gabexate has been researched along with Acute Lung Injury in 1 studies
Gabexate: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gabexate mesilate (GM) is a synthetic protease inhibitor with some anti-inflammatory action." | 5.37 | Gabexate mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury. ( Hagiwara, S; Hidaka, S; Iwasaka, H; Noguchi, T, 2011) |
| "Gabexate mesilate (GM) is a synthetic protease inhibitor with some anti-inflammatory action." | 1.37 | Gabexate mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury. ( Hagiwara, S; Hidaka, S; Iwasaka, H; Noguchi, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hidaka, S | 1 |
| Iwasaka, H | 1 |
| Hagiwara, S | 1 |
| Noguchi, T | 1 |
1 other study available for gabexate and Acute Lung Injury
| Article | Year |
|---|---|
Gabexate mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury.
Topics: Acute Lung Injury; Animals; DNA; Gabexate; HMGB1 Protein; Interleukin-6; Lipopolysaccharides; Lung; | 2011 |