Page last updated: 2024-10-27

gabapentin and Serotonin Syndrome

gabapentin has been researched along with Serotonin Syndrome in 3 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"Lamotrigine is a novel anticonvulsant drug which also stabilises mood in bipolar illness via an unknown mechanism."1.30Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats. ( Hagan, RM; Higgins, GA; Kirkby, D; Southam, E, 1998)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ekşi, MŞ1
Turgut, VU1
Özcan-Ekşi, EE1
Güngör, A1
Tükel Turgut, FN1
Pamir, MN1
Dizdarevic, A1
Bremer, N1
Southam, E1
Kirkby, D1
Higgins, GA1
Hagan, RM1

Other Studies

3 other studies available for gabapentin and Serotonin Syndrome

ArticleYear
Serotonin Syndrome Following Tramadol and Gabapentin Use After Spine Surgery.
    World neurosurgery, 2019, Volume: 126

    Topics: Aged; Analgesics; Gabapentin; Humans; Laminectomy; Male; Pain, Postoperative; Serotonin Syndrome; Sp

2019
Cervical Spinal Cord Stimulation with Concomitant Serotonin Norepinephrine Reuptake Inhibitor Therapy Leading to the Serotonin Syndrome.
    Pain medicine (Malden, Mass.), 2017, 06-01, Volume: 18, Issue:6

    Topics: Adult; Analgesics; Cervical Vertebrae; Clonidine; Complex Regional Pain Syndromes; Diclofenac; Drug

2017
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
    European journal of pharmacology, 1998, Sep-25, Volume: 358, Issue:1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine;

1998