, S; Watanabe, M; Yaji, S, 1988)
"We evaluated clinical outcomes of disseminated intravascular coagulation (DIC) in patients with hematological malignancies treated with synthetic protease inhibitors (SPIs) and compared the effects of gabexate mesilate (FOY) and nafamostat mesilate (FUT)."7.91Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies. ( Ashizawa, M; Fujiwara, SI; Hatano, K; Ikeda, T; Ito, S; Kanda, Y; Kawaguchi, SI; Kawasaki, Y; Mashima, K; Minakata, D; Morita, K; Muroi, K; Nagayama, T; Nakano, H; Ochi, SI; Oh, I; Ohmine, K; Ohmori, T; Sato, K; Sugimoto, M; Toda, Y; Umino, K; Yamamoto, C; Yamasaki, R, 2019)
" We retrospectively evaluated and compared the efficacies of rhTM and gabexate mesilate (GM) in patients diagnosed with sepsis-induced DIC."7.80A retrospective comparative study of recombinant human thrombomodulin and gabexate mesilate in sepsis-induced disseminated intravascular coagulation patients. ( Imamura, Y; Izumikawa, K; Kohno, S; Matsuo, N; Miyazaki, T; Nakamura, S; Sawai, T; Suyama, N; Takazono, T; Yanagihara, K; Yoshioka, S, 2014)
"25 mg/kg/hr for 4 hr) was shown to induce disseminated intravascular coagulation (DIC) in rats, which resulted in hypofibrinogenemia, prolongation of prothrombin (PT) and partial thromboplastin time (PTT), thrombocytopenia, and elevated levels of fibrinogen/fibrin degradation products (FDP)."7.68Effect of a selective PAF antagonist SM-10661 ((+/-)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one HCl) on experimental disseminated intravascular coagulation (DIC). ( Imanishi, N; Komuro, Y; Morooka, S, 1991)
"We describe a case of thoracic aortic aneurysm complicated by chronic disseminated intravascular coagulation (DIC)."5.31[Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin]. ( Fukuda, N; Nakamori, Y; Oeda, E; Sato, Y; Shimohakamada, Y; Shinohara, K; Takahashi, T; Tominaga, T, 2002)
"He was diagnosed as having chronic disseminated intravascular coagulation (DIC) complicated by a thoracoabdominal aortic aneurysm, and was treated with heparin sodium and a protease inhibitor."5.31[Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm]. ( Amano, I; Morii, T; Narita, N; Tanaka, H; Tsukaguchi, N; Yagi, H; Yoneda, K, 2001)
"We investigated FOY therapy for the treatment of disseminated intravascular coagulation (DIC) associated with sepsis in 15 patients (group F), and compared it with heparin therapy in 8 patients (group H)."5.27Gabexate mesilate (FOY) therapy of disseminated intravascular coagulation due to sepsis. ( Hirata, T; Kambayashi, J; Nishijima, MK; Shimada, Y; Taenaka, N; Takezawa, J; Yoshiya, I, 1983)
"Experimental disseminated intravascular coagulation (DIC) can be induced by 4 h sustained infusion of endotoxin at a dose of 100 mg/kg in rats."5.27Protective effect of gabexate mesilate against experimental disseminated intravascular coagulation in rats. ( Furukawa, Y; Kondo, M; Murakami, M; Takemura, S; Yoshikawa, T, 1983)
"Gabexate mesilate was more likely to attenuate neutrophil-mediated oxidative stress on microvasculature in endotoxin-induced DIC than heparin sodium."5.27Microcirculatory disturbances in endotoxin-induced disseminated intravascular coagulation. The effects of heparin and gabexate mesilate on locomotive and metabolic changes of neutrophils. ( Miura, S; Oda, M; Oshio, C; Suematsu, M; Suzuki, M; Tsuchiya, M, 1988)
"We hypothesized that antithrombin is more effective for disseminated intravascular coagulation (DIC) than is gabexate mesilate, which is a protease inhibitor, suggested from the previous studies."5.16Effects of antithrombin and gabexate mesilate on disseminated intravascular coagulation: a preliminary study. ( Kohno, Y; Koishi, K; Nishiyama, T, 2012)
"Gabexate mesilate (GM) is a promising anticoagulation treatment for disseminated intravascular coagulation (DIC)."5.11Efficacy of gabexate mesilate on disseminated intravascular coagulation as a complication of infection developing after abdominal surgery. ( Chen, HM; Chen, JC; Chen, MF; Chiu, DF; Hsu, JT; Huang, CJ; Hwang, TL; Jan, YY, 2004)
"To investigate the effect of a protease inhibitor, gabexate mesylate, on patients with pre- or mild disseminated intravascular coagulation (DIC) in comparison with a control group receiving no anticoagulation therapy."5.09Is protease inhibitor a choice for the treatment of pre- or mild disseminated intravascular coagulation? ( Hanaoka, K; Matsukawa, T; Nishiyama, T, 2000)
"The effects of gabexate mesilate on disseminated intravascular coagulation (DIC) accompanying neoplastic diseases or severe infections in ten patients were investigated and compared with those of heparin therapy in ten other patients with DIC."5.06Gabexate as a therapy for disseminated intravascular coagulation. ( Adachi, M; Soejima, R; Umeki, S; Watanabe, M; Yaji, S, 1988)
"We evaluated clinical outcomes of disseminated intravascular coagulation (DIC) in patients with hematological malignancies treated with synthetic protease inhibitors (SPIs) and compared the effects of gabexate mesilate (FOY) and nafamostat mesilate (FUT)."3.91Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies. ( Ashizawa, M; Fujiwara, SI; Hatano, K; Ikeda, T; Ito, S; Kanda, Y; Kawaguchi, SI; Kawasaki, Y; Mashima, K; Minakata, D; Morita, K; Muroi, K; Nagayama, T; Nakano, H; Ochi, SI; Oh, I; Ohmine, K; Ohmori, T; Sato, K; Sugimoto, M; Toda, Y; Umino, K; Yamamoto, C; Yamasaki, R, 2019)
"Efficacy of recombinant human soluble thrombomodulin (rhTM), which is frequently used to treat patients with disseminated intravascular coagulation (DIC), was compared with that of gabexate mesilate (GM), which was previously used routinely in the treatment of DIC patients in Japan."3.83The efficacy of the administration of recombinant human soluble thrombomodulin in patients with DIC. ( Aota, T; Imai, H; Isaji, S; Katayama, N; Matsumoto, T; Ohishi, K; Suzuki, K; Usui, M; Wada, H; Yamashita, Y, 2016)
" We retrospectively evaluated and compared the efficacies of rhTM and gabexate mesilate (GM) in patients diagnosed with sepsis-induced DIC."3.80A retrospective comparative study of recombinant human thrombomodulin and gabexate mesilate in sepsis-induced disseminated intravascular coagulation patients. ( Imamura, Y; Izumikawa, K; Kohno, S; Matsuo, N; Miyazaki, T; Nakamura, S; Sawai, T; Suyama, N; Takazono, T; Yanagihara, K; Yoshioka, S, 2014)
"25 mg/kg/hr for 4 hr) was shown to induce disseminated intravascular coagulation (DIC) in rats, which resulted in hypofibrinogenemia, prolongation of prothrombin (PT) and partial thromboplastin time (PTT), thrombocytopenia, and elevated levels of fibrinogen/fibrin degradation products (FDP)."3.68Effect of a selective PAF antagonist SM-10661 ((+/-)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one HCl) on experimental disseminated intravascular coagulation (DIC). ( Imanishi, N; Komuro, Y; Morooka, S, 1991)
