gabapentin has been researched along with Spastic Paraplegia, Hereditary in 1 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Spastic Paraplegia, Hereditary: A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with hereditary spastic paraplegia (HSP) are often treated with antispastic drugs to relieve symptoms but documentation is lacking." | 2.73 | Double-blind crossover trial of gabapentin in SPG4-linked hereditary spastic paraplegia. ( Fenger, K; Jennum, P; Nielsen, JE; Rogvi-Hansen, Bá; Scheuer, KH; Svenstrup, K; Werdelin, L, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scheuer, KH | 1 |
| Svenstrup, K | 1 |
| Jennum, P | 1 |
| Rogvi-Hansen, Bá | 1 |
| Werdelin, L | 1 |
| Fenger, K | 1 |
| Nielsen, JE | 1 |
1 trial available for gabapentin and Spastic Paraplegia, Hereditary
| Article | Year |
|---|---|
Double-blind crossover trial of gabapentin in SPG4-linked hereditary spastic paraplegia.
Topics: Adenosine Triphosphatases; Adult; Aged; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarb | 2007 |