gabexate has been researched along with Asthma, Bronchial in 2 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Excerpt | Relevance | Reference |
---|---|---|
"We sought to investigate the effects of serine protease inhibitors nafamostat mesilate (FUT), gabexate mesilate (FOY), and ulinastatin (UTI) on airway inflammation in a mouse model of allergic asthma." | 7.73 | Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma. ( Chen, CL; Kao, ST; Lin, KJ; Tani, T; Wang, JY; Wang, SD; Yu, CK; Zeng, ZY, 2006) |
" However, the effects of the serine protease inhibitors nafamostat mesilate (FUT), gabexate mesilate (FOY), and ulinastatin (UTI) on a long-term challenged mouse model of chronic asthma are unclear." | 3.80 | The effect of serine protease inhibitors on airway inflammation in a chronic allergen-induced asthma mouse model. ( Chao, YP; Chiang, CJ; Kao, ST; Lin, CC; Lin, J; Lin, LJ; Wang, SD, 2014) |
"We sought to investigate the effects of serine protease inhibitors nafamostat mesilate (FUT), gabexate mesilate (FOY), and ulinastatin (UTI) on airway inflammation in a mouse model of allergic asthma." | 3.73 | Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma. ( Chen, CL; Kao, ST; Lin, KJ; Tani, T; Wang, JY; Wang, SD; Yu, CK; Zeng, ZY, 2006) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lin, CC | 1 |
Lin, LJ | 1 |
Wang, SD | 2 |
Chiang, CJ | 1 |
Chao, YP | 1 |
Lin, J | 1 |
Kao, ST | 2 |
Chen, CL | 1 |
Zeng, ZY | 1 |
Lin, KJ | 1 |
Tani, T | 1 |
Yu, CK | 1 |
Wang, JY | 1 |
2 other studies available for gabexate and Asthma, Bronchial
Article | Year |
---|---|
The effect of serine protease inhibitors on airway inflammation in a chronic allergen-induced asthma mouse model.
Topics: Allergens; Animals; Asthma; Benzamidines; Disease Models, Animal; Gabexate; Glycoproteins; Guanidine | 2014 |
Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma.
Topics: Animals; Antigens, Dermatophagoides; Arthropod Proteins; Asthma; Benzamidines; Chemokines; Cysteine | 2006 |