Page last updated: 2024-10-27

gabapentin and Tongue Neoplasms

gabapentin has been researched along with Tongue Neoplasms in 3 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Tongue Neoplasms: Tumors or cancer of the TONGUE.

Research Excerpts

Excerpt	Relevance	Reference
"Postoperative pain was reduced in the gabapentin group (1."	2.77	Analgesic effects of preoperative gabapentin after tongue reconstruction with the anterolateral thigh flap. ( Burd, A; Chiu, TW; Lau, EY; Leung, CC, 2012)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Oberoi-Jassal, R	1
Portman, D	1
Smith, J	1
Rajasekhara, S	1
Desai, VV	1
Donovan, KA	1
Chang, YD	1
Touchette, D	1
Gessler, EM	1
Chiu, TW	1
Leung, CC	1
Lau, EY	1
Burd, A	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Gabapentin Regimens and Their Effects on Opioid Consumption[NCT03334903]			Phase 4	77 participants (Actual)	Interventional	2018-05-15	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

"VAS Score 1: How Much Pain do You Feel in Your Operative Site When Resting?"

Surgical site pain. Scale 0-10, with 0 best and 10 worst (NCT03334903)
Timeframe: 2-3 months after surgery (at 2nd postoperative appointment)

Intervention	score on 10-point scale (Mean)
Standard of Care	2.26
Postoperative Gabapentin Regimen	2.46

"VAS Score 2: How Much Pain do You Feel in Your Operative Site When Moving?"

Surgical site pain. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Intervention	score on a 10-point scale (Mean)
Standard of Care	3.84
Postoperative Gabapentin Regimen	3.54

"VAS Score 3: How Well Are You Sleeping?"

Sleep quality. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Intervention	score on a 10-point scale (Mean)
Standard of Care	5.73
Postoperative Gabapentin Regimen	6.38

"VAS Score 4: How Bad is Your Nausea?"

Nausea. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Intervention	score on a 10-point scale (Mean)
Standard of Care	0.36
Postoperative Gabapentin Regimen	0.17

"VAS Score 5: How Satisfied Are You With Your Pain Management?"

Satisfaction. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Intervention	score on a 10-point scale (Mean)
Standard of Care	7.83
Postoperative Gabapentin Regimen	8.48

Days Taking Opioids

Number of days until patients are finished consuming opioid medications after discharge. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Intervention	days (Mean)
Standard of Care	14.8
Postoperative Gabapentin Regimen	18.7

Opioid Consumption

Mean opioid consumption, measured in mg of morphine equivalents. (NCT03334903)
Timeframe: 2-3 months following surgery (total amount measured at second postoperative appointment; means assessed afterwards).

Intervention	morphine equivalents (Mean)
Standard of Care	287.0
Postoperative Gabapentin Regimen	281.1

Trials

1 trial available for gabapentin and Tongue Neoplasms

Article	Year
Analgesic effects of preoperative gabapentin after tongue reconstruction with the anterolateral thigh flap. Hong Kong medical journal = Xianggang yi xue za zhi, 2012, Volume: 18, Issue:1 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amines; Analgesia, Patient-Controlled; Analges	2012

Other Studies

2 other studies available for gabapentin and Tongue Neoplasms

Article	Year
Burning Mouth Pain: A Case Report. Journal of oncology practice, 2018, Volume: 14, Issue:7 Topics: Analgesics; Burning Mouth Syndrome; Carcinoma, Squamous Cell; Clonazepam; Female; Fentanyl; Gabapent	2018
Painful traumatic neuroma of the tongue treated with serial alcohol injections. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2011, Volume: 145, Issue:4 Topics: Aged; Amines; Analgesics; Anesthetics, Local; Central Nervous System Depressants; Cyclohexanecarboxy	2011