gabexate has been researched along with Chronic Illness in 14 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An experimental model of chronic pancreatitis was induced by a retrograde injection of a viscous solution consisting of zein-oleic acid-linoleic acid (0." | 7.70 | Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct. ( Kashima, K; Kataoka, K; Sakagami, J; Sasaki, T; Yorizumi, H, 1998) |
| "This study examined the effects of GM on hepatic encephalopathy in rats with acute and chronic liver failure." | 5.36 | Lack of therapeutic effects of gabexate mesilate on the hepatic encephalopathy in rats with acute and chronic hepatic failure. ( Chan, CY; Chang, CC; Hsu, CY; Huang, HC; Huo, TI; Lee, FY; Lee, SD; Lin, HC; Teng, TH; Wang, SS, 2010) |
| "He was diagnosed as having chronic disseminated intravascular coagulation (DIC) complicated by a thoracoabdominal aortic aneurysm, and was treated with heparin sodium and a protease inhibitor." | 5.31 | [Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm]. ( Amano, I; Morii, T; Narita, N; Tanaka, H; Tsukaguchi, N; Yagi, H; Yoneda, K, 2001) |
| "We describe a case of thoracic aortic aneurysm complicated by chronic disseminated intravascular coagulation (DIC)." | 5.31 | [Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin]. ( Fukuda, N; Nakamori, Y; Oeda, E; Sato, Y; Shimohakamada, Y; Shinohara, K; Takahashi, T; Tominaga, T, 2002) |
| "An experimental model of chronic pancreatitis was induced by a retrograde injection of a viscous solution consisting of zein-oleic acid-linoleic acid (0." | 3.70 | Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct. ( Kashima, K; Kataoka, K; Sakagami, J; Sasaki, T; Yorizumi, H, 1998) |
| "The effect of oral administration of protease inhibitor (camostat) on pancreatic morphology and exocrine function (conscious rat model) was investigated using WBN/Kob rats with spontaneous chronic pancreatitis." | 3.69 | Effect of oral administration of protease inhibitor on pancreatic exocrine function in WBN/Kob rats with chronic pancreatitis. ( Atomi, Y; Kobori, O; Kuroda, A; Muto, T; Sugiyama, M; Wada, N, 1996) |
| "In about 1% acute pancreatitis or recurrency of chronic pancreatitis occurs." | 2.65 | [Effect of secretin and gabexate-mesilate (synthetic protease inhibitor) on serum amylase level after ERCP]. ( Rösch, W; Tympner, F, 1982) |
| "This study examined the effects of GM on hepatic encephalopathy in rats with acute and chronic liver failure." | 1.36 | Lack of therapeutic effects of gabexate mesilate on the hepatic encephalopathy in rats with acute and chronic hepatic failure. ( Chan, CY; Chang, CC; Hsu, CY; Huang, HC; Huo, TI; Lee, FY; Lee, SD; Lin, HC; Teng, TH; Wang, SS, 2010) |
| "He was diagnosed as having chronic disseminated intravascular coagulation (DIC) complicated by a thoracoabdominal aortic aneurysm, and was treated with heparin sodium and a protease inhibitor." | 1.31 | [Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm]. ( Amano, I; Morii, T; Narita, N; Tanaka, H; Tsukaguchi, N; Yagi, H; Yoneda, K, 2001) |
| "We describe a case of thoracic aortic aneurysm complicated by chronic disseminated intravascular coagulation (DIC)." | 1.31 | [Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin]. ( Fukuda, N; Nakamori, Y; Oeda, E; Sato, Y; Shimohakamada, Y; Shinohara, K; Takahashi, T; Tominaga, T, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahagi, S | 1 |
| Shindo, H | 1 |
| Watanabe, M | 1 |
| Kameyoshi, Y | 1 |
| Hide, M | 1 |
| Hsu, CY | 1 |
| Lee, FY | 1 |
| Huo, TI | 1 |
| Chan, CY | 1 |
| Huang, HC | 1 |
| Lin, HC | 1 |
| Chang, CC | 1 |
| Teng, TH | 1 |
| Wang, SS | 1 |
| Lee, SD | 1 |
| Suto, S | 1 |
| Okuaki, Y | 1 |
| Matsuoka, M | 1 |
| Enomoto, Y | 1 |
| Tsuruta, Y | 1 |
| Miyagawa, Y | 1 |
| Saito, A | 1 |
| Aizawa, Y | 1 |
| Toda, G | 1 |
| Jiang, PH | 1 |
| Motoo, Y | 1 |
| Iovanna, JL | 1 |
| Pébusque, MJ | 1 |
| Xie, MJ | 1 |
| Okada, G | 1 |
| Sawabu, N | 1 |
| Tympner, F | 1 |
| Rösch, W | 1 |
| Yamamoto, Y | 1 |
| Ito, N | 1 |
| Kawata, S | 1 |
| Tamura, S | 1 |
| Kiso, S | 1 |
| Tsushima, H | 1 |
| Maeda, Y | 1 |
| Yamasaki, E | 1 |
| Igura, T | 1 |
| Matsuzawa, Y | 1 |
| Sugiyama, M | 2 |
| Kobori, O | 1 |
| Atomi, Y | 2 |
| Wada, N | 2 |
| Kuroda, A | 2 |
| Muto, T | 2 |
| Kataoka, K | 1 |
| Sasaki, T | 1 |
| Yorizumi, H | 1 |
| Sakagami, J | 1 |
| Kashima, K | 1 |
| Yoneda, K | 1 |
| Amano, I | 1 |
| Tanaka, H | 1 |
| Yagi, H | 1 |
| Tsukaguchi, N | 1 |
| Morii, T | 1 |
| Narita, N | 1 |
| Fukuda, N | 1 |
| Shimohakamada, Y | 1 |
| Nakamori, Y | 1 |
| Tominaga, T | 1 |
| Shinohara, K | 1 |
| Takahashi, T | 1 |
| Oeda, E | 1 |
| Sato, Y | 1 |
| Takeda, K | 1 |
2 reviews available for gabexate and Chronic Illness
| Article | Year |
|---|---|
[A case of groove pancreatitis pure type treated with conservative therapy].