"Sequential therapy consisting of methotrexate (MTX) and 5-FU was performed together with the administration of heparin and FOY in 10 cases of gastric cancer with disseminated intravascular coagulation (DIC) causing systemic bone metastasis."3.68[Sequential MTX and 5-FU therapy of gastric cancer with systemic bone metastasis and disseminated intravascular coagulation]. ( Ibuka, T; Imai, K; Ishiwata, J; Kobayashi, T; Monma, K; Ohno, T; Onozawa, Y; Sakaki, N; Sasaki, T; Tabata, I, 1992)
" MD-805 was also administered to ten patients with disseminated intravascular coagulation (DIC), eight of whom had not responded to either heparin or gabexate mesilate (FOY), and eight of whom had circulating antithrombin III levels below 20 mg/dl."3.67Anticoagulation with a synthetic thrombin inhibitor after cardiovascular surgery and for treatment of disseminated intravascular coagulation. ( Fujita, T; Kumon, K; Naito, Y; Nakajima, N; Tanaka, K, 1984)
"One hundred and ninety-one patients with disseminated intravascular coagulation syndrome (DIC) or its prodromal stage (preDIC) were treated with only gabaxate mesilate (FOY) (group G) or a combination of gabaxate and unfractionated heparin (group GH), and the efficacy of gabaxate was evaluated in a multicenter study."2.67Treatment of disseminated intravascular coagulation and its prodromal stage with gabaxate mesilate (FOY): a multi-center trial. ( Chiba, S; Hara, K; Ichimaru, M; Itoga, T; Kotsuru, M; Miyake, M; Niho, Y; Okamura, T; Saito, H; Takatsuki, K, 1993)
"Whereas in DIC associated with trauma, since balance between coagulation and fibrinolysis collapses drastically in a short period, both anticoagulantion therapy and antifibrinolytic therapy can be utilized depending on clinical conditions."2.53[Anti DIC therapy]. ( Sakamoto, Y; Yahata, M, 2016)
"A case of disseminated intravascular coagulation (DIC) in a patient with systemic lupus erythematosus (SLE) with acute liver dysfunction is described."2.38Disseminated intravascular coagulation in lupus erythematosus with acute liver damage. ( Kaneda, S; Sano, M; Shimamoto, Y; Tsunada, S; Yamaguchi, M; Yamamoto, K, 1992)
"Thyroid storm is a rare disorder with a sudden onset, rapid progression and high mortality."1.38Thyroid storm with multiple organ failure, disseminated intravascular coagulation, and stroke with a normal serum FT3 level. ( Akiyama, H; Handa, M; Harada, Y; Ryuzaki, M; Urao, Y; Yoshimoto, T, 2012)
"A 64-year-old man was diagnosed with acute myeloid leukemia (AML) complicated by disseminated intravascular coagulation."1.35Leukemia cutis originating in the extravasation site of i.v. gabexate mesilate infusion. ( Aota, Y; Iguchi, T; Kurashige, Y; Miyakura, T; Nagai, A; Tsuboi, R; Yamamoto, T, 2008)
"The case was complicated with disseminated intravascular coagulation."1.32[A case of severe Chlamydia pneumoniae pneumonia requiring mechanical ventilation and complicated with disseminated intravascular coagulation]. ( Arimura, Y; Ashitani, J; Kato, S; Sano, A; Yanagi, S, 2003)
"He was diagnosed as having chronic disseminated intravascular coagulation (DIC) complicated by a thoracoabdominal aortic aneurysm, and was treated with heparin sodium and a protease inhibitor."1.31[Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm]. ( Amano, I; Morii, T; Narita, N; Tanaka, H; Tsukaguchi, N; Yagi, H; Yoneda, K, 2001)
"We describe a case of thoracic aortic aneurysm complicated by chronic disseminated intravascular coagulation (DIC)."1.31[Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin]. ( Fukuda, N; Nakamori, Y; Oeda, E; Sato, Y; Shimohakamada, Y; Shinohara, K; Takahashi, T; Tominaga, T, 2002)
"Pyogenic osteomyelitis is often accompanied by diabetes, but the disease in the clavicula has rarely been reported."1.30Pyogenic clavicular osteomyelitis associated with disseminated intravascular coagulation and acute renal failure in a patient with non-insulin-dependent diabetes mellitus. ( Kasamatsu, Y; Kondo, M; Nagata, H; Nakamura, Y; Yokoo, S; Yoshida, T; Yoshioka, K, 1997)
"The status epilepticus was also attenuated by the use of thiamylal sodium."1.30[A successfully treated parkinsonian patient with neuroleptic malignant syndrome complicated by status epilepticus and disseminated intravascular coagulation]. ( Miyoshi, T; Motomura, S; Osoegawa, M; Tamura, K; Yamanaka, H, 1999)
"He was diagnosed as metastatic bone cancer with disseminated intravascular coagulation (DIC)."1.28Disseminated carcinomatosis of bone marrow from submucosal carcinoma in adenoma of the rectum. ( Andachi, H; Shimizu, H; Yokoo, S; Yoshioka, K, 1992)
"The occurrence of disseminated intravascular coagulation (DIC) is not rare in neurosurgical patients."1.28[Diagnosis and treatment of disseminated intravascular coagulation associated with neurosurgical diseases; a proposal of a new scoring system for DIC]. ( Fujii, Y; Kameyama, S; Koike, T; Takahashi, H; Tanaka, R, 1992)
"To investigate disseminated intravascular coagulation (DIC) after valve replacement, we studied DIC score in 80 patients with combined cardiac valvular disease."1.28[Disseminated intravascular coagulation (DIC) after artificial valve replacement: especially tricuspid regurgitation]. ( Abe, T; Hagiwara, K; Igari, T; Iwaya, F; Midorikawa, H; Sato, Y; Satokawa, H; Takase, S; Tanji, M; Watanabe, M, 1990)
"Experimental disseminated intravascular coagulation (DIC) can be induced by 4 h sustained infusion of endotoxin at a dose of 100 mg/kg in rats."1.27Protective effect of gabexate mesilate against experimental disseminated intravascular coagulation in rats. ( Furukawa, Y; Kondo, M; Murakami, M; Takemura, S; Yoshikawa, T, 1983)
"We investigated FOY therapy for the treatment of disseminated intravascular coagulation (DIC) associated with sepsis in 15 patients (group F), and compared it with heparin therapy in 8 patients (group H)."1.27Gabexate mesilate (FOY) therapy of disseminated intravascular coagulation due to sepsis. ( Hirata, T; Kambayashi, J; Nishijima, MK; Shimada, Y; Taenaka, N; Takezawa, J; Yoshiya, I, 1983)
"Gabexate mesilate was more likely to attenuate neutrophil-mediated oxidative stress on microvasculature in endotoxin-induced DIC than heparin sodium."1.27Microcirculatory disturbances in endotoxin-induced disseminated intravascular coagulation. The effects of heparin and gabexate mesilate on locomotive and metabolic changes of neutrophils. ( Miura, S; Oda, M; Oshio, C; Suematsu, M; Suzuki, M; Tsuchiya, M, 1988)
"These changes included acute disseminated intravascular coagulation, severe elevations of liver enzymes, severe renal dysfunction, and hemolytic anemia."1.27A case of postpartum hemolytic uremic syndrome with severe elevations of liver enzymes. ( Fujii, S; Kanzaki, H; Kariya, M; Matsuura, S; Mori, T; Sagawa, N, 1985)
"Coagulation studies revealed disseminated intravascular coagulation and a diagnosis of amniotic fluid embolism was made."1.26Survival from DIC following amniotic fluid embolism. Successful treatment with a serine proteinase inhibitor; FOY. ( Kawai, M; Kosaki, G; Shimada, Y; Taenaka, N; Yoshiya, I, 1981)

