gabexate has been researched along with Acute Respiratory Distress Syndrome in 6 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the effects of gabexate mesilate (FOY), a protease inhibitor, on a canine model of pulmonary ischemia-reperfusion injury." | 7.70 | Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs. ( Chen, JS; Kuo, SH; Lee, YC; Lin-Shiau, SY; Luh, SP; Shau, WY; Tsai, CC, 1999) |
| "To assess the effects of gabexate mesilate (FOY), a protease inhibitor, on a canine model of pulmonary ischemia-reperfusion injury." | 3.70 | Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs. ( Chen, JS; Kuo, SH; Lee, YC; Lin-Shiau, SY; Luh, SP; Shau, WY; Tsai, CC, 1999) |
| "In order to determine whether gabexate mesilate, a synthetic protease inhibitor with anticoagulant properties, is useful for the treatment of adult respiratory distress syndrome, we examined its effect on endotoxin-induced pulmonary vascular injury in rats." | 3.69 | Gabexate mesilate, a synthetic protease inhibitor, attenuates endotoxin-induced pulmonary vascular injury by inhibiting tumor necrosis factor production by monocytes. ( Murakami, K; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okumura, Y | 1 |
| Inoue, H | 2 |
| Fujiyama, Y | 1 |
| Bamba, T | 1 |
| Murakami, K | 1 |
| Okajima, K | 1 |
| Uchiba, M | 1 |
| Okabe, H | 1 |
| Takatsuki, K | 1 |
| Shinohara, T | 1 |
| Hidaka, T | 1 |
| Matsuki, Y | 1 |
| Suzuki, K | 1 |
| Ohsuzu, F | 1 |
| Luh, SP | 1 |
| Tsai, CC | 1 |
| Shau, WY | 1 |
| Chen, JS | 1 |
| Kuo, SH | 1 |
| Lin-Shiau, SY | 1 |
| Lee, YC | 1 |
| Motoki, R | 1 |
| Miyazawa, T | 1 |
| Tanemori, N | 1 |
| Utsumi, T | 1 |
| Katayama, S | 1 |
| Furukawa, N | 1 |
6 other studies available for gabexate and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Effects of serine protease inhibitors on accumulation of polymorphonuclear leukocytes in the lung induced by acute pancreatitis in rats.
Topics: Acute Disease; Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Disease Models, Animal; Endot | 1995 |
Gabexate mesilate, a synthetic protease inhibitor, attenuates endotoxin-induced pulmonary vascular injury by inhibiting tumor necrosis factor production by monocytes.
Topics: Animals; Capillary Permeability; Escherichia coli; Gabexate; Lipopolysaccharides; Male; Monocytes; P | 1996 |
Calcinosis cutis and intestinal pseudoobstruction in a patient with adult onset Still's disease associated with recurrent relapses of disordered coagulopathy.
Topics: Anticoagulants; Calcinosis; Diagnosis, Differential; Disseminated Intravascular Coagulation; Drug Th | 1999 |
Effects of gabexate mesilate (FOY) on ischemia-reperfusion-induced acute lung injury in dogs.
Topics: Animals; Bronchoalveolar Lavage Fluid; Dogs; Gabexate; Hemodynamics; Ischemia; Lung; Neutrophils; Pe | 1999 |
[Protease inhibitors in shock].
Topics: Aprotinin; Disseminated Intravascular Coagulation; Gabexate; Glycoproteins; Humans; Infant, Newborn; | 1991 |
[Balloon occlusion pulmonary angiography and anticoagulant-antithrombotic therapy in ARDS-associated pulmonary vascular thrombosis].
Topics: Adult; Aged; Gabexate; Guanidines; Heparin; Humans; Male; Middle Aged; Pulmonary Artery; Pulmonary E | 1991 |