Page last updated: 2024-10-27

gabapentin and Smoking Cessation

gabapentin has been researched along with Smoking Cessation in 5 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Smoking Cessation: Discontinuing the habit of SMOKING.

Research Excerpts

ExcerptRelevanceReference
"This 6-week, randomized, open-label pilot study estimated the treatment effect size of gabapentin (n = 17) compared with bupropion SR (n = 19) for smoking cessation, thereby allowing sample size calculations for a definitive comparison study."9.11A randomized, open-label pilot comparison of gabapentin and bupropion SR for smoking cessation. ( Crockford, D; El-Guebaly, N; Patten, S; White, WD, 2005)
"Gabapentin-treated participants exhibited lower abstinence rates than placebo-treated participants; however, this difference was not significant."6.75Gabapentin for smoking cessation. ( Croghan, IT; Ebbert, JO; Hays, JT; Schroeder, DR; Sood, A; Sood, R; Wyatt, KD, 2010)
"This 6-week, randomized, open-label pilot study estimated the treatment effect size of gabapentin (n = 17) compared with bupropion SR (n = 19) for smoking cessation, thereby allowing sample size calculations for a definitive comparison study."5.11A randomized, open-label pilot comparison of gabapentin and bupropion SR for smoking cessation. ( Crockford, D; El-Guebaly, N; Patten, S; White, WD, 2005)
"Gabapentin-treated participants exhibited lower abstinence rates than placebo-treated participants; however, this difference was not significant."2.75Gabapentin for smoking cessation. ( Croghan, IT; Ebbert, JO; Hays, JT; Schroeder, DR; Sood, A; Sood, R; Wyatt, KD, 2010)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Chaurasia, A1
Ishrat, S1
Tiwari, R1
Sood, A2
Ebbert, JO2
Wyatt, KD1
Croghan, IT2
Schroeder, DR2
Sood, R2
Hays, JT2
White, WD1
Crockford, D1
Patten, S1
El-Guebaly, N1
Vander Weg, MW1
Wong, GY1
Myrick, H1
Malcolm, R1
Henderson, S1
McCormick, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Gabapentin for Smoking Abstinence[NCT00578552]Phase 280 participants (Actual)Interventional2007-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Biochemically Confirmed 7-day Point Prevalence Abstinence From Tobacco

"Point prevalence tobacco abstinence was adjudicated if the following conditions were met: (a) self-reported tobacco abstinence for the previous 7 days with a negative response to the question Have you used any type of tobacco, even a puff, in the past 7 days? and (b) Expired Carbon Monoxide equal or less then 8 parts per million." (NCT00578552)
Timeframe: 12 weeks following start of medication

Interventionparticipants (Number)
Placebo5
Gabapentin - 1800 mg /Day4
Gabapentin - 2700 mg/Day0

Trials

4 trials available for gabapentin and Smoking Cessation

ArticleYear
Gabapentin for cessation of smoking and non-smoking tobacco habits in Indian population.
    Minerva dental and oral science, 2021, Volume: 70, Issue:3

    Topics: Gabapentin; Habits; Humans; Nicotiana; Smoking Cessation; Tobacco Use

2021
Gabapentin for smoking cessation.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2010, Volume: 12, Issue:3

    Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid

2010
A randomized, open-label pilot comparison of gabapentin and bupropion SR for smoking cessation.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2005, Volume: 7, Issue:5

    Topics: Adolescent; Adult; Amines; Bupropion; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Excit

2005
Gabapentin for smoking cessation: a preliminary investigation of efficacy.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2007, Volume: 9, Issue:2

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid;

2007

Other Studies

1 other study available for gabapentin and Smoking Cessation

ArticleYear
Gabapentin for misuse of homemade nicotine nasal spray.
    The American journal of psychiatry, 2001, Volume: 158, Issue:3

    Topics: Acetates; Administration, Intranasal; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapent

2001