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199030 (34.88)18.7374
1990's30 (34.88)18.2507
2000's12 (13.95)29.6817
2010's14 (16.28)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ookura, M1
Hosono, N1
Tasaki, T1
Oiwa, K1
Fujita, K1
Ito, K1
Lee, S1
Matsuda, Y1
Morita, M2
Tai, K1
Negoro, E1
Kishi, S1
Iwasaki, H1
Ueda, T1
Yamauchi, T1
Minakata, D1
Fujiwara, SI1
Ikeda, T2
Kawaguchi, SI1
Toda, Y1
Ito, S1
Ochi, SI1
Nagayama, T1
Mashima, K1
Umino, K1
Nakano, H1
Yamasaki, R1
Morita, K1
Kawasaki, Y1
Sugimoto, M1
Yamamoto, C1
Ashizawa, M1
Hatano, K1
Sato, K1
Oh, I1
Ohmine, K1
Muroi, K1
Ohmori, T1
Kanda, Y1
Hashimoto, D1
Okawa, T1
Maruyama, R1
Matsumura, F1
Shibata, Y1
Kohrogi, H1
Gando, S2
Saitoh, D1
Ishikura, H1
Ueyama, M1
Otomo, Y1
Oda, S1
Kushimoto, S1
Tanjoh, K1
Mayumi, T1
Iba, T1
Eguchi, Y1
Okamoto, K2
Ogura, H1
Koseki, K1
Sakamoto, Y2
Takayama, Y1
Shirai, K1
Takasu, O1
Inoue, Y1
Mashiko, K1
Tsubota, T1
Endo, S1
Wada, H5
Matsumoto, T2
Yamashita, Y2
Takazono, T1
Nakamura, S1
Imamura, Y1
Yoshioka, S1
Miyazaki, T1
Izumikawa, K1
Sawai, T1
Matsuo, N1
Yanagihara, K1
Suyama, N1
Kohno, S1
Akahoshi, T1
Sugimori, H1
Kaku, N1
Tokuda, K1
Nagata, T1
Noda, E1
Hashizume, M1
Maehara, Y1
Aota, T1
Ohishi, K1
Suzuki, K2
Imai, H1
Usui, M1
Isaji, S1
Katayama, N1
Yahata, M1
Sakata, Y1
Koyama, T2
Kumura, T1
Aoyama, Y1
Ichihara, H1
Koh, S1
Mugitani, A1
Hayakawa, H1
Yukioka, K1
Kinoshita, D1
Nakagawa, M1
Yamazaki, N1
Takahashi, H3
Nishiyama, T2
Kohno, Y1
Koishi, K1
Harada, Y1
Akiyama, H1
Yoshimoto, T1
Urao, Y1
Ryuzaki, M1
Handa, M1
Sakakura, M1
Saito, T1
Tsuchiya, M2
Shikata, C1
Yamaguchi, H1
Miyata, S1
Matsuo, S1
Ishizawa, S1
Yoshimura, K1
Yanagi, S1
Ashitani, J1
Arimura, Y1
Sano, A1
Kato, S1
Hsu, JT1
Chen, HM1
Chiu, DF1
Chen, JC1
Huang, CJ1
Hwang, TL1
Jan, YY1
Chen, MF1
Miyakura, T1
Yamamoto, T1
Kurashige, Y1
Nagai, A1
Iguchi, T1
Aota, Y1
Tsuboi, R1
Kosaki, G3
Kambayashi, J3
Imaoka, S1
Taenaka, N2
Shimada, Y2
Hirata, T1
Nishijima, MK1
Takezawa, J1
Yoshiya, I2
Yoshikawa, T3
Furukawa, Y3
Murakami, M2
Takemura, S2
Kondo, M4
Maki, M3
Soga, K1
Gotoh, K1
Kojima, M1
Shimamura, K1
Mori, N1
Oka, K1
Nakazawa, M1
Tamakuma, S1
Ogawa, Y1
Saito, A1
Tsukawaki, Y1
Nioka, S1
Yoda, K1
Miyazaki, M1
Kusaka, Y1
Ban, S1
Chihara, K1
Akiyama, F1
Shinozaki, T1
Shimamoto, M1
Takahashi, K1
Imura, H1
Yamazaki, F1
Kawarazaki, S1
Kumon, K1
Tanaka, K1
Nakajima, N1
Naito, Y1
Fujita, T1
Kawai, M1
Iwasa, K1
Izumi, R1
Shimizu, K1
Li, T1
Masutani, H1
Lyobe, T1
Fukushima, W1
Sakamoto, K1
Inoue, T1
Muraoka, K1
Okamura, T2
Niho, Y2
Itoga, T1
Chiba, S1
Miyake, M1
Kotsuru, M1
Saito, H3
Ichimaru, M1
Hara, K1
Takatsuki, K1
Iwabuchi, S1
Takatori, M1
Okabe, K1
Aramoto, H1
Shigematsu, H1
Muto, T1
Yawata, Y1
Okuda, T1
Yumoto, Y1
Ukai, K1
Fuji, A1
Nishiwaki, J1
Yamada, T1
Hotta, N1
Kobayashi, Y1
