gabexate has been researched along with Chemical and Drug Induced Liver Injury in 2 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a case of autoimmune hepatitis (AIH) that may have occurred following drug-induced liver injury with camostat mesilate and/or benzbromarone in an elderly patient." | 1.43 | Autoimmune hepatitis following drug-induced liver injury in an elderly patient. ( Arai, M; Haga, Y; Iino, Y; Kanda, T; Kumagai, J; Nakamoto, S; Nakamura, M; Sasaki, R; Wu, S; Yasui, S; Yokosuka, O, 2016) |
| "Gabexate mesilate treatment significantly decreased the elevation of serum transaminase levels and improved liver histology 24 h after the administration of CCl4 (0." | 1.33 | Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats. ( Goto, T; Kataoka, E; Lin, JG; Mikami, K; Miura, K; Ohshima, S; Segawa, D; Shibuya, T; Watanabe, D; Watanabe, S; Yoneyama, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumagai, J | 1 |
| Kanda, T | 1 |
| Yasui, S | 1 |
| Haga, Y | 1 |
| Sasaki, R | 1 |
| Nakamura, M | 1 |
| Wu, S | 1 |
| Nakamoto, S | 1 |
| Arai, M | 1 |
| Iino, Y | 1 |
| Yokosuka, O | 1 |
| Mikami, K | 1 |
| Goto, T | 1 |
| Miura, K | 1 |
| Ohshima, S | 1 |
| Yoneyama, K | 1 |
| Lin, JG | 1 |
| Watanabe, D | 1 |
| Segawa, D | 1 |
| Kataoka, E | 1 |
| Shibuya, T | 1 |
| Watanabe, S | 1 |
2 other studies available for gabexate and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Autoimmune hepatitis following drug-induced liver injury in an elderly patient.
Topics: Aged; Benzbromarone; Biopsy; Chemical and Drug Induced Liver Injury; Esters; Gabexate; Guanidines; H | 2016 |
Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Disea | 2005 |