gabexate has been researched along with Adenocarcinoma in 8 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sequential therapy consisting of methotrexate (MTX) and 5-FU was performed together with the administration of heparin and FOY in 10 cases of gastric cancer with disseminated intravascular coagulation (DIC) causing systemic bone metastasis." | 3.68 | [Sequential MTX and 5-FU therapy of gastric cancer with systemic bone metastasis and disseminated intravascular coagulation]. ( Ibuka, T; Imai, K; Ishiwata, J; Kobayashi, T; Monma, K; Ohno, T; Onozawa, Y; Sakaki, N; Sasaki, T; Tabata, I, 1992) |
| "Transforming growth factor beta1 (TGF-beta1) is a multifunctional poly-peptide that regulates cell growth and differentiation, ECM deposition, cellular adhesion properties, angiogenesis, and also immune functions." | 1.32 | Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells. ( Hirakawa, K; Maeda, K; Nishihara, T; Ohira, M; Sawada, T; Uchima, Y, 2004) |
| "Thirty-four paired normal and gastric cancer tissues were tested to measure the IC50 of the gabexate mesylate." | 1.31 | Biological phenotype determination with ex vivo model in gastric cancer for matrix-metalloproteinase inhibitor treatment. ( Chung, HC; Jeung, HC; Kim, BS; Kim, JJ; Min, JS; Noh, SH; Rha, SY; Roh, JK, 2002) |
| "A case of advanced gastric cancer associated with metastatic carcinomatosis of the bone marrow, microangiopathic hemolytic anemia (MAHA) and disseminated intravascular coagulation (DIC) was reported." | 1.27 | [Microangiopathic hemolytic anemia associated with gastric cancer]. ( Hattori, T; Kanou, T; Kuramoto, J; Miura, K; Niimoto, M; Nosou, Y; Yanagawa, E; Yoshinaka, K, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rha, SY | 1 |
| Jeung, HC | 1 |
| Roh, JK | 1 |
| Kim, JJ | 1 |
| Noh, SH | 1 |
| Min, JS | 1 |
| Kim, BS | 1 |
| Chung, HC | 1 |
| Uchima, Y | 2 |
| Sawada, T | 2 |
| Nishihara, T | 1 |
| Maeda, K | 1 |
| Ohira, M | 1 |
| Hirakawa, K | 2 |
| Ohkoshi, M | 1 |
| Furukawa, F | 1 |
| Nishikawa, A | 1 |
| Imazawa, T | 1 |
| Yoshimura, H | 1 |
| Sato, M | 1 |
| Aze, Y | 1 |
| Takahashi, M | 1 |
| Manabe, T | 1 |
| Asano, N | 1 |
| Yoshimura, T | 1 |
| Suwa, H | 1 |
| Imamura, T | 1 |
| Ohshio, G | 1 |
| Kobayashi, T | 1 |
| Sasaki, T | 1 |
| Ibuka, T | 1 |
| Imai, K | 1 |
| Monma, K | 1 |
| Sakaki, N | 1 |
| Tabata, I | 1 |
| Ishiwata, J | 1 |
| Onozawa, Y | 1 |
| Ohno, T | 1 |
| Kanou, T | 1 |
| Nosou, Y | 1 |
| Yoshinaka, K | 1 |
| Yanagawa, E | 1 |
| Niimoto, M | 1 |
| Hattori, T | 1 |
| Miura, K | 1 |
| Kuramoto, J | 1 |
1 review available for gabexate and Adenocarcinoma
| Article | Year |
|---|---|
[Protease inhibitors as anticancer chemotherapy--experimental and clinical studies].
Topics: Adenocarcinoma; Animals; Carcinoma, Lewis Lung; Carcinoma, Squamous Cell; Cell Division; Colonic Neo | 1995 |
7 other studies available for gabexate and Adenocarcinoma
| Article | Year |
|---|---|
Biological phenotype determination with ex vivo model in gastric cancer for matrix-metalloproteinase inhibitor treatment.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Cell Differentiation; Enzyme Inhibitors | 2002 |
Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells.
Topics: Adenocarcinoma; Animals; Cell Division; Cell Line, Tumor; Collagen; Drug Combinations; Enzyme Induct | 2004 |
Action of antiproteases on pancreatic cancer cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Extracellular Matrix; Gabexate; Humans; Neopla | 2007 |
Blocking effects of synthetic trypsin inhibitor (camostat) on pancreatic carcinogenesis in hamsters initiated with N-nitrosobis(2-oxopropyl)amine.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Esters; Female; Gabexate; Guanidines; Mesocricetus | 1994 |
Effect of synthetic protease inhibitor on histologic changes and free radical activity in hamsters with pancreatic cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Animals; Carcinogens; Cricetinae; Esters; Free Radical Sc | 1993 |
[Sequential MTX and 5-FU therapy of gastric cancer with systemic bone metastasis and disseminated intravascular coagulation].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 1992 |
[Microangiopathic hemolytic anemia associated with gastric cancer].
Topics: Adenocarcinoma; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Benzodiazep | 1986 |