Kondo, C1
Miyajima, K1
Takada, T1
Kinoshita, Y1
Hanai, S1
Yuasa, T1
Taniguchi, Y1
Yamada, E1
Inachi, S1
Shimizu, M1
Yoshioka, K2
Nagata, H1
Nakamura, Y2
Kasamatsu, Y1
Yokoo, S2
Yoshida, T1
Terasako, K1
Shinohara, T1
Hidaka, T1
Matsuki, Y1
Ohsuzu, F1
Osoegawa, M1
Motomura, S1
Yamanaka, H1
Tamura, K1
Miyoshi, T1
Matsukawa, T1
Hanaoka, K1
Ita, M1
Okafuji, M1
Maruoka, Y1
Shinozaki, F1
Yoneda, K1
Amano, I1
Tanaka, H2
Yagi, H1
Tsukaguchi, N1
Morii, T1
Narita, N1
Yokota, T1
Yamada, Y1
Takahashi, M1
Kunii, Y1
Iwamoto, K1
Kagami, M1
Kikuchi, S1
Yamauchi, H1
Yoshikawa, K1
Fukuda, N1
Shimohakamada, Y1
Nakamori, Y1
Tominaga, T1
Shinohara, K1
Takahashi, T1
Oeda, E1
Sato, Y2
Kashima, K1
Kataoka, K1
Umehara, K1
Shimamoto, Y1
Sano, M1
Kaneda, S1
Tsunada, S1
Yamamoto, K1
Yamaguchi, M1
Kobayashi, T1
Sasaki, T1
Ibuka, T1
Imai, K1
Monma, K1
Sakaki, N1
Tabata, I1
Ishiwata, J1
Onozawa, Y1
Ohno, T1
Shimizu, H1
Andachi, H1
Murakawa, M1
Shibuya, T1
Harada, M1
Otsuka, T1
Kameyama, S1
Fujii, Y1
Koike, T1
Tanaka, R1
Kazama, M1
Kobayashi, K1
Tahara, C1
Miyajima, Y1
Endo, Y1
Nakatani, T1
Tajimi, K1
Yoshida, K2
Toki, F1
Takeuchi, T1
Motoki, R1
Inoue, H1
Imanishi, N1
Komuro, Y1
Morooka, S1
Kobayashi, N1
Yasunaga, M1
Mori, K2
Yamashita, S1
Okita, K1
Takeda, S2
Ohsato, K1
Satokawa, H1
Iwaya, F1
Igari, T1
Abe, T1
Hagiwara, K1
Tanji, M1
Watanabe, M2
Midorikawa, H1
Takase, S1
Wakui, K1
Takemae, T1
Kobayashi, S1
Tsuzuki, T1
Toyama, K1
Nakayasu, K1
Iida, S1
Ueda, M1
Toizumi, A1
Murata, M1
Hayakawa, M1
Goto, K1
Isobe, K1
Matuura, T1
Hirano, H1
Higuchi, M1
Toyoda, O1
Nojiri, K1
Nakajima, H1
Takemoto, Y1
Tanaka, S1
Tanabe, J1
Kohama, A1
Shibata, S1
Terada, H1
Suzuki, H3
Deguchi, A2
Mori, Y2
Okubo, I1
Tsuda, M2
Nagano, T1
Deguchi, K2
Shirakawa, S2
Yajima, Y1
Otsuki, M1
Goto, Y1
Terao, T1
Ikenoue, T1
Takemura, T1
Sekiba, K1
Shirakawa, K1
Soma, H1
Mukaiyama, H1
Shionoya, S1
Ikezawa, T1
Kamiya, T1
Hamaguchi, M1
Kume, M1
Takechi, K1
Kasamatsu, T1
Kinoshita, K1
Mizuno, M1
Sakamoto, S1
Umeki, S1
Adachi, M1
Yaji, S1
Soejima, R1
Oukubo, I1
Tanaka, I1
Minami, N1
Taniguchi, N1
Kitani, T1
Kawagoe, H1
Horiuchi, A1
Masaoka, T1
Yasunaga, K1
Okamoto, Y1
Ohkubo, A1
Yonezawa, T1
Nagai, K1
Suzuki, M1
Suematsu, M1
Miura, S1
Oshio, C1
Oda, M1
Tedo, I1
Sagawa, N1
Kariya, M1
Kanzaki, H1
Fujii, S1
Matsuura, S1
Mori, T1
Ishikawa, H1
Ishikawa, S1
Rinsho, K1
Yazaki, T1
Kanoh, S1
Koiso, K1
Uchida, K1
Iizumi, T1
Takeshima, H1
Umeyama, T1
Kato, H1
Sugino, S1
Yamada, K1
Matsuda, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
RAndomized Clinical Trial in COvid19 Patients to Assess the Efficacy of the Transmembrane Protease Serine 2 (TMPRSS2) Inhibitor NAfamostat (RACONA Study)[NCT04352400]Phase 2/Phase 3256 participants (Anticipated)Interventional2021-06-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

