gabexate has been researched along with Angiogenesis, Pathologic in 4 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bone metastases from gastric cancer (GC) are considered a relatively uncommon finding; however, they are related to poorer prognosis." | 2.52 | Targeting mast cells in gastric cancer with special reference to bone metastases. ( Ammendola, M; De Sarro, G; Gadaleta, CD; Leporini, C; Marech, I; Oakley, C; Ranieri, G; Russo, E; Sacco, R; Sammarco, G, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ammendola, M | 2 |
| Leporini, C | 2 |
| Marech, I | 2 |
| Gadaleta, CD | 2 |
| Scognamillo, G | 1 |
| Sacco, R | 2 |
| Sammarco, G | 2 |
| De Sarro, G | 2 |
| Russo, E | 2 |
| Ranieri, G | 2 |
| Oakley, C | 1 |
| Brandi, G | 1 |
| Tavolari, S | 1 |
| De Rosa, F | 1 |
| Di Girolamo, S | 1 |
| Agostini, V | 1 |
| Barbera, MA | 1 |
| Frega, G | 1 |
| Biasco, G | 1 |
| Yoon, WH | 1 |
| Jung, YJ | 1 |
| Kim, TD | 1 |
| Li, G | 1 |
| Park, BJ | 1 |
| Kim, JY | 1 |
| Lee, YC | 1 |
| Kim, JM | 1 |
| Park, JI | 1 |
| Park, HD | 1 |
| No, ZS | 1 |
| Lim, K | 1 |
| Hwang, BD | 1 |
| Kim, YS | 1 |
2 reviews available for gabexate and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Targeting mast cells tryptase in tumor microenvironment: a potential antiangiogenetic strategy.
Topics: Angiogenesis Inhibitors; Cell Proliferation; Gabexate; Humans; Inflammation; Mast Cells; Neoplasms; | 2014 |
Targeting mast cells in gastric cancer with special reference to bone metastases.
Topics: Animals; Antigens, CD34; Benzamides; Benzamidines; Bone and Bones; Bone Neoplasms; Bone Resorption; | 2015 |
2 other studies available for gabexate and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Antitumoral efficacy of the protease inhibitor gabexate mesilate in colon cancer cells harbouring KRAS, BRAF and PIK3CA mutations.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Com | 2012 |
Gabexate mesilate inhibits colon cancer growth, invasion, and metastasis by reducing matrix metalloproteinases and angiogenesis.
Topics: Animals; Capillaries; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Culture | 2004 |