Topics: Chronic Disease; Drug Therapy, Combination; Esters; Gabexate; Guanidines; Humans; Magnetic Resonance | 2003 |
[Clinical study of chronic pancreatitis].
Topics: Alcohol Drinking; Cholangiopancreatography, Endoscopic Retrograde; Chronic Disease; Esters; Fasting; | 1993 |
1 trial available for gabexate and Chronic Illness
| Article | Year |
|---|---|
[Effect of secretin and gabexate-mesilate (synthetic protease inhibitor) on serum amylase level after ERCP].
Topics: Alkaline Phosphatase; Amylases; Cholangiopancreatography, Endoscopic Retrograde; Chronic Disease; Do | 1982 |
11 other studies available for gabexate and Chronic Illness
| Article | Year |
|---|---|
Refractory chronic urticaria treated effectively with the protease inhibitors, nafamostat mesilate and camostat mesilate.
Topics: Adult; Benzamidines; Chronic Disease; Drug Therapy, Combination; Esters; Female; Gabexate; Guanidine | 2010 |
Lack of therapeutic effects of gabexate mesilate on the hepatic encephalopathy in rats with acute and chronic hepatic failure.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Blood Pressure; Chronic Disease; Common Bile Duct; Di | 2010 |
Tumor protein p53-induced nuclear protein 1 (TP53INP1) in spontaneous chronic pancreatitis in the WBN/Kob rat: drug effects on its expression in the pancreas.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Arginine; Carrier Proteins; Cell Line; Chronic Di | 2004 |
Induction of interleukin-6 by interferon alfa and its abrogation by a serine protease inhibitor in patients with chronic hepatitis C.
Topics: 2',5'-Oligoadenylate Synthetase; Adult; Aged; Base Sequence; Chronic Disease; Female; Gabexate; Hepa | 1996 |
Effect of oral administration of protease inhibitor on pancreatic exocrine function in WBN/Kob rats with chronic pancreatitis.
Topics: Administration, Oral; Animals; Cholecystokinin; Chronic Disease; Disease Models, Animal; Esters; Gab | 1996 |
Effect of oral protease inhibitor administration on gallbladder motility in patients with mild chronic pancreatitis.
Topics: Administration, Oral; Adult; Aged; Cholecystokinin; Chronic Disease; Esters; Female; Gabexate; Gallb | 1997 |
Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct.
Topics: Amylases; Animals; Blood Glucose; Body Weight; Chronic Disease; Disease Models, Animal; Esters; Gabe | 1998 |
[Effective use of camostat mesilate for chronic disseminated intravascular coagulation complicated by thoracoabdominal aortic aneurysm].
Topics: Administration, Oral; Aged; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Chronic Disease; | 2001 |
[Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin].
Topics: Administration, Oral; Aged; Anticoagulants; Aortic Aneurysm, Thoracic; Aspirin; Chronic Disease; Dis | 2002 |
[Protease inhibitors in the treatment of pancreatitis].
Topics: Acute Disease; Animals; Aprotinin; Chronic Disease; Esters; Gabexate; Glycoproteins; Guanidines; Hum | 1991 |
[The Pancreas Study Group: Inhibition of pancreas secretion and trypsin activity. Mechanisms and importance of therapy of acute and chronic pancreatitis].
Topics: Adult; Animals; Aprotinin; Bicarbonates; Cholecystokinin; Chronic Disease; Dogs; Female; Gabexate; G | 1987 |