17 reviews available for gabexate and Disseminated Intravascular Coagulation

ArticleYear
Anticoagulant Therapy for Disseminated Intravascular Coagulation After Gastrointestinal Surgery.
    Anticancer research, 2019, Volume: 39, Issue:1

    Topics: Anticoagulants; Digestive System Surgical Procedures; Disseminated Intravascular Coagulation; Gabexa

2019
[Recent therapeutic strategy for disseminated intravascular coagulation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:1

    Topics: Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzamidines; Disseminated Intravascular Coa

2014
[Anti DIC therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:2

    Topics: Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzamidines; Disseminated Intravascular Coa

2016
[Treatment of DIC associated with myelogenous leukemia].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:10

    Topics: Anticoagulants; Disseminated Intravascular Coagulation; Gabexate; Heparin; Humans; Leukemia, Myeloid

2009
[Treatment of disseminated intravascular coagulation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2010, Volume: 51, Issue:1

    Topics: Anticoagulants; Antithrombins; Benzamidines; Chondroitin Sulfates; Dalteparin; Dermatan Sulfate; Dis

2010
[Synthetic protease inhibitors for the treatment of DIC].
    Rinsho byori. The Japanese journal of clinical pathology, 2011, Volume: Suppl 147

    Topics: Anticoagulants; Arginine; Benzamidines; Disseminated Intravascular Coagulation; Gabexate; Guanidines

2011
[Prevention of hemorrhage occurring in patients with leukemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2003, Jun-10, Volume: 92, Issue:6

    Topics: Anticoagulants; Disseminated Intravascular Coagulation; Gabexate; Heparin; Humans; Leukemia; Platele

2003
[Drug-induced disseminated intravascular coagulation (DIC)].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Animals; Anticoagulants; Antineoplastic Agents; Blood Coagulation Factors; Disseminated Intravascula

2007
[Principles of the therapy for disseminated intravascular coagulation: current status and new trends].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:1

    Topics: Antifibrinolytic Agents; Antithrombin III; Blood Component Transfusion; Disseminated Intravascular C

1993
[Synthetic protease inhibitors in the treatment of disseminated intravascular coagulation].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:1

    Topics: Benzamidines; Disseminated Intravascular Coagulation; Gabexate; Glycoproteins; Guanidines; Half-Life

1993
[Emergency therapy of disseminated intravascular coagulation].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1995, Nov-10, Volume: 84, Issue:11

    Topics: Anticoagulants; Blood Coagulation; Disseminated Intravascular Coagulation; Emergencies; Gabexate; He

1995
Severe cutaneous and venous damage after DIC therapy.
    The Journal of dermatology, 1997, Volume: 24, Issue:7

    Topics: Aged; Anticoagulants; Disseminated Intravascular Coagulation; Female; Gabexate; Humans; Necrosis; Sa

1997
Disseminated intravascular coagulation in lupus erythematosus with acute liver damage.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:12

    Topics: Adult; Antithrombin III; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Gabexate

1992
[Thrombosis in various diseases: disseminated intravascular coagulation and thrombosis].
    Nihon rinsho. Japanese journal of clinical medicine, 1986, Volume: 44, Issue:5

    Topics: Blood Coagulation; Disseminated Intravascular Coagulation; Fibrinolysis; Gabexate; Guanidines; Hepar

1986
[Complement and disseminated intravascular coagulation].
    Rinsho byori. The Japanese journal of clinical pathology, 1985, Volume: Spec No 63

    Topics: Animals; Antigen-Antibody Complex; Complement Inactivator Proteins; Complement System Proteins; Dise

1985
[Newborn infants and disseminated intravascular coagulation].
    Rinsho byori. The Japanese journal of clinical pathology, 1985, Volume: Spec No 63

    Topics: Bacterial Infections; Blood Coagulation Tests; Diagnosis, Differential; Disseminated Intravascular C

1985
[Therapy of disseminated intravascular coagulation].
    Rinsho byori. The Japanese journal of clinical pathology, 1985, Volume: Spec No 63

    Topics: Antifibrinolytic Agents; Antithrombin III; Blood Coagulation Tests; Blood Transfusion; Disseminated

1985

Trials

7 trials available for gabexate and Disseminated Intravascular Coagulation

ArticleYear
A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis.
    Critical care (London, England), 2013, Dec-16, Volume: 17, Issue:6

    Topics: Aged; Antithrombins; Blood Coagulation; Disseminated Intravascular Coagulation; Drug Administration

2013
Effects of antithrombin and gabexate mesilate on disseminated intravascular coagulation: a preliminary study.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antithrombin III; Antithrombins; C-Reactive Protein;

