Page last updated: 2024-10-27

gabexate and Blood Poisoning

gabexate has been researched along with Blood Poisoning in 4 studies

Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Research Excerpts

ExcerptRelevanceReference
" We retrospectively evaluated and compared the efficacies of rhTM and gabexate mesilate (GM) in patients diagnosed with sepsis-induced DIC."7.80A retrospective comparative study of recombinant human thrombomodulin and gabexate mesilate in sepsis-induced disseminated intravascular coagulation patients. ( Imamura, Y; Izumikawa, K; Kohno, S; Matsuo, N; Miyazaki, T; Nakamura, S; Sawai, T; Suyama, N; Takazono, T; Yanagihara, K; Yoshioka, S, 2014)
" We retrospectively evaluated and compared the efficacies of rhTM and gabexate mesilate (GM) in patients diagnosed with sepsis-induced DIC."3.80A retrospective comparative study of recombinant human thrombomodulin and gabexate mesilate in sepsis-induced disseminated intravascular coagulation patients. ( Imamura, Y; Izumikawa, K; Kohno, S; Matsuo, N; Miyazaki, T; Nakamura, S; Sawai, T; Suyama, N; Takazono, T; Yanagihara, K; Yoshioka, S, 2014)
"Whereas in DIC associated with trauma, since balance between coagulation and fibrinolysis collapses drastically in a short period, both anticoagulantion therapy and antifibrinolytic therapy can be utilized depending on clinical conditions."2.53[Anti DIC therapy]. ( Sakamoto, Y; Yahata, M, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gando, S1
Saitoh, D1
Ishikura, H1
Ueyama, M1
Otomo, Y1
Oda, S1
Kushimoto, S1
Tanjoh, K1
Mayumi, T1
Ikeda, T1
Iba, T1
Eguchi, Y1
Okamoto, K1
Ogura, H1
Koseki, K1
Sakamoto, Y2
Takayama, Y1
Shirai, K1
Takasu, O1
Inoue, Y1
Mashiko, K1
Tsubota, T1
Endo, S1
Takazono, T1
Nakamura, S1
Imamura, Y1
Yoshioka, S1
Miyazaki, T1
Izumikawa, K1
Sawai, T1
Matsuo, N1
Yanagihara, K1
Suyama, N1
Kohno, S1
Akahoshi, T1
Sugimori, H1
Kaku, N1
Tokuda, K1
Nagata, T1
Noda, E1
Morita, M1
Hashizume, M1
Maehara, Y1
Yahata, M1

Reviews

1 review available for gabexate and Blood Poisoning

ArticleYear
[Anti DIC therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:2

    Topics: Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzamidines; Disseminated Intravascular Coa

2016

Trials

1 trial available for gabexate and Blood Poisoning

ArticleYear
A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis.
    Critical care (London, England), 2013, Dec-16, Volume: 17, Issue:6

    Topics: Aged; Antithrombins; Blood Coagulation; Disseminated Intravascular Coagulation; Drug Administration

2013

Other Studies

2 other studies available for gabexate and Blood Poisoning

ArticleYear
A retrospective comparative study of recombinant human thrombomodulin and gabexate mesilate in sepsis-induced disseminated intravascular coagulation patients.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2014, Volume: 20, Issue:8

    Topics: Aged; Aged, 80 and over; Analysis of Variance; C-Reactive Protein; Disseminated Intravascular Coagul

2014
Comparison of recombinant human thrombomodulin and gabexate mesylate for treatment of disseminated intravascular coagulation (DIC) with sepsis following emergent gastrointestinal surgery: a retrospective study.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2015, Volume: 41, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Critical Care; Disseminated Intravascular Coagulatio

2015