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gabapentin and Status Epilepticus

gabapentin has been researched along with Status Epilepticus in 11 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

Research Excerpts

ExcerptRelevanceReference
"The lithium-pilocarpine model of epilepsy reproduces in rodents several features of human temporal lobe epilepsy, by inducing an acute status epilepticus (SE) followed by a latency period."7.79Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. ( Angelo, MF; Lukin, J; Ramos, AJ; Rossi, AR; Villarreal, A, 2013)
"To evaluate the effects of high-frequency electrical stimulation (HFS) in both ventral hippocampi, alone and combined with a subeffective dose of antiepileptic drugs, during the status epilepticus (SE) induced by lithium-pilocarpine (LP)."7.76Antiepileptic drugs combined with high-frequency electrical stimulation in the ventral hippocampus modify pilocarpine-induced status epilepticus in rats. ( Alcantara-Gonzalez, D; Cuellar-Herrera, M; Neri-Bazan, L; Peña, F; Rocha, L, 2010)
"This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats."7.74Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats. ( Assis, MA; Fonteles, MM; Freitas, RL; Freitas, RM; Pereira, MB; Silva, RF; Takahashi, RN, 2007)
"This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats."7.73Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus. ( Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS, 2006)
") gabapentin (GBP), carbamazepine (CBZ) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) on learning and memory, anxiety, and locomotor activity in rats with lithium-pilocarpine-induced status epilepticus (SE)."3.83Immediate and delayed treatment with gabapentin, carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithium-pilocarpine model in rats. ( Gulec Suyen, G; Isbil-Buyukcoskun, N; Kahveci, N; Ozluk, K; Sengun, E, 2016)
"The lithium-pilocarpine model of epilepsy reproduces in rodents several features of human temporal lobe epilepsy, by inducing an acute status epilepticus (SE) followed by a latency period."3.79Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. ( Angelo, MF; Lukin, J; Ramos, AJ; Rossi, AR; Villarreal, A, 2013)
"To evaluate the effects of high-frequency electrical stimulation (HFS) in both ventral hippocampi, alone and combined with a subeffective dose of antiepileptic drugs, during the status epilepticus (SE) induced by lithium-pilocarpine (LP)."3.76Antiepileptic drugs combined with high-frequency electrical stimulation in the ventral hippocampus modify pilocarpine-induced status epilepticus in rats. ( Alcantara-Gonzalez, D; Cuellar-Herrera, M; Neri-Bazan, L; Peña, F; Rocha, L, 2010)
"This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats."3.74Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats. ( Assis, MA; Fonteles, MM; Freitas, RL; Freitas, RM; Pereira, MB; Silva, RF; Takahashi, RN, 2007)
"This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats."3.73Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus. ( Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS, 2006)
"Guillain-Barré syndrome may result in hypertensive encephalopathy that can manifest as status epilepticus before the onset of motor symptoms."1.34Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome. ( Abend, NS; Bonnemann, CG; Licht, DJ, 2007)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (63.64)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Perez-Ramirez, MB1
Gu, F1
Prince, DA1
Rossi, AR1
Angelo, MF1
Villarreal, A1
Lukin, J1
Ramos, AJ1
Gulec Suyen, G1
Isbil-Buyukcoskun, N1
Kahveci, N1
Sengun, E1
Ozluk, K1
Cuellar-Herrera, M1
Peña, F1
Alcantara-Gonzalez, D1
Neri-Bazan, L1
Rocha, L1
Barrueto, F1
Green, J1
Howland, MA1
Hoffman, RS1
Nelson, LS1
Freitas, RM2
Sousa, FC1
Viana, GS1
Fonteles, MM2
Pereira, MB1
Freitas, RL1
Assis, MA1
Silva, RF1
Takahashi, RN1
Striano, P1
Coppola, A1
Madia, F1
Pezzella, M1
Ciampa, C1
Zara, F1
Striano, S1
Abend, NS1
Bonnemann, CG1
Licht, DJ1
Bhatia, R1
Vibha, D1
Srivastava, MV1
Prasad, K1
Tripathi, M1
Bhushan Singh, M1
Brouns, R1
Van Paesschen, W1

Other Studies

11 other studies available for gabapentin and Status Epilepticus

ArticleYear
Prolonged prophylactic effects of gabapentin on status epilepticus-induced neocortical injury.
    Neurobiology of disease, 2020, Volume: 142

    Topics: Animals; Anticonvulsants; Excitatory Postsynaptic Potentials; Gabapentin; Mice; Pyramidal Cells; Sen

2020
Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Amines; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Electroencephalography; Gabapentin; gamma-

2013
Immediate and delayed treatment with gabapentin, carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithium-pilocarpine model in rats.
    Pharmacology, biochemistry, and behavior, 2016, Volume: 148

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amines; Animals; Behavior, Animal; Carbamazepine; Cognition; C

2016
Antiepileptic drugs combined with high-frequency electrical stimulation in the ventral hippocampus modify pilocarpine-induced status epilepticus in rats.
    Epilepsia, 2010, Volume: 51, Issue:3

    Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stim

2010
Gabapentin withdrawal presenting as status epilepticus.
    Journal of toxicology. Clinical toxicology, 2002, Volume: 40, Issue:7

    Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Aci

2002
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.
    Neuroscience letters, 2006, Nov-13, Volume: 408, Issue:2

    Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri

2006
Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats.
    Neuroscience letters, 2007, Jun-04, Volume: 419, Issue:3

    Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Ga

2007
Life-threatening status epilepticus following gabapentin administration in a patient with benign adult familial myoclonic epilepsy.
    Epilepsia, 2007, Volume: 48, Issue:10

    Topics: Acute Disease; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Drug Resistanc

2007
Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome.
    Pediatric emergency care, 2007, Volume: 23, Issue:9

    Topics: Adolescent; Amines; Anticonvulsants; Antihypertensive Agents; Cyclohexanecarboxylic Acids; Diagnosis

2007
Use of propofol anesthesia and adjunctive treatment with levetiracetam and gabapentin in managing status epilepticus in a patient of acute intermittent porphyria.
    Epilepsia, 2008, Volume: 49, Issue:5

    Topics: Amines; Anesthetics, Intravenous; Anticonvulsants; Child; Comorbidity; Cyclohexanecarboxylic Acids;

2008
Recurrent complex partial status epilepticus associated with tiagabine rechallenge.
    Acta neurologica Belgica, 2002, Volume: 102, Issue:1

    Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response

2002