2012
Efficacy of gabexate mesilate on disseminated intravascular coagulation as a complication of infection developing after abdominal surgery.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2004, Volume: 103, Issue:9

    Topics: Abdomen; Anticoagulants; APACHE; Disseminated Intravascular Coagulation; Female; Gabexate; Humans; I

2004
Treatment of disseminated intravascular coagulation and its prodromal stage with gabaxate mesilate (FOY): a multi-center trial.
    Acta haematologica, 1993, Volume: 90, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Disseminated Intravascular Coagulation; Drug Therapy, Co

1993
Is protease inhibitor a choice for the treatment of pre- or mild disseminated intravascular coagulation?
    Critical care medicine, 2000, Volume: 28, Issue:5

    Topics: Adult; Aged; Blood Coagulation Tests; Critical Care; Disseminated Intravascular Coagulation; Female;

2000
Clinical evaluation of antithrombin III concentrate (BI 6.013) for disseminated intravascular coagulation in obstetrics. Well-controlled multicenter trial.
    Gynecologic and obstetric investigation, 1987, Volume: 23, Issue:4

    Topics: Adult; Antithrombin III; Blood Chemical Analysis; Clinical Trials as Topic; Disseminated Intravascul

1987
Gabexate as a therapy for disseminated intravascular coagulation.
    Archives of internal medicine, 1988, Volume: 148, Issue:6

    Topics: Anticoagulants; Clinical Trials as Topic; Disseminated Intravascular Coagulation; Gabexate; Guanidin

1988

Other Studies

62 other studies available for gabexate and Disseminated Intravascular Coagulation

ArticleYear
Successful treatment of disseminated intravascular coagulation by recombinant human soluble thrombomodulin in patients with acute myeloid leukemia.
    Medicine, 2018, Volume: 97, Issue:44

    Topics: Adolescent; Aged; Aged, 80 and over; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinog

2018
Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies.
    International journal of hematology, 2019, Volume: 109, Issue:2

    Topics: Adult; Anticoagulants; Benzamidines; Disseminated Intravascular Coagulation; Female; Gabexate; Guani

2019
A retrospective comparative study of recombinant human thrombomodulin and gabexate mesilate in sepsis-induced disseminated intravascular coagulation patients.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2014, Volume: 20, Issue:8

    Topics: Aged; Aged, 80 and over; Analysis of Variance; C-Reactive Protein; Disseminated Intravascular Coagul

2014
Comparison of recombinant human thrombomodulin and gabexate mesylate for treatment of disseminated intravascular coagulation (DIC) with sepsis following emergent gastrointestinal surgery: a retrospective study.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2015, Volume: 41, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Critical Care; Disseminated Intravascular Coagulatio

2015
The efficacy of the administration of recombinant human soluble thrombomodulin in patients with DIC.
    International journal of hematology, 2016, Volume: 103, Issue:2

    Topics: Adult; Aged; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinogen Degradation Products;

2016
[Successful treatment with the combination of recombinant human soluble thrombomodulin and gabexate mesilate in three patients with obstetric disseminated intravascular coagulation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2011, Volume: 52, Issue:2

    Topics: Abruptio Placentae; Adult; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Female

2011
Thyroid storm with multiple organ failure, disseminated intravascular coagulation, and stroke with a normal serum FT3 level.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:17

    Topics: Anti-Inflammatory Agents; Anticoagulants; Antithyroid Agents; Brain Edema; Decompression, Surgical;

2012
Microscopic polyangiitis associated with marked systemic bleeding tendency caused by disseminated intravascular coagulation.
    Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:9

    Topics: Antibodies, Antineutrophil Cytoplasmic; Anticoagulants; Disseminated Intravascular Coagulation; Fata

2003
[A case of severe Chlamydia pneumoniae pneumonia requiring mechanical ventilation and complicated with disseminated intravascular coagulation].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2003, Volume: 41, Issue:11

    Topics: Acute Disease; Chlamydophila Infections; Chlamydophila pneumoniae; Disseminated Intravascular Coagul

2003
Leukemia cutis originating in the extravasation site of i.v. gabexate mesilate infusion.
    The Journal of dermatology, 2008, Volume: 35, Issue:1

    Topics: Anticoagulants; Disseminated Intravascular Coagulation; Extravasation of Diagnostic and Therapeutic

2008
Application of a synthetic serine protease inhibitor in the treatment of DIC.
    Bibliotheca haematologica, 1983, Issue:49

    Topics: Animals; Chemical Phenomena; Chemistry; Disease Models, Animal; Disseminated Intravascular Coagulati

1983
Gabexate mesilate (FOY) therapy of disseminated intravascular coagulation due to sepsis.
    Critical care medicine, 1983, Volume: 11, Issue:9

    Topics: Adult; Aged; Anticoagulants; Bacterial Infections; Disseminated Intravascular Coagulation; Female; G

1983
Protective effect of gabexate mesilate against experimental disseminated intravascular coagulation in rats.
    Haemostasis, 1983, Volume: 13, Issue:4

    Topics: Animals; Blood Coagulation Tests; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinogen

1983
The kinin-forming enzyme system in pregnancy and obstetrical DIC.
    Bibliotheca haematologica, 1983, Issue:49

    Topics: Adult; Animals; Disseminated Intravascular Coagulation; Female; Gabexate; Guanidines; Humans; Kallik

1983
A histological study on microthrombi in autopsy cases of DIC.
    Bibliotheca haematologica, 1983, Issue:49

    Topics: Disseminated Intravascular Coagulation; Female; Gabexate; Guanidines; Heparin; Humans; Kidney Glomer

1983
[Severe surgical infection and DIC].
    Nihon Geka Gakkai zasshi, 1983, Volume: 84, Issue:9

    Topics: Adult; Aged; Animals; Bacterial Infections; Blood Coagulation Factors; Disseminated Intravascular Co

1983
[Fungal sepsis and DIC in surgical patients].
    Nihon Geka Gakkai zasshi, 1983, Volume: 84, Issue:9

    Topics: Adult; Aged; Amphotericin B; Disseminated Intravascular Coagulation; Female; Flucytosine; Gabexate;

