Page last updated: 2024-10-27

gabapentin and Uterine Diseases

gabapentin has been researched along with Uterine Diseases in 2 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Uterine Diseases: Pathological processes involving any part of the UTERUS.

Research Excerpts

ExcerptRelevanceReference
"To review the literature examining the use of gabapentin for treatment of hot flashes during natural or surgically induced menopause."8.87Use of gabapentin for the management of natural or surgical menopausal hot flashes. ( Carroll, DG; Hayes, LP; Kelley, KW, 2011)
"To review the literature examining the use of gabapentin for treatment of hot flashes during natural or surgically induced menopause."4.87Use of gabapentin for the management of natural or surgical menopausal hot flashes. ( Carroll, DG; Hayes, LP; Kelley, KW, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Huynh, TQ1
Patel, NR1
Goldstein, ND1
Makai, GE1
Hayes, LP1
Carroll, DG1
Kelley, KW1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind Randomized Placebo-Controlled Clinical Trial of Preoperative Gabapentin Prior to Vaginal Apical Suspension Prolapse Procedures[NCT05658887]Phase 4110 participants (Anticipated)Interventional2023-01-01Enrolling by invitation
Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management[NCT02703259]Phase 4137 participants (Actual)Interventional2016-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Narcotic Use at 2 Weeks Postop

Assessment of the amount of narcotic use postoperatively at 2 weeks. will use opioid equivalence table to convert all narcotic use to oxycodone equivalents (NCT02703259)
Timeframe: 2 weeks

Interventionmorphine milligram equivalents (Mean)
Gabapentin167.2
Control187.3

Narcotic Use at 24 Hours Postop

Assessment of the amount of narcotic use postoperatively at 24 hours. will use opioid equivalence table to convert all narcotic use to oxycodone equivalents (NCT02703259)
Timeframe: 24 hours

Interventionmorphine milligram equivalents (Mean)
Gabapentin158.8
Control175.0

Subjective Pain at 2 Weeks Postop

"Assessment of the subject pain score postoperatively at 2 weeks. will use a numeric analog scale from 0-10.~The pain scale ranging from 0-10 with 0 representing No Pain and 10 representing the Worst Pain Possible" (NCT02703259)
Timeframe: 2 weeks

Interventionscore on a scale (Mean)
Gabapentin1.3
Control1.4

Subjective Pain at 24 Hours Postoperative

Pain score assesses patient subjective pain via patient reported numeric analogue scale, range 0-10 with 0 being no pain and 10 being severe pain. (NCT02703259)
Timeframe: 24 hours

Interventionscore on a scale (Mean)
Gabapentin3.4
Control3.4

Number of Patient With Gabapentin Adverse Effects at 2 Weeks Postoperatively

Will assess for known symptoms of gabapentin postoperatively at 2 weeks. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction (NCT02703259)
Timeframe: 2 weeks

,
InterventionParticipants (Count of Participants)
DizzinessBlurred visionSomnolenceDifficulty walkingTremulousnessNauseaVomiting
Control83215271
Gabapentin1241854120

Number of Patient With Gabapentin Adverse Effects at 24 Hours Postoperatively

Will assess for known symptoms of gabapentin postoperatively at 24 hours. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction (NCT02703259)
Timeframe: 24 hours

,
InterventionParticipants (Count of Participants)
DizzinessBlurred VisionSomnolenceDifficulty walkingTremulousnessNauseaVomiting
Control84231162515
Gabapentin177201311249

Reviews

1 review available for gabapentin and Uterine Diseases

ArticleYear
Use of gabapentin for the management of natural or surgical menopausal hot flashes.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:3

    Topics: Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyri

2011

Trials

1 trial available for gabapentin and Uterine Diseases

ArticleYear
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
    Journal of minimally invasive gynecology, 2021, Volume: 28, Issue:2

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration

2021
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
    Journal of minimally invasive gynecology, 2021, Volume: 28, Issue:2

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration

2021
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
    Journal of minimally invasive gynecology, 2021, Volume: 28, Issue:2

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration

2021
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
    Journal of minimally invasive gynecology, 2021, Volume: 28, Issue:2

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration

2021