1983
[Pre- and post-operative management of Kasabach-Merritt syndrome].
    Masui. The Japanese journal of anesthesiology, 1984, Volume: 33, Issue:4

    Topics: Blood Coagulation; Disseminated Intravascular Coagulation; Fibrous Dysplasia of Bone; Fibrous Dyspla

1984
[Disseminated intravascular coagulation (DIC) following open heart surgery and great vessel surgery. The result of early administration of gabexate mesilate (FOY)].
    Kyobu geka. The Japanese journal of thoracic surgery, 1984, Volume: 37, Issue:8

    Topics: Adolescent; Adult; Aged; Blood Transfusion; Cardiac Surgical Procedures; Coronary Disease; Dissemina

1984
Anticoagulation with a synthetic thrombin inhibitor after cardiovascular surgery and for treatment of disseminated intravascular coagulation.
    Critical care medicine, 1984, Volume: 12, Issue:12

    Topics: Adult; Aged; Antithrombin III; Arginine; Cardiovascular Diseases; Disseminated Intravascular Coagula

1984
Survival from DIC following amniotic fluid embolism. Successful treatment with a serine proteinase inhibitor; FOY.
    Anaesthesia, 1981, Volume: 36, Issue:4

    Topics: Adult; Blood Transfusion; Disseminated Intravascular Coagulation; Embolism, Amniotic Fluid; Female;

1981
[Protection of endotoxin-induced disseminated intravascular coagulation in rats by gabexate mesilate].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1982, Volume: 45, Issue:3

    Topics: Animals; Disseminated Intravascular Coagulation; Endotoxins; Female; Gabexate; Guanidines; Polysacch

1982
Effect of cryopreservation on the immunogenicity of pancreatic islets in xenotransplantation.
    Transplantation proceedings, 1994, Volume: 26, Issue:4

    Topics: Animals; Blood Glucose; Cell Separation; Collagenases; Cryopreservation; Dimethyl Sulfoxide; Dissemi

1994
[Adequate parameters for the diagnosis of disseminated intravascular coagulation (DIC) in patients with liver diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:1

    Topics: Adult; Antithrombin III; Biomarkers; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinog

1993
[Reactive hemophagocytic syndrome responded to combination chemotherapy with steroid pulse therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disseminated Intravascular C

1995
Giant hepatic angiomyolipoma associated with disseminated intravascular coagulation.
    Internal medicine (Tokyo, Japan), 1997, Volume: 36, Issue:3

    Topics: Aged; Angiomyolipoma; Anticoagulants; Disseminated Intravascular Coagulation; Female; Fibrinolysis;

1997
Pyogenic clavicular osteomyelitis associated with disseminated intravascular coagulation and acute renal failure in a patient with non-insulin-dependent diabetes mellitus.
    Internal medicine (Tokyo, Japan), 1997, Volume: 36, Issue:11

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Anticoagulants; Clavicle; Diabetes Mellitus, Type 2; Dis

1997
Disseminated intravascular coagulation in a patient undergoing removal of humeral head for pain relief.
    Anaesthesia and intensive care, 1999, Volume: 27, Issue:3

    Topics: Aged; Anticoagulants; Blood Transfusion; Disseminated Intravascular Coagulation; Female; Gabexate; G

1999
Calcinosis cutis and intestinal pseudoobstruction in a patient with adult onset Still's disease associated with recurrent relapses of disordered coagulopathy.
    Internal medicine (Tokyo, Japan), 1999, Volume: 38, Issue:6

    Topics: Anticoagulants; Calcinosis; Diagnosis, Differential; Disseminated Intravascular Coagulation; Drug Th

1999
[A successfully treated parkinsonian patient with neuroleptic malignant syndrome complicated by status epilepticus and disseminated intravascular coagulation].
    Rinsho shinkeigaku = Clinical neurology, 1999, Volume: 39, Issue:6

    Topics: Anticoagulants; Antiparkinson Agents; Bromocriptine; Dantrolene; Disseminated Intravascular Coagulat

1999
An unusual postextraction hemorrhage associated with Klippel-Trenaunay-Weber syndrome.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2001, Volume: 59, Issue:2

    Topics: Adult; Anticoagulants; Dental Care for Chronically Ill; Disseminated Intravascular Coagulation; Fema

2001
[Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2001, Volume: 42, Issue:1

    Topics: Administration, Oral; Aged; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Chronic Disease;

2001
Successful treatment of DIC with a serine proteinase inhibitor.
    The American journal of emergency medicine, 2001, Volume: 19, Issue:4

    Topics: Aged; Disseminated Intravascular Coagulation; Gabexate; Humans; Male; Serine Proteinase Inhibitors

2001
[Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2002, Volume: 43, Issue:3

    Topics: Administration, Oral; Aged; Anticoagulants; Aortic Aneurysm, Thoracic; Aspirin; Chronic Disease; Dis

2002
[Treatment of acute pancreatitis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Dec-10, Volume: 81, Issue:12

    Topics: Acute Disease; Benzamidines; Disseminated Intravascular Coagulation; Drainage; Gabexate; Glycoprotei

1992
[Sequential MTX and 5-FU therapy of gastric cancer with systemic bone metastasis and disseminated intravascular coagulation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol

1992
Disseminated carcinomatosis of bone marrow from submucosal carcinoma in adenoma of the rectum.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:8

    Topics: Adenoma; Anemia, Hemolytic; Antithrombin III; Bone Neoplasms; Carcinoma; Disseminated Intravascular

1992
Use of a synthetic protease inhibitor for the treatment of L-asparaginase-induced acute pancreatitis complicated by disseminated intravascular coagulation.
    Annals of hematology, 1992, Volume: 64, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Benz

1992
[Diagnosis and treatment of disseminated intravascular coagulation associated with neurosurgical diseases; a proposal of a new scoring system for DIC].
    No shinkei geka. Neurological surgery, 1992, Volume: 20, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Diseases; Brain Injuries; Cerebrovascular Disorder

1992
[Improving effect of the synthetic protease inhibitor E-3123 on experimental DIC in dogs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:1

    Topics: Animals; Blood Coagulation Tests; Disease Models, Animal; Disseminated Intravascular Coagulation; Do

1992
[Antienzyme preparations in the treatment of acute pancreatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:1

    Topics: Acute Disease; Adult; Aprotinin; Benzamidines; Cytidine Diphosphate Choline; Disseminated Intravascu

1990
[Protease inhibitors in shock].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Aprotinin; Disseminated Intravascular Coagulation; Gabexate; Glycoproteins; Humans; Infant, Newborn;

1991
Effect of a selective PAF antagonist SM-10661 ((+/-)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one HCl) on experimental disseminated intravascular coagulation (DIC).
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Administration, Oral; Animals; Disseminated Intravascular Coagulation; Endotoxins; Fibrin Fibrinogen

1991
[Physiopathology and therapy of disseminated intravascular coagulation].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Jun-10, Volume: 80, Issue:6

    Topics: Antithrombin III; Disseminated Intravascular Coagulation; Gabexate; Heparin; Humans

1991
[Clinical trial of protease inhibitor in the treatment of fulminant hepatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Animals; Antithrombin III; Disseminated Intravascular Coagulation; Gabexate; Hepatitis; Humans; Prot

1991
[Treatment of disseminated intravascular coagulation with proteinase inhibitor].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Antithrombin III; Benzamidines; Disseminated Intravascular Coagulation; Drug Therapy, Combination; F

1991
[Disseminated intravascular coagulation (DIC) after artificial valve replacement: especially tricuspid regurgitation].
    Kyobu geka. The Japanese journal of thoracic surgery, 1990, Volume: 43, Issue:4

    Topics: Adult; Aged; Anticoagulants; Disseminated Intravascular Coagulation; Female; Gabexate; Guanidines; H

1990
[Evaluation of FOY therapy for DIC or pre-DIC associated with neurosurgical disease].
    No shinkei geka. Neurological surgery, 1990, Volume: 18, Issue:7

    Topics: Anticoagulants; Disseminated Intravascular Coagulation; Drug Evaluation; Female; Fibrin Fibrinogen D

1990
Disseminated intravascular coagulation after hepatic resection.
    Surgery, 1990, Volume: 107, Issue:2

    Topics: Anticoagulants; Bile Ducts; Carcinoma, Hepatocellular; Disseminated Intravascular Coagulation; Fibri

1990
[Anticoagulant therapy in obstetrical disorders].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:6

    Topics: Antithrombin III; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Female; Fetal G

1990
[Studies of two cases of ruptured intracranial aneurysm with disseminated intravascular coagulation].
    No shinkei geka. Neurological surgery, 1989, Volume: 17, Issue:11

    Topics: Aged; Anticoagulants; Disseminated Intravascular Coagulation; Female; Gabexate; Guanidines; Humans;

1989
Studies on the effects of primary therapy for DIC following circulatory arrest.
    American journal of hematology, 1986, Volume: 21, Issue:4

    Topics: Animals; Anticoagulants; Benzamidines; Blood Coagulation Tests; Disseminated Intravascular Coagulati

1986
[Treatment of pre-disseminated intravascular coagulation state with gabexate mesilate (FOY)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1986, Volume: 27, Issue:12

    Topics: Anticoagulants; Disseminated Intravascular Coagulation; Gabexate; Guanidines; Humans

1986
A case of liver cirrhosis complicated with endotoxemia and disseminated intravascular coagulation: a case report.
    The Tohoku journal of experimental medicine, 1987, Volume: 151, Issue:3

    Topics: Disseminated Intravascular Coagulation; Endotoxins; Female; Gabexate; Guanidines; Humans; Liver Cirr

1987
Abdominal aortic aneurysm complicated with chronic disseminated intravascular coagulopathy: a case of surgical treatment.
    Journal of vascular surgery, 1987, Volume: 6, Issue:6

    Topics: Aged; Anticoagulants; Aorta, Abdominal; Aortic Aneurysm; Blood Vessel Prosthesis; Disseminated Intra

1987
The effect of a serine proteinase inhibitor on DIC in septic abortion.
    Asia-Oceania journal of obstetrics and gynaecology, 1987, Volume: 13, Issue:4

    Topics: Abortion, Septic; Adult; Anticoagulants; Disseminated Intravascular Coagulation; Female; Gabexate; G

1987
[Treatment of disseminated intravascular coagulation (DIC) or pre-DIC with gabexate mesilate (FOY)].
    Nihon Gan Chiryo Gakkai shi, 1988, Jan-20, Volume: 23, Issue:1

    Topics: Anticoagulants; Disseminated Intravascular Coagulation; Gabexate; Guanidines; Heparin; Humans; Leuke

1988
[Effects of FOY on DIC patients associated with hematological neoplastic disorders. Hanshin Cooperative Study Group of Hematological Disorders].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1987, Volume: 28, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Disseminated Intravascular Coagulation; Drug Evaluation; Fe

1987
Microcirculatory disturbances in endotoxin-induced disseminated intravascular coagulation. The effects of heparin and gabexate mesilate on locomotive and metabolic changes of neutrophils.
    Advances in experimental medicine and biology, 1988, Volume: 242

    Topics: Animals; Chemotaxis, Leukocyte; Disseminated Intravascular Coagulation; Endotoxins; Free Radicals; G

1988
[An analysis of disseminated intravascular coagulation by fibrinopeptides].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:12

    Topics: Adult; Aged; Blood Coagulation; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinogen De

1988
A case of postpartum hemolytic uremic syndrome with severe elevations of liver enzymes.
    Obstetrics and gynecology, 1985, Volume: 65, Issue:5

    Topics: Adult; Alkaline Phosphatase; Disseminated Intravascular Coagulation; Female; Furosemide; Gabexate; G

1985
[Clinical study on DIC in urological malignancies].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1985, Volume: 76, Issue:2

    Topics: Aged; Disseminated Intravascular Coagulation; Female; Gabexate; Guanidines; Heparin; Humans; Male; M

1985